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61. Application of speCtraL Computed tomogrAphy to impRove specIficity of Cardiac compuTed tomographY

Application of speCtraL Computed tomogrAphy to impRove specIficity of Cardiac compuTed tomographY Application of speCtraL Computed tomogrAphy to impRove specIficity of Cardiac compuTed tomographY - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Application of speCtraL Computed tomogrAphy to impRove specIficity of Cardiac compuTed tomographY (CLARITY) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03139006 Recruitment

2017 Clinical Trials

62. Comparison between computed tomography‐guided percutaneous microwave ablation and thoracoscopic lobectomy for stage I non‐small cell lung cancer (PubMed)

Comparison between computed tomography‐guided percutaneous microwave ablation and thoracoscopic lobectomy for stage I non‐small cell lung cancer The study was conducted to investigate the effectiveness and cost of computed tomography (CT)-guided percutaneous microwave ablation (MWA) and thoracoscopic lobectomy for stage I non-small cell lung cancer (NSCLC).We retrospectively analyzed the data of 46 and 85 patients with stage I NSCLC treated with CT-guided percutaneous MWA or thoracoscopic (...) lobectomy, respectively, at our center from July 2013 to June 2015. Overall survival (OS), disease-free survival (DFS), local control rate, hospital stay, and cost were evaluated. Survival curves were constructed using the Kaplan-Meier method and compared using the log-rank test.The one and two-year OS rates were 97.82% and 91.30% and 97.65% and 90.59% in the MWA and lobectomy groups, respectively. The one and two-year DFS rates were 95.65% and 76.09% and 95.29% and 75.29%, respectively. No significant

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2018 Thoracic cancer

63. Democratizing data science through data science training (PubMed)

Training Coordinating Center (TCC; bigdatau.org) was funded to facilitate both in-person and online learning, and open up the concepts of data science to the widest possible audience. Here, we describe the activities of the BD2K TCC and its focus on the construction of the Educational Resource Discovery Index (ERuDIte), which identifies, collects, describes, and organizes online data science materials from BD2K awardees, open online courses, and videos from scientific lectures and tutorials. ERuDIte (...) now indexes over 9,500 resources. Given the richness of online training materials and the constant evolution of biomedical data science, computational methods applying information retrieval, natural language processing, and machine learning techniques are required - in effect, using data science to inform training in data science. In so doing, the TCC seeks to democratize novel insights and discoveries brought forth via large-scale data science training.

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2018 Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

64. DataPackageR: Reproducible data preprocessing, standardization and sharing using R/Bioconductor for collaborative data analysis (PubMed)

sized teams of computational scientists. Our primary contribution is the DataPackageR tool, which decouples time-consuming data processing from data analysis while leaving a traceable record of how raw data is processed into analysis-ready data sets. The software ensures packaged data objects are properly documented and performs checksum verification of these along with basic package version management, and importantly, leaves a record of data processing code in the form of package vignettes. Our (...) group has implemented this work-flow to manage, analyze and report on pre-clinical immunological trial data from multi-center, multi-assay studies for the past three years.

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2018 Gates Open Research

65. Clinical epidemiological survey of gallbladder carcinoma in northwestern China, 2009–2013: 2379 cases in 17 centers (PubMed)

Clinical epidemiological survey of gallbladder carcinoma in northwestern China, 2009–2013: 2379 cases in 17 centers To analyze the clinical epidemiological characteristics of patients with gallbladder carcinoma recruited from 17 hospitals in five northwestern provinces of China (Shaanxi Province, Gansu Province, Qinghai Province, Ningxia Hui Autonomous Region, and Xinjiang Uygur Autonomous Region) from 2009 to 2013, and to summarize the clinical diagnosis and treatment data of gallbladder (...) positive in those receiving B ultrasound examinations and 90.7% (1567/1727) were positive in those undergoing computed tomography, and 64.5% (1124/1742) of patients with gallbladder carcinoma were positive for carbohydrate antigen (CA) 19-9. (5) The pathological type of gallbladder carcinoma was mainly moderately and poorly differentiated adenocarcinoma with a high degree of malignancy. At admission, 55.1% (1091/1981) of patients had stage IV cancer among patients with TNM staging information; 55.9

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2017 Chronic diseases and translational medicine

66. Cost of Providing Quality Cancer Care at the Butaro Cancer Center of Excellence in Rwanda (PubMed)

Cost of Providing Quality Cancer Care at the Butaro Cancer Center of Excellence in Rwanda The cost of providing cancer care in low-income countries remains largely unknown, which creates a significant barrier to effective planning and resource allocation. This study examines the cost of providing comprehensive cancer care at the Butaro Cancer Center of Excellence (BCCOE) in Rwanda.A retrospective costing analysis was conducted from the provider perspective by using secondary data from (...) . Radiotherapy services, which require sending patients out of country because there are no radiation units in Rwanda, comprised 25% of program costs, labor accounted for 21%, and chemotherapy, supportive medications, and consumables accounted for 15%. Overhead, training, computed tomography scans, surgeries, blood products, pathology, and social services accounted for less than 10% of the total.This study is one of the first to examine operating costs for implementing a cancer center in a low-income country

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2017 Journal of global oncology

67. The use of whole body computed tomography scans in pediatric trauma patients: Are there differences among adults and pediatric centers? (PubMed)

The use of whole body computed tomography scans in pediatric trauma patients: Are there differences among adults and pediatric centers? Whole body CT (WBCT) scan is known to be associated with significant radiation risk especially in pediatric trauma patients. The aim of this study was to assess the use WBCT scan across trauma centers for the management of pediatric trauma patients.We performed a two year (2011-2012) retrospective analysis of the National Trauma Data Bank. Pediatric (age (...) ≤18years) trauma patients managed in level I or II adult or pediatric trauma centers with a head, neck, thoracic, or abdominal CT scan were included. WBCT scan was defined as CT scan of the head, neck, thorax, and abdomen. Patients were stratified into two groups: patients managed in adult centers and patients managed in designated pediatric centers. Outcome measure was use of WBCT. Multivariate logistic regression analysis was performed.A total of 30,667 pediatric trauma patients were included

2015 Journal of Pediatric Surgery

68. Comparative Analysis of Canal Centering Ability of Different Single File Systems Using Cone Beam Computed Tomography- An In-Vitro Study (PubMed)

Comparative Analysis of Canal Centering Ability of Different Single File Systems Using Cone Beam Computed Tomography- An In-Vitro Study The ability of an endodontic instrument to remain centered in the root canal system is one of the most important characteristic influencing the clinical performance of a particular file system. Thus, it is important to assess the canal centering ability of newly introduced single file systems before they can be considered a viable replacement of full-sequence (...) rotary file systems.The aim of the study was to compare the canal transportation, centering ability, and time taken for preparation of curved root canals after instrumentation with single file systems One Shape and Wave One, using cone-beam computed tomography (CBCT).Sixty mesiobuccal canals of mandibular molars with an angle of curvature ranging from 20(o) to 35(o) were divided into three groups of 20 samples each: ProTaper PT (group I) - full-sequence rotary control group, OneShape OS (group II

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2015 Journal of clinical and diagnostic research : JCDR

69. 30 yo woman with chest pain and a "normal ECG" by the computer, this one prehospital

30 yo woman with chest pain and a "normal ECG" by the computer, this one prehospital Dr. Smith's ECG Blog: 30 yo woman with chest pain and a "normal ECG" by the computer, this one prehospital Saturday, September 30, 2017 This was sent by paramedics in the Northwest Ambulance Service in the UK. James Alameddine credits his partner, Gary Wilson. Case A 30 year old woman complained of chest pain and called 911. She had a prehospital 12-lead ECG recorded: As you can see, the computer interpretation (...) is "normal" What do you think? This very perceptive medic noticed that the T-wave in V4 is far too tall for the QRS. Very abnormal. But computers are not programmed to find all abnormalities, including many that are dangerous. This is this one. How about ST Elevation? There is (as the computer measures -- at the side) more than 1 mm of STE in V2 and V3, but not the 1.5 mm that would trigger "STEMI" in a woman. Thus, you have to decide if this STE is due to normal variant or due to ischemia. Normal

2017 Dr Smith's ECG Blog

70. Can Computed Tomography?Assessed Right-Sided Ventricular Dysfunction Predict Mortality in Hemodynamically Stable Pulmonary Embolism?

Can Computed Tomography?Assessed Right-Sided Ventricular Dysfunction Predict Mortality in Hemodynamically Stable Pulmonary Embolism? Systematic Review Snapshot TAKE-HOME MESSAGE Right-sided ventricular dysfunction assessed by computed tomography (CT) isassociatedwithall-causeshort-termmortalityandmorestronglyassociatedwith mortality caused by pulmonary embolism. Can Computed Tomography–Assessed Right-Sided Ventricular Dysfunction Predict Mortality in Hemodynamically Stable Pulmonary Embolism (...) ? EBEM Commentators Jason R. West, MD Department of Emergency Medicine Albert Einstein College of Medicine Jacobi Medical Center Bronx, NY Benjamin W. Friedman, MD, MS Department of Emergency Medicine Albert Einstein College of Medicine Monte?ore Medical Center Bronx, NY Results The search identi?ed 289 articles. All but 46 were excluded accord- ing to the title and abstract. The remaining studies were subjected to a detailed review, and 10 studies were included in the re- view. Of these, 8 included

2015 Annals of Emergency Medicine Systematic Review Snapshots

71. Assessment of midpalatal suture ossification using cone-beam computed tomography (PubMed)

Assessment of midpalatal suture ossification using cone-beam computed tomography The degree of ossification of the midpalatal suture is an important factor in the selection of treatment procedure, especially in young individuals. Considering the discrepancies in the results of studies on the exact time of the closure of this suture, the present study was undertaken to evaluate ossification and morphology of the suture with the use of CBCT.In the present cross-sectional study, the CBCT images (...) of the maxilla in 144 Iranian subjects (72 males, 72 females) with an age range of 10 to 70 years, referring to a private radiology center in Sari, Iran, were evaluated. The CBCT images were evaluated in the axial cross-sectional slice at 1 mm intervals to determine morphology and the maturation stage of the suture and its degree of ossification. The six developmental stages that were observed were as follows: stage A, a direct line without disturbances; stage B, a scalloped appearance in the suture; stage C

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2017 Electronic physician

72. Frequency and volumetry of infraorbital ethmoid cells (Haller cells) on cone-beam computed tomograms (CBCT) of the mid-face (PubMed)

Frequency and volumetry of infraorbital ethmoid cells (Haller cells) on cone-beam computed tomograms (CBCT) of the mid-face Objective: The aim of this study was to determine the frequency and morphology of Haller cells using a new radiological technique that allows examination of the facial skull. Material and methods: In a single center retrospective cohort study the cone-beam computed tomography (CBCT) volume data of the maxillary sinus of 199 patients were analysed (398 paranasal sinuses (...) examination procedures with respect to the target object. Conclusions: Bony variants of paranasal sinuses can be analysed using CBCT as an alternative to computed tomography (CT), whereas OPG images do not reliably detect Haller cells.

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2017 GMS Interdisciplinary plastic and reconstructive surgery DGPW

73. Computed Tomography to Evaluate Children with Suspected Appendicitis

Computed Tomography to Evaluate Children with Suspected Appendicitis Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should be considered (...) study only. It may not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Computed Tomography to Evaluate Children

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

74. Merging Electronic Health Record Data and Genomics for Cardiovascular Research

of using the EHR for cardiovascular genetic research. Landmark genetic findings in cardiovascular research have come from both single-center studies and large consortia. In the majority of these studies, DNA from blood samples in a biorepository was linked to clinical information in either a paper medical record or a study record or file. We are moving to an era of EHR-coupled biobanks. An EHR-coupled biobank is a bank of biological specimens linked to data in the EHR. The biological samples can be DNA (...) such as a radiographic image or scanned text document, but these forms cannot easily be searched for content. The counterpart to EHR data is administrative data, which include data on healthcare delivery, insurance enrollment, and claims data for reimbursement. Administrative data are generally structured and often encompass a large number of patients, making them historically attractive as a source for analyses. The most widely used administrative data set is likely from the Centers for Medicare and Medicaid

2016 American Heart Association

75. Multidisciplinary Management of Leaks After One-Anastomosis Gastric Bypass in a Single-Center Series of 2780 Consecutive Patients. (PubMed)

Multidisciplinary Management of Leaks After One-Anastomosis Gastric Bypass in a Single-Center Series of 2780 Consecutive Patients. Few data exist in the literature concerning leaks after one-anastomosis gastric bypass (OAGB). Our aim was to describe the incidence, presentation, and management of leaks after OAGB.A private clinic in France.Between May 2010 and December 2017, 2780 consecutive patients underwent OAGB. A retrospective chart review was performed on the 46 patients (1.7%) who (...) experienced postoperative leaks.Leaks arose from the anastomosis in 6 cases (13%) and from the gastric pouch in 27 cases (59%), while the remaining 13 patients (28%) had leaks from an undetermined origin. Management followed a standardized algorithm taking into consideration the clinical situation and findings on an oral contrast computed tomography (CT) scan. All patients were treated by fasting, total parenteral nutrition, and antimicrobial therapy. Nine patients (20%) could be managed by medical

2019 Obesity Surgery

76. Safety and Early Oncologic Outcomes of Lung Resection in Patients with Isolated Pulmonary Recurrent Prostate Cancer: A Single-center Experience. (PubMed)

Safety and Early Oncologic Outcomes of Lung Resection in Patients with Isolated Pulmonary Recurrent Prostate Cancer: A Single-center Experience. The introduction of novel imaging approaches for recurrent prostate cancer (PC) has paved the way for the use of nonsystemic approaches in patients with recurrent disease. While use of surgery or radiotherapy is standard for men with nodal or bone recurrence only, there are no significant data on the possible curative role of surgery for pulmonary (...) metastases. We aimed to assess the efficacy of lung resection in patients with isolated pulmonary recurrence after radical prostatectomy (RP) for clinically localized PC. Overall, nine patients with biochemical recurrence after RP and either single (n=4) or multiple (n=5) pulmonary uptake spots on fluorodeoxyglugose, choline, or prostate-specific membrane antigen positron emission tomography/computed tomography underwent a total of 20 lung resections between 2011 and 2017 at our institution

2019 European Urology

77. Comparison of four models predicting the malignancy of pulmonary nodules: A single-center study of Korean adults. (PubMed)

Comparison of four models predicting the malignancy of pulmonary nodules: A single-center study of Korean adults. Four commonly used clinical models for predicting the probability of malignancy in pulmonary nodules were compared. While three of the models (Mayo Clinic, Veterans Association [VA], and Brock University) are based on clinical and computed tomography (CT) characteristics, one model (Herder) additionally includes the 18F-fluorodeoxyglucose (FDG) uptake value among the positron (...) emission tomography (PET) characteristics. This study aimed to compare the predictive power of these four models in the context of a population drawn from a single center in an endemic area for tuberculosis in Korea.A retrospective analysis of 242 pathologically confirmed nodules (4-30 mm in diameter) in 242 patients from January 2015 to December 2015 was performed. The area under the receiver operating characteristic curve (AUC) was used to assess the predictive performance with respect

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2018 PLoS ONE

78. Human Intelligence & Artificial Intelligence in Medicine: A day with the Stanford Presence Center

& Environmental Sciences Multi-disciplinary Sciences Medicine & Health Research Analysis & Scientific Policy Post navigation in Uncategorized post-i Last week, PLOS Medicine and PLOS ONE editors Linda Nevin and Meghan Byrne attended Human Intelligence & Artificial Intelligence (HIAI) in Medicine, a Stanford Presence Center symposium. HIAI brought together thought leaders in medicine, computer science and policy to envisage an inclusive, equitable and humane experience in medicine with AI solutions. A few (...) Presence Center was founded by Stanford’s Vice Chair for the Theory and Practice of Medicine, Abraham Verghese, a leader at Stanford in advocating for and teaching fully engaged physical exams. HIAI commenced the development of a shared agenda to steer AI toward its most beneficial implementation. Can AI be developed to augment the physician’s intelligence, rather than attempt to replace it? Luminaries from medicine, computer science and policy shared their concerns and aspirations. In the 1960s, Dr

2018 PLOS Blogs Network

79. A single-center, open-label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers. (PubMed)

A single-center, open-label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers. Brivaracetam (BRV) and levetiracetam (LEV) are antiepileptic drugs that bind synaptic vesicle glycoprotein 2A (SV2A). In vitro and in vivo animal studies suggest faster brain penetration and SV2A occupancy (SO) after dosing with BRV than LEV. We evaluated human brain penetration and SO time course of BRV and LEV (...)  mg) and 4 hours postdose of LEV (250-600 mg). Half-time of 11 C-UCB-J signal change was computed from displacement measurements. Half-saturation concentrations (IC50 ) were determined from calculated SO.Observed tracer displacement half-times were 18 ± 6 minutes for BRV (100 mg, n = 4), 9.7 and 10.1 minutes for BRV (200 mg, n = 2), and 28 ± 6 minutes for LEV (1500 mg, n = 6). Estimated corrected half-times were 8 minutes shorter. The SO was 66%-70% for 100 mg intravenous BRV, 84%-85% for 200 mg

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2019 Epilepsia

80. Microcomputed Assessment of Transportation, Centering Ratio, Canal Area, and Volume Increase after Single-file Rotary and Reciprocating Glide Path Instrumentation in Curved Root Canals: A Laboratory Study. (PubMed)

the root canal preparation, changes in the root canals regarding the volume, surface area, SMI, transportation made by the files, and the change of their centering ability in the apical, middle, and coronal third were analyzed by micro-CT imaging. The data were statistically evaluated using 1-way analysis of variance and the Kruskal-Wallis test with a significance level set at 5% (P < .05).The WOGG and RP file systems showed better centering abilities at all thirds compared with the PG file system (P (...) Microcomputed Assessment of Transportation, Centering Ratio, Canal Area, and Volume Increase after Single-file Rotary and Reciprocating Glide Path Instrumentation in Curved Root Canals: A Laboratory Study. The aim of this study was to compare the transportation and centering abilities of the ProGlider (PG; Dentsply-Sirona, Ballaigues, Switzerland), WaveOne Gold Glider (WOGG; Dentsply-Sirona), and R-Pilot (RP; VDW, Munich, Germany) file systems and the changes in the structure model index (SMI

2019 Journal of Endodontics

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