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Congenital Heart Disease Imaging in Adults

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181. SCAI/HFSA Clinical Expert Consensus Document on the Use of Invasive Hemodynamics for the Diagnosis and Management of Cardiovascular Disease

interpreting accurate hemodynamic data obtained in the cardiac catheterization laboratory. Valvular Heart Disease For patients with valvular heart disease, an invasive hemodynamic evaluation is recommended to resolve discrepancies between clinical findings and noninvasive imaging data when surgical or catheter‐based therapy is being considered. When a patient undergoes an invasive hemodynamic evaluation for valvular disease, a simultaneous study of multiple central cardiac chamber hemodynamics should (...) . Attention should be directed toward the relative rise in left and right atrial pressure (RAP) with exercise, because the ratio of RAP/PCWP with exercise can be highly informative in isolating which “side” of the heart and circulation is the predominantly diseased and has the least physiologic reserve. Congenital Heart Disease For most patients with shunt lesions, echocardiography performed by an experienced sonographer, with careful examination of the gradients and chamber morphology, is sufficient

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2017 Society for Cardiovascular Angiography and Interventions

182. AIM Clinical Appropriateness Guidelines for Genetic Testing for Hereditary Cardiac Disease

of symptoms. Dilated Cardiomyopathy Dilated cardiomyopathy (DCM) is characterized by enlargement of the left ventricle of the heart and systolic impairment, in the absence of abnormal loading conditions or coronary artery disease sufficient to cause global systolic dysfunction (Haas 2015). The symptoms of DCM are similar to heart failure including shortness of breath, chest pain/tightness, fainting episodes and cardiac arrhythmias. The most serious complication of DCM is sudden, irregular heart rhythms (...) cardiac conduction disease (i.e. first, second or third degree heart block) and/or family history of premature unexplained death. In addition, they state that genetic testing can be useful for patients with familial DCM to confirm diagnosis, to recognize those who are at highest risk of arrhythmia and syndromic PROPRIETARY Guidelines developed by, and used with permission from, Informed Medical Decisions, Inc. © 2017 Informed Medical Decisions, Inc. All Rights Reserved. 7 features, to facilitate

2017 AIM Specialty Health

183. Dual-Source Computed Tomography Evaluation of Children with Congenital Pulmonary Valve Stenosis (PubMed)

Dual-Source Computed Tomography Evaluation of Children with Congenital Pulmonary Valve Stenosis Despite dual-source computed tomography (DSCT) technology has been performed well on adults or infants with heart disease, specific knowledge about children with congenital pulmonary valve stenosis (PS) remained to be established.This original research aimed to establish a professional approach of DSCT performing technology on children and to assess the image quality performed by DSCT to establish (...) a diagnostic evaluation for children with PS.Ninety-eight children with congenital PS referred to affiliated hospital of Jining medical college were recruited from October 2013 to March 2015. Participants were divided into four groups according to different ages (0 - 1, 1 - 3, 3 - 7, 7 - 14), or three groups according to different heart rates (< 90, 90 - 110, > 110). Image quality of pulmonary valves was assessed based on a four-point grading scale (1 - 4 points). Those cases achieving a score of ≥ 3

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2016 Iranian Journal of Radiology

184. Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging

: Diagnostic Official Title: An Adaptive, Open-Label Study to Evaluate the Biodistribution of 89Zirconium-labelled GSK2398852 in the Heart and Other Organs of Patients With Transthyretin Cardiomyopathy (ATTR-CM) Using Positron Emission Tomography (PET) Imaging Actual Study Start Date : April 6, 2018 Actual Primary Completion Date : July 20, 2018 Actual Study Completion Date : July 20, 2018 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go (...) as solution containing 10 mg 89Zr-GSK2398852 for Infusion. Subjects will be administered 37 (Megabecquerel) MBq radioactive dose of 89Zr-GSK2398852 by the IV route at each dosing session. Outcome Measures Go to Primary Outcome Measures : Standardized Uptake Values (SUV) in focal anatomical regions of the heart following 80-200 milligrams (mg) dose of anti-SAP mAb [ Time Frame: Up to Day 6 ] PET images will be visually reviewed to assess the radioactivity distribution. SUV is the measured radioactivity

2018 Clinical Trials

185. Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging

Posted : March 26, 2019 Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Information provided by (Responsible Party): National Institutes of Health Clinical Center (CC) ( National Heart, Lung, and Blood Institute (NHLBI) ) Study Details Study Description Go to Brief Summary: Background: Painful vasoocclusive crisis (VOC) occurs in people with sickle cell disease (SCD). People with VOC have many visits to the hospital. About 10 30 percent of these people will go on to develop acute chest (...) Sickle Cell Disease Acute Chest Syndrome Pulmonary Syndrome Pneumonia Additional relevant MeSH terms: Layout table for MeSH terms Syndrome Anemia, Sickle Cell Acute Chest Syndrome Disease Pathologic Processes Anemia, Hemolytic, Congenital Anemia, Hemolytic Anemia Hematologic Diseases Hemoglobinopathies Genetic Diseases, Inborn Lung Diseases Respiratory Tract Diseases Respiration Disorders

2018 Clinical Trials

186. Imaging by 4 DFlow in Patients With Tetralogy of Fallot

Flow CMR for the assessment of these parameters (ventricular volume, ventricular systolic function, and regurgitation of the pulmonary pathway). Condition or disease Intervention/treatment Phase Congenital Heart Disease Procedure: magnetic resonance imaging Not Applicable Detailed Description: Congenital heart disease, or corrected heart disease requires regular, specialized follow-up throughout the life of these patients. Among the recommended examinations, cardiac MRI is the reference (...) Chirurgical Marie Lannelongue: Congenital heart disease Tetralogy of Fallot Imaging by 4D Flow, Magnetic resonance imaging Prevention of ventricular dysfunction Additional relevant MeSH terms: Layout table for MeSH terms Heart Diseases Heart Defects, Congenital Tetralogy of Fallot Cardiovascular Diseases Cardiovascular Abnormalities Congenital Abnormalities

2018 Clinical Trials

187. Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging

or hypersensitive reaction to dexmedetomidine Organ dysfunction, and significant developmental delays or behavior problems Cardiac arrhythmia Known. acyanotic congenital heart disease or children after cardiac interventional procedures for follow-up examination Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study (...) Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2018 Clinical Trials

188. Interactive Guided Ultrasound Examinations Done by Non-experts of Ultrasound Imaging

informed consent. All volunteers should be affiliated to the French Social Security. All volunteers will be scheduled for a routine transthoracic echocardiography exam in the echocardiography laboratory at the investigation site as part of standard care. Exclusion Criteria: Subjects with congenital heart diseases (except bicuspid aortic valve) Pregnant women Adults lacking decisional capacity Adults placed under a legal protection regime (guardianship, curatorship, judicial protection) Adults (...) Healthcare Information provided by (Responsible Party): Philips Healthcare Study Details Study Description Go to Brief Summary: This prospective study is a pilot study for evaluating a guidance system that aims to facilitate high-quality echocardiographic acquisitions. Condition or disease Intervention/treatment Phase Cardiac Disease Heart Failure Cardiac Ischemia Device: TransThoracic Echocardiography imaging Not Applicable Detailed Description: The primary objective of this study is to assess

2018 Clinical Trials

189. Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary Hypertension

to develop a multi-scale computational model of Pulmonary Hypertension, this clinical model will be calibrated using longitudinal, retrospectively and prospectively acquired human clinical data. Condition or disease Intervention/treatment Pulmonary Hypertension Congenital Heart Disease Pediatric Congenital Heart Disease Procedure: cardiac catheterization Radiation: Cardiac MRI Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 50 participants (...) and Vascular Surgery, University of Michigan ClinicalTrials.gov Identifier: Other Study ID Numbers: HUM00117706 First Posted: June 21, 2018 Last Update Posted: June 21, 2018 Last Verified: June 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Hypertension Heart Diseases Hypertension, Pulmonary Heart Defects, Congenital Vascular Diseases Cardiovascular

2018 Clinical Trials

190. Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot. (PubMed)

Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot. Congestive hepatopathy and hepatocellular carcinoma is a serious complication after Fontan procedure. Liver fibrosis due to hepatic congestion could occur also in adult patients after repair of tetralogy of Fallot (rTOF). However, the incidence and severity remain unclear.A total of 111 patients with adult congenital heart disease between 2009 and 2016 were enrolled (...) pathological evidence of moderate and severe (F2 and F3) liver fibrosis and one had combined hepatocellular and cholangiocarcinoma.We first demonstrated elevated liver fibrosis markers in adult patients with rTOF. These levels may help to predict the progressive liver disease as well as consider the timing of pulmonary valve replacement.Copyright © 2019 Elsevier B.V. All rights reserved.

2019 International journal of cardiology

191. Mechanism and Risk Factors for Death in Adults With Tetralogy of Fallot. (PubMed)

Mechanism and Risk Factors for Death in Adults With Tetralogy of Fallot. One of the goals of lifelong care in adults with tetralogy of Fallot (TOF) is early identification and treatment of patients at high risk for adverse events. Clinical risk stratification tools are critical for achieving this goal. We reviewed the Mayo Adult Congenital Heart Disease database and identified 465 TOF patients (age 37 ± 14 years, men 223 [48%]) seen at Mayo Clinic Rochester between 1990 and 2017. The aim (...) was to determine the risk factors for death and/or heart transplant through a comprehensive analysis of 8 groups of variables (demographics, co-morbidities, medications, heart rhythm, echocardiography, cardiac magnetic resonance imaging, cardiac catheterization, and cardiopulmonary exercise test data) using univariable and multivariable Cox proportional hazard models. The end point of death and/or transplant occurred in 57 (12%) patients during a follow-up of 13.6 ± 8.2 years, yielding an event rate of 0.9

2019 American Journal of Cardiology

192. Management of Heart Failure  (3rd Edition)

% Fraction (HFpEF)17 4. Aetiology Heart failure is not a complete diagnosis. It is important to identify the underlying disease and the precipitating cause(s), if present. Although systolic and diastolic dysfunction are separate pathophysiological entities, they often share common aetiologies. The most common underlying causes of HF in adults are: • Coronary artery disease • Hypertension Slightly less common causes include: • Dilated cardiomyopathy-idiopathic, familial • Valvular heart disease • Diabetic (...) cardiomyopathy Other causes of HF include: • Congenital heart disease • Cor pulmonale • Pericardial disease: constrictive pericarditis, cardiac tamponade • Hypertrophic cardiomyopathy • Viral myocarditis • Acute rheumatic fever • Toxic: Alcohol, adriamycin, cyclophosphamide • Endocrine and metabolic disorders: thyroid disease, acromegaly, phaechromocytoma • Collagen vascular disease: systemic lupus erythematosis, polymyositis, polyarteritis nodosa • Tachycardia induced cardiomyopathy • Miscellaneous - severe

2014 Ministry of Health, Malaysia

193. Acute heart failure with new-onset continuous murmur in a 26-year-old man. (PubMed)

diagnosis Aortic Rupture complications diagnosis Aortic Valve Insufficiency diagnosis etiology Diagnosis, Differential Echocardiography, Transesophageal methods Electrocardiography methods Heart Auscultation methods Heart Murmurs diagnosis etiology Humans Male Sinus of Valsalva abnormalities diagnostic imaging congenital heart disease echocardiography Competing interests: None declared. 2017 10 09 2017 11 23 2017 12 06 2018 1 13 6 0 2018 12 12 6 0 2018 1 13 6 0 ppublish 29326113 heartjnl-2017-312506 (...) of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Lin Ting-Wei TW Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. eng Case Reports Journal Article Research Support, Non-U.S. Gov't Video-Audio Media 2018 01 11 England Heart 9602087 1355-6037 AIM IM Adult Aortic Aneurysm congenital

2018 Heart

194. Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)

: Concurrent diagnosis of an acute coronary syndrome defined as typical chest pain in addition to a troponin rise above the 99th percentile and/or electrocardiographic changes suggestive of cardiac ischemia History of congenital heart disease requiring surgical correction History of a cardiac transplantation and/or ventricular assist device Systolic blood pressure <90 mmHg or mean arterial pressure <65 mmHg at the moment of admission Expected use of intravenous inotropes, vasopressors or nitroprusside (...) , there is not a lot of scientific data available regarding the optimal doses of these diuretic medications. In addition, it is observed that a lot of people, treated with these drugs, are being readmitted to the hospital due to a new episode of heart failure. The hypothesis of this study is that the volume overload could be better treated when patients receive a combination of different types of diuretics. Additionally, the total dose of the administrated diuretics might be lower this way. Condition or disease

2018 Clinical Trials

195. Liver Function Measured by HepQuant-SHUNT in the Prediction of Outcomes in Patients With Heart Disease

about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 70 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Written informed consent obtained prior to any study-specific assessments. Liver disease secondary to congenital heart disease (...) transplantation, improvement of liver function post revision), and thus can be used for prognosis in this condition, either alone or in conjunction with other clinical, physiological, and laboratory prognostic scores, thereby giving clinical guidance concerning the need for heart transplantation and simultaneous liver transplantation.. Primary Aim To assess the relationship between HepQuant testing results and clinical outcomes in patients with liver disease secondary to congenital heart disease (CHD

2015 Clinical Trials

196. Acute and Chronic Heart Failure

. . . . . . . . . . . . . . . . . . .1831 12.7.1 Patients with a concomitant acute coronary syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1831 12.7.2 Isolated right ventricular failure . . . . . . . . . . . . .1832 12.7.3 Acute heart failure with ‘cardiorenal syndrome’ . .1832 12.7.4 Perioperative acute heart failure . . . . . . . . . . . .1832 12.7.5 Peripartum cardiomyopathy . . . . . . . . . . . . . . .1832 12.7.6 Adult congenital heart disease . . . . . . . . . . . . . .1832 13. Coronary revascularization (...) ACE angiotensin-converting enzyme ACHD adult congenital heart disease AF atrial ?brillation AF-CHF Atrial Fibrillation and Congestive Heart Failure AHF acute heart failure AIRE Acute Infarction Ramipril Ef?cacy ARB angiotensin receptor blocker ARR absolute risk reduction ATLAS Assessment of Treatment with Lisinopril And Survival AV atrioventricular AVP arginine vasopressin BEAUTIFUL MorBidity-mortality EvAlUaTion of the I f inhibi- tor ivabradine in patients with coronary disease and left

2012 European Society of Cardiology

197. Management of Incidental Findings Detected During Research Imaging

Routine specialist radiologist report Additional clinical scans & routine radiology report Additional clinical scans & routine specialist radiologist report PI imaging only adults PI imaging children Non-radiologist PI Radiologist PI Non-medical PI Medical PI Total PI (ideal practice) Total PI Principal investigator reporting strategies Figure 1. Research image reporting strategy. Bar charts demonstrating principal investigator (PI) reporting strategies (current practice unless shown otherwise (...) Management of Incidental Findings Detected During Research Imaging Management of Incidental Findings Detected During Research Imaging A report by Representatives of Research Imaging Centres, Professional Societies, Regulatory Bodies, Funding Organisations, Royal Colleges involved in research imaging and Patient Organisations, in the UK In collaboration with:Participating Imaging Research Centres n Aberdeen Biomedical Imaging Centre n Aston Brain Centre n Bangor University Imaging Centre n

2011 Royal College of Radiologists

198. 2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia

Management: Recommendations e542 Junctional Tachycardia e544 8.1. Acute Treatment: Recommendations e544 8.2. Ongoing Management: Recommendations e545 Special Populations e545 9.1. Pediatrics e545 9.2. Patients With Adult Congenital Heart Disease e549 9.2.1. Clinical Features e549 9.2.2. Acute Treatment: Recommendations e550 9.2.3. Ongoing Management: Recommendations e551 9.3. Pregnancy e553 9.3.1. Acute Treatment: Recommendations e553 9.3.2. Ongoing Management: Recommendations e554 9.4. SVT in Older (...) -based therapy ACC/AHA/HRS 2012 Atrial fibrillation CCS 2014 2011 Hypertrophic cardiomyopathy ACC/AHA 2011 Secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease AHA/ACC 2011 Adult congenital heart disease ACC/AHA 2008 Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VII) NHLBI 2003 Statements Catheter ablation in children and patients with congenital heart

2015 American Heart Association

199. Pressure Relief for Children, Adolescents and Young Adults with a Traumatic Spinal Cord Injury ? Comparison of ?Push-Up? Pressure Relief and Wheelchair Tilt Pressure Relief to Reduce the Incidence of Pressure Ulcer Formation

of 322 patients on bedrest for at least 24 hours without pre-existing pressure ulcers or congenital heart disease were enrolled from three pediatric intensive care units(PICU). The Braden Q score and skin assessment were independently rated and data collectors were blind to the other measures. Patients were observed up to 3 times per week for2 weeks and then once a week until PICU discharge for a median of 2 observations reflecting 887 skin assessments. Eighty-six patients (27%) developed 199 (...) be found in the Supporting Information section. Target Population for the Recommendation Children, adolescents and young adults with spinal cord injury age 5 to 21 years Inclusions ? Diagnosis of spinal cord injury of traumatic onset Exclusions ? Diagnosis of spinal tumors ? Congenital spinal cord injury including but not limited to Myelomeningocele ? Cerebral Palsy ? Scoliosis ? Tethered Cord Recommendation There is insufficient evidence and a lack of consensus to make a recommendation on preferred

2015 Cincinnati Children's Hospital Medical Center

200. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications

transesophageal echocardiography; and TTE, transthoracic echocardiography. Figure. An approach to the diagnostic use of echocardiography (echo). Rx indicates prescription; TEE, transesophageal echocardiography; and TTE, transthoracic echocardiography. *For example, a patient with fever and a previously known heart murmur and no other stigmata of infective endocarditis (IE). †High initial patient risks include prosthetic heart valves, many congenital heart diseases, previous endocarditis, new murmur, heart (...) of cookies. Free Access article Share on Jump to Free Access article Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications A Scientific Statement for Healthcare Professionals From the American Heart Association , MD, FAHA , MD , MD , MD, MHS , MD, MSc , PharmD, MPH , MD, PhD , DDS , MD, FAHA , MD , MD, FAHA , MD , MD , PhD, RN and MD, FAHA PhD, FAHA Larry M. Baddour , Walter R. Wilson , Arnold S. Bayer , Vance G. FowlerJr , Imad M. Tleyjeh , Michael J. Rybak

2015 American Heart Association

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