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42. Flash Glucose Monitoring System for People with Type 1 or Type 2 Diabetes

. This information is sought from accuracy studies in the literature (the focus is on the proportion of values that fall in the C, D, and E regions of the Clarke error grid). 2. Derive the sum of hypoglycemic events in intervention arms from the reported average number of hypoglycemic events. 3. Using the error rate reported in each accuracy study, estimate the number of misclassified events in Haak et al and Bolinder et al. This is computed as the product of reported events in Haak et al and Bolinder et al (...) and the error rate in accuracy studies. Error rates are randomly drawn from a probability distribution that reflect their plausibility of occurrence. In our case we used the uniform distribution because no information in the literature suggests whether certain levels of misclassification errors are more likely than others. 4. For each randomly selected error value, compute the corrected number of hypoglycemic events in Haak et al and Bolinder et al by subtracting the reported number of events in each

2019 Health Quality Ontario

43. Delivering novel therapies in the 21st century

and Professor Richard Jude Samulski.Delivering novel therapies in the 21st century – Conference report 22 • Manufacturing ‘to order’ for these advanced, personalised medicines may become more of the norm over manufacturing to stock. • Manufacturing is currently expensive, but automation (including use of decentralised 3D printers) will enable a reduction of cost and complexity in production of personalised medicines, and increased consistency in the manufacturing process. This will make room for greater

2019 Academy of Medical Sciences

44. Empowering Caregivers to Deliver Home-based Restorative Care

of interventions (e.g., web-based, group-based, etc.) rather than examining whether the content met caregivers’ needs.(19; 25; 26; 33-39) In general, these reviews focused on the use of technology, including web- and computer-mediated programs to deliver information, education, training, and psychosocial and behavioural supports to improve the quality of life of caregivers and those they are caring for.(19; 25; 26; 33-37; 39) These reviews found that the use of technology as a mode of delivery is on average (...) to return to materials (e.g., replaying videos in different modules), using a variety of activities that include both visual or auditory stimulation (materials that only include text are of limited value), and using motivating exercises and real-world examples. • A second but older overview of systematic reviews evaluated computer-mediated continuing education for healthcare professionals and found that professionals were satisfied with computer-mediated continuing programs, and that comparisons between

2019 McMaster Health Forum

45. Physiotherapy

Update on Physiotherapy Rehabilitation After Total Knee or Hip Replacement: OHTAC Recommendation. March 2014; pp. 1–9 Suggested Citation This report (...) should be cited as follows: Ontario Health Technology Advisory Committee (OHTAC). Update on physiotherapy rehabilitation after total knee or hip replacement: OHTAC recommendation [Internet]. Toronto: Queen's Printer for Ontario; 2014 March. 9 p. Available from: (...) . User login Username or e-mail: * Password: * Keep me logged in (Don't choose this option on a shared computer) Don't have an account yet (...) ? Need help? Clinical guidelines for the pre and post operative physiotherapy management of adults with lower limb amputation What physiotherapy management constitutes best practice for adults requiring lower limb amputation? These guidelines address the question: 'What physiotherapy management constitutes best practice for adults requiring lower limb

2018 Trip Latest and Greatest

46. Examining the Public Provision and Funding of PET-CT Imaging for Non-cancer Indications

indications have Canadian and Organisation for Economic Cooperation and Development (OECD) health systems included PET-CT in packages of care, and what payment models are used to support its delivery? Why the issue is important • Positron emission tomography–computed tomography (better known as PET-CT) has revolutionized medical diagnosis. • While PET-CT scanners have been predominantly used in oncology, they are now increasingly used in various disciplines such as general internal medicine, infectiology (...) plans. Examining the Public Provision and Funding of PET-CT Imaging for Non-cancer Indications 4 Evidence >> Insight >> Action QUESTION For what non-cancer indications have Canadian and Organisation for Economic Cooperation and Development (OECD) health systems included PET- CT in packages of care, and what payment models are used to support its delivery? WHY THE ISSUE IS IMPORTANT Positron emission tomography–computed tomography (better known as PET-CT) has revolutionized medical diagnosis since

2018 McMaster Health Forum

47. Identifying Performance Measures, Indicators and Targets to Monitor and Evaluate Dementia Strategies

type of dementia; o diagnostic work-up – e.g., blood test, clock test, CT, MRI, lumbar puncture, positron emission tomography/single photon emission computed tomography, electroencephalography, advanced cognitive testing, assessment by occupational therapist, assessment by physiotherapist, assessment by speech therapist (yes/no/don’t know); o total number of diagnostic tests; o Mini Mental State Examination score; o Medication – e.g., cholinesterase inhibitors, n-methyl-D-aspartate antagonist

2018 McMaster Health Forum

48. An Overview of Clinical Applications of 3-D Printing and Bioprinting

that, in general, share the following common components: 7,14,26 data (e.g., images) for the design software to use computer software for modelling, designing, and translating digital models into printer instructions a computer-controlled printer appropriate layering materials for producing the desired object. Common production techniques for 3-DP and bioprinting used in clinical applications are described in Table 1. Table 1: Description of Common Production Techniques for 3-D Printing and Bioprinting 3-DP (...) , but the powder is heated by the laser to the point that it fully melts, creating a homogenous part. It may be used if you are only using a single metal powder. The material is stronger but the porosity cannot be controlled. Selective heat sintering (SHS) 32 Similar to SLS but uses a thermal print head as opposed to a laser to sinter the powder. It allows the printer to be smaller in size. Material Extrusion Fused filament fabrication (FFF) 28 b Forms an object using a computer-controlled extrusion nozzle

2019 CADTH - Issues in Emerging Health Technologies

49. HTA of C-reactive protein point-of-care testing to guide antibiotic prescribing

, scanners and barcode label printers may be required to facilitate information transfer of the batch and lot number of the assay vial to the electronic health record of the patient. The facility to either scan or directly upload results into the clinical record and laboratory information management system would be beneficial when considering any potential future wide-scale procurement of CRP POCT analysers. (38) It would fall within the remit of the national POCT steering committee to set the technical

2019 Health Information and Quality Authority

50. Custom-made or customisable 3D printed implants and cutting guides versus non-3D printed standard implants and cutting guides for improving outcome in patients undergoing knee, maxillofacial, or cranial surgery

7.1 RESEARCH QUESTIONS 50 7.2 RESULTS 50 8 DISCUSSION 53 9 CONCLUSION 57 10 REFERENCES 58 APPENDIX 1: METHODS AND DESCRIPTION OF THE EVIDENCE USED 63 APPENDIX 2: CHECKLIST FOR POTENTIAL ETHICAL, ORGANISATIONAL, PATIENT AND SOCIAL AND LEGAL ASPECTS 79 APPENDIX 3: TEC DOMAIN - 3D PRINTERS FOR IMPLANTS AND CUTTING GUIDES 81 Custom-made 3D printed implants and cutting guides in knee, maxillofacial, or cranial surgery EUnetHTA Joint Action 3 WP4 5 LIST OF TABLES AND FIGURES Tables Table 1.1: Summary (...) Figure 6.10: 3D print vs. standard; outcome: operating time, patients undergoing knee reconstruction 46 Figure 6.11: 3D print vs. standard; outcome: Oxford Knee Score, patients undergoing knee reconstruction 48 Custom-made 3D printed implants and cutting guides in knee, maxillofacial, or cranial surgery EUnetHTA Joint Action 3 WP4 6 LIST OF ABBREVIATIONS ABS Acrylonitrile butadiene styrene AM Additive manufacturing CAD Computer-aided design CDSR Cochrane Database of Systematic Reviews CI Confidence

2019 EUnetHTA

52. Counselling for Chlamydia Case Management: A Rapid Review

effective when conducted in- person (individually or in a group setting) rather than delivered using computer, audiotape or video (15). Counselling achieved greater effectiveness when it was provided to ethnic minority participants or if the control group differed from standard care (e.g., wait list only) (15). 9 Ethnic minority groups included African Caribbean Black, Hispanic, and Asian ethnicities. 17 Successful interventions provided information about STIs and transmission, skill training 10 (...) standards: requirements for programs, services, and accountability, 2018 [standards on the internet]. Toronto, ON: Queen’s Printer for Ontario; 2018 Jul [cited 2018 Sept 19]. 75 p. Available from: 3. The Region of Peel - Public Health [healthy sexuality homepage on the internet]. C2018 [cited 2018 Sept 19]. Available from: 4. Ontario Ministry of Health and Long-Term Care. Sexual

2019 Peel Health Library

53. Responsible use of high-risk medical devices: the example of 3D printed medical devices

regulatory implications 5 : ? Printer: this may be a generic multipurpose device or be intended for a narrowly defined purpose. ? The commonly used materials (“ink” equivalents) are metals, plastic, ceramic and glass. ? Software to drive the printer. This may be generic or specific to a particular field. ? Software to design the object to be printed, e.g. Computer Aided Design (CAD). ? Product specification. This is likely to be a set of data that is used by the software to print the desired object. KCE (...) , implant and surgical instrument 11 Figure 3 – 3D printing manufacturing process chart (USA) 14 Figure 4 – 3D printing medical device process chart 14 Figure 5 – process and intervening parties for the 3D design/printing of a model 15 Figure 6 – Pooled estimate of mechanical axis misalignment using the RCT results from Thienpont et al. 16 23 Figure 7 – Pooled estimate of operative time using the RCT results from Thienpont et al. 16 24 Figure 8 – Conformity assessment procedures for 3D printers 46

2018 Belgian Health Care Knowledge Centre

54. Effects of early, computerized brief interventions on risky alcohol use and risky cannabis use among young people Full Text available with Trip Pro

), consisting of assessment, feedback, and decision‐making modules. Computerized brief interventions include both online and offline interventions (e.g., CD‐ROM, software, web sites and downloadable applications [apps]) delivered via electronic devices such as personal computers, tablets and smart phones. The main advantage of a computerized brief intervention is that it can reach large audiences at a low cost and simultaneously simulate an ‘interpersonal therapeutic component’ by targeting recipients (...) of screening process is more anonymous and may thus encourage participants to give information that is more honest. Interventions that are consistent and of high quality can be provided via computers, tablets, or smart phones (including using the internet) and can give information tailored to the individual participant ( ). Many computerized brief interventions consist of assessment, feedback and decision‐making modules. The assessment module aims to classify the user as either a low, medium, high

2017 Campbell Collaboration

59. SNMMI Procedure Standard for General Imaging 6.0

guidelines. III. DEFINITIONS A. Single Photon Scintillation Cameras provide static, dynamic or gated images of the distribution of radiopharmaceuticals within the body. Single photon emission computed tomographic (SPECT) images may be obtained by three dimensional reconstruction of a number of two dimensional planar images taken at different angles. B. Single Photon Emission Computed Tomography may be combined with Computed Tomography in a single system (SPECT/CT). C. Positron Cameras provide static (...) , dynamic or gated images of the distribution of positron-emitting radionuclides within the body by detecting pairs of photons produced in coincidence by the annihilation of a positron and an electron. Positron emission tomographic (PET) images are produced by reconstruction from the coincidence pair data. D. Positron Emission Tomography is generally combined with Computed Tomography in a single system (PET/CT). E. Nuclear Medicine Computer Systems collect, quantitate, analyze, and display the imaging

2018 Society of Nuclear Medicine and Molecular Imaging

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