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181. Computers are the modern stethoscope

forward, there is a step backward. As a family doc, I spent the first 19 years of my practice in a care center, away from the main clinic. I didn’t have access to the same chart as the specialist. I hungered for the electronic record. But the day it arrived, it brought its own challenges. Remember back to 1990: We didn’t have sleek flat screens in the rooms, we had big bulky monitors. The exam rooms themselves weren’t built with a doc and a computer in mind. I found myself swirling on my stool to talk (...) to the patient. Of course, initially, nothing was in the computer to help me, and I found myself playing physician data entry person. Now I have an office designed with the EHR in mind. The screens can be turned so the patients can see. For an established patient, much background data is there. I have learned navigation tools and tricks, so there is less typing. But, what have I lost? Scroll back to 1964, age five. I followed my daddy on hospital rounds. Nothing made me happier than to hear people ask if I

2018 KevinMD blog

182. Residential Consumer-Centric Demand-Side Management Based on Energy Disaggregation-Piloting Constrained Swarm Intelligence: Towards Edge Computing (PubMed)

computing—a method of optimizing cloud computing technologies by driving computing capabilities at the IoT edge of the Internet as one of the emerging trends in engineering technology—addresses bandwidth-intensive contents and latency-sensitive applications required among sensors and central data centers through data analytics at or near the source of data. A non-intrusive load-monitoring technique proposed previously is utilized to automatic determination of physical characteristics (...) Residential Consumer-Centric Demand-Side Management Based on Energy Disaggregation-Piloting Constrained Swarm Intelligence: Towards Edge Computing The emergence of smart Internet of Things (IoT) devices has highly favored the realization of smart homes in a down-stream sector of a smart grid. The underlying objective of Demand Response (DR) schemes is to actively engage customers to modify their energy consumption on domestic appliances in response to pricing signals. Domestic appliance

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2018 Sensors (Basel, Switzerland)

183. Heart rate-reducing therapy with add-on ivabradine and bisoprolol before coronary computed tomographic angiography in a fast-track ambulatory setting (PubMed)

Heart rate-reducing therapy with add-on ivabradine and bisoprolol before coronary computed tomographic angiography in a fast-track ambulatory setting Objective This study was performed to determine whether add-on oral ivabradine in patients treated with beta blockers 1 hour before coronary computed tomographic angiography (CCTA) is effective in lowering the heart rate and thus improving CCTA quality. Methods In this single-center cohort study, the data of 294 patients referred for ambulant CCTA

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2018 The Journal of international medical research

184. Computational Approach to Musical Consonance and Dissonance (PubMed)

Computational Approach to Musical Consonance and Dissonance In sixth century BC, Pythagoras discovered the mathematical foundation of musical consonance and dissonance. When auditory frequencies in small-integer ratios are combined, the result is a harmonious perception. In contrast, most frequency combinations result in audible, off-centered by-products labeled "beating" or "roughness;" these are reported by most listeners to sound dissonant. In this paper, we consider second-order beats (...) , a kind of beating recognized as a product of neural processing, and demonstrate that the data-driven approach of Recurrence Quantification Analysis (RQA) allows for the reconstruction of the order in which interval ratios are ranked in music theory and harmony. We take advantage of computer-generated sounds containing all intervals over the span of an octave. To visualize second-order beats, we use a glissando from the unison to the octave. This procedure produces a profile of recurrence values

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2018 Frontiers in psychology

185. Tracking the NGS revolution: managing life science research on shared high-performance computing clusters (PubMed)

Tracking the NGS revolution: managing life science research on shared high-performance computing clusters Next-generation sequencing (NGS) has transformed the life sciences, and many research groups are newly dependent upon computer clusters to store and analyze large datasets. This creates challenges for e-infrastructures accustomed to hosting computationally mature research in other sciences. Using data gathered from our own clusters at UPPMAX computing center at Uppsala University, Sweden (...) are installed each month for NGS projects than for non-NGS projects. We developed usage and efficiency metrics and show that computing jobs for NGS projects use more RAM than non-NGS projects, are more variable in core usage, and rarely span multiple nodes. NGS jobs use booked resources less efficiently for a variety of reasons. Active monitoring can improve this somewhat.Hosting NGS projects imposes a large administrative burden at UPPMAX due to large numbers of inexperienced users and diverse and rapidly

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2018 GigaScience

186. Towards Portable Large-Scale Image Processing with High-Performance Computing (PubMed)

Towards Portable Large-Scale Image Processing with High-Performance Computing High-throughput, large-scale medical image computing demands tight integration of high-performance computing (HPC) infrastructure for data storage, job distribution, and image processing. The Vanderbilt University Institute for Imaging Science (VUIIS) Center for Computational Imaging (CCI) has constructed a large-scale image storage and processing infrastructure that is composed of (1) a large-scale image database (...) using the eXtensible Neuroimaging Archive Toolkit (XNAT), (2) a content-aware job scheduling platform using the Distributed Automation for XNAT pipeline automation tool (DAX), and (3) a wide variety of encapsulated image processing pipelines called "spiders." The VUIIS CCI medical image data storage and processing infrastructure have housed and processed nearly half-million medical image volumes with Vanderbilt Advanced Computing Center for Research and Education (ACCRE), which is the HPC facility

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2018 Journal of Digital Imaging

187. A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes (PubMed)

A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes To explore the genetic determinants of obesity and Type 2 diabetes (T2D), the German Center for Diabetes Research (DZD) conducted crossbreedings of the obese and diabetes-prone New Zealand Obese mouse strain with four different lean strains (B6, DBA, C3H, 129P2) that vary in their susceptibility to develop T2D. Genome-wide linkage analyses localized more than (...) 290 quantitative trait loci (QTL) for obesity, 190 QTL for diabetes-related traits and 100 QTL for plasma metabolites in the outcross populations. A computational framework was developed that allowed to refine critical regions and to nominate a small number of candidate genes by integrating reciprocal haplotype mapping and transcriptome data. The efficiency of the complex procedure was demonstrated for one obesity QTL. The genomic interval of 35 Mb with 502 annotated candidate genes was narrowed

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2018 Human molecular genetics

188. An Efficient Neural-Network-Based Microseismic Monitoring Platform for Hydraulic Fracture on an Edge Computing Architecture (PubMed)

into consideration, an edge-computing-based platform, namely Edge-to-Center LearnReduce, is presented in this work. The platform consists of a data center with many edge components. At the data center, a neural network model combined with convolutional neural network (CNN) and long short-term memory (LSTM) is designed and this model is trained by using previously obtained data. Once the model is fully trained, it is sent to edge components for events detection and data reduction. At each edge component (...) An Efficient Neural-Network-Based Microseismic Monitoring Platform for Hydraulic Fracture on an Edge Computing Architecture Microseismic monitoring is one of the most critical technologies for hydraulic fracturing in oil and gas production. To detect events in an accurate and efficient way, there are two major challenges. One challenge is how to achieve high accuracy due to a poor signal-to-noise ratio (SNR). The other one is concerned with real-time data transmission. Taking these challenges

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2018 Sensors (Basel, Switzerland)

189. Role of intellectual capital on creation of innovation capabilities in HIS and computer units (PubMed)

during 2015.The present study seeks to evaluate the impact of different aspects of intellectual property on innovations in computer and HIS units at selected medical centers in the city of Isfahan during 2015 (2015).Population of this research includes staff working in computer and HIS units of 10 medical centers. Data were collected using a questionnaire made by the researcher. A written questionnaire (also referred to as self-administered questionnaire) is a data collection tool in which written (...) the base of economy in today's world. In today's knowledge-based economy, production and exploitation of knowledge play the main roles in the process of wealth creation. Considering key contributions of knowledge management in competitiveness of organizations and their entry into global arenas, this study sought to evaluate the impact of different aspects of intellectual property on innovations in computer and health information system (HIS) units at selected medical center in the city of Isfahan

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2018 Journal of education and health promotion

190. Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain

: April 27, 2018 Last Update Posted: October 15, 2018 Last Verified: October 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Jae Seung Kim, Asan Medical Center: [18F]PI-2620, tauopathy, positron emission computed tomography Additional relevant MeSH terms: Layout table for MeSH terms Parkinson Disease Alzheimer (...) Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have

2018 Clinical Trials

191. Computed Tomography (CT) Guided Lung Biopsy With Plug

Computed Tomography (CT) Guided Lung Biopsy With Plug Computed Tomography (CT) Guided Lung Biopsy With Plug - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Computed Tomography (CT) Guided Lung Biopsy (...) by (Responsible Party): Haseem Ashraf, University Hospital, Akershus Study Details Study Description Go to Brief Summary: Protocol Title: Computed Tomography (CT) Guided Lung Biopsy with BioSentry Plug, Evaluation of Safety and Efficacy. Condition or disease Intervention/treatment Phase Computed Tomography, Biopsy, Pneumothorax, Chest Tube, Plug Device: The BioSentry Tract Sealant System Not Applicable Detailed Description: Protocol Summary: Prospective, randomized, controlled, unblinded, post-market, single

2018 Clinical Trials

192. Exploring the Mechanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and Computational Fluid Dynamics II (EMERALD II) Study

bypass graft surgery F. Patients with stents in two or more vessel territories prior to CCTA G. Patients with ACS culprit lesion in a stented vessel H. Patients with revascularization after CCTA and before ACS event Additional exclusion criteria for Computational Fluid Dynamics A. Reference vessel diameter < 2.5mm on CCTA B. Poor quality CCTA images unsuitable for CFD analysis C. No available unprocessed CCTA data Contacts and Locations Go to Information from the National Library of Medicine To learn (...) : Joo Myung Lee, MD, MPH, PhD Samsung Medical Center More Information Go to Additional Information: Layout table for additonal information Responsible Party: Bon-Kwon Koo, Professor, Seoul National University Hospital ClinicalTrials.gov Identifier: Other Study ID Numbers: NCT1869 First Posted: July 19, 2018 Last Update Posted: July 19, 2018 Last Verified: July 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Layout table for additional information Studies a U.S

2018 Clinical Trials

193. Comparison of Computer-Assisted Navigation and Conventional Instrumentation for Bilateral Total Knee Arthroplasty

, 2018 Last Update Posted : September 13, 2018 Sponsor: Chang Gung Memorial Hospital Information provided by (Responsible Party): Chang Gung Memorial Hospital Study Details Study Description Go to Brief Summary: To compare the functional outcomes of Computer-Assisted Navigation (CAS) and Conventional Instrumentation TKA at the 8-year follow-up. Condition or disease Intervention/treatment Arthropathy of Knee Joint Procedure: Computer-Assisted Navigation TKA Detailed Description: The data (...) , lateral radiographs of the knee and standing long-leg radiographs of the lower extremity were obtained pre- and postoperatively. The lower extremities were fully extended so that the tibial tuberosities were facing forward and the lateral malleoli were 15 cm apart to ensure that the tibia was vertical and facing forward with minimal rotation. The X-ray beam (20-25 mA/s; 80-85 kV) was centered at the knee joint level at a distance of 120-140 cm.Radiographic data included the mechanical axis angle

2018 Clinical Trials

194. Evaluation of Fractional Flow Reserve Calculated by Computed Tomography Coronary Angiography in Patients Undergoing TAVR

valve stenosis. Condition or disease Intervention/treatment Phase Aortic Valve Stenosis Coronary Artery Disease Device: iFR / FFR measurement Not Applicable Detailed Description: This is a single-center, open-label, exploratory, prospective study. Among patients who undergo coronary computed tomography angiography (cCTA) prior to TAVR, those with moderate or severe stenotic lesions will be included in the study. Patients from whom consent is obtained following TAVR will be enrolled in the study (...) : None (Open Label) Primary Purpose: Diagnostic Official Title: Evaluation of Fractional Flow Reserve Calculated by Computed Tomography Coronary Angiography in Patients Undergoing Transcatheter Aortic Valve Replacement(FORTUNA): Single Center, Open-label, Exploratory, Prospective Study Estimated Study Start Date : September 13, 2018 Estimated Primary Completion Date : March 31, 2022 Estimated Study Completion Date : March 31, 2022 Resource links provided by the National Library of Medicine related

2018 Clinical Trials

195. Computer-based Social Skills Training for Autism Spectrum Disorder

attention and gaze pattern data during dyadic interaction tasks. Auditory impairment (that cannot be corrected by a hearing aid) that would significantly impede the valid collection of test measures. Profound intellectual disability or sensory-motor difficulties that would preclude valid use of diagnostic instruments and/or use of a computer or mobile computing device. A DSM 5 disorder or other psychiatric symptoms that would interfere with the participant's ability to participate in the study (e.g (...) Computer-based Social Skills Training for Autism Spectrum Disorder Computer-based Social Skills Training for Autism Spectrum Disorder - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Computer-based Social

2018 Clinical Trials

196. Preparative Fasting Before Contrast-enhanced Computed Tomography

Center, Israel Information provided by (Responsible Party): Naiel Bisharat, HaEmek Medical Center, Israel Study Details Study Description Go to Brief Summary: The study aims to determine whether there is a need for preparative fasting prior to contrast-enhanced computed tomography (CT). Condition or disease X-ray Contrast Media Adverse Reaction Detailed Description: The use of fasting orders for imaging and other procedures is common, this seemingly benign practice can lead to real harms to patients (...) Preparative Fasting Before Contrast-enhanced Computed Tomography Preparative Fasting Before Contrast-enhanced Computed Tomography - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Preparative Fasting Before

2018 Clinical Trials

197. Biofeedback-enhanced Interactive Computer-play for Youth With Cerebral Palsy

Biofeedback-enhanced Interactive Computer-play for Youth With Cerebral Palsy Biofeedback-enhanced Interactive Computer-play for Youth With Cerebral Palsy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Biofeedback-enhanced Interactive Computer-play for Youth With Cerebral Palsy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03677193 Recruitment Status : Not yet recruiting First Posted : September 19, 2018 Last Update Posted

2018 Clinical Trials

198. Computed Tomography Angiography Prediction Score for Side Branch Occlusion

. The CT-PRECISION (Computed Tomography angiography PREdiCtIon score for SIde branch Occlusion in coronary bifurcation interventioN) registry was designed to evaluate the application of coronary computed tomography angiography (coronary CTA) for the prediction of SB occlusion during percutaneous revascularization of bifurcation lesions. The main purpose of this single-center study is to develop a noninvasive CTA-based prediction tool to determine the procedural outcome of PCI in bifurcation lesions (...) Computed Tomography Angiography Prediction Score for Side Branch Occlusion Computed Tomography Angiography Prediction Score for Side Branch Occlusion - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Computed

2018 Clinical Trials

199. Quality improvement of functional diagnostics in dentistry through computer-aided diagnosis: a randomized controlled trial. (PubMed)

) in this study investigated whether computer-aided diagnosis (CADx) of temporomandibular disorders (TMD) offers quality advantages over traditional diagnosis (TRAD).Thirty-nine 5th-year dental students (examiners) at a university in Hamburg, Germany, received joint training in the diagnosis of TMD by clinical functional analysis and manual structural analysis ('orthopedic tests'). This study is based on anonymized data from 10 patients who were consecutively recruited at a specialized TMJ treatment center (...) Quality improvement of functional diagnostics in dentistry through computer-aided diagnosis: a randomized controlled trial. Functional diagnostic examinations such as clinical functional analysis and manual structural analysis ('orthopedic tests') allow the dentist to establish a structured diagnosis. Previously, the process of correlating findings with the appropriate diagnoses was guided by human thought processes alone. The experimental diagnostic randomized controlled trial (RCT

2018 International journal of computerized dentistry

200. Computed tomographic appearance of abdominal lymph nodes in healthy cats (PubMed)

Computed tomographic appearance of abdominal lymph nodes in healthy cats Computed tomography (CT) is commonly used in veterinary medicine and plays an important role in disease identification and cancer staging. Identification of abnormal abdominal lymph nodes is important for clinical, therapeutic, and prognostic decision making. No published study describes the CT appearance of abdominal lymph nodes in healthy cats.All abdominal lymph centers will be identified on CT with the majority (...) , and pancreaticoduodenal lymph nodes identified in 16/16 cats. Lymph node size and shape varied among lymph centers with nearly all lymph nodes homogeneously contrast enhancing in 515/525. Significant negative correlations were identified between age and length (P = .0166) and width (P = .0387) of abdominal lymph nodes as well as age and number of sacral lymph nodes (P = .0493). Intranodal fat was present in 18/525 lymph nodes.CT readily permitted identification and characterization of feline abdominal lymph nodes

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2018 Journal of Veterinary Internal Medicine

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