How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,184 results for

Clindamycin Topical

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

41. Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections

Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01697826 Recruitment Status : Completed First Posted : October

2012 Clinical Trials

42. Clindamycin Topical

Clindamycin Topical Clindamycin Topical Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Clindamycin Topical Clindamycin Topical Aka (...) : Clindamycin Topical , Cleocin-T , Benzaclin , Veltin , Ziana From Related Chapters II. Indication III. Preparations Gel, Lotion, Solution or foam 1% with gel (Benzaclin): 1%/5% or 1.2%/2.5% with gel (Veltin, Ziana) 1.2%/0.025% IV. Directions Apply a thin film qd/bid Often Used with a ( ) V. Advantages Only solution that reliably penetrates comedones Reaches bactericidal levels within comedones VI. Disadvantages Resistance develops in 25% of patients within 6 months Use in combination with (e.g. Benzaclin

2015 FP Notebook

43. Eradication of methicillin-resistant Staphylococcus aureus (MRSA) throat carriage: a randomised trial comparing topical treatment with rifampicin-based systemic therapy. (PubMed)

. A combination of rifampicin and either clindamycin or SXT was more effective in eliminating pharyngeal MRSA carriage compared with topical treatment with mupirocin only.Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved. (...) Eradication of methicillin-resistant Staphylococcus aureus (MRSA) throat carriage: a randomised trial comparing topical treatment with rifampicin-based systemic therapy. Eradication of methicillin-resistant Staphylococcus aureus (MRSA) colonisation may prevent transmission of strains between patients and reduces the risk of clinical infection. Colonisation of the throat is associated with prolonged carriage and is more difficult to eradicate. An open randomised study was conducted to evaluate

2018 International journal of antimicrobial agents

44. Open-Label, Randomized Study Evaluating the Absorption and Systemic Pharmacokinetics of Topically Applied IDP-126 Gel in Comparison With Control Gel

and plasma PK of topically applied IDP-126 Gel compared to Control Gel. Condition or disease Intervention/treatment Phase Acne Vulgaris Drug: IDP-126 Gel Drug: Control Gel Phase 1 Detailed Description: To evaluate the safety and plasma pharmacokinetics (PK) of clindamycin and adapalene in IDP-126 Gel compared with that from Control Gel in subjects with moderate to severe acne vulgaris (acne) during once daily topical application of IDP-126 Gel for 28 days. Study Design Go to Layout table for study (...) Open-Label, Randomized Study Evaluating the Absorption and Systemic Pharmacokinetics of Topically Applied IDP-126 Gel in Comparison With Control Gel Open-Label, Randomized Study Evaluating the Absorption and Systemic Pharmacokinetics of Topically Applied IDP-126 Gel in Comparison With Control Gel - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved

2018 Clinical Trials

45. Efficacy of topical combination of benzoyl peroxide 5% and clindamycin 1% for the treatment of progressive macular hypomelanosis: a randomized, doubleblind, placebo-controlled trial. (PubMed)

Efficacy of topical combination of benzoyl peroxide 5% and clindamycin 1% for the treatment of progressive macular hypomelanosis: a randomized, doubleblind, placebo-controlled trial. Progressive macular hypomelanosis is a dermatosis without definite etiology. There is no consensus or first-line therapy in the treatment of progressive macular hypomelanosis, and the treatment options used are very little effective.To evaluate the therapeutic efficacy of the topical combination of benzoyl peroxide (...) 5% and clindamycin 1% associated with sun exposure for the treatment of progressive macular hypomelanosis.This is a randomized, double-blind, placebo-controlled study in which patients were divided into two groups. Group A used the topical combination of benzoyl peroxide 5% and clindamycin 1% and Group B used gel cream as a placebo. Patients were advised to expose themselves to the sun on a daily basis and were systematically evaluated and photographed. The collected data were entered

2011 Anais brasileiros de dermatologia

46. Topical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and nicotinamide 4% in the treatment of acne: a multicentre-randomized trial. (PubMed)

Topical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and nicotinamide 4% in the treatment of acne: a multicentre-randomized trial. It has been shown that topical linoleic acid rich-phosphatidylcholine seems to be effective in normalization of follicular hyperkeratinization, whereas nicotinamide has an interesting anti-inflammatory effect. However, little is known about their combined effect on acne. A multicentre, double-blind, 12-week randomized vehicle and parallel-active control (...) study was conducted by clinical and biophysical non-invasive measurements to evaluate the efficacy, tolerability and safety of a 4% nicotinamide-phospholipidic (N-PHCL) emulsion vs. 1% topical clindamycin phosphate applied once daily. Four percentage N-PHCL cosmetic treatment resulted slightly superior to topical clindamycin with all the parameters studied for its better compliance and the global clinical improvement.© 2011 The Authors. ICS © 2011 Society of Cosmetic Scientists and the Société

2011 International journal of cosmetic science

47. Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. (Full text)

Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. Topical therapy with comedolytics and antibiotics are often advocated for mild and moderate severity acne vulgaris. Nadifloxacin, a new fluoroquinolone with anti-Propionibacterium acnes activity and additional anti-inflammatory activity, is approved for use in acne. This randomized controlled assessor blind trial compared the clinical (...) effectiveness and safety of eight weeks therapy of nadifloxacin 1% versus clindamycin 1% as add-on therapy to benzoyl peroxide (2.5%) in mild to moderate grade acne.The efficacy parameters were changes in the total, inflammatory and non-inflammatory lesion counts, Investigator Global Assessment (IGA), and Cardiff Acne Disability Index (CADI) scales from baseline to study end (eight weeks). All treatment emergent dermatological adverse events were evaluated for safety assessment.Out of 84 randomized subjects

2011 Indian journal of pharmacology PubMed

48. Use of Topical Phenytoin in Bisphosphonate-related Osteonecrosis of the Mandible

, infection and pain were in 1,6 and 12 months after treatment. Condition or disease Intervention/treatment Phase Osteonecrosis Due to Drugs, Jaw Drug: Topical Phenytoin 5% Not Applicable Detailed Description: All patients undergo surgical necrotic bone debridement in combination with antibiotic therapy (clindamycin 300 mg q8h) for 4 weeks . Patients who had BRON of the mandible randomly allocated in 2 groups. Group 1 underwent debridement of necrotic bone and the involved area closed primary and in group (...) Use of Topical Phenytoin in Bisphosphonate-related Osteonecrosis of the Mandible Use of Topical Phenytoin in Bisphosphonate-related Osteonecrosis of the Mandible - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding

2017 Clinical Trials

49. Topical Treatment and Prevalence of P. Acnes

Details Study Description Go to Brief Summary: This study is about preventing surgical site infections of the shoulder. We hope to learn if clindamycin alone, benzoyl peroxide alone, or clindamycin and benzoyl peroxide together can affect growth of Propionibacterium acnes in the dermal layer. Condition or disease Intervention/treatment Phase Surgical Site Infection Drug: Clindamycin 1% Gel Drug: Benzoyl peroxide 5% gel Drug: BenzaClin 5%-1% Topical Gel Phase 2 Detailed Description: P. acnes are skin (...) in the dermal layer. 12 volunteers who are normal volunteers, students, or employees of USC will each receive 4 punch biopsies from their back above the scapular spine, with each biopsy taken from a region of the skin treated with a different topical (topical clindamycin alone, topical benzoyl peroxide alone, topical clindamycin and benzoyl peroxide together, and a control). A 3df overall test of the treatment indicators will test for any differences in positivity for P Acnes among the treatments; pairwise

2017 Clinical Trials

50. Adjunctive Clindamycin for Cellulitis: Clinical Trial Comparing Flucloxacillin With or Without Clindamycin for the Treatment of Limb Cellulitis (C4C Trial).

Title: A Double Blind Randomised Control Trial to Measure the Effect of the Addition of Clindamycin to Flucloxacillin for the Treatment of Limb Cellulitis Study Start Date : October 2013 Actual Primary Completion Date : December 2015 Estimated Study Completion Date : January 2016 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Placebo Comparator: Flucloxacillin and placebo Intravenous or oral (...) Adjunctive Clindamycin for Cellulitis: Clinical Trial Comparing Flucloxacillin With or Without Clindamycin for the Treatment of Limb Cellulitis (C4C Trial). Adjunctive Clindamycin for Cellulitis: C4C Trial. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2013 Clinical Trials

51. A Study Comparing Clindamycin and Benzoyl Peroxide Gel 1.2%/3.75% to Onextonâ„¢ Gel in the Treatment of Acne Vulgaris

provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Clindamycin and BPO Gel 1.2%/3.75% Clindamycin and Benzoyl Peroxide Gel 1.2%/3.75% applied to the face once daily for 84 days. Drug: Clindamycin and Benzoyl Peroxide Gel 1.2%/3.75% Clindamycin and Benzoyl Peroxide Gel 1.2%/3.75% (Taro Pharmaceuticals Inc.) Other Name: Clindamycin, BPO Active Comparator: Onexton™ Gel Onexton™ Gel (Clindamycin and Benzoyl (...) A Study Comparing Clindamycin and Benzoyl Peroxide Gel 1.2%/3.75% to Onextonâ„¢ Gel in the Treatment of Acne Vulgaris A Study Comparing Clindamycin and Benzoyl Peroxide Gel 1.2%/3.75% to Onexton™ Gel in the Treatment of Acne Vulgaris - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2015 Clinical Trials

52. Clindamycin-rifampin Drug Interaction in the Treatment of Bone and Joint Infections

-induction (Cytochrome P450 3A4/3A5) on Plasma Clindamycin Concentrations, With Clindamycin Given Intravenously and Orally to Treat Bone-and-joint Infections Actual Study Start Date : December 2015 Estimated Primary Completion Date : December 2019 Estimated Study Completion Date : December 2019 Resource links provided by the National Library of Medicine related topics: available for: Groups and Cohorts Go to Intervention Details: Drug: usual antibiotic treatment pharmacological studies in patients (...) Clindamycin-rifampin Drug Interaction in the Treatment of Bone and Joint Infections Clindamycin-rifampin Drug Interaction in the Treatment of Bone and Joint Infections - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2015 Clinical Trials

53. Compound Adapalene and Clindamycin Hydrochloride Gel in Treatment of Patients With Acne

Study Start Date : March 2015 Estimated Primary Completion Date : December 2015 Estimated Study Completion Date : March 2016 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Treat group 1 Group 1: 0.1% Adapalene + 1% Clindamycin Hydrochloride Drug: Adapalene + Clindamycin Hydrochloride 0.1% Adapalene + 1% Clindamycin Hydrochloride Experimental: Treatment group 2 Group 2: 0.1% Adapalene + 2 (...) Compound Adapalene and Clindamycin Hydrochloride Gel in Treatment of Patients With Acne Compound Adapalene and Clindamycin Hydrochloride Gel in Treatment of Patients With Acne - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2015 Clinical Trials

54. Double-blind Placebo-controlled Trial of Generic Clindamycin/Benzoyl Peroxide Gel Versus Onexton Gel in Acne Vulgaris

of a Generic Clindamycin 1.2% and Benzoyl Peroxide 3.75% Gel to Onexton® Gel in Subjects With Acne Vulgaris Study Start Date : May 2015 Actual Primary Completion Date : October 2015 Actual Study Completion Date : November 2015 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Onexton gel Clindamycin 1.2% and benzoyl peroxide 3.75% topical gel Applied a thin film of medication onto 6 areas (...) of the face (chin, left cheek, right cheek, nose, left forehead, and right forehead) once daily Drug: Onexton Topical gel for treating acne Other Name: Clindamycin/benzoyl peroxide gel Experimental: Clindamycin/benzoyl peroxide gel Generic clindamycin 1.2% and benzoyl peroxide 3.75% topical gel. Applied a thin film of medication onto 6 areas of the face (chin, left cheek, right cheek, nose, left forehead, and right forehead) once daily Drug: Clindamycin/benzoyl peroxide gel Generic Clindamycin/benzoyl

2015 Clinical Trials

55. Efficacy and Tolerability of a Fixed Combination of Clindamycin Phosphate (1.2%) and Benzoyl Peroxide (3.75%) Aqueous Gel in Moderate and Severe Acne Vulgaris Subpopulations. (PubMed)

(55.1%) had at least a 2-grade reduction in evaluator's global severity score by week 12, and 30.6% of patients assessed their acne as 'clear' or 'almost clear'. Clindamycin-BP 3.75% was well tolerated, with no substantive differences from vehicle; and no patient discontinued due to AEs.Clindamycin-BP 3.75% aqueous gel is an effective and well-tolerated once-daily topical treatment for both moderate and severe acne. (...) Efficacy and Tolerability of a Fixed Combination of Clindamycin Phosphate (1.2%) and Benzoyl Peroxide (3.75%) Aqueous Gel in Moderate and Severe Acne Vulgaris Subpopulations. To evaluate the efficacy, safety, and tolerability of a fixed combination clindamycin phosphate 1.2% and benzoyl peroxide 3.75% (clindamycin-BP 3.75%) aqueous gel in the treatment of moderate and severe acne.Multicenter, double-blind study in 498 patients with moderate or severe acne randomized to clindamycin-BP 3.75

2015 Journal of drugs in dermatology : JDD

56. Clindamycin Phosphate 1.2%/Tretinoin 0.025% Gel for the Treatment of Acne Vulgaris: Which Patients are Most Likely to Benefit the Most? (PubMed)

Clindamycin Phosphate 1.2%/Tretinoin 0.025% Gel for the Treatment of Acne Vulgaris: Which Patients are Most Likely to Benefit the Most? Clindamycin phosphate 1.2%/tretinoin 0.025% gel is a topical combination formulation used once daily for the treatment of acne vulgaris, with approval in the United States for patients >12 years of age. Three 12-week, randomized, vehicle-controlled, pivotal trials included > 1,800 actively treated subjects. In addition, an open-label, 52-week study was also (...) completed with 442 subjects enrolled. The skin tolerability, safety, and efficacy of clindamycin phosphate 1.2%/tretinoin 0.025% gel applied once daily is well-established based on data from pivotal studies and analyses in other subsequent publications including from pooled analysis of results from 4,550 subjects. This article discusses results from the pivotal 12-week, Phase 3 studies of clindamycin phosphate 1.2%/tretinoin 0.025% gel applied once daily in 845 subjects with mild, moderate, or severe

2015 The Journal of clinical and aesthetic dermatology

57. Efficacy and safety of clindamycin-tretinoin gel versus clindamycin or tretinoin alone in acne vulgaris: a randomized, double-blind, vehicle-controlled study. (PubMed)

Efficacy and safety of clindamycin-tretinoin gel versus clindamycin or tretinoin alone in acne vulgaris: a randomized, double-blind, vehicle-controlled study. Topical combination therapy containing a retinoid and an antimicrobial is an effective treatment for acne vulgaris.To evaluate the efficacy and safety of a new topical formulation containing clindamycin phosphate 1.2% and tretinoin 0.025% solubilized in an aqueous-based gel (CT gel).1,649 participants were randomized 2:2:2:1 to 12 weeks (...) of double-blind treatment with CT gel, clindamycin, tretinoin, or vehicle gel administered once daily.Significantly more participants achieved 2-grade or greater improvement on the Investigator's Static Global Assessment score with CT gel versus clindamycin, tretinoin, or vehicle gel. CT gel produced a significantly greater reduction in absolute number of total lesions versus all other treatment groups, in total and noninflammatory lesions versus clindamycin, and in total and inflammatory lesions versus

2012 Journal of drugs in dermatology : JDD

58. BPX-01 Minocycline Topical Gel in the Treatment of Acne Vulgaris

of acne vulgaris including benzoyl peroxide, topical anti-inflammatory medications, corticosteroids, salicylic acid, α-hydroxy/glycolic, antibacterial/antiseptic soap or wash within 14 days prior to baseline (Day 0). Have used prescription topical retinoid (e.g. tretinoin, tazarotene, adapalene) or antimicrobials (e.g. clindamycin, erythromycin) or other prescription topical medications for the treatment of acne vulgaris within 28 days of baseline (Day 0). Have used systemic antibiotics or other (...) BPX-01 Minocycline Topical Gel in the Treatment of Acne Vulgaris BPX-01 Minocycline Topical Gel in the Treatment of Acne Vulgaris - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. BPX-01 Minocycline Topical

2016 Clinical Trials

59. Pilot Study of Tolerability and Effectivity of Two Combination Topical Acne Products

provided by (Responsible Party): GWT-TUD GmbH Study Details Study Description Go to Brief Summary: Study to compare two gels that are used to treat acne vulgaris. It will be compared the tolerability and effectivity following application of two combination topical acne products clindamycin 1% and 0.025% tretinoin gel (Acnatac® Gel), adapalen 0,1% and benzoyl peroxide 2,5% gel (Epiduo® Gel). Condition or disease Intervention/treatment Phase Acne Vulgaris Drug: Acnatac® Gel left face Drug: Epiduo® Gel (...) . Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 22 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Investigator) Primary Purpose: Treatment Official Title: Pilot Study of Tolerability and Effectivity Following Application of Two Combination Topical Acne Products Clindamycin 1% and 0.025% Tretinoin Gel (Acnatac® Gel), Adapalen 0,1% and Benzoyl Peroxide 2,5% Gel (Epiduo® Gel) Study Start

2016 Clinical Trials

60. Two Randomized, Double-Blind, Split-Face Studies to Compare the Irritation Potential of Two Topical Acne Fixed Combinations Over a 21-Day Treatment Period. (PubMed)

Two Randomized, Double-Blind, Split-Face Studies to Compare the Irritation Potential of Two Topical Acne Fixed Combinations Over a 21-Day Treatment Period. Topical therapy of acne vulgaris (acne) is very common, however cutaneous tolerability can influence patient adherence, and concerns about skin irritation have lead to a number of comparative split-face studies. Advances in formulation technology have provided new fixed combinations with lower concentrations of potentially irritating (...) ingredients without compromising efficacy. These developments now afford the opportunity to formulate fixed combinations with higher concentrations of active ingredients that may provide the greater efficacy needed in more severe disease with good tolerability.
Here, we compare the tolerability of two such developments, clindamycin-BP 3.75% gel and adapalene 0.3%-BP 2.5% gel, in healthy volunteers with no apparent facial redness or dryness over 21-days, using a split-face methodology.

2016 Journal of drugs in dermatology : JDD

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>