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Congenital Heart Disease Imaging in Adults

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181. Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)

: Concurrent diagnosis of an acute coronary syndrome defined as typical chest pain in addition to a troponin rise above the 99th percentile and/or electrocardiographic changes suggestive of cardiac ischemia History of congenital heart disease requiring surgical correction History of a cardiac transplantation and/or ventricular assist device Systolic blood pressure <90 mmHg or mean arterial pressure <65 mmHg at the moment of admission Expected use of intravenous inotropes, vasopressors or nitroprusside (...) , there is not a lot of scientific data available regarding the optimal doses of these diuretic medications. In addition, it is observed that a lot of people, treated with these drugs, are being readmitted to the hospital due to a new episode of heart failure. The hypothesis of this study is that the volume overload could be better treated when patients receive a combination of different types of diuretics. Additionally, the total dose of the administrated diuretics might be lower this way. Condition or disease

2018 Clinical Trials

182. Liver Function Measured by HepQuant-SHUNT in the Prediction of Outcomes in Patients With Heart Disease

about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 70 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Written informed consent obtained prior to any study-specific assessments. Liver disease secondary to congenital heart disease (...) transplantation, improvement of liver function post revision), and thus can be used for prognosis in this condition, either alone or in conjunction with other clinical, physiological, and laboratory prognostic scores, thereby giving clinical guidance concerning the need for heart transplantation and simultaneous liver transplantation.. Primary Aim To assess the relationship between HepQuant testing results and clinical outcomes in patients with liver disease secondary to congenital heart disease (CHD

2015 Clinical Trials

183. Acute and Chronic Heart Failure

. . . . . . . . . . . . . . . . . . .1831 12.7.1 Patients with a concomitant acute coronary syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1831 12.7.2 Isolated right ventricular failure . . . . . . . . . . . . .1832 12.7.3 Acute heart failure with ‘cardiorenal syndrome’ . .1832 12.7.4 Perioperative acute heart failure . . . . . . . . . . . .1832 12.7.5 Peripartum cardiomyopathy . . . . . . . . . . . . . . .1832 12.7.6 Adult congenital heart disease . . . . . . . . . . . . . .1832 13. Coronary revascularization (...) ACE angiotensin-converting enzyme ACHD adult congenital heart disease AF atrial ?brillation AF-CHF Atrial Fibrillation and Congestive Heart Failure AHF acute heart failure AIRE Acute Infarction Ramipril Ef?cacy ARB angiotensin receptor blocker ARR absolute risk reduction ATLAS Assessment of Treatment with Lisinopril And Survival AV atrioventricular AVP arginine vasopressin BEAUTIFUL MorBidity-mortality EvAlUaTion of the I f inhibi- tor ivabradine in patients with coronary disease and left

2012 European Society of Cardiology

184. Management of Incidental Findings Detected During Research Imaging

Routine specialist radiologist report Additional clinical scans & routine radiology report Additional clinical scans & routine specialist radiologist report PI imaging only adults PI imaging children Non-radiologist PI Radiologist PI Non-medical PI Medical PI Total PI (ideal practice) Total PI Principal investigator reporting strategies Figure 1. Research image reporting strategy. Bar charts demonstrating principal investigator (PI) reporting strategies (current practice unless shown otherwise (...) Management of Incidental Findings Detected During Research Imaging Management of Incidental Findings Detected During Research Imaging A report by Representatives of Research Imaging Centres, Professional Societies, Regulatory Bodies, Funding Organisations, Royal Colleges involved in research imaging and Patient Organisations, in the UK In collaboration with:Participating Imaging Research Centres n Aberdeen Biomedical Imaging Centre n Aston Brain Centre n Bangor University Imaging Centre n

2011 Royal College of Radiologists

185. 2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia

Management: Recommendations e542 Junctional Tachycardia e544 8.1. Acute Treatment: Recommendations e544 8.2. Ongoing Management: Recommendations e545 Special Populations e545 9.1. Pediatrics e545 9.2. Patients With Adult Congenital Heart Disease e549 9.2.1. Clinical Features e549 9.2.2. Acute Treatment: Recommendations e550 9.2.3. Ongoing Management: Recommendations e551 9.3. Pregnancy e553 9.3.1. Acute Treatment: Recommendations e553 9.3.2. Ongoing Management: Recommendations e554 9.4. SVT in Older (...) -based therapy ACC/AHA/HRS 2012 Atrial fibrillation CCS 2014 2011 Hypertrophic cardiomyopathy ACC/AHA 2011 Secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease AHA/ACC 2011 Adult congenital heart disease ACC/AHA 2008 Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VII) NHLBI 2003 Statements Catheter ablation in children and patients with congenital heart

2015 American Heart Association

186. Pressure Relief for Children, Adolescents and Young Adults with a Traumatic Spinal Cord Injury ? Comparison of ?Push-Up? Pressure Relief and Wheelchair Tilt Pressure Relief to Reduce the Incidence of Pressure Ulcer Formation

of 322 patients on bedrest for at least 24 hours without pre-existing pressure ulcers or congenital heart disease were enrolled from three pediatric intensive care units(PICU). The Braden Q score and skin assessment were independently rated and data collectors were blind to the other measures. Patients were observed up to 3 times per week for2 weeks and then once a week until PICU discharge for a median of 2 observations reflecting 887 skin assessments. Eighty-six patients (27%) developed 199 (...) be found in the Supporting Information section. Target Population for the Recommendation Children, adolescents and young adults with spinal cord injury age 5 to 21 years Inclusions ? Diagnosis of spinal cord injury of traumatic onset Exclusions ? Diagnosis of spinal tumors ? Congenital spinal cord injury including but not limited to Myelomeningocele ? Cerebral Palsy ? Scoliosis ? Tethered Cord Recommendation There is insufficient evidence and a lack of consensus to make a recommendation on preferred

2015 Cincinnati Children's Hospital Medical Center

187. European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults

Publication Date: Aug 2015 Copyright: © 2015 European Society of Endocrinology 2015 Free access Hypoparathyroidism (HypoPT) is a rare (orphan) endocrine disease with low calcium and inappropriately low (insufficient) circulating parathyroid hormone levels, most often in adults secondary to thyroid surgery. Standard treatment is activated vitamin D analogues and calcium supplementation and not replacement of the lacking hormone, as in other hormonal deficiency states. The purpose of this guideline (...) is to provide clinicians with guidance on the treatment and monitoring of chronic HypoPT in adults who do not have end-stage renal disease. We intend to draft a practical guideline, focusing on operationalized recommendations deemed to be useful in the daily management of patients. This guideline was developed and solely sponsored by The European Society of Endocrinology , supported by CBO (Dutch Institute for Health Care Improvement) and based on the Grading of Recommendations Assessment, Development

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2015 European Society of Endocrinology

188. Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease

Heart Diseases Cardiovascular Diseases Anemia, Hemolytic, Congenital Anemia, Hemolytic Anemia Hematologic Diseases Hemoglobinopathies Genetic Diseases, Inborn (...) Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2014 Clinical Trials

189. Developing a Novel Imaging Biomarker in the Differential Diagnosis of Parkinson's Disease and Parkinsonism by 18F-DTBZ PET

values, and/or clinically significant or unstable medical or psychiatric illness. i. Clinically significant hepatic, renal, pulmonary, metabolic, or endocrine disturbances. ii. Current clinically significant cardiovascular disease. (cardiac surgery or myocardial infarction within the last 6 months; unstable angina; decompensated congestive heart failure; significant cardiac arrhythmia; congenital heart disease. History of drug or alcohol abuse within the last year, or prior prolonged history of abuse (...) Developing a Novel Imaging Biomarker in the Differential Diagnosis of Parkinson's Disease and Parkinsonism by 18F-DTBZ PET Developing a Novel Imaging Biomarker in the Differential Diagnosis of Parkinson's Disease and Parkinsonism - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2014 Clinical Trials

190. Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging

IPF PET imaging Idiopathic Pulmonary Fibrosis Safety Pharmacokinetics Double-blind Additional relevant MeSH terms: Layout table for MeSH terms Fibrosis Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis Idiopathic Interstitial Pneumonias Pathologic Processes Lung Diseases Respiratory Tract Diseases Lung Diseases, Interstitial (...) Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached

2017 Clinical Trials

191. Diagnosis, imaging and clinical management of aortic coarctation. (PubMed)

Diagnosis, imaging and clinical management of aortic coarctation. Coarctation of the aorta (CoA ) is a well-known congenital heart disease (CHD) , which is often associated with several other cardiac and vascular anomalies, such as bicuspid aortic valve (BAV), ventricular septal defect, patent ductus arteriosus and aortic arch hypoplasia. Despite echocardiographic screening, prenatal diagnosis of C o A remains difficult. Most patients with CoA present in infancy with absent, delayed or reduced (...) follow-up of the left ventricular function, valvular function, blood pressure and the anatomy of the heart and the aorta are , therefore, critical in the management of CoA. This review provides an overview of the current state-of-the-art clinical diagnosis, diagnostic imaging algori thms, treatment and follow-up of patients with CoA.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise

2017 Heart

192. Contrast-Enhanced Subharmonic Ultrasound Imaging in Improving Characterization of Adnexal Masses in Patients Undergoing Surgery

ultrasound imaging works in improving the characterization of adnexal masses in patients undergoing surgery. Contrast-enhanced subharmonic ultrasound imaging uses high-frequency sound waves to produce images of internal organs and when combined with an ultrasound agent such as perflutren lipid microspheres, may help improve imaging and management of adnexal masses. Condition or disease Intervention/treatment Phase Adnexal Mass Drug: Perflutren Lipid Microspheres Procedure: Contrast-Enhanced Subharmonic (...) with congenital heart defects Patients with severe emphysema, pulmonary vasculitis, or a history of pulmonary emboli Patients with respiratory distress syndrome Patients with thrombosis within the splenic vein Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number

2017 Clinical Trials

193. High Resolution Micro OCT Imaging

System Diseases Lung Diseases Respiratory Tract Diseases Genetic Diseases, Inborn Infant, Newborn, Diseases Movement Disorders Central Nervous System Diseases Nervous System Diseases Neurologic Manifestations Signs and Symptoms Otorhinolaryngologic Diseases Ciliopathies Abnormalities, Multiple Congenital Abnormalities Bronchiectasis Bronchial Diseases Respiratory System Abnormalities Dextrocardia Heart Defects, Congenital Cardiovascular Abnormalities Cardiovascular Diseases Heart Diseases Situs (...) by (Responsible Party): Steven M Rowe, University of Alabama at Birmingham Study Details Study Description Go to Brief Summary: The purpose of this study is to learn about using the imaging to make images of the lungs and nose with the long-term goal of the research leading to potential treatments and new therapies for patients with cystic fibrosis. Condition or disease Cystic Fibrosis COPD PCD - Primary Ciliary Dyskinesia Detailed Description: Lung Disease is the predominate cause of morbidity and mortality

2017 Clinical Trials

194. Fontan Imaging Biomarkers (FIB) Study

Hearts of Hope Foundation Information provided by (Responsible Party): Rahul Rathod, Boston Children’s Hospital Study Details Study Description Go to Brief Summary: The goal of the Fontan Imaging Biomarkers (FIB) study is to identify the associations of blood and urine biomarkers to imaging parameters of ventricular mechanics. Condition or disease Single-ventricle Congenital Heart Disease Detailed Description: This study has the following research questions: What is the reproducibility of ventricular (...) : No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Rahul Rathod, Boston Children’s Hospital: biomarkers Fontan operation Single ventricle congenital heart disease Additional relevant MeSH terms: Layout table for MeSH terms Heart Diseases Heart Defects, Congenital Cardiovascular Diseases Cardiovascular Abnormalities Congenital Abnormalities

2017 Clinical Trials

195. Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System

examinations on two different MRI scan-ners (investigational low SAR CMR and conventional 1.5T CMR), some without- and some with administration of intravenous GBCA. Group B Group B includes 100 adult subjects of both sexes with known stable cardiovascular disease including adults with stable coronary artery disease after myocardial infarction; adults with heart failure and reduced left ventricular systolic function; adults with pulmonary artery hypertension; adults with congenital heart disease including (...) as a magnetic resonance imagining (MRI) scanner that uses strong magnetic fields, radio waves and the like to create images of the organs in the body. It uses lower energy levels than other MRI scanners. This may help scan people with metal devices in their body, or in invasive heart procedures using metal tools. Objective: To test a new MRI scanner and software changes to create better pictures. Eligibility: People with disease and healthy volunteers, ages 18 and older. Design: Participants

2017 Clinical Trials

196. Liver Disease and Pregnancy

of pregnant patient A pregnant patient presenting with abnormal liver tests should undergo standard workup as with any non-pregnant individual (strong recommendation, very low level of evidence). Imaging in pregnancy Ultrasound is safe and the preferred imaging modality used in assessment of abnormal liver tests suggestive of biliary tract disease (strong recommenda- tion, low level of evidence). Magnetic resonance imaging without gadolinium can be used in the second and third trimester (conditional (...) history, physical exam, and standard serological workup should be performed as indicated by the clinical presentation. Initial evaluation of these patients can be cate gorized into two general groups: (i) pre-existing and coin- cidental, not related to pregnancy, or (ii) related to the pregnancy itself. IMAGING Recommendations: 2. Ultrasound is safe and the preferred imaging modality used in assessment of abnormal liver tests suggestive of biliary tract disease (strong recommendation, low level

2016 American College of Gastroenterology

197. Chronic Chest Pain - High Probability of Coronary Artery Disease

/stenting, or surgery. Third, imaging is also necessary to determine the long-term prognosis and likely benefit from various therapeutic options by evaluating ventricular function, diastolic relaxation, and end-systolic volume. Imaging studies are also required to demonstrate abnormalities (eg, congenital or acquired coronary anomalies, severe left ventricular [LV] hypertrophy) that can produce angina in the absence of symptomatic coronary obstructive disease due to atherosclerosis. Clinical risk (...) ), cardiac magnetic resonance imaging (MRI), and cardiac multidetector computed tomography (MDCT) have all been more recently shown to be valuable in the evaluation of ischemic heart disease. In those patients who do not present with signs classic for angina pectoris or in those patients who do not respond as expected to standard management, the exclusion of noncardiac causes of chronic chest pain requires the use of additional studies (eg, esophagography, upper gastrointestinal series, and biliary

2016 American College of Radiology

198. Cerebrovascular Disease

Disease Variant 3: New focal neurologic defect, fixed or worsening. Less than 6 hours. Suspected stroke. Radiologic Procedure Rating Comments RRL* CT head without IV contrast 9 Parenchymal brain imaging and CT or MR vascular imaging of the head and neck should be considered. Noncontrast head CT is often obtained first to assess for hemorrhage or large infarct. MRI is more sensitive than CT for acute infarct. ??? MRI head without IV contrast 8 Parenchymal brain imaging and CT or MR vascular imaging (...) O CT head with IV contrast 3 ??? Arteriography cervicocerebral 2 ??? MRA neck without IV contrast 2 O MRA neck without and with IV contrast 2 O CTA neck with IV contrast 2 ??? Rating Scale: 1,2,3 Usually not appropriate; 4,5,6 May be appropriate; 7,8,9 Usually appropriate *Relative Radiation Level ACR Appropriateness Criteria ® 6 Cerebrovascular Disease Variant 7: Proven SAH by lumbar puncture or imaging. Radiologic Procedure Rating Comments RRL* Arteriography cervicocerebral 9 Catheter

2016 American College of Radiology

199. Diagnosis and Treatment of Adult Isthmic Spondylolisthesis

Ion /Gu Idel Ine Methodolo Gy Diagnosis and Treatment of Adult Isthmic Spondylolisthesis | NASS Clinical Guidelines NASS Evidence-Based Clinical Guidelines Committee D. Scott Kreiner, MD Committee Co- Chair and Natural History Section Chair Jamie Baisden, MD Diagnosis/Imaging Section Chair Daniel Mazanec, MD Medical/Interventional Treatment Section Chair Rakesh Patel, MD Surgical Treatment Section Chair Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care Diagnosis and Treatment (...) ? Spondylolisthesis occurs in 40% to 66% of patients with bilateral spondylolysis. Spondylolisthesis is unlikely to occur in patients with unilateral spondylolysis. Grade of Recommendation: B Diagnosis and Imaging What are the most appropriate physical examination findings consistent with the diagnosis of isthmic spondylolisthesis in adult patients? There is insufficient evidence to make a recommendation for or against the use of palpation in the physical exam diagnosis of adult patients with isthmic

2014 North American Spine Society

200. Myocardial Perfusion Single-Photon Emission Tomography (SPET) and Positron Emission Tomography-Computed Tomography (PET-CT) Imaging for Congenitally Corrected Transposition of Great Arteries. (PubMed)

on the right ventricle involves an increased risk of coronary artery disease (CAD) and, as a long-term consequence, myocardial hypertrophy and gradual failure. This report describes the case of an adult patient affected by ccTGA who was referred for an episode of atypical chest pain while at rest. First-line diagnostic examinations were inconclusive. Myocardial perfusion single-photon emission tomography (SPET) was performed to exclude CAD, but the congenital abnormalities of the patient's heart made (...) Myocardial Perfusion Single-Photon Emission Tomography (SPET) and Positron Emission Tomography-Computed Tomography (PET-CT) Imaging for Congenitally Corrected Transposition of Great Arteries. Congenitally corrected transposition of great arteries (ccTGA) consists of both atrioventricular and ventriculo-arterial discordance. In patients with ccTGA, the pulmonary artery arises from the left ventricle, whereas the aorta arises from the right ventricle. The burden of the systemic blood pressure

2012 Pediatric Cardiology

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