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81. The Cardiovascular Trial of the Testosterone Trials: rationale, design, and baseline data of a clinical trial using computed tomographic imaging to assess the progression of coronary atherosclerosis. Full Text available with Trip Pro

The Cardiovascular Trial of the Testosterone Trials: rationale, design, and baseline data of a clinical trial using computed tomographic imaging to assess the progression of coronary atherosclerosis. Data from prior studies have yielded inconsistent results on the association of serum testosterone levels with the risk for cardiovascular disease. There are no clinical trial data on the effects of testosterone replacement therapy on plaque progression.We designed a study to investigate the effect (...) of testosterone therapy on coronary artery plaque progression using serial coronary computed tomographic angiography (CCTA). In this paper, we describe the study design, methods, and characteristics of the study population.The Cardiovascular Trial of the Testosterone Trials (TTrials; NCT00799617) is a double-blind, placebo-controlled trial of 1 year of testosterone therapy in men 65 years or older with clinical manifestations of androgen deficiency and unequivocally low serum testosterone concentrations (<275

2015 Coronary artery disease Controlled trial quality: predicted high

82. 2018 EHRA Expert Consensus Statement on Lead Extraction: Recommendations on Definitions, Endpoints, Research Trial Design, and Data Collection Requirements for Clinical Scientific Studies and Registries: Endorsed by APHRS/HRS/LAHRS

2018 EHRA Expert Consensus Statement on Lead Extraction: Recommendations on Definitions, Endpoints, Research Trial Design, and Data Collection Requirements for Clinical Scientific Studies and Registries: Endorsed by APHRS/HRS/LAHRS 2018EHRAexpertconsensusstatementon leadextraction:recommendationson definitions,endpoints,researchtrialdesign, anddatacollectionrequirementsforclinical scientificstudiesandregistries:endorsed byAPHRS/HRS/LAHRS MariaG.Bongiorni(Chair) 1 *,HaranBurri(Co-chair) 2 (...) ,andClaudiodeZuloaga 27 1 Department of Cardiology, University Hospital of Pisa, Pisa, Italy; 2 Department of Cardiology, University Hospital of Geneva, Geneva, Switzerland; 3 Department of Cardiology, CHU la Timone, Marseilles, France; 4 Department of Cardiothoracic and Vascular Surgery, German Heart Institute Berlin, Berlin, Germany; 5 Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden; 6 Electrophysiology Division, 2nd Department of Medicine and Cardiology Center

2018 Heart Rhythm Society

83. Dynamic Voltage Frequency Scaling Simulator for Real Workflows Energy-Aware Management in Green Cloud Computing. Full Text available with Trip Pro

Dynamic Voltage Frequency Scaling Simulator for Real Workflows Energy-Aware Management in Green Cloud Computing. Nowadays, the growing computational capabilities of Cloud systems rely on the reduction of the consumed power of their data centers to make them sustainable and economically profitable. The efficient management of computing resources is at the heart of any energy-aware data center and of special relevance is the adaptation of its performance to workload. Intensive computing (...) and time saving are presented. Also, results achieved by the intra-host DVFS strategy with different governors are compared to those of the data center using a recent and successful DVFS-based inter-host scheduling strategy as overlapped mechanism to the DVFS intra-host technique.

2017 PLoS ONE

84. Quality improvement of functional diagnostics in dentistry through computer-aided diagnosis: a randomized controlled trial. (Abstract)

) in this study investigated whether computer-aided diagnosis (CADx) of temporomandibular disorders (TMD) offers quality advantages over traditional diagnosis (TRAD).Thirty-nine 5th-year dental students (examiners) at a university in Hamburg, Germany, received joint training in the diagnosis of TMD by clinical functional analysis and manual structural analysis ('orthopedic tests'). This study is based on anonymized data from 10 patients who were consecutively recruited at a specialized TMJ treatment center (...) Quality improvement of functional diagnostics in dentistry through computer-aided diagnosis: a randomized controlled trial. Functional diagnostic examinations such as clinical functional analysis and manual structural analysis ('orthopedic tests') allow the dentist to establish a structured diagnosis. Previously, the process of correlating findings with the appropriate diagnoses was guided by human thought processes alone. The experimental diagnostic randomized controlled trial (RCT

2018 International journal of computerized dentistry Controlled trial quality: uncertain

85. Does patient time spent viewing computer-tailored colorectal cancer screening materials predict patient-reported discussion of screening with providers? Full Text available with Trip Pro

Does patient time spent viewing computer-tailored colorectal cancer screening materials predict patient-reported discussion of screening with providers? The main aim is to examine whether patients' viewing time on information about colorectal cancer (CRC) screening before a primary care physician (PCP) visit is associated with discussion of screening options during the visit. We analyzed data from a multi-center randomized controlled trial of a tailored interactive multimedia computer program

2018 Health education research Controlled trial quality: uncertain

86. Computed Tomography (CT) Guided Lung Biopsy With Plug

Computed Tomography (CT) Guided Lung Biopsy With Plug Computed Tomography (CT) Guided Lung Biopsy With Plug - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Computed Tomography (CT) Guided Lung Biopsy (...) by (Responsible Party): Haseem Ashraf, University Hospital, Akershus Study Details Study Description Go to Brief Summary: Protocol Title: Computed Tomography (CT) Guided Lung Biopsy with BioSentry Plug, Evaluation of Safety and Efficacy. Condition or disease Intervention/treatment Phase Computed Tomography, Biopsy, Pneumothorax, Chest Tube, Plug Device: The BioSentry Tract Sealant System Not Applicable Detailed Description: Protocol Summary: Prospective, randomized, controlled, unblinded, post-market, single

2018 Clinical Trials

87. Preparative Fasting Before Contrast-enhanced Computed Tomography

Center, Israel Information provided by (Responsible Party): Naiel Bisharat, HaEmek Medical Center, Israel Study Details Study Description Go to Brief Summary: The study aims to determine whether there is a need for preparative fasting prior to contrast-enhanced computed tomography (CT). Condition or disease X-ray Contrast Media Adverse Reaction Detailed Description: The use of fasting orders for imaging and other procedures is common, this seemingly benign practice can lead to real harms to patients (...) Preparative Fasting Before Contrast-enhanced Computed Tomography Preparative Fasting Before Contrast-enhanced Computed Tomography - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Preparative Fasting Before

2018 Clinical Trials

88. Computed Tomography Angiography Prediction Score for Side Branch Occlusion

. The CT-PRECISION (Computed Tomography angiography PREdiCtIon score for SIde branch Occlusion in coronary bifurcation interventioN) registry was designed to evaluate the application of coronary computed tomography angiography (coronary CTA) for the prediction of SB occlusion during percutaneous revascularization of bifurcation lesions. The main purpose of this single-center study is to develop a noninvasive CTA-based prediction tool to determine the procedural outcome of PCI in bifurcation lesions (...) Computed Tomography Angiography Prediction Score for Side Branch Occlusion Computed Tomography Angiography Prediction Score for Side Branch Occlusion - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Computed

2018 Clinical Trials

89. Comparison of Computer-Assisted Navigation and Conventional Instrumentation for Bilateral Total Knee Arthroplasty

, 2018 Last Update Posted : September 13, 2018 Sponsor: Chang Gung Memorial Hospital Information provided by (Responsible Party): Chang Gung Memorial Hospital Study Details Study Description Go to Brief Summary: To compare the functional outcomes of Computer-Assisted Navigation (CAS) and Conventional Instrumentation TKA at the 8-year follow-up. Condition or disease Intervention/treatment Arthropathy of Knee Joint Procedure: Computer-Assisted Navigation TKA Detailed Description: The data (...) , lateral radiographs of the knee and standing long-leg radiographs of the lower extremity were obtained pre- and postoperatively. The lower extremities were fully extended so that the tibial tuberosities were facing forward and the lateral malleoli were 15 cm apart to ensure that the tibia was vertical and facing forward with minimal rotation. The X-ray beam (20-25 mA/s; 80-85 kV) was centered at the knee joint level at a distance of 120-140 cm.Radiographic data included the mechanical axis angle

2018 Clinical Trials

90. Evaluation of Fractional Flow Reserve Calculated by Computed Tomography Coronary Angiography in Patients Undergoing TAVR

valve stenosis. Condition or disease Intervention/treatment Phase Aortic Valve Stenosis Coronary Artery Disease Device: iFR / FFR measurement Not Applicable Detailed Description: This is a single-center, open-label, exploratory, prospective study. Among patients who undergo coronary computed tomography angiography (cCTA) prior to TAVR, those with moderate or severe stenotic lesions will be included in the study. Patients from whom consent is obtained following TAVR will be enrolled in the study (...) : None (Open Label) Primary Purpose: Diagnostic Official Title: Evaluation of Fractional Flow Reserve Calculated by Computed Tomography Coronary Angiography in Patients Undergoing Transcatheter Aortic Valve Replacement(FORTUNA): Single Center, Open-label, Exploratory, Prospective Study Estimated Study Start Date : September 13, 2018 Estimated Primary Completion Date : March 31, 2022 Estimated Study Completion Date : March 31, 2022 Resource links provided by the National Library of Medicine related

2018 Clinical Trials

91. Blunt Trauma Abdominal and Pelvic Computed Tomography Has Low Yield for Injuries in More Than One Anatomic Region Full Text available with Trip Pro

Blunt Trauma Abdominal and Pelvic Computed Tomography Has Low Yield for Injuries in More Than One Anatomic Region Most trauma centers order abdominal and pelvic computed tomography (CT) as an automatically paired CT for adult blunt trauma evaluation. However, excessive CT utilization adds risks of excessive exposure to ionizing radiation, the need to work up incidental findings (leading to unnecessary and invasive tests), and greater costs. Examining a cohort of adult blunt trauma patients (...) assessments at an urban Level I trauma center from April through October 2014. Categorization of CSI was determined according to an a priori, expert panel-derived classification scheme.The median age of the 689 patients who had A/P CT was 48 years old; 68.1% were male; 64.0% were admitted, and hospital mortality was 3.6%. CSI yields were as follows: abdomen 2.2% (95% confidence interval [CI] [1.3-3.6%]); pelvis 2.9% (95% CI [1.9-4.4%]); lumbosacral spine 0.6% (95% CI [0.2-1.5%]); both abdomen and pelvis

2018 Western Journal of Emergency Medicine

92. Adaptive responses of sterically confined intramolecular chalcogen bonds †Electronic supplementary information (ESI) available: Computational details and coordinates. See DOI: 10.1039/c8sc01943f Full Text available with Trip Pro

Adaptive responses of sterically confined intramolecular chalcogen bonds †Electronic supplementary information (ESI) available: Computational details and coordinates. See DOI: 10.1039/c8sc01943f The responsive behavior of an entity towards its immediate surrounding is referred to as an adaptive response. The adaptive responses of a noncovalent interaction at the molecular scale are reflected from its structural and functional roles. Intramolecular chalcogen bonding (IChB), an attractive (...) interaction between a heavy chalcogen E (E = Se or Te) centered sigma hole and an ortho-heteroatom Lewis base donor D (D = O or N), plays an adaptive role in defining the structure and reactivity of arylchalcogen compounds. In this perspective, we describe the adaptive roles of a chalcogen centered Lewis acid sigma hole and a proximal Lewis base (O or N) in accommodating built-in steric stress in 2,6-disubstituted arylchalcogen compounds. From our perspective, the IChB components (a sigma hole

2018 Chemical Science

93. Evaluation of the diagnostic accuracy of Computer-Aided Detection of tuberculosis on Chest radiography among private sector patients in Pakistan Full Text available with Trip Pro

retrospective data from CAD4TB and Xpert MTB/RIF testing carried out at two private TB treatment and diagnostic centers in Karachi. Sensitivity, specificity, potential Xperts saved, were computed and the receiver operator characteristic curves were constructed for four different models of CAD4TB. A total of 6,845 individuals with presumptive TB were enrolled in the study, 15.2% of which had MTB + ve result on Xpert. A high sensitivity (range 65.8-97.3%) and NPV (range 93.1-98.4%) were recorded for CAD4TB (...) Evaluation of the diagnostic accuracy of Computer-Aided Detection of tuberculosis on Chest radiography among private sector patients in Pakistan The introduction of digital CXR with automated computer-aided interpretation, has given impetus to the role of CXR in TB screening, particularly in low resource, high-burden settings. The aim of this study was to evaluate the diagnostic accuracy of CAD4TB as a screening tool, implemented in the private sector in Karachi, Pakistan. This study analyzed

2018 Scientific reports

94. qCon: QoS-Aware Network Resource Management for Fog Computing Full Text available with Trip Pro

qCon: QoS-Aware Network Resource Management for Fog Computing Fog computing is a new computing paradigm that employs computation and network resources at the edge of a network to build small clouds, which perform as small data centers. In fog computing, lightweight virtualization (e.g., containers) has been widely used to achieve low overhead for performance-limited fog devices such as WiFi access points (APs) and set-top boxes. Unfortunately, containers have a weakness in the control (...) of network bandwidth for outbound traffic, which poses a challenge to fog computing. Existing solutions for containers fail to achieve desirable network bandwidth control, which causes bandwidth-sensitive applications to suffer unacceptable network performance. In this paper, we propose qCon, which is a QoS-aware network resource management framework for containers to limit the rate of outbound traffic in fog computing. qCon aims to provide both proportional share scheduling and bandwidth shaping

2018 Sensors (Basel, Switzerland)

95. Geographic Availability of Low-Dose Computed Tomography for Lung Cancer Screening in the United States, 2017 Full Text available with Trip Pro

JC Lung Cancer Alliance, Washington, DC. eng T32 GM081740 GM NIGMS NIH HHS United States Journal Article Research Support, N.I.H., Extramural 2018 10 04 United States Prev Chronic Dis 101205018 1545-1151 IM Aged Early Detection of Cancer Female Healthcare Disparities statistics & numerical data Humans Lung Neoplasms diagnosis mortality Male Mass Screening standards statistics & numerical data Middle Aged Radiation Dosage Tomography, X-Ray Computed statistics & numerical data United States 2018 10 (...) Geographic Availability of Low-Dose Computed Tomography for Lung Cancer Screening in the United States, 2017 30289107 2019 02 21 2019 02 21 1545-1151 15 2018 10 04 Preventing chronic disease Prev Chronic Dis Geographic Availability of Low-Dose Computed Tomography for Lung Cancer Screening in the United States, 2017. E119 10.5888/pcd15.180241 Eberth Jan M JM Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, 29208. Email

2018 Preventing chronic disease

96. Privacy-preserving record linkage in large databases using secure multiparty computation Full Text available with Trip Pro

Privacy-preserving record linkage in large databases using secure multiparty computation Practical applications for data analysis may require combining multiple databases belonging to different owners, such as health centers. The analysis should be performed without violating privacy of neither the centers themselves, nor the patients whose records these centers store. To avoid biased analysis results, it may be important to remove duplicate records among the centers, so that each patient's (...) data would be taken into account only once. This task is very closely related to privacy-preserving record linkage.This paper presents a solution to privacy-preserving deduplication among records of several databases using secure multiparty computation. It is build upon one of the fastest practical secure multiparty computation platforms, called Sharemind.The tests on ca 10 million records of simulated databases with 1000 health centers of 10000 records each show that the computation is feasible

2018 BMC medical genomics

97. Role of intellectual capital on creation of innovation capabilities in HIS and computer units Full Text available with Trip Pro

during 2015.The present study seeks to evaluate the impact of different aspects of intellectual property on innovations in computer and HIS units at selected medical centers in the city of Isfahan during 2015 (2015).Population of this research includes staff working in computer and HIS units of 10 medical centers. Data were collected using a questionnaire made by the researcher. A written questionnaire (also referred to as self-administered questionnaire) is a data collection tool in which written (...) the base of economy in today's world. In today's knowledge-based economy, production and exploitation of knowledge play the main roles in the process of wealth creation. Considering key contributions of knowledge management in competitiveness of organizations and their entry into global arenas, this study sought to evaluate the impact of different aspects of intellectual property on innovations in computer and health information system (HIS) units at selected medical center in the city of Isfahan

2018 Journal of education and health promotion

98. Towards Portable Large-Scale Image Processing with High-Performance Computing Full Text available with Trip Pro

Towards Portable Large-Scale Image Processing with High-Performance Computing High-throughput, large-scale medical image computing demands tight integration of high-performance computing (HPC) infrastructure for data storage, job distribution, and image processing. The Vanderbilt University Institute for Imaging Science (VUIIS) Center for Computational Imaging (CCI) has constructed a large-scale image storage and processing infrastructure that is composed of (1) a large-scale image database (...) using the eXtensible Neuroimaging Archive Toolkit (XNAT), (2) a content-aware job scheduling platform using the Distributed Automation for XNAT pipeline automation tool (DAX), and (3) a wide variety of encapsulated image processing pipelines called "spiders." The VUIIS CCI medical image data storage and processing infrastructure have housed and processed nearly half-million medical image volumes with Vanderbilt Advanced Computing Center for Research and Education (ACCRE), which is the HPC facility

2018 Journal of Digital Imaging

99. Residential Consumer-Centric Demand-Side Management Based on Energy Disaggregation-Piloting Constrained Swarm Intelligence: Towards Edge Computing Full Text available with Trip Pro

computing—a method of optimizing cloud computing technologies by driving computing capabilities at the IoT edge of the Internet as one of the emerging trends in engineering technology—addresses bandwidth-intensive contents and latency-sensitive applications required among sensors and central data centers through data analytics at or near the source of data. A non-intrusive load-monitoring technique proposed previously is utilized to automatic determination of physical characteristics (...) Residential Consumer-Centric Demand-Side Management Based on Energy Disaggregation-Piloting Constrained Swarm Intelligence: Towards Edge Computing The emergence of smart Internet of Things (IoT) devices has highly favored the realization of smart homes in a down-stream sector of a smart grid. The underlying objective of Demand Response (DR) schemes is to actively engage customers to modify their energy consumption on domestic appliances in response to pricing signals. Domestic appliance

2018 Sensors (Basel, Switzerland)

100. Computed tomographic appearance of abdominal lymph nodes in healthy cats Full Text available with Trip Pro

Computed tomographic appearance of abdominal lymph nodes in healthy cats Computed tomography (CT) is commonly used in veterinary medicine and plays an important role in disease identification and cancer staging. Identification of abnormal abdominal lymph nodes is important for clinical, therapeutic, and prognostic decision making. No published study describes the CT appearance of abdominal lymph nodes in healthy cats.All abdominal lymph centers will be identified on CT with the majority (...) , and pancreaticoduodenal lymph nodes identified in 16/16 cats. Lymph node size and shape varied among lymph centers with nearly all lymph nodes homogeneously contrast enhancing in 515/525. Significant negative correlations were identified between age and length (P = .0166) and width (P = .0387) of abdominal lymph nodes as well as age and number of sacral lymph nodes (P = .0493). Intranodal fat was present in 18/525 lymph nodes.CT readily permitted identification and characterization of feline abdominal lymph nodes

2018 Journal of Veterinary Internal Medicine

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