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Clinical Dehydration Scale

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1. Diagnostic accuracy of three clinical dehydration scales: a systematic review. (PubMed)

Diagnostic accuracy of three clinical dehydration scales: a systematic review. To systematically assess the diagnostic accuracy of the Clinical Dehydration Scale (CDS), the WHO Scale and the Gorelick Scale in identifying dehydration in children with acute gastroenteritis (AGE).Three databases, two registers of clinical trials and the reference lists from identified articles were searched for diagnostic accuracy studies in children with AGE. The index tests were the CDS, WHO Scale and Gorelick (...) Scale, and reference standard was the percentage loss of body weight. The main analysed outcomes were the sensitivity, specificity, positive likelihood ratio (LR) and negative LR.Ten studies were included. In high-income countries, the CDS provided a moderate-to-large increase in the post-test probability of predicting moderate to severe (≥6%) dehydration (positive LR 3.9-11.79), but it was of limited value for ruling it out (negative LR 0.55-0.71). In low-income countries, the CDS showed limited

2017 Archives of Disease in Childhood

2. Clinical Dehydration Scale

Clinical Dehydration Scale Clinical Dehydration Scale Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Clinical Dehydration Scale (...) Clinical Dehydration Scale Aka: Clinical Dehydration Scale II. Indications Dehydration evaluation in children ages 1 to 36 months III. Criteria Appearance Score 0: Normal Score 1: Thirsty, restless or lethargic; irritable when touched Score 2: Drowsy to comatose, limp, cold, sweaty Eyes Score 0: Normal Score 1: Slightly sunken Score 2: Very sunken Mucous Membranes Score 0: Moist Score 1: Sticky Score 2: Dry Tears Score 0: Normal tears Score 1: Decreased tear Score 2: Absent tears IV. Interpretation

2019 FP Notebook

3. Comparison of clinical and biochemical markers of dehydration with the clinical dehydration scale in children: a case comparison trial. (PubMed)

Comparison of clinical and biochemical markers of dehydration with the clinical dehydration scale in children: a case comparison trial. The clinical dehydration scale (CDS) is a quick, easy-to-use tool with 4 clinical items and a score of 1-8 that serves to classify dehydration in children with gastroenteritis as no, some or moderate/severe dehydration. Studies validating the CDS (Friedman JN) with a comparison group remain elusive. We hypothesized that the CDS correlates with a wide spectrum (...) of established markers of dehydration, making it an appropriate and easy-to-use clinical tool.This study was designed as a prospective double-cohort trial in a single tertiary care center. Children with diarrhea and vomiting, who clinically required intravenous fluids for rehydration, were compared with minor trauma patients who required intravenous needling for conscious sedation. We compared the CDS with clinical and urinary markers (urinary electrolytes, proteins, ratios and fractional excretions

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2014 BMC Pediatrics

4. CRACKCast E173 – Infectious Diarrheal Disease and Dehydration

the components of the Gorelick scale In 2015, a meta-analysis found both the CDS and Gorelick scale improve diagnostic accuracy over unstructured physician assessment. However, with only approximately 80% accuracy, neither can definitively rule in or out dehydration in infants and children. There is the ten point or the four point (underlined) Gorelick scale… Refer to Table 172.10 in Rosen’s 9 th edition for the Clinical Dehydration Scale including the Gorelick scale. Gorelick scale: No or minimal (...) with infectious diarrhea is not recommended! Dehydration Assessment The degree of volume depletion is estimated from the history and physical examination findings. In severe dehydration, 20 mL/kg of 0.9% saline (or other appropriate isotonic crystalloid solution) given intravenously at a rapid rate should reverse signs of shock within 5 to 15 minutes. Repeated boluses of 20 mL/kg are indicated until clinical improvement occurs, but volume requirements greater than 60 mL/kg without signs of improvement suggest

2018 CandiEM

5. The diagnostic accuracy of Clinical Dehydration Scale in identifying dehydration in children with acute gastroenteritis: a systematic review. (PubMed)

The diagnostic accuracy of Clinical Dehydration Scale in identifying dehydration in children with acute gastroenteritis: a systematic review. To systematically update diagnostic accuracy of the Clinical Dehydration Scale (CDS) in clinical recognition of dehydration in children with acute gastroenteritis.Six databases were searched for diagnostic accuracy studies in which population were children aged 1 to 36 months with acute gastroenteritis; index test was the CDS; and reference test was post (...) -illness weight gain.Three studies involving 360 children were included. Limited evidence showed that in high-income countries the CDS provides strong diagnostic accuracy for ruling in moderate and severe (>6%) dehydration (positive likelihood ratio 5.2-6.6), but has limited value for ruling it out (negative likelihood ratio 0.4-0.55). In low-income countries, the CDS has limited value either for ruling moderate or severe dehydration in or out. In both settings, the CDS had limited value for ruling

2014 Clinical pediatrics

6. Drinking in the Evidence Around Mild-Moderate Dehydration Management in Kids with Gastroenteritis

). • RCT of 647 children, mean age 28 months with generally mild dehydration (82% scored =1 out of 8 on clinical dehydration scale). Randomized to half-strength apple juice or preferred fluid versus apple-flavored, sucralose-sweetened pediatric electrolyte maintenance solution, 5 mL administered every 2-5 minutes while in the emergency department. 2 o Those who vomited received oral ondansetron. o Composite outcome: Treatment failure (including return to care, hospitalization, and IV rehydration). ? 17 (...) care research. www.acfp.ca April 18, 2017 Drinking in the Evidence Around Mild-Moderate Dehydration Management in Kids with Gastroenteritis Clinical Question: What is the best management of mild-moderate dehydration in children with gastroenteritis? Bottom Line: For children with mild to moderate dehydration due to gastroenteritis, oral rehydration is equivalent to IV therapy. Half- strength apple juice is as good as electrolyte maintenance solution and appears to be superior in children =24 months

2017 Tools for Practice

7. Neurocognitive Disorders and Dehydration in Older Patients: Clinical Experience Supports the Hydromolecular Hypothesis of Dementia (PubMed)

Neurocognitive Disorders and Dehydration in Older Patients: Clinical Experience Supports the Hydromolecular Hypothesis of Dementia Abnormalities of water homeostasis can be early expressions of neuronal dysfunction, brain atrophy, chronic cerebrovasculopathy and neurodegenerative disease. The aim of this study was to analyze the serum osmolality of subjects with cognitive impairment. One thousand and ninety-one consecutive patients attending the Alzheimer’s Evaluation Unit were evaluated (...) with the Mini-Mental State Examination (MMSE), 21-Item Hamilton Depression Rating Scale (HDRS-21), Activities of Daily Living (ADL), Instrumental-ADL (IADL), Mini Nutritional Assessment (MNA), Exton-Smith Scale (ESS), and Cumulative Illness Rating Scale (CIRS). For each patient, the equation for serum osmolality developed by Khajuria and Krahn was applied. Five hundred and seventy-one patients had cognitive decline and/or depression mood (CD-DM) and 520 did not have CD-DM (control group). Patients with CD

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2018 Nutrients

8. Comparing the Diagnostic Accuracy of Clinical Dehydration Scales Among Small Children

Comparing the Diagnostic Accuracy of Clinical Dehydration Scales Among Small Children Comparing the Diagnostic Accuracy of Clinical Dehydration Scales Among Small Children - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Comparing the Diagnostic Accuracy of Clinical Dehydration Scales Among Small Children The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02249845 Recruitment Status : Unknown Verified January 2016 by Piotr Dziechciarz, MD, Medical University of Warsaw. Recruitment status was: Recruiting

2014 Clinical Trials

9. Randomized Controlled Trial of Micronized Dehydrated Human Amnion/Chorion Membrane (dHACM) Injection Compared to Placebo for the Treatment of Plantar Fasciitis

Randomized Controlled Trial of Micronized Dehydrated Human Amnion/Chorion Membrane (dHACM) Injection Compared to Placebo for the Treatment of Plantar Fasciitis Failure of conservative management to reduce/eliminate symptoms of plantar fasciitis (PF) may indicate need for advanced treatments. This study reports Level 1 evidence supporting 3-month safety and efficacy of micronized dehydrated human amnion/chorion membrane (dHACM) injection as a treatment for PF.A prospective, single-blind (...) , randomized controlled trial was conducted at 14 sites in the United States. Subjects were randomized to receive 1 injection, in the affected area, of micronized dHACM (n=73) or 0.9% sodium chloride placebo (n=72). Safety/efficacy assessments were conducted at 4 weeks, 8 weeks, 3 months, 6 months, and 12 months postinjection, using visual analog scale (VAS) for pain, Foot Function Index-Revised (FFI-R) score, and presence/absence of adverse events. Primary outcome was mean change in VAS score between

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2018 EvidenceUpdates

10. The prevalence of dehydration among older adults across settings: a systematic review and meta-analysis.

The prevalence of dehydration among older adults across settings: a systematic review and meta-analysis. Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files (...) tumor 4. No control group 5. Combination therapy or contamination 6. Not about analgesics used in the clinic Full text-screening: As above, with the addition of: 7. No relevant outcome measure reported ">Prioritise the exclusion criteria Example: Two reviewers will independently extract data from each article. We first try to extract numerical data from tables, text or figures. If these are not reported, we will extract data from graphs using digital ruler software. In case data are not reported

2019 PROSPERO

11. What risk is carried and what are the consequences of dehydration or renal impairment following defunctioning ileostomy in patients undergoing major resection for colorectal cancer?

); Renal histological damage as assessed by Jablonski scale; continuous; Jablonski score. ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data (...) What risk is carried and what are the consequences of dehydration or renal impairment following defunctioning ileostomy in patients undergoing major resection for colorectal cancer? Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility

2019 PROSPERO

12. Feasibility Study of a Nurse Intervention to Impact Mucositis Severity and Prevent Dehydration

or more studies before adding more. Feasibility Study of a Nurse Intervention to Impact Mucositis Severity and Prevent Dehydration The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03416582 Recruitment Status : Recruiting (...) for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 15 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Supportive Care Official Title: Feasibility Study of a Nurse-Delivered Telephone Intervention To Impact Mucostitis Symptom Severity and Prevent Dehydration in Lung and Head/Neck Cancer Patients Undergoing Chemoradiation: A Pilot Study Actual Study Start Date : November 29, 2018 Estimated Primary Completion Date

2018 Clinical Trials

13. Dehydration is how you define it: comparison of 318 blood and urine athlete spot checks (PubMed)

Dehydration is how you define it: comparison of 318 blood and urine athlete spot checks Clinical medicine defines dehydration using blood markers that confirm hypertonicity (serum sodium concentration ([Na+])>145 mmol/L) and intracellular dehydration. Sports medicine equates dehydration with a concentrated urine as defined by any urine osmolality (UOsm) ≥700 mOsmol/kgH2O or urine specific gravity (USG) ≥1.020.To compare blood versus urine indices of dehydration in a cohort of athletes (...) undergoing routine screenings.318 collegiate athletes (193 female) provided blood and urine samples and asked to rate how thirsty they were on a 10-point visual analogue scale. Serum was analysed for [Na+], while serum and UOsm were measured using an osmometer. USG was measured using a Chemstrip. Data were categorised into dehydrated versus hydrated groupings based on these UOsm and USG thresholds.Using UOsm ≥700 mOsmol/kgH2O to define dehydration, 55% of athletes were classified as dehydrated. Using any

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2018 BMJ Open Sport — Exercise Medicine

14. Use of Human Dehydrated Amnion Chorion Allograft in Closed Hemorroidectomy

: Interventional (Clinical Trial) Estimated Enrollment : 15 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: A Prospective Case Series for Closed Hemorrhoidectomy - Efficacy of External Hemorrhoid Repair Using a Dehydrated Human Amnion Chorion Membrane Actual Study Start Date : February 5, 2018 Estimated Primary Completion Date : September 30, 2018 Estimated Study Completion Date : September 30, 2018 Resource links provided (...) Use of Human Dehydrated Amnion Chorion Allograft in Closed Hemorroidectomy Use of Human Dehydrated Amnion Chorion Allograft in Closed Hemorroidectomy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Use

2018 Clinical Trials

15. Capillary Refill for Assessment of Dehydration

by (Responsible Party): Dr. David Sheridan, Oregon Health and Science University Study Details Study Description Go to Brief Summary: Capillary refill is used clinically to assess multiple things in children. This is a prospective observational study of the correlation between capillary refill time and degree of dehydration in children seen in a pediatric ED. Condition or disease Intervention/treatment Dehydration in Children Diagnostic Test: Capillary Refill Detailed Description: All patient presenting (...) to the pediatric ER at OHSU less than 10 years are eligible to be enrolled if being seen for a condition putting them at risk for dehydration including emesis, diarrhea, etc. Children will have their capillary refill time measured and then sent home with a digital scale to track their weight. This will serve as the standard for calculating percent dehydration. When a patient has reached a stable weight at 1 week we will assume this is their healthy weight. There is no intervention in the study. Study Design Go

2018 Clinical Trials

16. The Effects of Dehydration on the Performance of Judoka

also want to see if the results are different in a dehydrated versus euhydrated state. Condition or disease Intervention/treatment Phase Dehydration Other: Dehydration Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 27 participants Allocation: Randomized Intervention Model: Crossover Assignment Masking: None (Open Label) Primary Purpose: Other Official Title: The Effects of Dehydration on the Performance (...) The Effects of Dehydration on the Performance of Judoka The Effects of Dehydration on the Performance of Judoka - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Effects of Dehydration on the Performance

2018 Clinical Trials

17. Efficacy of Dehydrated Cell and Protein Concentrate Versus Corticosteroid

of Dehydrated Cell and Protein Concentrate Versus Corticosteroid The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03710005 Recruitment Status : Recruiting First Posted : October 17, 2018 Last Update Posted : November 9, 2018 See (...) (CSI) or a dehydrated cell and protein concentrate (dCPC) product, Ascent Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 140 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Official Title: Randomized Control Study Comparing Efficacy of a Dehydrated Cell and Protein Concentrate (dCPC) ("Ascent") Versus Corticosteroid Actual Study Start Date

2018 Clinical Trials

18. Pediatric Dehydration Assessment at Triage: Prospective Study on Refilling Time (PubMed)

. Reliability was assessed by comparing the triage nurse's measurements with those obtained by the physician. Validity was demonstrated by using 6 parameters suggestive of dehydration. Comparison between refilling time (RT) and a validated Clinical Dehydration Score (CDS) was also considered. The scale's discriminative ability was evaluated for the outcome of starting intravenous rehydration therapy by using a receiver operating characteristic (ROC) curve.Participants were 242 children. All nurses found (...) Pediatric Dehydration Assessment at Triage: Prospective Study on Refilling Time Dehydration is a paediatric medical emergency but there is no single standard parameter to evaluate it at the emergency department. Our aim was to evaluate the reliability and validity of capillary refilling time as a triage parameter to assess dehydration in children.This was a prospective pilot cohort study of children who presented to two paediatric emergency departments in Italy, with symptoms of dehydration

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2018 Pediatric gastroenterology, hepatology & nutrition

19. Randomized Controlled Trial of Micronized Dehydrated Human Amnion/Chorion Membrane (dHACM) Injection Compared to Placebo for the Treatment of Plantar Fasciitis. (PubMed)

Randomized Controlled Trial of Micronized Dehydrated Human Amnion/Chorion Membrane (dHACM) Injection Compared to Placebo for the Treatment of Plantar Fasciitis. Failure of conservative management to reduce/eliminate symptoms of plantar fasciitis (PF) may indicate need for advanced treatments. This study reports Level 1 evidence supporting 3-month safety and efficacy of micronized dehydrated human amnion/chorion membrane (dHACM) injection as a treatment for PF.A prospective, single-blind (...) , randomized controlled trial was conducted at 14 sites in the United States. Subjects were randomized to receive 1 injection, in the affected area, of micronized dHACM (n=73) or 0.9% sodium chloride placebo (n=72). Safety/efficacy assessments were conducted at 4 weeks, 8 weeks, 3 months, 6 months, and 12 months postinjection, using visual analog scale (VAS) for pain, Foot Function Index-Revised (FFI-R) score, and presence/absence of adverse events. Primary outcome was mean change in VAS score between

2018 Foot & Ankle International

20. Randomized Controlled Trial of Micronized Dehydrated Human Amnion/Chorion Membrane (dHACM) Injection Compared to Placebo for the Treatment of Plantar Fasciitis. (PubMed)

Randomized Controlled Trial of Micronized Dehydrated Human Amnion/Chorion Membrane (dHACM) Injection Compared to Placebo for the Treatment of Plantar Fasciitis. Failure of conservative management to reduce/eliminate symptoms of plantar fasciitis (PF) may indicate need for advanced treatments. This study reports Level 1 evidence supporting 3-month safety and efficacy of micronized dehydrated human amnion/chorion membrane (dHACM) injection as a treatment for PF.A prospective, single-blind (...) , randomized controlled trial was conducted at 14 sites in the United States. Subjects were randomized to receive 1 injection, in the affected area, of micronized dHACM (n=73) or 0.9% sodium chloride placebo (n=72). Safety/efficacy assessments were conducted at 4 weeks, 8 weeks, 3 months, 6 months, and 12 months postinjection, using visual analog scale (VAS) for pain, Foot Function Index-Revised (FFI-R) score, and presence/absence of adverse events. Primary outcome was mean change in VAS score between

2018 Foot & Ankle International

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