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201. 3D Printed replica of articular fractures for surgical planning and patient consent: a two years multi-centric experience Full Text available with Trip Pro

3D Printed replica of articular fractures for surgical planning and patient consent: a two years multi-centric experience CT scanning with 3D reconstructed images are currently used to study articular fractures in orthopedic and trauma surgery. A 3D-Printer creates solid objects, starting from a 3D Computer representation.We report from two year of multicenter experience in 3D printing of articular fractures.During the study period, 102 patients (distal radius fractures, radial head, tibial

2016 3D Printing in Medicine

202. Three-Dimensional-Printing of Bio-Inspired Composites Full Text available with Trip Pro

researchers an excellent instrument to design and reconstruct natural-inspired materials. The most advanced 3D-printer can now be used to manufacture samples to emulate their geometry and material composition with high fidelity. Its capabilities, in combination with computational modeling, have provided us even more opportunities for designing, optimizing, and testing the function of composite materials, in order to achieve composites of high mechanical resilience and reliability. In this review article

2016 Journal of biomechanical engineering

203. A Protocol for Bioinspired Design: A Ground Sampler Based on Sea Urchin Jaws Full Text available with Trip Pro

observation, specimen characterization, device fabrication and mechanism bioexploration. The last step of bioexploration allows for a deeper understanding of the initial biology. The design architecture of the Aristotle's lantern is analyzed with micro-computed tomography and individual teeth are examined with scanning electron microscopy to identify the microstructure. Bioinspired designs are fabricated with a 3D printer, assembled and tested to determine the most efficient lantern opening and closing

2016 Journal of visualized experiments : JoVE

204. From tissue to silicon to plastic: three-dimensional printing in comparative anatomy and physiology Full Text available with Trip Pro

by reproduction on flat inherently 2D screens. One way to circumvent this problem is in the production of 3D-printed scale models. We have applied computed tomography and magnetic resonance imaging to produce digital models of animal anatomy well suited to be printed on low-cost 3D printers. In this communication, we report how to apply such technology in comparative anatomy and physiology to aid discovery, description, comprehension and communication, and we seek to inspire fellow researchers in these fields

2016 Royal Society Open Science

205. Low-cost Design and Manufacturing of Surgical Guides for Mandibular Reconstruction Using a Fibula Full Text available with Trip Pro

Low-cost Design and Manufacturing of Surgical Guides for Mandibular Reconstruction Using a Fibula Surgical cutting guides are used in mandibular reconstruction involving osteotomy of the mandible and fibula. Cutting guides produced using computer-aided design (CAD) and computer-aided manufacturing (CAM) technologies have been reported recently. These guides aim to increase the benefits to patients by improving the accuracy, shortening the operating time, and correcting occlusion. However (...) , the availability of these advanced technologies is limited in some regions of the world. To test whether we could produce low-cost surgical cutting guides, we made surgical guides and investigated their accuracy.Using free CAD software, we designed surgical cutting guides for the mandible and fibula and used these to perform virtual mandibular segmental osteotomies and fibula transplants in 12 model surgeries. The cutting guides were printed on a 3-dimensional (3D) printer. The model surgeries were performed

2016 Plastic and Reconstructive Surgery Global Open

206. Practical alignment method for X-ray spectral measurement in micro-CT system based on 3D printing technology Full Text available with Trip Pro

Practical alignment method for X-ray spectral measurement in micro-CT system based on 3D printing technology This study presents a practical alignment method for X-ray spectral measurement in a rotating gantry based micro-computed tomography (micro-CT) system using three-dimensional (3D) printing technology. In order to facilitate the spectrometer placement inside the gantry, supporting structures including a cover and a stand were dedicatedly designed and printed using a 3D printer. According

2016 Biomedical physics & engineering express

207. Macro-to-micro interfacing to microfluidic channels using 3D-printed templates: Application to time-resolved secretion sampling of endocrine tissue Full Text available with Trip Pro

fluidic reservoirs. We previously introduced the concept of using hand fabricated polymer inserts to template cell culture and sampling reservoirs into PDMS devices, allowing rapid stimulation and sampling of endocrine tissue. However, fabrication of the fluidic reservoirs was time consuming, tedious, and was prone to errors during device curing. Here, we have implemented computer-aided design and 3D printing to circumvent these fabrication obstacles. In addition to rapid prototyping and design (...) by temporally assaying glucose-stimulated insulin secretion from <10 pancreatic islets and glycerol secretion from 2 mm adipose tissue explants, suggesting that 3D-printed interface templates could be applicable to a variety of cells and tissue types. More generally, this work validates desktop 3D printers as versatile interfacing tools in microfluidic laboratories.

2016 The Analyst

208. Effect of Three-Dimensional Printed Personalized Moisture Chamber Spectacles on the Periocular Humidity Full Text available with Trip Pro

Effect of Three-Dimensional Printed Personalized Moisture Chamber Spectacles on the Periocular Humidity Purpose. To assess the effect of three-dimensional (3D) printed personalized moisture chamber spectacles (PMCS) on the periocular humidity. Methods. Facial computed tomography (CT) scanning was conducted on 10 normal subjects. PMCS was designed based on volume rendered CT images and produced using a 3D printer. Periocular humidity of PMCS and commercially available uniformed moisture chamber (...) spectacles (UMCS) were measured for 30 minutes via microhydrometer. Results. The mean ambient humidity was 15.76 ± 1.18%. The mean periocular humidity was 52.14 ± 3.00% in PMCS and 37.67 ± 8.97% in UMCS. The difference was significant (P < 0.001). Additionally, PMCS always demonstrated lower humidity than dew points. Conclusion. PMCS made by 3D printer provides appropriate fitness for the semiclosed humid chamber. PMCS showed higher performance than UMCS. The wearing of PMCS would be an effective method

2016 Journal of ophthalmology

209. Acquisition of 3D Facial Geometry of Patients' Scheduled for Radiotherapy Treatment

staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02930915 Locations Layout table for location information United Kingdom School of Computing Sciences, University of East Anglia Norwich, Norfolk, United Kingdom, NR4 7TJ Norfolk and Norwich Univeristy Hospital NHS foundation Trust Norwich, Norfolk, United Kingdom, NR47UY Sponsors and Collaborators University of East Anglia Clinical Research and Trials Unit (...) . B. Mortimore, D. Emmens, J. Patman, S. C. Short, and G. D. Bell. Towards the production of radiotherapy treatment shells on 3D printers using data derived from DICOM CT and MRI: preclinical feasibility studies. Journal of Radiotherapy in Practice 14, no. 01 (2015): 92-98. Layout table for additonal information Responsible Party: University of East Anglia ClinicalTrials.gov Identifier: Other Study ID Numbers: 82-03-16 First Posted: October 12, 2016 Last Update Posted: October 12, 2016 Last

2016 Clinical Trials

210. Application of 3D Printing Technique in Small Pulmonary Nodule Localization

was customized based on participant's computed tomography information. Participants received template-guided lung nodule localization. Device: template-guided localization Based on CT data, digital model of the navigational template was created using CAD software and imported to 3D printer. The navigational template serves as a guider to the localizer in lung nodule localization. Outcome Measures Go to Primary Outcome Measures : Accuracy of Lung Nodule Localization [ Time Frame: From the time of completing

2016 Clinical Trials

211. A Study Utilizing 3D Printing in Patients Undergoing External Beam Radiation Therapy

of conventional bolus preparation can be overcome by using a 3D printer. CT scans of the body can be used to create 3D models for boluses. The 3D models can then be printed into plastic boluses using a 3D printer. Preliminary studies have shown that 3D printed boluses conform to body contours better and allow for more precise control over radiation dose. In this study, both a conventional and 3D printed bolus will be made. The Investigators will then simulate treatment with both boluses to determine which (...) have been shown to create significant reduction in the surface dose. The goal of the present study is to improve the current process of bolus preparation by creating customized boluses with 3D printing. Customized boluses can be designed in Varian eclipse software and then imported into 3D modeling software such as 3D Slicer. The 3D model can then be converted into STL (Stereolithography) format which can be interpreted by the 3D printer software. Several preliminary studies have reported success

2016 Clinical Trials

212. 3D Geplante Osteosynthesen Mit Patientenspezifischen Zielvorrichtungen

by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: patient specific guides fracture fixation with 3D planning and use of patient-specific instruments Device: fracture fixation with patient specific guides Using the preoperative computed tomography scan, a 3D planning of the fracture Fixation is made and patient-specific guides for fracure fixation are produced using a 3D Printer. These Patient-specific guides are used for fracture fixation (...) : Balgrist University Hospital Collaborator: University of Zurich Information provided by (Responsible Party): Balgrist University Hospital Study Details Study Description Go to Brief Summary: Goal of this study is to evaluate the accuracy of 3D computer-planned fracture fixation with patient-specific instruments for clavicle, upper extremity, lower extremity and pelvis fractures compared with the standard procedure of fracture fixation. Condition or disease Intervention/treatment Phase Fracture

2016 Clinical Trials

213. Radiopaque Three-dimensional Printing: A Method to Create Realistic CT Phantoms. Full Text available with Trip Pro

, reproduction of patient anatomy was tested by printing computed tomographic (CT) images of a real patient abdomen scan. In a second step, gray scales, iodine deposition, and Hounsfield units were investigated by printing geometric phantoms with gray scales ranging from 0% (white) to 100% (black). On the basis of these results, a gray-scale-correction procedure was developed to achieve realistic Hounsfield units in the patient phantom. In a third step, reproduction of the real patient's Hounsfield units (...) template gray scales and printer deposition. Application of a correction procedure to the template gray scales allowed for a linear correlation (r = 0.9946; 95% confidence interval: 0.9916, 0.9966). After the same correction procedure was applied to the abdomen phantom, linear correlation of phantom and patient Hounsfield units was confirmed (r = 0.9925; 95% confidence interval: 0.9635, 0.9985). Conclusion The method presented in this work can realize realistic and customizable phantoms for diagnostic

2016 Radiology

214. Prescribing antipsychotics in primary care: new study highlights frequent off-label use

fully and where, theoretically, all prescriptions would have been generated electronically. From my own experience I know many prescriptions in primary care are prescribed via paper scripts on home visits or when the computer/printer/logon system isn’t working, relying on clinicians entering this information when they return to the practice or their technology returns to them, leaving room for missed information. Objective measurements were used and all subjects were classified into diagnostic

2015 The Mental Elf

215. Printed three-dimensional airway model assists planning of single-lung ventilation in a small child. Full Text available with Trip Pro

bronchial intubation on an anatomical model of her airway constructed from computed tomography (CT) data.We created a full-scale, anatomically accurate, transparent plastic model of the trachea and main bronchi on a three-dimensional printer using data from a CT scan. We then performed several different airway approaches to identify those likely to be most suitable, ex vivo, before the clinical procedure was carried out on the patient.The model helped us to choose the type and size of bronchial tubes

2015 British Journal of Anaesthesia

216. Preoperative surgical simulation of laparoscopic adrenalectomy for neuroblastoma using a three-dimensional printed model based on preoperative CT images. (Abstract)

Preoperative surgical simulation of laparoscopic adrenalectomy for neuroblastoma using a three-dimensional printed model based on preoperative CT images. Three-dimensional (3D) printed models based on computed tomography (CT) images facilitate the visualization of complex structures and are useful for understanding the surgical anatomy preoperatively. We developed a preoperative surgical simulation method using a 3D printed model based on CT images obtained prior to laparoscopic adrenalectomy (...) for adrenal neuroblastomas (NBs).The multi-detector CT images were transferred to a 3D workstation, and 3D volume data were obtained by reconstructing the sections. A model was made with a 3D printer using acrylic ultraviolet curable resin. The adrenal tumor, kidney, renal vein and artery, inferior vena cava, aorta, and outer body were fabricated. The pneumoperitoneum, insertion of trocars, and laparoscopic view were all attainable in this model. We used this model for three cases with adrenal NB.We used

2015 Journal of Pediatric Surgery

217. Antenatal Three-Dimensional Printing of Aberrant Facial Anatomy. Full Text available with Trip Pro

Antenatal Three-Dimensional Printing of Aberrant Facial Anatomy. Congenital airway obstruction poses a life-threatening challenge to the newborn. We present the first case of three-dimensional (3D) modeling and 3D printing of complex fetal maxillofacial anatomy after prenatal ultrasound indicated potential upper airway obstruction from a midline mass of the maxilla. Using fetal MRI and patient-specific computer-aided modeling, the craniofacial anatomy of the fetus was manufactured using a 3D (...) printer. This model demonstrated the mass to be isolated to the upper lip and maxilla, suggesting the oral airway to be patent. The decision was made to deliver the infant without a planned ex utero intrapartum treatment procedure. The neonate was born with a protuberant cleft lip and palate deformity, without airway obstruction, as predicted by the patient-specific model. The delivery was uneventful, and the child was discharged without need for airway intervention. This case demonstrates that 3D

2015 Pediatrics

218. Impact of the Virtual Human Project on Team-based Learning: A Randomized-controlled Trial

traditional small group learning models.1 Nevertheless, few studies have been published regarding the insertion of innovative audiovisual tools in the TBL context. The Virtual Human Project is described as powerful sequences of three dimension (3D) computer graphics video of the human body that aids learning by facilitating an understanding in relation to a specific subject. The Virtual Human is composed by video sequences combining anatomy, physiology, and morphology in the context of various diseases (...) . There are video sequences available for many disciplines, including dermatology and with capacity to produce anatomical structures by 3D printer. Despite the incredible potential applications of the Virtual Human, few studies have assessed its impact on medical education. The investigators did not find any study evaluating TBL with the insertion of iconographic educational material that assessed whether this intervention could change the learning progress of students. This is the aim of the present study

2015 Clinical Trials

219. Veteran Dual Use of Health Systems

health condition Prescribed 5 or more medications Upcoming VA and non-VA appointments within the study time frame Registered or willing to become registered with My HealtheVet Access to a computer with internet, phone, and a printer. English speaking VA or Non-VA Providers: provide care to a stuy participant Exclusion Criteria: Previously shared health data with a provider via their My HealtheVet or local provider patient portal No scheduled VA or non-VA appointments Contacts and Locations Go

2015 Clinical Trials

220. Click chemistry, 3D-printing, and omics: the future of drug development Full Text available with Trip Pro

therapy to each patient's complicated problem is a major challenge. One solution would be to match patients to existing compounds based on in silico modeling. However, optimization of complex therapy will eventually require designing compounds for patients using computer modeling and just-in-time production, perhaps achievable in the future by three-dimensional (3D) printing. Indeed, 3D printing is potentially transformative by virtue of its ability to rapidly generate almost limitless numbers (...) of objects that previously required manufacturing facilities. Companies are already endeavoring to develop affordable 3D printers for home use. An attractive, but as yet scantily explored, application is to place chemical design and production under digital control. This could be accomplished by utilizing a 3D printer to initiate chemical reactions, and print the reagents and/or the final compounds directly. Of interest, the Food and Drug Administration (FDA) has recently approved a 3D printed drug

2015 Oncotarget

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