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121. How can we be patient centered in the age of technology?

How can we be patient centered in the age of technology? How can we be patient centered in the age of technology? How can we be patient centered in the age of technology? | | January 15, 2018 132 Shares Four and a half years ago I read an editorial in JAMA, the Journal of the American Medical Association, that etched a short phrase into my memory. These five words seemed so profound and poignant that I really think they almost define primary care medicine today, perhaps with the alliterative (...) addition of the word “teach”. of how the computer had changed the dynamic in the exam room and of the communication skills physicians now need to master: The physician will know the highly technical vocabulary of relevant research agendas well enough to encourage patients to get involved. The physician will also keep up with popular culture, tracking popular direct-to-patient communications and incorporating them into the clinical dialogue. In addition, and most importantly, the physician will have

2018 KevinMD blog

122. COmparing CeNters ThRombectomy Aspiration STentretriever

COmparing CeNters ThRombectomy Aspiration STentretriever COmparing CeNters ThRombectomy Aspiration STentretriever - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. COmparing CeNters ThRombectomy Aspiration (...) Thrombectomy Study Design Go to Layout table for study information Study Type : Observational [Patient Registry] Estimated Enrollment : 1000 participants Observational Model: Cohort Time Perspective: Prospective Target Follow-Up Duration: 3 Years Official Title: COmparing CeNters ThRombectomy Aspiration STentretriever Actual Study Start Date : April 1, 2018 Estimated Primary Completion Date : March 1, 2021 Estimated Study Completion Date : June 1, 2021 Groups and Cohorts Go to Group/Cohort Intervention

2018 Clinical Trials

123. The interplay between bone and vessels in pediatric CKD: lessons from a single-center study. (PubMed)

The interplay between bone and vessels in pediatric CKD: lessons from a single-center study. Mineral and bone disorders associated to chronic kidney disease (CKD-MBD) are a daily challenge for pediatric nephrologists, with a significant risk of long-term bone and vascular comorbidities.This single-center study is a prospective transversal evaluation of pediatric CKD patients of our center, part of the European 4C study. In addition to clinical and biochemical data, vascular and bone evaluation (...) was performed: 24-h blood pressure assessment, carotid intima-media thickness (cIMT), pulse wave velocity (PWV), and high-resolution peripheral quantitative computed tomography (HR-pQCT) at the ultra-distal tibia. Results are presented as median (range).At a median age of 12.9 years (10.2-17.9), SDS height of - 1.0 (- 3.3-1.2) and estimated glomerular filtration rate (eGFR) of 33 mL/min/1.73m2 (11-72), 32 patients (8 girls) were evaluated. Median calcium, phosphate, parathyroid hormone (PTH), and 25 OHD3

2018 Pediatric Nephrology

124. Natural history and management of renal artery aneurysms in a single tertiary referral center. (PubMed)

Natural history and management of renal artery aneurysms in a single tertiary referral center. Although renal artery aneurysms (RAAs) are uncommon, several large reports have been published indicating their benign natural history. The objective of our study was to review our single-center experience managing this disease entity.A retrospective review of the Yale radiologic database from January 1999 to December 2016 was performed. Only patients with RAA and a computed tomography scan (...) of the abdomen were selected for review. Demographics of the patients, aneurysm characteristics, management, postoperative complications, and follow-up data were collected.There were 241 patients with 259 RAAs identified, with a mean age of 69 years (range, 35-100 years); 147 were female (61%). On computed tomography, aneurysms were solitary and right sided in 224 (86%) and 159 (61%), respectively; 64 (27%) patients had aneurysms elsewhere. The breakdown of RAAs by location was as follows: renal bifurcation

2018 Journal of Vascular Surgery

125. Developing a Shared Patient-Centered, Web-Based Medication Platform for Type 2 Diabetes Patients and Their Health Care Providers: Qualitative Study on User Requirements. (Full text)

Developing a Shared Patient-Centered, Web-Based Medication Platform for Type 2 Diabetes Patients and Their Health Care Providers: Qualitative Study on User Requirements. Information technology tools such as shared patient-centered, Web-based medication platforms hold promise to support safe medication use by strengthening patient participation, enhancing patients' knowledge, helping patients to improve self-management of their medications, and improving communication on medications among (...) patients and health care professionals (HCPs). However, the uptake of such platforms remains a challenge also due to inadequate user involvement in the development process. Employing a user-centered design (UCD) approach is therefore critical to ensure that user' adoption is optimal.The purpose of this study was to identify what patients with type 2 diabetes mellitus (T2DM) and their HCPs regard necessary requirements in terms of functionalities and usability of a shared patient-centered, Web-based

2018 Journal of medical Internet research PubMed

126. Natural history and management of splanchnic artery aneurysms in a single tertiary referral center. (PubMed)

Natural history and management of splanchnic artery aneurysms in a single tertiary referral center. Splanchnic artery aneurysms (SAAs) are rare, and little is known about their natural history and management. We reviewed our single-center experience in managing this population of patients.A retrospective review of the Yale radiologic database from January 1999 to December 2016 was performed. Only patients with an SAA and a computed tomography scan of the abdomen were selected for review (...) . Demographics of the patients, aneurysm characteristics, management, postoperative complications, and follow-up data were collected. Our primary outcomes included aneurysm growth rate and risk of rupture in those patients managed nonoperatively and morbidity and mortality of those SAA patients who underwent operative intervention.There were 122 patients with 138 SAAs identified; 77 were male (62%), with a mean age of 66 years (range, 25-94 years). On computed tomography, 56 (45%) had previously diagnosed

2018 Journal of Vascular Surgery

127. Localization of center of intramuscular nerve dense regions in adult anterior brachial muscles: a guide for botulinum toxin A injection to treat muscle spasticity (Full text)

Localization of center of intramuscular nerve dense regions in adult anterior brachial muscles: a guide for botulinum toxin A injection to treat muscle spasticity This study aimed to identify the location and depth of the center of intramuscular nerves dense regions (CINDRs) in anterior brachial muscles. Twelve adult cadavers were used. One side anterior brachial muscles were isolated and subjected to Sihler's staining to show intramuscular nerve dense regions. Then the data was used (...) to localize CINDRs in situ on the same muscles of the contralateral side. The localization method involved dissection and exposure of CINDRs, barium sulfate labeling, body surface reference line design, spiral computed tomography scan, three-dimensional image reconstruction, and Syngo system measurements. The number of CINDRs in coracobrachialis, biceps brachii and brachialis muscle were 3, 2 and 2, respectively. The body surface coordinates for the three CINDRs in coracobrachialis muscle were at 24.22

2018 American journal of translational research PubMed

128. Development of a Mobile Clinical Prediction Tool to Estimate Future Depression Severity and Guide Treatment in Primary Care: User-Centered Design (Full text)

remains challenging; however, mobile apps show promise in this respect. To increase the likelihood that an app-delivered clinical prediction tool can be successfully incorporated into clinical practice, it is important to involve end users in the app design process.The aim of the study was to maximize patient engagement in an app designed to improve treatment allocation for depression.An iterative, user-centered design process was employed. Qualitative data were collected via 2 focus groups (...) Development of a Mobile Clinical Prediction Tool to Estimate Future Depression Severity and Guide Treatment in Primary Care: User-Centered Design Around the world, depression is both under- and overtreated. The diamond clinical prediction tool was developed to assist with appropriate treatment allocation by estimating the 3-month prognosis among people with current depressive symptoms. Delivering clinical prediction tools in a way that will enhance their uptake in routine clinical practice

2018 JMIR mHealth and uHealth PubMed

129. Mining Electronic Health Records to Extract Patient-Centered Outcomes Following Prostate Cancer Treatment (Full text)

Mining Electronic Health Records to Extract Patient-Centered Outcomes Following Prostate Cancer Treatment The clinical, granular data in electronic health record (EHR) systems provide opportunities to improve patient care using informatics retrieval methods. However, it is well known that many methodological obstacles exist in accessing data within EHRs. In particular, clinical notes routinely stored in EHR are composed from narrative, highly unstructured and heterogeneous biomedical text (...) . This inherent complexity hinders the ability to perform automated large-scale medical knowledge extraction tasks without the use of computational linguistics methods. The aim of this work was to develop and validate a Natural Language Processing (NLP) pipeline to detect important patient-centered outcomes (PCOs) as interpreted and documented by clinicians in their dictated notes for male patients receiving treatment for localized prostate cancer at an academic medical center.

2018 AMIA Annual Symposium Proceedings PubMed

130. An Overview of Laryngeal Cancer Treatment at a Tertiary Care Oncological Center in a Developing Country (Full text)

An Overview of Laryngeal Cancer Treatment at a Tertiary Care Oncological Center in a Developing Country Introduction Development of laryngeal cancer is multifactorial, and management is surrounded with controversies. Recent reports suggest a decline in the survival of these patients. We conducted a study to analyze the clinicopathological parameters and compute the outcomes in terms of survival in patients with laryngeal cancer treated at our institution. Methods Electronic charts of 515 (...) patients with Laryngeal cancer treated at our Hospital and Research Center from 2004 to 2014 were retrospectively reviewed. Results Median age was 62 years. Male: female ratio 91%: 9%. Sixty-two percent were smokers. Histologically, all were squamous cell carcinoma. Most common subsite was glottis (88%). Treatment was non-surgical in 92% and surgical in 8%. The five-year overall survival (OS), disease-specific survival (DSS), disease-free survival (DFS) and locoregional control (LRC) were 67%, 74%, 59

2018 Cureus PubMed

131. A single-center experience of 100 image-guided video-assisted thoracoscopic surgery procedures (Full text)

collected data. Between October 2016 and January 2018, a total of 95 patients with 100 small lung nodules underwent iVATS. All procedures were performed in a hybrid operating room (HOR) in which a cone-beam computed tomography (CT) apparatus and a laser navigation system were present.The mean size of the 100 lung nodules was 7.94 mm, with their mean depth from the visceral pleura being 10 mm. A total of 98 nodules were successfully localized; of them, 94 were resected through a marker-guided procedure (...) A single-center experience of 100 image-guided video-assisted thoracoscopic surgery procedures The advent of image-guided video-assisted thoracoscopic surgery (iVATS) has allowed the simultaneous localization and removal of small lung nodules. The aim of this study is to detail, in a retrospective review, one institution's experience using iVATS in this clinical setting, with a special attention to efficacy, safety, and procedural details.This study was a retrospective analysis of prospectively

2018 Journal of thoracic disease PubMed

132. Prevalence of and factors associated with mammography and prostate-specific antigen screening among World Trade Center Health Registry enrollees, 2015–2016 (Full text)

Prevalence of and factors associated with mammography and prostate-specific antigen screening among World Trade Center Health Registry enrollees, 2015–2016 To compare the prevalence of mammography and prostate-specific antigen (PSA) testing in 9/11-exposed persons with the prevalence among the US population, and examine the association between 9/11 exposures and these screening tests using data from the World Trade Center Health Registry (WTCHR) cohort. We studied 8190 female and 13,440 male (...) enrollees aged ≥40 years at survey completion (2015-2016), who had a medical visit during the preceding year, had no self-reported breast or prostate cancer, and did not have screening for non-routine purposes. We computed age-specific prevalence of mammography (among women) and PSA testing (among men), and compared to the general population using 2015 National Health Interview Survey data (NHIS). We also computed the adjusted prevalence ratio (PR) and 95% confidence interval (95% CI) to examine

2018 Preventive medicine reports PubMed

133. Compressive Sensing Based Multilevel Fast Multipole Acceleration for Fast Scattering Center Extraction and ISAR Imaging (Full text)

) scattering problem over a wide incident angle. This allows composition of a new kind of incident wave, which obtains efficient and reliable data for scattering centers extraction with low complexity. The resulting data from CS-based MLFMA are processed for ISAR) imaging. Simulation results show the received data for ISAR imaging from MLFMA with CS can outperform the data from MLFMA, which achieves a similar quality of ISAR imaging. Additionally, the computation complexity is improved by CS through (...) Compressive Sensing Based Multilevel Fast Multipole Acceleration for Fast Scattering Center Extraction and ISAR Imaging In recent years, Compressive Sensing (CS) theory has been very popular in the data sensing and process area as it utilizes the sparsity and measurement matrix to reconstruct the compressible signal from limited samples successfully. In this paper, CS is introduced into an efficient numerical method, multilevel fast multipole acceleration (MLFMA), for the electromagnetic (EM

2018 Sensors (Basel, Switzerland) PubMed

134. Patient-Centered Communication of Life Expectancy Estimates in Genitourinary Malignancies

and Charlson comorbidity score cutoffs (1,2), and life expectancy for bladder cancer patients will be determined using definitions as noted by Cho et al (3). Talking points will be provided to counseling physicians on how to meaningfully communicate life expectancy data. Subjects will also complete a computer-based conjoint analysis exercise prior to the counseling visit; results will be used to help physicians understand how the subject values life expectancy compared with other decision attributes (4 (...) conjoint analysis exercise prior to counseling. Behavioral: Patient-centered communication of life expectancy The intervention arm will test if patient-specific LE estimates via a targeted, patient-centered communication approach paired with LE-specific conjoint analysis data improves decisional conflict, quality of LE discussion, and reduces rates of overtreatment of Genitourinary malignancies. No Intervention: Standard-of-care Arm Patients in the standard-of-care arm will not receive an intervention

2018 Clinical Trials

135. Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease

Party: Robert Cronin, Assistant Professor, Vanderbilt University Medical Center ClinicalTrials.gov Identifier: Other Study ID Numbers: K23HL141447-2 First Posted: August 14, 2018 Last Update Posted: August 15, 2018 Last Verified: August 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Robert Cronin, Vanderbilt (...) Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2018 Clinical Trials

136. Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 3)

Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 3) Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 3) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Integrating (...) Mindfulness Into the Patient-Centered Medical Home (Phase 3) (MINDFUL-PC-3) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03609450 Recruitment Status : Recruiting First Posted : August 1, 2018 Last Update Posted : February 4

2018 Clinical Trials

137. Prospective Single Center Randomized Double Blind Controlled Tolerability Trial of Six Hair Cleansing Conditioners

the six hair cleansing products will be dispensed. Treatment site allocation will be determined by a computer-generated randomization log. Primary Purpose: Other Official Title: Prospective Single Center Randomized Double Blind Controlled Tolerability Trial of Six Hair Cleansing Conditioners Actual Study Start Date : April 4, 2018 Actual Primary Completion Date : December 14, 2018 Actual Study Completion Date : December 14, 2018 Arms and Interventions Go to Arm Intervention/treatment Hair Cleansing (...) Prospective Single Center Randomized Double Blind Controlled Tolerability Trial of Six Hair Cleansing Conditioners Prospective Single Center Randomized Double Blind Controlled Tolerability Trial of Six Hair Cleansing Conditioners - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2018 Clinical Trials

138. Diagnostic Significance of Single Center, Open and Prospective Evaluation of <Sup>18<Sup>F-FDG PET/CT Dynamic Imaging and Genomic Sequencing in Detecting Metastatic Lesions of Primary Hepatocellular Carcinoma

Diagnostic Significance of Single Center, Open and Prospective Evaluation of 18F-FDG PET/CT Dynamic Imaging and Genomic Sequencing in Detecting Metastatic Lesions of Primary Hepatocellular Carcinoma Diagnostic Significance of Single Center, Open and Prospective Evaluation of 18F-FDG PET/CT Dynamic Imaging and Genomic Sequencing in Detecting Metastatic Lesions of Primary Hepatocellular Carcinoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record (...) managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Diagnostic Significance of Single Center, Open and Prospective Evaluation of 18F-FDG PET/CT Dynamic Imaging and Genomic Sequencing in Detecting Metastatic Lesions of Primary Hepatocellular Carcinoma The safety and scientific

2018 Clinical Trials

139. Reference-point centering and range-adaptation enhance human reinforcement learning at the cost of irrational preferences (Full text)

Reference-point centering and range-adaptation enhance human reinforcement learning at the cost of irrational preferences In economics and perceptual decision-making contextual effects are well documented, where decision weights are adjusted as a function of the distribution of stimuli. Yet, in reinforcement learning literature whether and how contextual information pertaining to decision states is integrated in learning algorithms has received comparably little attention. Here, we investigate (...) reinforcement learning behavior and its computational substrates in a task where we orthogonally manipulate outcome valence and magnitude, resulting in systematic variations in state-values. Model comparison indicates that subjects' behavior is best accounted for by an algorithm which includes both reference point-dependence and range-adaptation-two crucial features of state-dependent valuation. In addition, we find that state-dependent outcome valuation progressively emerges, is favored by increasing

2018 Nature communications PubMed

140. Biobank integration of large-scale clinical and histopathology melanoma studies within the European Cancer Moonshot Lund Center (Full text)

Biobank integration of large-scale clinical and histopathology melanoma studies within the European Cancer Moonshot Lund Center We present the Cancer Moonshot clinical project located at the European center in Lund. Here, tissue and blood samples have been collected and stored in a large-scale biobank. Multiple clinical centers around the world are participating and tissue and blood samples are sent to the European Cancer Moonshot Lund Center that acts as the clinical hub. Our center has been (...) developed to generate and build large-scale biostorage archives of patient melanoma samples, which is then combined with a histopathological capability to characterize the patient tumours. Such a large-scale clinical sample processing initiative has begun with the aim of creating high-end histopathology indexing with database computational power and including proteogenomic analysis. The biobank at Lund has become an important resource in clinical research worldwide. Following suite, several national

2018 Clinical and translational medicine PubMed

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