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121. Inotropic and Vasoactive Agents for In-Hospital Heart Failure Management

A, MacDonald P, Keogh A. Haeomodynamic, neurohormonal and symptomatic effects of dobutamine, dopamine and milrinone in severe heart failure [abstract]. Aust N Z J Med. 1998;28(1):79-152. (18) Review Manager (RevMan) [Computer program]. Version 5.1. Copenhagen (DK): The Nordic Cochrane Centre, The Cochrane Collaboration; 2011. (19) Deeks J, Higgins J, Altman D, on behalf of the Cochrane Statistical Methods Group (editors). Cochrane handbook for systematic reviews of interventions [Internet]. Version 5.1.0 (...) . The Cochrane Collaboration; 2011 [cited 2012 Oct 16]. Chapter 9, Analysing data and undertaking meta-analysis. 2011. Available from: http://www.cochrane-handbook.org Inotropic and Vasoactive Agents for In-Hospital Heart Failure Management: A Rapid Review. December 2012; pp. 1–19. 19 Health Quality Ontario 130 Bloor Street West, 10 th Floor Toronto, Ontario M5S 1N5 Tel: 416-323-6868 Toll Free: 1-866-623-6868 Fax: 416-323-9261 Email: EvidenceInfo@hqontario.ca www.hqontario.ca © Queen’s Printer for Ontario

2012 Health Quality Ontario

122. Benefits and Limitations of Entry-Level 3-Dimensional Printing of Maxillofacial Skeletal Models. (PubMed)

previously undergone pediatric craniofacial reconstruction with use of a commercially produced medical model for surgical planning. Each vendor model had been produced using computed tomographic imaging data. With the use of this same data source, in-house models were printed in polylactic acid using a commercially available printer. Data were collected from November 1 to December 30, 2015.Models created from these 2 methods of production were assessed for fidelity of surface anatomy, resilience (...) Benefits and Limitations of Entry-Level 3-Dimensional Printing of Maxillofacial Skeletal Models. A protocol for creating exceptionally low-cost 3-dimensional (3-D) maxillofacial skeletal models does not require proficiency with computer software or intensive labor. Small and less affluent centers can produce models with little loss in accuracy and clinical utility.To highlight the feasibility and methods of introducing in-house, entry-level additive manufacturing (3-D printing) technology

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2017 JAMA otolaryngology-- head & neck surgery

123. Three-dimensional printing of navigational template in localization of pulmonary nodule: A pilot study. (PubMed)

. This study aims to investigate its feasibility in clinical application.Patients with peripheral lung nodules (<2 cm) were enrolled. Preadmission computed tomography images were downloaded and reconstructed into a 3D model. A digital model of the navigational template was designed via computer-aided design software and then exported into 3D printer to produce physical template. The precision of the template-guided nodule localization and associated complications were evaluated.A total of 16 patients were (...) acceptable accuracy for the application in lung nodule localization. The use of this navigational template could facilitate the procedure of lung nodule localization and may potentially break the dependence of percutaneous localization on computed tomography scanning.Copyright © 2017. Published by Elsevier Inc.

2017 Journal of Thoracic and Cardiovascular Surgery

124. A medical student in therapy

this appointment for a month. In March, I started to take an online physiology exam for school but instead spent twenty minutes staring motionless at the computer screen. I eventually input the answers and passed the test, but I’d stopped caring. A week later, I had a panic attack while riding the 6 train through Midtown Manhattan at rush hour. I’d already been feeling trapped by the tightly scheduled lifestyle of a medical student, and getting sandwiched between strangers inside an underground tube (...) of concrete didn’t help. In late April, I scheduled an appointment with my school’s counseling program. An attending psychiatrist did my initial interview: She was warm, and we spoke for over an hour in her well-lit office before she referred me to Dr. Hassan, one of her residents. Dr. Hassan’s soft voice makes me aware of the silence surrounding us. I hear no coworkers rustling about outside her basement-office door, no printers whirring in the background. Her movements are slow and deliberate

2017 KevinMD blog

125. Horizontal ridge reconstruction of the anterior maxilla using customized allogeneic bone blocks with a minimally invasive technique - a case series. (PubMed)

a 3D printed hardcopy model of the maxilla to prepare customized milled bone blocks, to be adapted on the bone defect areas using a minimally invasive subperiosteal tunneling technique.Cone beam computed tomography (CBCT) images of the atrophic maxilla of six patients were acquired and modified into 3D reconstruction models. Data were transferred to a 3D printer and solid models were fabricated using autoclavable nylon polyamide. Before the surgery, freeze-dried cortico-cancellous blocks were

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2017 BMC Oral Health

126. Evaluating the morphology of the left atrial appendage by a transesophageal echocardiographic 3-dimensional printed model. (PubMed)

occlusion, and preprocedure 3D TEE and cardiac computed tomography were enrolled. 3D TEE volumetric data of the LAA were acquired and postprocessed for 3DP. Two types of 3D models of the LAA (ie, hard chamber model and flexible wall model) were printed by a 3D printer. The morphological classification and lobe identification of the LAA were assessed by the 3D chamber model, and LAA dimensions were measured via the 3D wall model. Additionally, a simulation operative rehearsal was performed on the 3D (...) models in cases of challenging LAA morphology for the purpose of understanding the interactions between the device and the model.Three-dimensional TEE volumetric data of the LAA were successfully reprocessed and printed as 3D LAA chamber models and 3D LAA wall models in all patients. The consistency of the morphological classifications of the LAA based on 3D models and cardiac computed tomography was 0.92 (P < .01). The differences between the LAA ostium dimensions and depth measured using the 3D

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2017 Medicine

127. Circumferential Three-Dimensional-Printed Tracheal Grafts: Research Model Feasibility and Early Results. (PubMed)

models of porcine subject tracheas were generated using preoperative computed tomography scans. Two designs were used to test graft customizability and the limits of the construction process. Designs I and II used 270-degree and 360-degree external polycaprolactone scaffolds, respectively, both encompassing a circumferential extracellular matrix collagen layer. The polycaprolactone scaffolds were made in a fused-deposition modeling 3D printer and customized to the recipient's anatomy. Design I

2017 Annals of Thoracic Surgery

128. Development of a Tailored Thyroid Gland Phantom for Fine-Needle Aspiration Cytology by Three-Dimensional Printing. (PubMed)

, and ultrasonographic (US) characteristics.A three-dimensional (3D) digital model of the human neck was reconstructed from computed tomography data of a subject. This model was used to create 3D-printed templates for various organs that require US visualization. The templates were injected with polymers that provided similar degrees of ultrasound permeability as the corresponding organs. For fabrication of each organ, the respective molds of organs, blood vessels, thyroid gland, and tumor were injected (...) . In the survey, all 45 participants replied that they found the phantom useful for FNAC training, and 30 medical students professed increased interest in thyroid diseases after using the phantom.We successfully fabricated a tailored thyroid gland phantom for transfixion practice. As most of the phantom parts are injected in molds fabricated using a 3D printer, they can be easily reproduced once the molds are fabricated. This phantom is expected to serve as an effective and fully tailored training model

2017 Journal of Surgical Education

129. Evaluation of Different Techniques for Filling Simulated C-shaped Canals of 3-dimensional Printed Resin Teeth. (PubMed)

Evaluation of Different Techniques for Filling Simulated C-shaped Canals of 3-dimensional Printed Resin Teeth. The purpose of this study was to compare the ability of different root canal filling methods on the C1 root canal anatomy using 3-dimensional (3D) printer technology.Mandibular molars were scanned with cone-beam computed tomographic (CBCT) imaging. A mandibular molar tooth with a C1 root canal configuration was selected according to images obtained from CBCT technology. The root canals (...) were shaped with ProTaper Universal rotary instruments (Dentsply Maillefer, Ballaigues, Switzerland) and hand files. After the root canal shaping procedure, the tooth was scanned with micro-computed tomographic imaging, and 80 replicas of the tooth were produced with a 3D printer. Replicas were assigned into 4 groups (n = 20) and were filled using one of the following techniques: a core carrier system (GuttaCore [GC]; Dentsply Tulsa Dental Specialties, Tulsa, OK), a continuous wave obturation

2017 Journal of Endodontics

130. Accuracy of printed dental models made with 2 prototype technologies and different designs of model bases. (PubMed)

printers using different techniques: stereolithography and triple jetting technology (polyjet). The printed models were then scanned with a computed tomography scanner and a desktop laser scanner to create the respective digital models. Evaluation of the accuracy was done by measuring the dentitions with Ortho Analyzer software (3Shape, Copenhagen, Denmark) and by model superimposition with Geomagic Qualify software (3D Systems, Rock Hill, SC). An observer measured the distances twice, with an interval (...) of 2 weeks. The accuracy of the printed models was statistically evaluated by the mixed-effects regression model approach.The results showed that printed models made by the polyjet printer were accurate, regardless of the design of the model base. Printed models made with the stereolithography technique with the regular model base and the horseshoe-shaped base with a bar were accurate, but the transversal distances measured on the printed models with a horseshoe-shaped base were statistically

2017 American journal of orthodontics and dentofacial orthopedics

131. Creating an Optimal 3D Printed Model for Temporal Bone Dissection Training. (PubMed)

Creating an Optimal 3D Printed Model for Temporal Bone Dissection Training. Making a 3-dimensional (3D) temporal bone model is simple using a plaster powder bed and an inkjet printer. However, it is difficult to reproduce air-containing spaces and precise middle ear structures. The objective of this study was to overcome these problems and create a temporal bone model that would be useful both as a training tool and for preoperative simulation.Drainage holes were made to remove excess materials (...) from air-containing spaces, ossicle ligaments were manually changed to bony structures, and small and/or soft tissue structures were colored differently while designing the 3D models. The outcomes were evaluated by 3 procedures: macroscopic and endoscopic inspection of the model, comparison of computed tomography (CT) images of the model to the original CT, and assessment of tactile sensation and reproducibility by 20 surgeons performing surgery on the model.Macroscopic and endoscopic inspection

2017 Rhinology and Laryngology

132. Cardiac 3D Printing and its Future Directions. (PubMed)

Cardiac 3D Printing and its Future Directions. Three-dimensional (3D) printing is at the crossroads of printer and materials engineering, noninvasive diagnostic imaging, computer-aided design, and structural heart intervention. Cardiovascular applications of this technology development include the use of patient-specific 3D models for medical teaching, exploration of valve and vessel function, surgical and catheter-based procedural planning, and early work in designing and refining the latest

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2017 JACC. Cardiovascular imaging

133. Microguided Endodontics: Accuracy of a Miniaturized Technique for Apically Extended Access Cavity Preparation in Anterior Teeth. (PubMed)

. Preoperative surface and cone-beam computed tomography scans were matched by using the coDiagnostix software. Virtual planning was performed for the access cavities, and templates were used for guidance. The templates were produced by a three-dimensional printer. Two operators performed the access cavities. A postoperative cone-beam computed tomography scan was superimposed on the virtual plan, and the deviation was measured in 3 dimensions and angles. Descriptive statistical analyses were performed

2017 Journal of Endodontics

134. Value of 3D printing for the comprehension of surgical anatomy. (PubMed)

information.Fifteen patients scheduled for laparoscopic splenectomy, nephrectomy, or pancreatectomy were selected and, for each, a full-size 3D virtual anatomical object was reconstructed from a contrast-enhanced MDCT (Multiple Detector Computed Tomography) and then prototyped using a 3D printer. After having carefully evaluated-in a random sequence-conventional contrast MDCT scans, virtual 3D reconstructions on a flat monitor, and 3D-printed models of the same anatomy for each selected case, thirty subjects

2017 Surgical endoscopy

135. A New Spinal Brace Design Concept for the Treatment of Adolescent Idiopathic Scoliosis

which can improve brace design. However, it is still quite time consuming to construct a brace. Although 3D printing technology has been proposed to construct a scoliosis brace, its effectiveness has not been validated. The goals of this study was to investigate if an effective and comfortable brace can be designed and fabricated by using ultrasound and computer-aided design and computer-aided manufacturing (CAD/CAM) technology, and be printed directly from a 3D printer with faster production, lower (...) or less than 1 year postmenarchal. The 50 subjects will be randomly assigned to 2 equally sized groups (n=25 in each group): group A conventional designed and manual fabricated braces and group B ultrasound and CAD/CAM scanner designed brace with printing by a 3D printer. Both groups: A brace monitor (2.5cm x 4.0cm x 1.5 cm and 8g) developed from our group will be installed into all braces for both study groups. It will monitor patients' compliance which includes how much time they use their braces

2017 Clinical Trials

136. Preoperative planning and tracheal stent design in thoracic surgery: a primer for the 2017 Radiological Society of North America (RSNA) hands-on course in 3D printing (PubMed)

superior sulcus tumor. Furthermore, patient-specific device creation is demonstrated using dedicated computer-aided design software. Relevant anatomy for these tasks is obtained from CT Digital Imaging and Communications in Medicine images, leading to the generation of 3D printable files and delivery of these files to a 3D printer. (...) Preoperative planning and tracheal stent design in thoracic surgery: a primer for the 2017 Radiological Society of North America (RSNA) hands-on course in 3D printing In this work, we provide specific clinical examples to demonstrate basic practical techniques involved in image segmentation, computer-aided design, and 3D printing. A step-by-step approach using United States Food and Drug Administration cleared software is provided to enhance surgical intervention in a patient with a complex

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2017 3D Printing in Medicine

137. Patient Satisfaction & Retention of Milled, 3D Printed and Conventional Complete Dentures

for nesting each file for the suitable PMMA block size and height, ready for milling them in denture bases with Dental Concept DC1 . After milling denture bases, acrylic teeth will be chosen for each patient with the suitable shade and size following the inter-arch space, then glued by auto-polymerizing resin in their corresponding sockets in the milled denture bases. In second intervention: STL files will be imported to Rapidshape D30 3D-printer CAM software followed by adjusting the object (...) to be virtually placed on X,Y and Z axes on the printer plate to be ready for layering it in three dimension. Photopolymerizable PMMA liquid resin will be added in the printer and the files processed into 3D printed upper and lower denture bases. Acrylic teeth are then glued in their sockets in the printed denture bases using auto-polymerizable resin. In control group:Conventional complete denture construction by normal processing steps will be made for patients enrolled in the control group. For the three

2017 Clinical Trials

138. Patient Specific Template Guided Pedicle Instrumentation Versus Free Hand Technique

the entry points as well as the direction of the screw. Also, replicas of the individual vertebra are produced in the 3D printer. The patients are operated in a prone position via a dorsal approach. After preparation of the dorsal process, vertebral arches and vertebral joints as well as the transverse process, the screws are implanted with one of the following methods depending on the randomization: Freehand (fluoroscopically controlled) MySpine System Postoperatively, all patients undergo computed (...) system than by the conventional free-hand method using intraoperative fluoroscopy. Condition or disease Intervention/treatment Phase Spinal Cord Diseases Procedure: spondylodesis Procedure: CT Not Applicable Detailed Description: Patients with an indication for spondylodesis are included according to the inclusion criteria and exclusion criteria. Subsequently, randomization into the MySpine and conventional group is performed. Patients remain blinded to the randomization. On the basis of a computed

2017 Clinical Trials

139. Craniofacial Applications of 3D Printing

, University of Maryland Study Details Study Description Go to Brief Summary: 3D printing is a technology that allows for physical creation of a 3D model (usually made of plastic) based on computer generated 3D images from CT scans. The 3D images of craniofacial skeleton using computer software are routinely generated and, in turn, these 3D images can be used to create a plastic 3D model using a 3D printer. Unstable or comminuted facial fractures need to be reduced and rigidly fixated using titanium plates (...) of treatment. The purpose of this study is to explore whether custom plastic models 3D printed at Shock Trauma Center and used for bending and shaping plates for facial fracture repair can improve results of facial fracture reconstruction. Our plastic surgery division will design and produce facial bone 3D model of patients (with facial fractures) using an in-house 3D printer, then use the 3D model to contour the hardware pre-op or intra-op at the time of fracture repair. We believe that we can achieve

2017 Clinical Trials

140. iGEM blogs: Making Life in Space Easier by CosmoCrops

before launching, simply just the co-culture, spores of B. subtilis and a 3D printer – then everything else can be made out in space. It will also be used for future settlements on other planets, so they are not dependent on Earth for materials, but can produce what they need by themselves. Thereby, making the lives of new settlers easier than it otherwise would be. The CosmoCrops CosmoCrops is an interdisciplinary team from University of Copenhagen that consists of 10 undergraduate and graduate (...) . Physics Andrea Cordes – Stud. BSc. Computer Sciences Nikolaj Kristensen – Stud. BSc. Molecular Biomedicine Joachim Larsen – Stud. MSc. Biology-Biotechnology Iris Madsen – Stud. BSc. Mathematics Stael Naseri – Stud. BSc. Nanotechnology Thue Nikolajsen – Stud. BSc. Physics Joseph Parker – Stud. MSc. Biochemistry Giulia Perotti – Stud. MSc. Physical chemistry References Ducat D.C., Avelar-Rivas J.A., Way J.C. & Silvera P.A. (2012) Rerouting carbon flux to enhance photosynthetic productivity. Applied

2016 PLOS Blogs Network

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