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Congenital Heart Disease Imaging in Adults

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181. Imaging by 4 DFlow in Patients With Tetralogy of Fallot

Flow CMR for the assessment of these parameters (ventricular volume, ventricular systolic function, and regurgitation of the pulmonary pathway). Condition or disease Intervention/treatment Phase Congenital Heart Disease Procedure: magnetic resonance imaging Not Applicable Detailed Description: Congenital heart disease, or corrected heart disease requires regular, specialized follow-up throughout the life of these patients. Among the recommended examinations, cardiac MRI is the reference (...) Chirurgical Marie Lannelongue: Congenital heart disease Tetralogy of Fallot Imaging by 4D Flow, Magnetic resonance imaging Prevention of ventricular dysfunction Additional relevant MeSH terms: Layout table for MeSH terms Heart Diseases Heart Defects, Congenital Tetralogy of Fallot Cardiovascular Diseases Cardiovascular Abnormalities Congenital Abnormalities

2018 Clinical Trials

182. Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging

or hypersensitive reaction to dexmedetomidine Organ dysfunction, and significant developmental delays or behavior problems Cardiac arrhythmia Known. acyanotic congenital heart disease or children after cardiac interventional procedures for follow-up examination Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study (...) Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2018 Clinical Trials

183. Interactive Guided Ultrasound Examinations Done by Non-experts of Ultrasound Imaging

informed consent. All volunteers should be affiliated to the French Social Security. All volunteers will be scheduled for a routine transthoracic echocardiography exam in the echocardiography laboratory at the investigation site as part of standard care. Exclusion Criteria: Subjects with congenital heart diseases (except bicuspid aortic valve) Pregnant women Adults lacking decisional capacity Adults placed under a legal protection regime (guardianship, curatorship, judicial protection) Adults (...) Healthcare Information provided by (Responsible Party): Philips Healthcare Study Details Study Description Go to Brief Summary: This prospective study is a pilot study for evaluating a guidance system that aims to facilitate high-quality echocardiographic acquisitions. Condition or disease Intervention/treatment Phase Cardiac Disease Heart Failure Cardiac Ischemia Device: TransThoracic Echocardiography imaging Not Applicable Detailed Description: The primary objective of this study is to assess

2018 Clinical Trials

184. Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary Hypertension

to develop a multi-scale computational model of Pulmonary Hypertension, this clinical model will be calibrated using longitudinal, retrospectively and prospectively acquired human clinical data. Condition or disease Intervention/treatment Pulmonary Hypertension Congenital Heart Disease Pediatric Congenital Heart Disease Procedure: cardiac catheterization Radiation: Cardiac MRI Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 50 participants (...) and Vascular Surgery, University of Michigan ClinicalTrials.gov Identifier: Other Study ID Numbers: HUM00117706 First Posted: June 21, 2018 Last Update Posted: June 21, 2018 Last Verified: June 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Hypertension Heart Diseases Hypertension, Pulmonary Heart Defects, Congenital Vascular Diseases Cardiovascular

2018 Clinical Trials

185. Task Force 7: Pediatric Cardiology Fellowship Training in Pulmonary Hypertension, Advanced Heart Failure, and Transplantation

• Interactions and relationships between the right and left ventricles in normal physiology and in the setting of pul- monary vascular diseases • Pathophysiology of congenital heart disease with intra- cardiac or arterial level shunt, including Eisenmenger physiology • Physiology of the patient with pulmonary artery hypertension (PAH) that is due to pulmonary venous hypertension 2.2.2.2. Clinical Evaluation, Imaging, and Hemodynamics • Identify the common presenting symptoms and physical examination findings (...) in patients with PH with and with- out congenital heart disease. • Identify the common presenting signs and symptoms of right and left heart failure. • Indications, risks, and benefits of techniques commonly used to evaluate patients with PH, including electrocardi- ography, echocardiography, cardiac magnetic resonance imaging, cardiac computed tomography, ventilation, and perfusion lung scans • Indications, risks, and benefits of cardiac catheterization and vasodilator testing 2.2.2.3. Classification

2015 American Heart Association

186. A consensus document for the selection of lung transplant candidates: 2014 - An update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation

that this document is a consensus document rather than a guideline, grading of levels of evidence and recommendations was not undertaken. Instead, as noted previously, a comprehensive literature search and consensus expert opinion have been presented. In all instances, the Writing Committee adhered to the ISHLT Standards and Guidelines Document Development Protocol (update January 2013). General candidacy consid era tions Lung transplantation should be considered for adults with chronic, end-stage lung disease (...) and mortality, it is important to consider the overall sum of contraindications and comorbidities. The following lists are not intended to include all possible clinical scenarios but rather to highlight common areas of concern. Absolute contraindication s • Lung transplantation should not be offered to adults with a recent history of malignancy. A 2-year disease-free interval combined with a low predicted risk of recurrence after lung transplantation may be reasonable, for instance, in non-melanoma

2015 International Society for Heart and Lung Transplantation

187. SCAI/HFSA Clinical Expert Consensus Document on the Use of Invasive Hemodynamics for the Diagnosis and Management of Cardiovascular Disease

interpreting accurate hemodynamic data obtained in the cardiac catheterization laboratory. Valvular Heart Disease For patients with valvular heart disease, an invasive hemodynamic evaluation is recommended to resolve discrepancies between clinical findings and noninvasive imaging data when surgical or catheter‐based therapy is being considered. When a patient undergoes an invasive hemodynamic evaluation for valvular disease, a simultaneous study of multiple central cardiac chamber hemodynamics should (...) . Attention should be directed toward the relative rise in left and right atrial pressure (RAP) with exercise, because the ratio of RAP/PCWP with exercise can be highly informative in isolating which “side” of the heart and circulation is the predominantly diseased and has the least physiologic reserve. Congenital Heart Disease For most patients with shunt lesions, echocardiography performed by an experienced sonographer, with careful examination of the gradients and chamber morphology, is sufficient

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2017 Society for Cardiovascular Angiography and Interventions

188. AIM Clinical Appropriateness Guidelines for Genetic Testing for Hereditary Cardiac Disease

of symptoms. Dilated Cardiomyopathy Dilated cardiomyopathy (DCM) is characterized by enlargement of the left ventricle of the heart and systolic impairment, in the absence of abnormal loading conditions or coronary artery disease sufficient to cause global systolic dysfunction (Haas 2015). The symptoms of DCM are similar to heart failure including shortness of breath, chest pain/tightness, fainting episodes and cardiac arrhythmias. The most serious complication of DCM is sudden, irregular heart rhythms (...) cardiac conduction disease (i.e. first, second or third degree heart block) and/or family history of premature unexplained death. In addition, they state that genetic testing can be useful for patients with familial DCM to confirm diagnosis, to recognize those who are at highest risk of arrhythmia and syndromic PROPRIETARY Guidelines developed by, and used with permission from, Informed Medical Decisions, Inc. © 2017 Informed Medical Decisions, Inc. All Rights Reserved. 7 features, to facilitate

2017 AIM Specialty Health

189. Transthoracic Echocardiography in Adult Patients with Ischemic Stroke

abnormalities: Valvular heart disease (with and without AF), LA/LA atrial appendage thrombus, LV thrombus, prosthetic valve, atrial myxoma, akinetic LV segment (wall motion abnormality), cardiomyopathy, LA spontaneous echo contrast, ASA, mitral valve prolapse, mitral annulus calcification, mitral stenosis, and PFO. What is the cost effectiveness of transthoracic echocardiography for identifying cardiac sources of emboli in adult patients with ischemic stroke? No studies reported on the cost effectiveness (...) echocardiography and transoesophageal echocardiography for identifying cardiac sources of emboli in adult patients with ischemic stroke? A 2014 health technology assessment with systematic review and diagnostic meta-analysis 18 compared echocardiography with other diagnostic imaging methods (including TOE) for the detection of a cardiac risk factors for TIA or stroke. The reviewers searched MEDLINE, EMBASE, PsychINFO, Web of Science, the Cochrane Library, and CINAHL using terms related to stroke and TTE

2014 Canadian Agency for Drugs and Technologies in Health - Rapid Review

190. Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot. (PubMed)

Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot. Congestive hepatopathy and hepatocellular carcinoma is a serious complication after Fontan procedure. Liver fibrosis due to hepatic congestion could occur also in adult patients after repair of tetralogy of Fallot (rTOF). However, the incidence and severity remain unclear.A total of 111 patients with adult congenital heart disease between 2009 and 2016 were enrolled (...) pathological evidence of moderate and severe (F2 and F3) liver fibrosis and one had combined hepatocellular and cholangiocarcinoma.We first demonstrated elevated liver fibrosis markers in adult patients with rTOF. These levels may help to predict the progressive liver disease as well as consider the timing of pulmonary valve replacement.Copyright © 2019 Elsevier B.V. All rights reserved.

2019 International journal of cardiology

191. Mechanism and Risk Factors for Death in Adults With Tetralogy of Fallot. (PubMed)

Mechanism and Risk Factors for Death in Adults With Tetralogy of Fallot. One of the goals of lifelong care in adults with tetralogy of Fallot (TOF) is early identification and treatment of patients at high risk for adverse events. Clinical risk stratification tools are critical for achieving this goal. We reviewed the Mayo Adult Congenital Heart Disease database and identified 465 TOF patients (age 37 ± 14 years, men 223 [48%]) seen at Mayo Clinic Rochester between 1990 and 2017. The aim (...) was to determine the risk factors for death and/or heart transplant through a comprehensive analysis of 8 groups of variables (demographics, co-morbidities, medications, heart rhythm, echocardiography, cardiac magnetic resonance imaging, cardiac catheterization, and cardiopulmonary exercise test data) using univariable and multivariable Cox proportional hazard models. The end point of death and/or transplant occurred in 57 (12%) patients during a follow-up of 13.6 ± 8.2 years, yielding an event rate of 0.9

2019 American Journal of Cardiology

192. Management of Heart Failure  (3rd Edition)

% Fraction (HFpEF)17 4. Aetiology Heart failure is not a complete diagnosis. It is important to identify the underlying disease and the precipitating cause(s), if present. Although systolic and diastolic dysfunction are separate pathophysiological entities, they often share common aetiologies. The most common underlying causes of HF in adults are: • Coronary artery disease • Hypertension Slightly less common causes include: • Dilated cardiomyopathy-idiopathic, familial • Valvular heart disease • Diabetic (...) cardiomyopathy Other causes of HF include: • Congenital heart disease • Cor pulmonale • Pericardial disease: constrictive pericarditis, cardiac tamponade • Hypertrophic cardiomyopathy • Viral myocarditis • Acute rheumatic fever • Toxic: Alcohol, adriamycin, cyclophosphamide • Endocrine and metabolic disorders: thyroid disease, acromegaly, phaechromocytoma • Collagen vascular disease: systemic lupus erythematosis, polymyositis, polyarteritis nodosa • Tachycardia induced cardiomyopathy • Miscellaneous - severe

2014 Ministry of Health, Malaysia

193. Acute heart failure with new-onset continuous murmur in a 26-year-old man. (PubMed)

diagnosis Aortic Rupture complications diagnosis Aortic Valve Insufficiency diagnosis etiology Diagnosis, Differential Echocardiography, Transesophageal methods Electrocardiography methods Heart Auscultation methods Heart Murmurs diagnosis etiology Humans Male Sinus of Valsalva abnormalities diagnostic imaging congenital heart disease echocardiography Competing interests: None declared. 2017 10 09 2017 11 23 2017 12 06 2018 1 13 6 0 2018 12 12 6 0 2018 1 13 6 0 ppublish 29326113 heartjnl-2017-312506 (...) of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Lin Ting-Wei TW Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. eng Case Reports Journal Article Research Support, Non-U.S. Gov't Video-Audio Media 2018 01 11 England Heart 9602087 1355-6037 AIM IM Adult Aortic Aneurysm congenital

2018 Heart

194. Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)

: Concurrent diagnosis of an acute coronary syndrome defined as typical chest pain in addition to a troponin rise above the 99th percentile and/or electrocardiographic changes suggestive of cardiac ischemia History of congenital heart disease requiring surgical correction History of a cardiac transplantation and/or ventricular assist device Systolic blood pressure <90 mmHg or mean arterial pressure <65 mmHg at the moment of admission Expected use of intravenous inotropes, vasopressors or nitroprusside (...) , there is not a lot of scientific data available regarding the optimal doses of these diuretic medications. In addition, it is observed that a lot of people, treated with these drugs, are being readmitted to the hospital due to a new episode of heart failure. The hypothesis of this study is that the volume overload could be better treated when patients receive a combination of different types of diuretics. Additionally, the total dose of the administrated diuretics might be lower this way. Condition or disease

2018 Clinical Trials

195. Management of Incidental Findings Detected During Research Imaging

Routine specialist radiologist report Additional clinical scans & routine radiology report Additional clinical scans & routine specialist radiologist report PI imaging only adults PI imaging children Non-radiologist PI Radiologist PI Non-medical PI Medical PI Total PI (ideal practice) Total PI Principal investigator reporting strategies Figure 1. Research image reporting strategy. Bar charts demonstrating principal investigator (PI) reporting strategies (current practice unless shown otherwise (...) Management of Incidental Findings Detected During Research Imaging Management of Incidental Findings Detected During Research Imaging A report by Representatives of Research Imaging Centres, Professional Societies, Regulatory Bodies, Funding Organisations, Royal Colleges involved in research imaging and Patient Organisations, in the UK In collaboration with:Participating Imaging Research Centres n Aberdeen Biomedical Imaging Centre n Aston Brain Centre n Bangor University Imaging Centre n

2011 Royal College of Radiologists

196. Liver Function Measured by HepQuant-SHUNT in the Prediction of Outcomes in Patients With Heart Disease

about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 70 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Written informed consent obtained prior to any study-specific assessments. Liver disease secondary to congenital heart disease (...) transplantation, improvement of liver function post revision), and thus can be used for prognosis in this condition, either alone or in conjunction with other clinical, physiological, and laboratory prognostic scores, thereby giving clinical guidance concerning the need for heart transplantation and simultaneous liver transplantation.. Primary Aim To assess the relationship between HepQuant testing results and clinical outcomes in patients with liver disease secondary to congenital heart disease (CHD

2015 Clinical Trials

197. Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease

Heart Diseases Cardiovascular Diseases Anemia, Hemolytic, Congenital Anemia, Hemolytic Anemia Hematologic Diseases Hemoglobinopathies Genetic Diseases, Inborn (...) Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2014 Clinical Trials

198. Developing a Novel Imaging Biomarker in the Differential Diagnosis of Parkinson's Disease and Parkinsonism by 18F-DTBZ PET

values, and/or clinically significant or unstable medical or psychiatric illness. i. Clinically significant hepatic, renal, pulmonary, metabolic, or endocrine disturbances. ii. Current clinically significant cardiovascular disease. (cardiac surgery or myocardial infarction within the last 6 months; unstable angina; decompensated congestive heart failure; significant cardiac arrhythmia; congenital heart disease. History of drug or alcohol abuse within the last year, or prior prolonged history of abuse (...) Developing a Novel Imaging Biomarker in the Differential Diagnosis of Parkinson's Disease and Parkinsonism by 18F-DTBZ PET Developing a Novel Imaging Biomarker in the Differential Diagnosis of Parkinson's Disease and Parkinsonism - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2014 Clinical Trials

199. Acute and Chronic Heart Failure

. . . . . . . . . . . . . . . . . . .1831 12.7.1 Patients with a concomitant acute coronary syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1831 12.7.2 Isolated right ventricular failure . . . . . . . . . . . . .1832 12.7.3 Acute heart failure with ‘cardiorenal syndrome’ . .1832 12.7.4 Perioperative acute heart failure . . . . . . . . . . . .1832 12.7.5 Peripartum cardiomyopathy . . . . . . . . . . . . . . .1832 12.7.6 Adult congenital heart disease . . . . . . . . . . . . . .1832 13. Coronary revascularization (...) ACE angiotensin-converting enzyme ACHD adult congenital heart disease AF atrial ?brillation AF-CHF Atrial Fibrillation and Congestive Heart Failure AHF acute heart failure AIRE Acute Infarction Ramipril Ef?cacy ARB angiotensin receptor blocker ARR absolute risk reduction ATLAS Assessment of Treatment with Lisinopril And Survival AV atrioventricular AVP arginine vasopressin BEAUTIFUL MorBidity-mortality EvAlUaTion of the I f inhibi- tor ivabradine in patients with coronary disease and left

2012 European Society of Cardiology

200. Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging

IPF PET imaging Idiopathic Pulmonary Fibrosis Safety Pharmacokinetics Double-blind Additional relevant MeSH terms: Layout table for MeSH terms Fibrosis Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis Idiopathic Interstitial Pneumonias Pathologic Processes Lung Diseases Respiratory Tract Diseases Lung Diseases, Interstitial (...) Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached

2017 Clinical Trials

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