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101. Development of three-dimensional brain arteriovenous malformation model for patient communication and young neurosurgeon education. (PubMed)

on personal computer and the rapid prototyping process was completed using a 3D printer. The size and morphology of the models were compared to brain digital subtraction arteriography of the same patients. 3D brain AVM models were used for preoperative patient communication and young neurosurgeon education.Two brain AVM models were successfully produced. By neurosurgeons' evaluation, the printed models have high fidelity with the actual brain AVM structures of the patients. The patient responded

2018 British Journal of Neurosurgery

102. Impact of 3D printing technology on the comprehension of surgical liver anatomy. (PubMed)

multi-detector computed tomography (MDCT) and was prototyped using a 3D printer. Forty-five surgical residents were evenly assigned to each group (3DP, VIR, and MDCT groups). After evaluation of the MDCT scans, VIR model, or 3DP model of each tumor, surgical residents were asked to assign hepatic tumor locations and state surgical resection proposals. The time used to specify the tumor location was recorded. The correct responses and time spent were compared between the three groups.The assignment

2018 Surgical endoscopy

103. Assessment of a Patient-Specific, 3-Dimensionally Printed Endoscopic Sinus and Skull Base Surgical Model. (PubMed)

performed from April 1, 2017, through June 1, 2017, a total of 7 otolaryngology residents and 2 attending physicians at a tertiary academic center were recruited to evaluate the procedural anatomical accuracy and haptic feedback of the printed model.A 3D model of sinus and skull base anatomy with high-resolution, 3D printed material (VeroWhite) was printed using a 3D printer. Anatomical accuracy was assessed by comparing a computed tomogram of the original patient with that of the 3D model across set (...) and navigation and haptic evaluation by the study participants.Seven otolaryngology residents (3 postgraduate year [PGY]-5 residents, 2 PGY-4 residents, 1 PGY-3 resident, and 1 PGY-2 resident) and 2 attending physicians evaluated the haptic feedback of the 3D model. Computed tomographic comparison demonstrated a less than 5% difference between patient and 3D model measurements. Image-guided navigation confirmed accuracy of 13 landmarks to within 1 mm. Likert scores were a mean (SD) of 4.00 (0.71) for overall

2018 JAMA otolaryngology-- head & neck surgery

104. Low-cost customized cranioplasty using a 3D digital printing model: a case report (PubMed)

-dimensional (3D) printing technique for cranial reconstruction. A digital prosthesis model is designed and manufactured with the aid of a 3D computed tomography. Both the data of large sized cranial defects and the prosthesis are transferred to a 3D printer to obtain a physical model in poly-lactic acid which is then used in a laboratory to cast the final customised prosthesis in polymethyl methacrylate (PMMA).A precise compliance of the prosthesis to the osseous defect was achieved. At the 6 month

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2018 3D Printing in Medicine

105. The subresolution DaTSCAN phantom: a cost-effective, flexible alternative to traditional phantom technology (PubMed)

slabs of attenuating material generated through additive manufacturing, and paper sheets with radioactive ink patterns printed on their surface, created with a conventional inkjet printer. The paper sheets and attenuating slabs are interleaved before scanning. Use of thin layers ensures that they cannot be individually resolved on reconstructed images. An investigation was carried out to demonstrate the performance of such a phantom in producing simplified I-FP-CIT uptake patterns. Single photon (...) emission computed tomography imaging was carried out on an assembled phantom designed to mimic a healthy patient. Striatal binding ratio results and linear striatal dimensions were calculated from the reconstructed data and compared with that of 22 clinical patients without evidence of Parkinsonian syndrome, determined from clinical follow-up. Striatal binding ratio results for the fully assembled phantom were: 3.1, 3.3, 2.9 and 2.6 for the right caudate, left caudate, right putamen and right caudate

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2018 Nuclear medicine communications

106. Three-Dimensional Printing-based Reconstruction of a Maxillary Bone Defect in a Dog Following Tumor Removal (PubMed)

. Based on computed tomography images, a defect was confirmed on the maxillary bone due to the oral mass, and a surgical plan was designed to remove the oral mass and graft the 3D printed scaffold. Customized polycaprolactone/ beta-tracalciumphosphate (PCL/β-TCP) scaffold was fabricated using the micro-extrusion-based 3D printer. In the operation, after the removal of the oral mass, the scaffold was grafted onto the defect site. At follow-up, 8 months after surgery, the result was successful without

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2018 In Vivo

107. Enhanced Preoperative Deep Inferior Epigastric Artery Perforator Flap Planning with a 3D-Printed Perforasome Template: Technique and Case Report (PubMed)

. Routine preoperative computed tomographic angiography was performed, with open-source software (3D Slicer, Autodesk MeshMixer and Cura) and a desktop 3D printer (Ultimaker 3E) used to create a template used to mark intra-flap, subcutaneous branches of deep inferior epigastric artery (DIEA) perforators on the abdomen. An individualized 3D printed template was used to estimate the size and boundaries of a perforasome and perfusion map. The information was used to aid flap design. We describe a new

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2018 Plastic and Reconstructive Surgery Global Open

108. Assemble-And-Match: A Novel Hybrid Tool for Enhancing Education and Research in Rational Structure Based Drug Design (PubMed)

Assemble-And-Match: A Novel Hybrid Tool for Enhancing Education and Research in Rational Structure Based Drug Design Rational drug design is the process of finding new medication that can activate or inhibit the biofunction of a target molecule by binding to it and forming a molecular complex. Here, shape and charge complementarities between drug and target are key. To help find effective drug molecules out of a huge pool of possibilities, physical and computer aided tools have been developed (...) . Former offers a tangible experience of the molecular interactions yet lacks measurement and evaluation capabilities. Latter enables accurate and fast evaluations, but does not deliver the interactive tangible experience of physical models. We introduce a novel hybrid model called "Assemble-And-Match" where, we enhance and combine the unique features of the two categories. Assemble-And-Match works based on fabrication of customized molecular fragments using our developed software and a 3D printer

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2018 Scientific reports

109. Application of 3D printing in the surgical planning of hypertrophic obstructive cardiomyopathy and physician-patient communication: a preliminary study (PubMed)

Application of 3D printing in the surgical planning of hypertrophic obstructive cardiomyopathy and physician-patient communication: a preliminary study The aim of this study was to evaluate the effect of 3-dimensional (3D) printing in treatment of hypertrophic obstructive cardiomyopathy (HOCM) and its roles in doctor-patient communication.3D-printed models were constructed preoperatively and postoperatively in seven HOCM patients received surgical treatment. Based on multi-slice computed (...) tomography (CT) images, regions of disorder were segmented using the Mimics 19.0 software (Materialise, Leuven, Belgium). After generating an STL-file (StereoLithography file) with patients' data, the 3D printer (Objet350 Connex3, Stratasys Ltd., USA) created a 3D model. The pre- and post-operative 3D-printed models were used to make the surgical plan preoperatively and evaluate the outcome postoperatively. Meanwhile, a questionnaire was designed for patients and their relatives to learn

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2018 Journal of thoracic disease

110. Three‐dimensional printing CT‐derived objects with controllable radiopacity (PubMed)

Three‐dimensional printing CT‐derived objects with controllable radiopacity The goal of this work was to develop phantoms for the optimization of pre-operative computed tomography (CT) scans of the prostate artery, which are used for embolization planning.Acrylonitrile butadiene styrene (ABS) pellets were doped with barium sulfate and extruded into filaments suitable for 3D printing on a fused deposition modeling (FDM) printer. Cylinder phantoms were created to evaluate radiopacity (...) as a function of doping percentage. Small-diameter tree phantoms were created to assess their composition and dimensional accuracy. A half-pelvis phantom was created using clinical CT images, to assess the printer's control over cortical bone thickness and cancellous bone attenuation. CT-derived prostate artery phantoms were created to simulate complex, contrast-filled arteries.A linear relationship (R = 0.998) was observed between barium sulfate added (0%-10% by weight), and radiopacity (-31 to 1454

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2018 Journal of Applied Clinical Medical Physics

111. Towards Additive Manufacture of Functional, Spline-Based Morphometric Models of Healthy and Diseased Coronary Arteries: In Vitro Proof-of-Concept Using a Porcine Template (PubMed)

Towards Additive Manufacture of Functional, Spline-Based Morphometric Models of Healthy and Diseased Coronary Arteries: In Vitro Proof-of-Concept Using a Porcine Template The aim of this study is to assess the additive manufacture of morphometric models of healthy and diseased coronary arteries. Using a dissected porcine coronary artery, a model was developed with the use of computer aided engineering, with splines used to design arteries in health and disease. The model was altered (...) to demonstrate four cases of stenosis displaying varying severity, based on published morphometric data available. Both an Objet Eden 250 printer and a Solidscape 3Z Pro printer were used in this analysis. A wax printed model was set into a flexible thermoplastic and was valuable for experimental testing with helical flow patterns observed in healthy models, dominating the distal LAD (left anterior descending) and left circumflex arteries. Recirculation zones were detected in all models, but were visibly

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2018 Journal of functional biomaterials

112. HOPE: Hybrid-Drive Combining Optogenetics, Pharmacology and Electrophysiology (PubMed)

injection cannulas for drug-delivery experiments. Because it can be printed with a latest-generation desktop 3D printer, the production cost is low compared to classical electrophysiology implants, and it can be built within a few hours. The HOPE implant is also reconfigurable to specific needs as it has been created in a computer-aided design (CAD) software and all the files used for its construction are open-source.

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2018 Frontiers in neural circuits

113. The Influence of Selective Laser Melting (SLM) Process Parameters on In-Vitro Cell Response (PubMed)

The Influence of Selective Laser Melting (SLM) Process Parameters on In-Vitro Cell Response The use of laser 3D printers is very perspective in the fabrication of solid and porous implants made of various polymers, metals, and its alloys. The Selective Laser Melting (SLM) process, in which consolidated powders are fully melted on each layer, gives the possibility of fabrication personalized implants based on the Computer Aid Design (CAD) model. During SLM fabrication on a 3D printer, depending

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2018 International journal of molecular sciences

114. Quality of Preanesthesia Teleconsultation : a Randomized Controlled Trial.

Nancy) Patient with technology equipments, which are compatible with the plateform of video-conference : smartphones, touch pads, computer web-browser ( chrome or internet explorer) Webcam and microphone Printer Exclusion Criteria: Patients covered by Articles L. 1121-5 to L. 1121-8, L1122-2 and L. 1122-1-2 of the french public health code. (Persons especially protected by Act) Patients refusing to participate to the study, or refusing the randomization for the group allocation. Preanesthesia

2018 Clinical Trials

115. Assessing the Accuracy of Caries Diagnosis in Bitewing Radiographs Using Different Reproduction Media (PubMed)

Assessing the Accuracy of Caries Diagnosis in Bitewing Radiographs Using Different Reproduction Media After introducing digital radiography, practitioners started reading radiographs from computer monitors; however, many still prefer hard-copy radiographs.This study aimed to assess the possible superiority of either type of radiograph recording media (computer monitor, film, or paper) in diagnosis and perception of the depth of the cariogenic lesions.Twenty digital bitewing radiographs (...) , obtained from 200 posterior extracted teeth, were displayed on an LG monitor and printed on paper and film using Kodak printers. Two observers independently measured lesions depth on the images. Serial sections of teeth were obtained and the sections were evaluated by a stereomicroscope to determine the actual depth of cariogenic lesions. The efficacy of the each medium was assessed by determining its specificity and sensitivity in comparison with those of histological images. Weighted kappa

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2018 Journal of dentistry

116. MULTI-INSTITUTIONAL EVALUATION OF PRODUCING AND TESTING A NOVEL 3D-PRINTED LAPAROSCOPIC TRAINER. (PubMed)

MULTI-INSTITUTIONAL EVALUATION OF PRODUCING AND TESTING A NOVEL 3D-PRINTED LAPAROSCOPIC TRAINER. To create, distribute, and evaluate the efficacy of a portable, cost-effective 3D-printed laparoscopic trainer for surgical skills development.The UCI Trainer (UCiT) laparoscopic simulator was developed via computer-aided designs (CAD), which were used to 3D-print the UCiT. Once assembled, a tablet computer with a rear-facing camera was attached for video and optics. Four institutions were sent (...) the UCiT CAD files with a 3D-printer and instructions for UCiT assembly. For a comparison of the UCiT to a standard trainer, peg transfer and intracorporeal knot tying skills were accessed. These tasks were scored, and participants were asked to rate their experience with the trainers. Lastly, a questionnaire was given to individuals who 3D-printed and assembled the UCiT.We recruited 25 urologists; none had any 3D-printing experience. The cost of printing each trainer was $26.50 USD. Each institution

2018 Urology

117. Will artificial intelligence ever replace doctors?

times ahead for the Airline Pilots Association. Making precision tools from 3D printers. Gourmet meals created with a voice-activated command. Theater and film productions starring faux actors created on keyboards. Will artificial intelligence invade the medical arena? The question is only how deeply it will invade. The role of the traditional physician is at risk of being marginalized as computer software hits the profession hard. Sure, computers cannot palpate an abdomen or perform a rectal exam (...) that sophisticated computer algorithms can synthesize an individual’s personal medical data and generate specific diagnoses, many of which might not have been considered by a human physician. Of course, there’s a lot more to being a decent physician than spitting out a list of diagnoses, as we doctors know despite when empowered patients bring us lists of diseases they think they have after spending some time in the Google School of Medicine. Although artificial intelligence is not a real doctor, it offers

2018 KevinMD blog

118. It’s time to upgrade the outdated intake forms at health care clinics

eleven-page patient questionnaire with instructions to print and complete the form prior to my visit. Like many, I lacked immediate access to a printer. After showing up to my appointment without the form, I was expected to complete it in the clinic’s lobby. As a returning patient of this health system, most of the information asked was already available in the electronic health record (EHR). Did they really need to ask me about my city of birth again? What is already known in the EHR should populate (...) from any computer, tablet or phone, so that our patients can fill out this information in their own time and native language. The forms employ predictive follow up questions and synchronize with the EHR so that patients are prompted to complete only information that needs updating. Some of these companies even provide educational content to give patients context on the questions that they are being asked and the consents that they are signing. I have seen first hand how competitive the health care

2018 KevinMD blog

119. A novel method for periapical microsurgery with the aid of 3D technology: a case report. (PubMed)

A novel method for periapical microsurgery with the aid of 3D technology: a case report. Three-dimensional (3D) technology has gained wide acceptance in dentistry. It has been used for treatment planning and surgical guidance. This case report presented a novel treatment approach to remove cortical bone and root-end during periapical surgery with the help of Cone-Beam Computed Tomography (CBCT), Computer Aided Design (CAD) and three-dimensional (3D) printing technology.A 37-year-old female (...) patient presented with a large periapical lesion of left maxillary lateral incisor and canine was referred for microsurgical endodontic surgery. The data acquired from a preoperative diagnostic CBCT scan and an intra-oral scan was uploaded into surgical planning software and matched. A template that could be used to locate root-ends and lesion areas was virtually designed based on the data and was fabricated using a 3D printer. With the guidance of the template, the overlying cortical bone and root

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2018 BMC Oral Health

120. Outcome and safety analysis of 3D printed patient specific pedicle screw jigs for complex spinal deformities: A comparative study. (PubMed)

reconstruction from computed tomography scan images of all the patients. 3-Matic software was used to create a drill guide. A 3D printer from Stratasys Mojo with ABS P430 model material cartilage (a thermoplastic material) was used for the printing of the vertebra model and jigs. A two-sample test of proportion was used to compare correctly and wrongly placed pedicle screws with 3D printing and freehand technique. t Test with equal variance was used for operating surgical time and blood loss.No superior

2018 The Spine Journal

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