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21. Computer classes and games in virtual reality environment to reduce loneliness among students of an elderly reference center: Study protocol for a randomised cross-over design. (PubMed)

Computer classes and games in virtual reality environment to reduce loneliness among students of an elderly reference center: Study protocol for a randomised cross-over design. Physical and mental changes associated with aging commonly lead to a decrease in communication capacity, reducing social interactions and increasing loneliness. Computer classes for older adults make significant contributions to social and cognitive aspects of aging. Games in a virtual reality (VR) environment stimulate (...) , spontaneously enrolled in computer classes for beginners. Data collection will be done in 3 moments: moment 0 (T0) - at baseline; moment 1 (T1) - after 8 typical computer classes; and moment 2 (T2) - after 8 computer classes which include 15 minutes for practicing games in VR environment. A characterization questionnaire, the short version of the Short Social and Emotional Loneliness Scale for Adults (SELSA-S) and 3 games with VR (Random, MoviLetrando, and Reaction Time) will be used. For the intervention

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2017 Medicine

22. Root Canal Transportation and Centering Ability of Nickel-Titanium Rotary Instruments in Mandibular Premolars Assessed Using Cone-Beam Computed Tomography (PubMed)

Root Canal Transportation and Centering Ability of Nickel-Titanium Rotary Instruments in Mandibular Premolars Assessed Using Cone-Beam Computed Tomography The aim of this study was to evaluate, using cone-beam computed tomography (CBCT), transportation and centralization of different nickel-titanium (NiTi) rotary instruments.One hundred and twenty eight mandibular premolars were selected and instrumented using the following brands of NiTi files: WaveOne, WaveOne Gold, Reciproc, ProTaper Next (...) , ProTaper Gold, Mtwo, BioRaCe and RaCe. CBCT imaging was performed before and after root canal preparation to obtain measurements of mesial and distal dentin walls and calculations of root canal transportation and centralization. A normal distribution of data was confirmed by the Kolmogorov-Smirnov and Levene tests, and results were assessed using the Kruskal-Wallis test. Statistical significance was set at 5%.ProTaper Gold produced the lowest canal transportation values, and RaCe, the highest. ProTaper

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2017 The open dentistry journal

23. Diagnosing giant cell tumor of the bone using positron emission tomography/computed tomography: A retrospective study of 20 patients from a single center (PubMed)

Diagnosing giant cell tumor of the bone using positron emission tomography/computed tomography: A retrospective study of 20 patients from a single center The aim of the present study was to evaluate the sensitivity of positron emission tomography/computed tomography (PET/CT) in the diagnosis of giant cell tumor of the bone (GCTB) using the maximum standard uptake value (SUVmax), which indicates the metabolic rate of tissue. Patients diagnosed with pathologically confirmed GCTB between January (...) 2006 and July 2015 were included in the study. Data from PET/CT scans and pathological and clinical reports for all patients were retrospectively reviewed. The SUVmax value from the PET/CT scan of each patient was retrieved and analyzed. A total of 20 patients [12 male and 8 female; age range, 12-45 years; mean age ± standard deviation (SD), 33.5±15.7] with complete PET/CT data and a pathologically and clinically confirmed diagnosis were examined. The SUVmax of GCTB was between 1.8 and 18.6

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2017 Oncology letters

24. Relationship Between PROMIS Computer Adaptive Tests and Legacy Hip Measures Among Patients Presenting to a Tertiary Care Hip Preservation Center. (PubMed)

Relationship Between PROMIS Computer Adaptive Tests and Legacy Hip Measures Among Patients Presenting to a Tertiary Care Hip Preservation Center. Legacy hip outcome measures may be burdensome to patients and sometimes yield floor or ceiling effects. Patient-Reported Outcomes Measurement Information System (PROMIS) computer adaptive tests (CATs) allow for low-burden data capture and limited ceiling and floor effects.The purpose of this study was to determine whether the PROMIS CAT domains (...) demonstrate correlation against commonly used legacy patient-reported outcome measures in a population of patients presenting to a tertiary care hip preservation center. The authors hypothesized the following: (1) PROMIS CAT scores based on physical function (PF), pain interference (PIF), pain behavior, and pain intensity would show strong correlation with the following legacy scores: modified Harris Hip Score (mHHS), International Hip Outcome Tool-12 (iHOT-12), Hip Outcome Score (HOS) Sports

2019 American Journal of Sports Medicine

25. Addition of dihydrogen to a borylborenium center †Electronic supplementary information (ESI) available. CCDC 1543216 (4). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc04987k (PubMed)

Addition of dihydrogen to a borylborenium center †Electronic supplementary information (ESI) available. CCDC 1543216 (4). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc04987k The activation of a H-H bond, the simplest covalent bond, is a fundamentally important process. Addition of H2 to an elemental center typically occurs on low valent transition metal or main group complexes through oxidative addition to afford metal dihydride complexes (...) . In contrast, activation of H2 on a high valent center generally results in heterolytic cleavage of the H-H bond to a proton and hydride. Here, we report experimental and computational evidence for the addition of H2 to a borenium center in an N-heterocyclic carbene (NHC) coordinated borylborenium cation, which leads to the formation of a dihydroborenium complex accompanied by the elimination of two σ-bonded substituents, namely mesityl (Mes) and pinacolboryl (Bpin) groups, as mesitylboronic ester.

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2017 Chemical Science

26. Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K) (PubMed)

Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K) 29276451 2018 11 13 1536-1268 16 2 2017 Apr-Jun IEEE pervasive computing IEEE Pervasive Comput Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K). 18-22 10.1109/MPRV.2017.29 Kumar Santosh S is a professor and Moss Chair of Excellence in computer science at the University of Memphis and director of the MD2K Center of Excellence. Abowd Gregory G is a Regents' Professor and J.Z. Liang Chair in the School of Interactive (...) of California, San Diego. Marlin Benjamin M BM is an assistant professor at the University of Massachusetts, Amherst. Murphy Susan S is the H.E. Robbins Distinguished University Professor of Statistics, professor of psychiatry, and research professor at the Institute of Social Research at the University of Michigan. Rehg James M JM is a professor in the School of Interactive Computing at the Georgia Institute of Technology. He is deputy director of MD2K and leads MD2K's data science research. Nahum-Shani

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2017 IEEE pervasive computing

27. Improving patient safety and efficiency of medication reconciliation through the development and adoption of a computer-assisted tool with automated electronic integration of population-based community drug data: the RightRx project. (PubMed)

Improving patient safety and efficiency of medication reconciliation through the development and adoption of a computer-assisted tool with automated electronic integration of population-based community drug data: the RightRx project. Many countries require hospitals to implement medication reconciliation for accreditation, but the process is resource-intensive, thus adherence is poor. We report on the impact of prepopulating and aligning community and hospital drug lists with data from (...) population-based and hospital-based drug information systems to reduce workload and enhance adoption and use of an e-medication reconciliation application, RightRx.The prototype e-medical reconciliation web-based software was developed for a cluster-randomized trial at the McGill University Health Centre. User-centered design and agile development processes were used to develop features intended to enhance adoption, safety, and efficiency. RightRx was implemented in medical and surgical wards

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2017 Journal of the American Medical Informatics Association

28. Comparison of rigid and deformable registration through the respiratory phases of four-dimensional computed tomography image data sets for radiotherapy after breast-conserving surgery. (PubMed)

Comparison of rigid and deformable registration through the respiratory phases of four-dimensional computed tomography image data sets for radiotherapy after breast-conserving surgery. The aim of this study was to compare the geometric differences in gross tumor volume (GTV) and surgical clips propagated by rigid image registration (RIR) and deformable image registration (DIR) using a four-dimensional computed tomography (4DCT) image data set for patients treated with boost irradiation (...) or accelerated partial breast irradiation after breast-conserving surgery (BCS).The 4DCT data sets of 44 patients who had undergone BCS were acquired. GTV and selected clips were manually delineated on end-inhalation phase (CT0) and end-exhalation phase (CT50) images of 4DCT data sets. Subsequently, the GTV and selected clips from CT0 images were transformed and propagated to CT50 images using RIR and DIR, respectively. The geometric differences in GTV and surgical clips from DIR were compared with those

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2017 Medicine

29. Children and adolescents with cystic fibrosis display moderate bone microarchitecture abnormalities: data from high-resolution peripheral quantitative computed tomography. (PubMed)

Children and adolescents with cystic fibrosis display moderate bone microarchitecture abnormalities: data from high-resolution peripheral quantitative computed tomography. We investigated whether bone microstructure assessed by high-resolution peripheral quantitative tomography (HR-pQCT) could be altered in children and teenagers with cystic fibrosis (CF). In comparison to their healthy counterparts, bone microstructure was mildly affected at the tibial level only.Cystic fibrosis-related bone (...) disease (CFBD) may alter bone health, ultimately predisposing patients to bone fractures. Our aim was to assess bone microstructure using high-resolution peripheral quantitative tomography (HR-pQCT) in a cohort of children and teenagers with CF in comparison to age-, puberty-, and gender-matched healthy volunteers (HVs).In this single-center, prospective, cross-sectional study, we evaluated the HR-pQCT bone parameters of CF patients and compared them to those of the healthy volunteers.At a median age

2017 Osteoporosis International

30. Scalable Data Mining Algorithms in Computational Biology and Biomedicine (PubMed)

Gliwice, Poland. Ma Qin Q Department of Mathematics and Statistics and Department of Agronomy, Horticulture, and Plant Science, BioSNTR, South Dakota State University, Brookings, SD 57007, USA. Xu Yungang Y Center for Bioinformatics and Systems Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. eng Editorial 2017 02 28 United States Biomed Res Int 101600173 IM Algorithms Animals Biomedical Research Computational Biology Data Mining Humans 2016 12 29 2017 01 04 2017 3 25 6 0 2017 3 (...) Scalable Data Mining Algorithms in Computational Biology and Biomedicine 28337450 2018 10 02 2018 10 04 2314-6141 2017 2017 BioMed research international Biomed Res Int Scalable Data Mining Algorithms in Computational Biology and Biomedicine. 5652041 10.1155/2017/5652041 Zou Quan Q 0000-0001-6406-1142 School of Computer Science and Technology, Tianjin University, Tianjin 300354, China. Mrozek Dariusz D 0000-0001-6764-6656 Institute of Informatics, Silesian University of Technology, 44-100

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2017 BioMed research international

31. Computing patient data in the cloud: practical and legal considerations for genetics and genomics research in Europe and internationally (PubMed)

Computing patient data in the cloud: practical and legal considerations for genetics and genomics research in Europe and internationally Biomedical research is becoming increasingly large-scale and international. Cloud computing enables the comprehensive integration of genomic and clinical data, and the global sharing and collaborative processing of these data within a flexibly scalable infrastructure. Clouds offer novel research opportunities in genomics, as they facilitate cohort studies (...) to be carried out at unprecedented scale, and they enable computer processing with superior pace and throughput, allowing researchers to address questions that could not be addressed by studies using limited cohorts. A well-developed example of such research is the Pan-Cancer Analysis of Whole Genomes project, which involves the analysis of petabyte-scale genomic datasets from research centers in different locations or countries and different jurisdictions. Aside from the tremendous opportunities

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2017 Genome medicine

32. Strong Winds Ahead for Cloud Computing: Can Data Localization Threaten Future Growth?

Strong Winds Ahead for Cloud Computing: Can Data Localization Threaten Future Growth? Strong Winds Ahead for Cloud Computing: Can Data Localization Threaten Future Growth? | RAND Objective Analysis. Effective Solutions. Site-wide navigation Trending Topics Featured Research Activities Spotlight Commentary: Commentary: By Research Area Drawing upon decades of experience, RAND provides research services, systematic analysis, and innovative thinking to a global clientele that includes government (...) , the European Court of Justice ruled that the transfer of European Union consumer data to U.S. computer servers under the EU–U.S. Safe Harbor Agreement did not provide EU consumers with the equivalent protection they are entitled to under EU privacy laws. The overturning of Safe Harbor caused many to predict that the days of free and easy access to information between Europe and the United States had come to an end. Since then, a new agreement between the United States and the EU has been reached—but many

2016 The RAND blog

33. Computer modeling with randomized-controlled trial data informs the development of person-centered aged care homes. (PubMed)

Computer modeling with randomized-controlled trial data informs the development of person-centered aged care homes. To answer questions on the essential components (services, operations and resources) of a person-centered aged care home (iHome) using computer simulation.iHome was developed with AnyLogic software using extant study data obtained from 60 Australian aged care homes, 900+ clients and 700+ aged care staff. Bayesian analysis of simulated trial data will determine the influence (...) of different iHome characteristics on care service quality and client outcomes. Interim results: A person-centered aged care home (socio-cultural context) and care/lifestyle services (interactional environment) can produce positive outcomes for aged care clients (subjective experiences) in the simulated environment.Further testing will define essential characteristics of a person-centered care home.

2015 Neurodegenerative disease management

34. Can S100B Serum Biomarker Testing Reduce Head Computed Tomography Scanning in Children With Mild Traumatic Brain Injury?

Can S100B Serum Biomarker Testing Reduce Head Computed Tomography Scanning in Children With Mild Traumatic Brain Injury? Can S100B Serum Biomarker Testing Reduce Head Computed Tomography Scanning in Children With Mild Traumatic Brain Injury? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 73, Issue 5, Pages 456–458 Can S100B Serum Biomarker Testing Reduce Head Computed Tomography Scanning (...) in Children With Mild Traumatic Brain Injury? x Steven K. Roumpf , MD (EBEM Commentator) IU Health Academic Health Center, Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN x Julie L. Welch , MD (EBEM Commentator) Indiana Clinical and Translational Science Institute, Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN DOI: | Publication History Published online: November 20, 2018 Expand all Collapse all Article Outline Take-Home

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2019 Annals of Emergency Medicine Systematic Review Snapshots

35. 2017 AHA/ACC Key Data Elements and Definitions for Ambulatory Electronic Health Records in Pediatric and Congenital Cardiology: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards

disease share clinical nomenclature for disease classification and procedural coding. We use the term “EHR” as not only referring to the generic concept of such computer-based systems, but includes the idea that a patient’s medical information and discrete data capture may be stored in multiple systems, with clinical data standards enabling the appearance of a single repository. One of the greatest inefficiencies of the current approach to measuring clinical quality indicators and clinical (...) 2017 AHA/ACC Key Data Elements and Definitions for Ambulatory Electronic Health Records in Pediatric and Congenital Cardiology: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards 2017 AHA/ACC Key Data Elements and Definitions for Ambulatory Electronic Health Records in Pediatric and Congenital Cardiology: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards | Circulation

2017 American Heart Association

36. A 3-Month Randomized Controlled Pilot Trial of a Patient-Centered, Computer-Based Self-Monitoring System for the Care of Type 2 Diabetes Mellitus and Hypertension. (PubMed)

A 3-Month Randomized Controlled Pilot Trial of a Patient-Centered, Computer-Based Self-Monitoring System for the Care of Type 2 Diabetes Mellitus and Hypertension. This study was performed to evaluate the effects of a patient-centered, tablet computer-based self-monitoring system for chronic disease care. A 3-month randomized controlled pilot trial was conducted to compare the use of a computer-based self-monitoring system in disease self-care (intervention group; n = 33) with a conventional (...) , diastolic blood pressure, chronic disease knowledge, and frequency of self-monitoring. The data were collected at baseline and at 1-, 2-, and 3-month follow-up visits. The patients in the intervention group had a significant decrease in mean systolic blood pressure from baseline to 1 month (p < 0.001) and from baseline to 3 months (p = 0.043) compared with the control group. Significant improvements in the mean diastolic blood pressure were seen in the intervention group compared with the control group

2016 Journal of medical systems

37. Safety of Computed Tomographic Angiography in the Evaluation of Patients With Acute Stroke: A Single-Center Experience. (PubMed)

Safety of Computed Tomographic Angiography in the Evaluation of Patients With Acute Stroke: A Single-Center Experience. Noncontrasted head computed tomography (NCHCT) has long been the standard of care for acute stroke imaging. New guidelines recommending advanced vascular imaging to identify eligible patients for endovascular therapy have renewed safety concerns on the use of contrast in the emergent setting without laboratory confirmation of renal function.We compared computed tomographic (...) angiography (CTA) versus NCHCT alone during acute stroke evaluation with focus on renal safety and timeliness of therapy delivery. We reviewed data on all emergency department patients for whom the Acute Stroke Intervention Team was activated between December 2013 and September 2014. Primary outcomes included acute kidney injury and change in serum creatinine from presentation to 24 to 48 hours (Δ serum creatinine [Cr]). We assessed therapy delay using door-to-CT and door-to-needle times.Of 289 patients

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2016 Stroke

38. What Is the Utility of Coronary Computed Tomography Angiography Compared With Standard of Care for the Evaluation of Acute Chest Pain? (SRS diagnosis)

What Is the Utility of Coronary Computed Tomography Angiography Compared With Standard of Care for the Evaluation of Acute Chest Pain? (SRS diagnosis) TAKE-HOME MESSAGE Compared with existing standards of care for the evaluation of acute chest pain, coronary computed tomography (CT) angiography is associated with similar rates of major adverse events, but higher rates of revascularization. What Is the Utility of Coronary Computed Tomography Angiography Compared With Standard of Care (...) for the Evaluation of Acute Chest Pain? EBEM Commentators Michael Gottlieb, MD Chase Socha, MD Department of Emergency Medicine Rush University Medical Center Chicago, IL Results The search strategy identi?ed 648 articles, of which 10 trials (6,285 total participants) met the inclusion criteria. The studies were published between 2007 and 2016, and none were deter- mined to be at high risk of bias. Six studies were performed in the ED and 4 studies were per- formed in the inpatient setting. The mean age ranged

2018 Annals of Emergency Medicine Systematic Review Snapshots

39. ACR–ASNR–ASSR–SPR Practice Parameter for the Performance of Computed Tomography (CT) of the Spine

S. An analysis of cervical spine magnetic resonance imaging findings after normal computed tomographic imaging findings in pediatric trauma patients: ten-year experience of a level I pediatric trauma center. J Trauma Acute Care Surg. 2013;74(4):1102-1107. 39. Kadom N, Khademian Z, Vezina G, Shalaby-Rana E, Rice A, Hinds T. Usefulness of MRI detection of cervical spine and brain injuries in the evaluation of abusive head trauma. Pediatr Radiol. 2014;44(7):839- 848. 40. Mortazavi M, Gore PA, Chang (...) ACR–ASNR–ASSR–SPR Practice Parameter for the Performance of Computed Tomography (CT) of the Spine PRACTICE PARAMETER CT_Spine / 1 The American College of Radiology, with more than 30,000 members, is the principal organization of radiologists, radiation oncologists, and clinical medical physicists in the United States. The College is a nonprofit professional society whose primary purposes are to advance the science of radiology, improve radiologic services to the patient, study the socioeconomic

2019 American Society of Neuroradiology

40. ACR–ASNR–SPR Practice Parameter for the Performance of Computed Tomography (CT) Perfusion in Neuroradiologic Imaging Revised

. If needed, the head can be immobilized using forehead and chin straps. A contrast infusion pump should be connected to the cannula. The head is centered to the scanner isocenter. C. Examination Techniques There are 2 CT perfusion approaches using intravenously administered iodinated contrast that use different data acquisition and analysis methods. These methods differ in their volume coverage (ie, the amount of tissue that can be imaged during 1 data acquisition or 1 imaged series), the amount (...) on a dedicated computer display rather than from film or paper copy, as this permits interactive adjustment of brightness, contrast, and color scale. If maps of blood volume, blood flow, mean transit time, Tmax, and blood-brain barrier permeability are produced, they should be interpreted as a coherent set of data; none of the maps should be interpreted in isolation without knowledge of other types of images available for review and/or in the absence of the clinical context [4-6]. CT perfusion (CTP

2019 American Society of Neuroradiology

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