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141. Circumferential Three-Dimensional-Printed Tracheal Grafts: Research Model Feasibility and Early Results. (PubMed)

models of porcine subject tracheas were generated using preoperative computed tomography scans. Two designs were used to test graft customizability and the limits of the construction process. Designs I and II used 270-degree and 360-degree external polycaprolactone scaffolds, respectively, both encompassing a circumferential extracellular matrix collagen layer. The polycaprolactone scaffolds were made in a fused-deposition modeling 3D printer and customized to the recipient's anatomy. Design I

2017 Annals of Thoracic Surgery

142. Development of a Tailored Thyroid Gland Phantom for Fine-Needle Aspiration Cytology by Three-Dimensional Printing. (PubMed)

, and ultrasonographic (US) characteristics.A three-dimensional (3D) digital model of the human neck was reconstructed from computed tomography data of a subject. This model was used to create 3D-printed templates for various organs that require US visualization. The templates were injected with polymers that provided similar degrees of ultrasound permeability as the corresponding organs. For fabrication of each organ, the respective molds of organs, blood vessels, thyroid gland, and tumor were injected (...) . In the survey, all 45 participants replied that they found the phantom useful for FNAC training, and 30 medical students professed increased interest in thyroid diseases after using the phantom.We successfully fabricated a tailored thyroid gland phantom for transfixion practice. As most of the phantom parts are injected in molds fabricated using a 3D printer, they can be easily reproduced once the molds are fabricated. This phantom is expected to serve as an effective and fully tailored training model

2017 Journal of Surgical Education

143. Evaluation of Different Techniques for Filling Simulated C-shaped Canals of 3-dimensional Printed Resin Teeth. (PubMed)

Evaluation of Different Techniques for Filling Simulated C-shaped Canals of 3-dimensional Printed Resin Teeth. The purpose of this study was to compare the ability of different root canal filling methods on the C1 root canal anatomy using 3-dimensional (3D) printer technology.Mandibular molars were scanned with cone-beam computed tomographic (CBCT) imaging. A mandibular molar tooth with a C1 root canal configuration was selected according to images obtained from CBCT technology. The root canals (...) were shaped with ProTaper Universal rotary instruments (Dentsply Maillefer, Ballaigues, Switzerland) and hand files. After the root canal shaping procedure, the tooth was scanned with micro-computed tomographic imaging, and 80 replicas of the tooth were produced with a 3D printer. Replicas were assigned into 4 groups (n = 20) and were filled using one of the following techniques: a core carrier system (GuttaCore [GC]; Dentsply Tulsa Dental Specialties, Tulsa, OK), a continuous wave obturation

2017 Journal of Endodontics

144. Accuracy of printed dental models made with 2 prototype technologies and different designs of model bases. (PubMed)

printers using different techniques: stereolithography and triple jetting technology (polyjet). The printed models were then scanned with a computed tomography scanner and a desktop laser scanner to create the respective digital models. Evaluation of the accuracy was done by measuring the dentitions with Ortho Analyzer software (3Shape, Copenhagen, Denmark) and by model superimposition with Geomagic Qualify software (3D Systems, Rock Hill, SC). An observer measured the distances twice, with an interval (...) of 2 weeks. The accuracy of the printed models was statistically evaluated by the mixed-effects regression model approach.The results showed that printed models made by the polyjet printer were accurate, regardless of the design of the model base. Printed models made with the stereolithography technique with the regular model base and the horseshoe-shaped base with a bar were accurate, but the transversal distances measured on the printed models with a horseshoe-shaped base were statistically

2017 American journal of orthodontics and dentofacial orthopedics

145. Creating an Optimal 3D Printed Model for Temporal Bone Dissection Training. (PubMed)

Creating an Optimal 3D Printed Model for Temporal Bone Dissection Training. Making a 3-dimensional (3D) temporal bone model is simple using a plaster powder bed and an inkjet printer. However, it is difficult to reproduce air-containing spaces and precise middle ear structures. The objective of this study was to overcome these problems and create a temporal bone model that would be useful both as a training tool and for preoperative simulation.Drainage holes were made to remove excess materials (...) from air-containing spaces, ossicle ligaments were manually changed to bony structures, and small and/or soft tissue structures were colored differently while designing the 3D models. The outcomes were evaluated by 3 procedures: macroscopic and endoscopic inspection of the model, comparison of computed tomography (CT) images of the model to the original CT, and assessment of tactile sensation and reproducibility by 20 surgeons performing surgery on the model.Macroscopic and endoscopic inspection

2017 Rhinology and Laryngology

146. Cardiac 3D Printing and its Future Directions. (PubMed)

Cardiac 3D Printing and its Future Directions. Three-dimensional (3D) printing is at the crossroads of printer and materials engineering, noninvasive diagnostic imaging, computer-aided design, and structural heart intervention. Cardiovascular applications of this technology development include the use of patient-specific 3D models for medical teaching, exploration of valve and vessel function, surgical and catheter-based procedural planning, and early work in designing and refining the latest

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2017 JACC. Cardiovascular imaging

147. Microguided Endodontics: Accuracy of a Miniaturized Technique for Apically Extended Access Cavity Preparation in Anterior Teeth. (PubMed)

. Preoperative surface and cone-beam computed tomography scans were matched by using the coDiagnostix software. Virtual planning was performed for the access cavities, and templates were used for guidance. The templates were produced by a three-dimensional printer. Two operators performed the access cavities. A postoperative cone-beam computed tomography scan was superimposed on the virtual plan, and the deviation was measured in 3 dimensions and angles. Descriptive statistical analyses were performed

2017 Journal of Endodontics

148. Value of 3D printing for the comprehension of surgical anatomy. (PubMed)

information.Fifteen patients scheduled for laparoscopic splenectomy, nephrectomy, or pancreatectomy were selected and, for each, a full-size 3D virtual anatomical object was reconstructed from a contrast-enhanced MDCT (Multiple Detector Computed Tomography) and then prototyped using a 3D printer. After having carefully evaluated-in a random sequence-conventional contrast MDCT scans, virtual 3D reconstructions on a flat monitor, and 3D-printed models of the same anatomy for each selected case, thirty subjects

2017 Surgical endoscopy

149. A New Spinal Brace Design Concept for the Treatment of Adolescent Idiopathic Scoliosis

which can improve brace design. However, it is still quite time consuming to construct a brace. Although 3D printing technology has been proposed to construct a scoliosis brace, its effectiveness has not been validated. The goals of this study was to investigate if an effective and comfortable brace can be designed and fabricated by using ultrasound and computer-aided design and computer-aided manufacturing (CAD/CAM) technology, and be printed directly from a 3D printer with faster production, lower (...) or less than 1 year postmenarchal. The 50 subjects will be randomly assigned to 2 equally sized groups (n=25 in each group): group A conventional designed and manual fabricated braces and group B ultrasound and CAD/CAM scanner designed brace with printing by a 3D printer. Both groups: A brace monitor (2.5cm x 4.0cm x 1.5 cm and 8g) developed from our group will be installed into all braces for both study groups. It will monitor patients' compliance which includes how much time they use their braces

2017 Clinical Trials

150. Preoperative planning and tracheal stent design in thoracic surgery: a primer for the 2017 Radiological Society of North America (RSNA) hands-on course in 3D printing (PubMed)

superior sulcus tumor. Furthermore, patient-specific device creation is demonstrated using dedicated computer-aided design software. Relevant anatomy for these tasks is obtained from CT Digital Imaging and Communications in Medicine images, leading to the generation of 3D printable files and delivery of these files to a 3D printer. (...) Preoperative planning and tracheal stent design in thoracic surgery: a primer for the 2017 Radiological Society of North America (RSNA) hands-on course in 3D printing In this work, we provide specific clinical examples to demonstrate basic practical techniques involved in image segmentation, computer-aided design, and 3D printing. A step-by-step approach using United States Food and Drug Administration cleared software is provided to enhance surgical intervention in a patient with a complex

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2017 3D Printing in Medicine

151. Patient Satisfaction & Retention of Milled, 3D Printed and Conventional Complete Dentures

for nesting each file for the suitable PMMA block size and height, ready for milling them in denture bases with Dental Concept DC1 . After milling denture bases, acrylic teeth will be chosen for each patient with the suitable shade and size following the inter-arch space, then glued by auto-polymerizing resin in their corresponding sockets in the milled denture bases. In second intervention: STL files will be imported to Rapidshape D30 3D-printer CAM software followed by adjusting the object (...) to be virtually placed on X,Y and Z axes on the printer plate to be ready for layering it in three dimension. Photopolymerizable PMMA liquid resin will be added in the printer and the files processed into 3D printed upper and lower denture bases. Acrylic teeth are then glued in their sockets in the printed denture bases using auto-polymerizable resin. In control group:Conventional complete denture construction by normal processing steps will be made for patients enrolled in the control group. For the three

2017 Clinical Trials

152. Patient Specific Template Guided Pedicle Instrumentation Versus Free Hand Technique

the entry points as well as the direction of the screw. Also, replicas of the individual vertebra are produced in the 3D printer. The patients are operated in a prone position via a dorsal approach. After preparation of the dorsal process, vertebral arches and vertebral joints as well as the transverse process, the screws are implanted with one of the following methods depending on the randomization: Freehand (fluoroscopically controlled) MySpine System Postoperatively, all patients undergo computed (...) system than by the conventional free-hand method using intraoperative fluoroscopy. Condition or disease Intervention/treatment Phase Spinal Cord Diseases Procedure: spondylodesis Procedure: CT Not Applicable Detailed Description: Patients with an indication for spondylodesis are included according to the inclusion criteria and exclusion criteria. Subsequently, randomization into the MySpine and conventional group is performed. Patients remain blinded to the randomization. On the basis of a computed

2017 Clinical Trials

153. Craniofacial Applications of 3D Printing

, University of Maryland Study Details Study Description Go to Brief Summary: 3D printing is a technology that allows for physical creation of a 3D model (usually made of plastic) based on computer generated 3D images from CT scans. The 3D images of craniofacial skeleton using computer software are routinely generated and, in turn, these 3D images can be used to create a plastic 3D model using a 3D printer. Unstable or comminuted facial fractures need to be reduced and rigidly fixated using titanium plates (...) of treatment. The purpose of this study is to explore whether custom plastic models 3D printed at Shock Trauma Center and used for bending and shaping plates for facial fracture repair can improve results of facial fracture reconstruction. Our plastic surgery division will design and produce facial bone 3D model of patients (with facial fractures) using an in-house 3D printer, then use the 3D model to contour the hardware pre-op or intra-op at the time of fracture repair. We believe that we can achieve

2017 Clinical Trials

154. iGEM blogs: Making Life in Space Easier by CosmoCrops

before launching, simply just the co-culture, spores of B. subtilis and a 3D printer – then everything else can be made out in space. It will also be used for future settlements on other planets, so they are not dependent on Earth for materials, but can produce what they need by themselves. Thereby, making the lives of new settlers easier than it otherwise would be. The CosmoCrops CosmoCrops is an interdisciplinary team from University of Copenhagen that consists of 10 undergraduate and graduate (...) . Physics Andrea Cordes – Stud. BSc. Computer Sciences Nikolaj Kristensen – Stud. BSc. Molecular Biomedicine Joachim Larsen – Stud. MSc. Biology-Biotechnology Iris Madsen – Stud. BSc. Mathematics Stael Naseri – Stud. BSc. Nanotechnology Thue Nikolajsen – Stud. BSc. Physics Joseph Parker – Stud. MSc. Biochemistry Giulia Perotti – Stud. MSc. Physical chemistry References Ducat D.C., Avelar-Rivas J.A., Way J.C. & Silvera P.A. (2012) Rerouting carbon flux to enhance photosynthetic productivity. Applied

2016 PLOS Blogs Network

155. Ruth Bonnington: Thoughts on the NHS from a GP

, reviewing results, fighting the crashing computer system, and dictating letters that I get to at 18h30 and still have a few phone calls still to make. Then I’m grateful for my manager and staff who have sorted out the printer, sent off our paper work and evidence to NHS England or the CCG and prepared the protocols for a CQC inspection. And I’m grateful to my husband who may have started the stir fry and is not too irritated that I’m late again or that I didn’t get home from my half day till 17h30

2016 The BMJ Blog

156. Development of three-dimensional prints of arthritic joints for supporting patients’ awareness to structural damage (PubMed)

high-resolution peripheral quantitative computed tomography (HR-pQCT) to develop 3D prototypes of patients' finger joints.HR-pQCT (XtremeCT, Scanco) measurements were performed in healthy individuals and patients with inflammatory joint disease, followed by a 3D print using the objet30 printer. Healthy participants (n = 10), and patients (n = 15 with RA and 15 with PsA) underwent a detailed, standardized interview with demonstration of printed joints.Utilizing HR-pQCT images of metacarpophalangeal

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2017 Arthritis research & therapy

157. 3D Printing of Biomolecular Models for Research and Pedagogy (PubMed)

3D Printing of Biomolecular Models for Research and Pedagogy The construction of physical three-dimensional (3D) models of biomolecules can uniquely contribute to the study of the structure-function relationship. 3D structures are most often perceived using the two-dimensional and exclusively visual medium of the computer screen. Converting digital 3D molecular data into real objects enables information to be perceived through an expanded range of human senses, including direct stereoscopic (...) parameters is difficult and time consuming without detailed guidance. Here, we provide a guide on the digital design and physical fabrication of biomolecule models for research and pedagogy using open source or low-cost software and low-cost 3D printers that use fused filament fabrication technology.

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2017 Journal of visualized experiments : JoVE

158. Intraoperative Change in Defect Size during Maxillary Reconstruction Using Surgical Guides Created by CAD/CAM (PubMed)

Intraoperative Change in Defect Size during Maxillary Reconstruction Using Surgical Guides Created by CAD/CAM Surgical osteotomy guides created by computer-aided design/computer-aided manufacturing (CAD/CAM) have been developed and are now widely used in maxillofacial reconstruction. However, there are no standard procedures for dealing with an intraoperative change in defect size. We report on a case in which we used our CAD/CAM guides to deal with an intraoperative change in defect size (...) in a maxillary reconstruction. We planned the maxillary reconstruction using a free fibula flap because of left maxillary sinus cancer in a 73-year-old man. In Japan, we cannot use commercially supplied CAD/CAM guides because these have not been approved by the government. We created novel CAD/CAM guides by using free software and a low-cost 3D printer. We performed model surgery to check the accuracy of the design and to prebend the titanium plates before the operation. The actual defect in the maxilla

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2017 Plastic and Reconstructive Surgery Global Open

159. Using a handheld stereo depth camera to overcome limited field-of-view in simulation imaging for radiation therapy treatment planning (PubMed)

Using a handheld stereo depth camera to overcome limited field-of-view in simulation imaging for radiation therapy treatment planning A correct body contour is essential for reliable treatment planning in radiation therapy. While modern medical imaging technologies provide highly accurate patient modeling, there are times when a patient's anatomy cannot be fully captured or there is a lack of easy access to computed tomography (CT) simulation. Here, we provide a practical solution (...) to merge the mesh model with the CT and fill in the missing surface information thereby obtaining a complete surface model of the subject. To evaluate the accuracy of the proposed approach, experiments were performed with the following steps. First, we selected three previously treated patients and fabricated a phantom mimicking each patient using the corresponding CT images and a 3D printer. Second, we removed part of the CT images of each patient to create hypothetical cases with image truncations

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2017 Medical physics

160. Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas (PubMed)

Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas The objective of this study was to determine the use of 3D printed model of an eye with intraocular tumor for linear accelerator-based stereotactic radiosurgery.The software for segmentation (3D Slicer) created virtual 3D model of eye globe with tumorous mass based on tissue density from computed tomography and magnetic resonance imaging data. A virtual model was then processed (...) in the slicing software (Simplify3D®) and printed on 3D printer using fused deposition modeling technology. The material that was used for printing was polylactic acid.In 2015, stereotactic planning scheme was optimized with the help of 3D printed model of the patient's eye with intraocular tumor. In the period 2001-2015, a group of 150 patients with uveal melanoma (139 choroidal melanoma and 11 ciliary body melanoma) were treated. The median tumor volume was 0.5 cm3 (0.2-1.6 cm3). The radiation dose

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2017 Clinical ophthalmology (Auckland, N.Z.)

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