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Cleft Lip

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161. Letter to editor PRS regarding "Effect of One-Stage versus Two-Stage Palatoplasty on Hypernasality and Fistula Formation in Children with Complete Unilateral Cleft Lip and Palate: A randomised controlled trial." (PubMed)

Letter to editor PRS regarding "Effect of One-Stage versus Two-Stage Palatoplasty on Hypernasality and Fistula Formation in Children with Complete Unilateral Cleft Lip and Palate: A randomised controlled trial." 30601312 2019 02 28 1529-4242 143 3 2019 Mar Plastic and reconstructive surgery Plast. Reconstr. Surg. Effect of One-Stage versus Two-Stage Palatoplasty on Hypernasality and Fistula Formation in Children with Complete Unilateral Cleft Lip and Palate: A Randomized Controlled Trial. 668e (...) -669e 10.1097/PRS.0000000000005346 Parnis Juanita J Plastic Surgery, Trent Regional Cleft Network, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom. Syme-Grant Jonathan J eng Journal Article United States Plast Reconstr Surg 1306050 0032-1052 2019 1 3 6 0 2019 1 3 6 0 2019 1 3 6 0 ppublish 30601312 10.1097/PRS.0000000000005346

2018 Plastic and reconstructive surgery Controlled trial quality: uncertain

162. The Effects of Maxillary Expansion on Late Alveolar Bone Grafting in Patients With Unilateral Cleft Lip and Palate. (PubMed)

The Effects of Maxillary Expansion on Late Alveolar Bone Grafting in Patients With Unilateral Cleft Lip and Palate. The purpose of this study was to answer the research question of whether maxillary expansion provides enough postgraft stimulation to decrease the volume loss of alveolar bone grafts in patients with cleft lip and palate (CLP) who missed the appropriate treatment time.This study was designed as a prospective controlled clinical trial. Thirty patients in the permanent-dentition

2018 Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons Controlled trial quality: uncertain

163. Effect of Presurgical Nasoalveolar Molding on Nasal Symmetry in Unilateral Complete Cleft Lip/Palate Patients after Primary Cheiloplasty without Concomitant Nasal Cartilage Dissection: Early Childhood Evaluation. (PubMed)

Effect of Presurgical Nasoalveolar Molding on Nasal Symmetry in Unilateral Complete Cleft Lip/Palate Patients after Primary Cheiloplasty without Concomitant Nasal Cartilage Dissection: Early Childhood Evaluation. The objective of this study was to assess the efficacy of presurgical nasoalveolar molding (PNAM) on long-term nasal symmetry and shaping after primary cheiloplasty in patients with unilateral complete cleft lip/palate (UCL/P).This was a two-group, parallel, retrospective, randomized

2018 The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association Controlled trial quality: uncertain

164. Unilateral Cleft Lip and Palate Surgical Protocols and Facial Growth Outcomes. (PubMed)

Unilateral Cleft Lip and Palate Surgical Protocols and Facial Growth Outcomes. Adequate dentofacial growth is an objective of unilateral cleft lip and palate treatment. No study exists, comparing the dental arch of 5-year-old relationship after 2 treatment protocols: one with single-stage palatoplasty and another with delayed hard palate closure (DHPC). The authors hypothesized that the DHPC protocol provides better dentofacial growth.A single-center, single-surgeon Randomized Clinical Trial

2018 The Journal of craniofacial surgery Controlled trial quality: uncertain

165. The Effects of Age, Information, and Personal Contact on Attitudes Toward Individuals With Cleft-Lip and Palate. (PubMed)

The Effects of Age, Information, and Personal Contact on Attitudes Toward Individuals With Cleft-Lip and Palate. The aim of the study was to examine how information and brief personal contact with individuals who have a cleft lip and/or palate (CLP) affected attitudes and to compare these effects across two age cohorts.A pretest-posttest design was utilized to determine if accurate information and personal contact with an individual with CLP would affect cognitive, emotional, and behavioral (...) attitudes in participants without CLP. To assess attitudes, 189 participants without cleft lip and palate completed a modified version of the Multidimensional Attitudes Scale toward Persons with Disabilities ( Findler et al., 2007 ). The study included a child cohort (n = 78; Mean age = 10.01 years) and a young adult cohort (n = 111; Mean age = 19.58 years).Using a mixed MANCOVA, it was found that children's cognitive attitudes were significantly improved (22.54%) by information and personal contact

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2018 The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association Controlled trial quality: uncertain

166. Unilateral cleft lip repair: a comparison of treatment outcome with two surgical techniques using quantitative (anthropometry) assessment (PubMed)

Unilateral cleft lip repair: a comparison of treatment outcome with two surgical techniques using quantitative (anthropometry) assessment The unilateral cleft lip (UCL) repair technique has evolved extensively over the past century into its modern form and has been identified as an important determinant of treatment outcome. The aim of this study was to evaluate and compare treatment outcomes following repair of UCL using either the Tennison-Randall (triangular) technique or the Millard (...) rotation-advancement technique.This was a prospective randomized controlled study conducted at the Lagos University Teaching Hospital between January 2013 and July 2014. A total of 48 subjects with UCL presenting for primary surgery and who satisfied the inclusion criteria were recruited for the study. The subjects were randomly allocated into two surgical groups through balloting. Group A underwent cleft repair with the Tennison-Randall technique, while group B underwent cleft repair with the Millard

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2018 Journal of the Korean Association of Oral and Maxillofacial Surgeons Controlled trial quality: uncertain

167. A Comparative Evaluation of Efficacy and Efficiency of Grayson's Presurgical Nasoalveolar Molding Technique in Patients with Complete Unilateral Cleft Lip and Palate with Those Treated with Figueroa's Modified Technique (PubMed)

A Comparative Evaluation of Efficacy and Efficiency of Grayson's Presurgical Nasoalveolar Molding Technique in Patients with Complete Unilateral Cleft Lip and Palate with Those Treated with Figueroa's Modified Technique Presurgical nasoalveolar molding (PNAM) has been used for aligning and not only for approximating the maxillary alveolar segments preoperatively but also for improving the nasal symmetry and therefore facilitates primary surgical repairs in cleft patients.This study (...) was conducted to compare the efficacy and efficiency of Grayson's technique with Figueroa's modified presurgical nasoalveolar technique in complete unilateral cleft lip and palate (UCLP) infants.Twenty-two infants aged 10-15 days were randomly divided into two equal groups: Group I treated with Grayson's PNAM technique and Group II with Figueroa's PNAM technique.When we compared nasal asymmetry values preoperatively and postoperatively of Group I and Group II, it was found that the nostril height increased

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2018 Contemporary clinical dentistry Controlled trial quality: uncertain

168. A comparative study of immediate wound healing complications following cleft lip repair using either absorbable or non-absorbable skin sutures (PubMed)

A comparative study of immediate wound healing complications following cleft lip repair using either absorbable or non-absorbable skin sutures The aim of the study was to compare wound healing complications following the use of either absorbable or non-absorbable sutures for skin closure in cleft lip repair.This was a randomized controlled trial conducted at the Department of Oral and Maxillofacial Surgery, Lagos University Teaching Hospital, Idi Araba, Lagos State, Nigeria. Sixty subjects who (...) required either primary or secondary cleft lip repair and satisfied all the inclusion criteria were recruited and randomized into two groups (Vicryl group or Nylon group). The surgical wounds in all subjects were examined on 3rd, 7th, and 14th postoperative days (POD) for presence or absence of tissue reactivity, wound dehiscence, and local wound infection.Hemorrhage, tissue reactivity, wound dehiscence, and local wound infection were identified as wound healing complications following cleft lip repair

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2018 Journal of the Korean Association of Oral and Maxillofacial Surgeons Controlled trial quality: uncertain

169. Bilateral suprazygomatic maxillary nerve blocks vs. infraorbital and palatine nerve blocks in cleft lip and palate repair: A double-blind prospective, randomised study. (PubMed)

Bilateral suprazygomatic maxillary nerve blocks vs. infraorbital and palatine nerve blocks in cleft lip and palate repair: A double-blind prospective, randomised study. Cleft defects are common craniofacial malformations which require early surgical repair. These patients are at high risk of postoperative airway obstruction and respiratory failure. Cleft surgery may require high doses of opioids which may contribute to these complications.To compare the effectiveness of proximal and distal (...) approaches to blocking the maxillary nerve in patients undergoing cleft lip or cleft palate surgery.Randomised, controlled and double-blind study.The current study was carried out in Guwahati (Assam, India) between April 2014 and June 2014.A total of 114 patients older than 6 months who underwent cleft lip or cleft palate surgery were included. Exclusion criteria included coagulation disorders, peripheral neuropathy or chronic pain syndrome, infection in the puncture site, allergy to local anaesthetics

2018 European Journal of Anaesthesiology Controlled trial quality: predicted high

170. Effect of One-Stage versus Two-Stage Palatoplasty on Hypernasality and Fistula Formation in Children with Complete Unilateral Cleft Lip and Palate: A Randomized Controlled Trial. (PubMed)

Effect of One-Stage versus Two-Stage Palatoplasty on Hypernasality and Fistula Formation in Children with Complete Unilateral Cleft Lip and Palate: A Randomized Controlled Trial. Is one-stage or two-stage palatoplasty more effective for preventing fistula formation and hypernasality in patients with complete unilateral cleft lip and palate?This parallel blocked randomized controlled trial included 100 patients with nonsyndromic complete unilateral cleft lip and palate with a repaired cleft lip

2018 Plastic and reconstructive surgery Controlled trial quality: uncertain

171. Electromyographic Analysis of Masticatory Muscles in Cleft Lip and Palate Children with Pain-Related Temporomandibular Disorders (PubMed)

Electromyographic Analysis of Masticatory Muscles in Cleft Lip and Palate Children with Pain-Related Temporomandibular Disorders The aim of this study was to assess the electrical activity of temporalis and masseter muscles in children with cleft lip and palate (CLP) and pain-related temporomandibular disorders (TMD-P).The sample consisted of 31 CLP patients with a TMD-P (mean age 9.5 ± 1.8 years) and 32 CLP subjects with no TMD (mean age 9.2 ± 1.7 years). The children were assessed

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2018 Pain research & management

172. Pre-Surgical Infant Orthopedics (PSIO) And Naso-Alveolar Molding (NAM) Show Promise For Obtaining Normal Anatomy Of The Nose And Lip In Patients With Cleft Lip And Palate

Pre-Surgical Infant Orthopedics (PSIO) And Naso-Alveolar Molding (NAM) Show Promise For Obtaining Normal Anatomy Of The Nose And Lip In Patients With Cleft Lip And Palate UTCAT2163, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Pre-Surgical Infant Orthopedics (PSIO) And Naso-Alveolar Molding (NAM) Show Promise For Obtaining Normal Anatomy Of The Nose And Lip In Patients With Cleft Lip And Palate Clinical Question (...) In a child with cleft lip and palate, is there long-term benefit to pre-surgical naso-alveolar molding versus traditional surgical treatment alone? Clinical Bottom Line Long-term anthropologic studies comparing NAM to traditional treatment show equivocal results; however, pre-surgical infant orthopedics (PSIO) is gaining a body of literature to support it’s use. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1

2011 UTHSCSA Dental School CAT Library

173. Patients With Cleft Lip, Alveolus And Palate May Be Predisposed To Periodontal Disease, Especially In Teeth Adjacent To The Cleft

Patients With Cleft Lip, Alveolus And Palate May Be Predisposed To Periodontal Disease, Especially In Teeth Adjacent To The Cleft UTCAT2160, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Patients With Cleft Lip, Alveolus And Palate May Be Predisposed To Periodontal Disease, Especially In Teeth Adjacent To The Cleft Clinical Question Do patients with repaired cleft lip, alveolus, and palate have increased risk (...) of periodontal disease compared to normal subjects? Clinical Bottom Line While studies suggest that patient with cleft lip, palate and alveolus are predisposed to periodontal disease, especially in teeth near the cleft, further studies are required given lack of definitive evidence. Oral hygiene was also found to be poor in a majority of patients with cleft lip, alveolus, or palate, emphasizing the importance of good oral hygiene and close followup with these patients. Best Evidence (you may view more info

2011 UTHSCSA Dental School CAT Library

174. Rescue of lip switch flap at risk of necrosis due to venous congestion for cleft lip deformity (PubMed)

Rescue of lip switch flap at risk of necrosis due to venous congestion for cleft lip deformity In a 21-year-old male with bilateral cleft lip who developed marked venous congestion of a lip switch flap, we returned the grafted flap to the donor site to improve blood circulation of the flap and then re-transplanted it, which prevented flap necrosis. Here, we report the procedure and case.

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2016 Case Reports in Plastic Surgery & Hand Surgery

175. Vermilion Only Cross-lip Flap for Treating Whistle Deformity in Secondary Bilateral Cleft Lip Repair (PubMed)

Vermilion Only Cross-lip Flap for Treating Whistle Deformity in Secondary Bilateral Cleft Lip Repair Bilateral cleft lip repairs can result in various secondary deformities. One more commonly seen deformity, the whistle deformity, is characterized by a reduced or absent tubercle, orbicularis muscle diastasis, and abnormalities of the philtrum with notched appearance of cupid's bow. Various techniques have been described to address these problems. One common procedure is the lip-switch flap (...) originally described by Abbe in 1898, which has been modified by various surgeons. In these procedures, lower lip vermilion, mucosa, orbicularis, and lip skin are transposed to the upper lip on a pedicle that is later divided. In all these variations of the lip-switch procedure, the transposed tissue involves the entire lower lip skin-leaving large, unsightly, and unnecessary scars. It also brings abnormal tissue into the philtrum further distorting the upper lip. A modified cross-lip flap

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2016 Plastic and Reconstructive Surgery Global Open

176. Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data (PubMed)

Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data Previous research suggests a genetic overlap between nonsyndromic cleft lip with or without cleft palate (NSCL/P) and cancer. The aim of the present study was to identify common genetic risk loci for NSCL/P and cancer entities that have been reported to co-occur with orofacial clefting. This was achieved through the investigation of large genome

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2016 Genomics data

177. Cleft sidedness and congenitally missing teeth in patients with cleft lip and palate patients (PubMed)

Cleft sidedness and congenitally missing teeth in patients with cleft lip and palate patients The aim of this study was to investigate the prevalence of cleft sidedness, and the number of congenitally missing teeth in regard to cleft type and gender.The charts, models, radiographs, and intraoral photographs of 201 cleft patients including 131 males with the mean age of 12.3 ± 4 years and 70 females with the mean age of 12.6 ± 3.9 years were used for the study. T test, Chi-square, and binomial (...) tests were used for assessment of the data.One hundred forty-eight of the subjects suffered from cleft lip and palate followed by 41 subjects who suffered from cleft lip and alveolus. Chi-square test did not show any significant difference between the genders. Binomial test showed that left-sided cleft was more predominant in unilateral cleft lip and palate patients (P < 0.001). This study also showed that the upper lateral incisors were the most commonly missing teeth in the cleft area.

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2016 Progress in orthodontics

178. Genetic polymorphism of nonsyndromic cleft lip with or without cleft palate is associated with developmental dyslexia in Chinese school-aged populations (PubMed)

Genetic polymorphism of nonsyndromic cleft lip with or without cleft palate is associated with developmental dyslexia in Chinese school-aged populations Developmental dyslexia (DD) is a neurodevelopment disorder characterized by reading disabilities without apparent etiologies. Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a structural craniofacial malformation featured by isolated orofacial abnormalities. Despite substantial phenotypic differences, potential linkage between

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2016 Journal of Human Genetics

179. A discriminant analysis prediction model of non-syndromic cleft lip with or without cleft palate based on risk factors. (PubMed)

A discriminant analysis prediction model of non-syndromic cleft lip with or without cleft palate based on risk factors. A risk prediction model of non-syndromic cleft lip with or without cleft palate (NSCL/P) was established by a discriminant analysis to predict the individual risk of NSCL/P in pregnant women.A hospital-based case-control study was conducted with 113 cases of NSCL/P and 226 controls without NSCL/P. The cases and the controls were obtained from 52 birth defects' surveillance

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2016 BMC Pregnancy and Childbirth

180. Barriers to Reconstructive Surgery in Low- and Middle-Income Countries: A Cross-Sectional Study of 453 Cleft Lip and Cleft Palate Patients in Vietnam. (PubMed)

Barriers to Reconstructive Surgery in Low- and Middle-Income Countries: A Cross-Sectional Study of 453 Cleft Lip and Cleft Palate Patients in Vietnam. Despite health system advances, residents of low- and middle-income countries continue to experience substantial barriers in accessing health care, particularly for specialized care such as plastic and reconstructive surgery.A cross-sectional household survey of patients seeking surgical care for cleft lip and/or cleft palate was completed (...) addressed. Patients rely on charitable care outside the centralized health care system; as a result, surgical treatment of cleft lip and palate is delayed beyond the standard optimal window compared with more developed countries. Using these data, the authors developed a more evidence-based framework designed to understand health behaviors and perceptions regarding reconstructive surgical care.

2016 Plastic and reconstructive surgery

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