How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

2,883 results for

Cleft Lip

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

81. Establishing Content Validity of the CLEFT-Q: A New Patient-reported Outcome Instrument for Cleft Lip/Palate (PubMed)

Establishing Content Validity of the CLEFT-Q: A New Patient-reported Outcome Instrument for Cleft Lip/Palate The CLEFT-Q is a new patient-reported outcome instrument designed to measure outcomes that matter to patients. The aim of this qualitative study was to establish content validity of the CLEFT-Q in patients who differ by age and culture.Patients aged between 6 and 29 years were recruited from plastic surgery clinics in Canada, India, Ireland, the Philippines, the Netherlands (...) and the United States. Healthcare providers and other experts participated in a focus group or provided individual feedback. Input was sought on all aspects of the CLEFT-Q (item wording, instructions, and response options), and to identify missing content. Patient interviews and expert feedback took place between September 2013 and September 2014.Sixty-nine patients and 44 experts participated. The first draft of the CLEFT-Q consisted of 163 items measuring 12 constructs. The first round of feedback

Full Text available with Trip Pro

2017 Plastic and Reconstructive Surgery Global Open

82. Development and Evaluation of a Blog about Cleft Lip and Cleft Palate and Hearing (PubMed)

Development and Evaluation of a Blog about Cleft Lip and Cleft Palate and Hearing Introduction  Cleft lip and cleft palate can result in impairments in communication, specifically in hearing, making the use of technological resources such as blogs a fundamental guideline for health professionals. Objective  The aim of this study was to prepare and analyze the access to a blog about cleft lip and cleft palate and hearing as a pedagogical tool for health professionals. Methods  The first stage (...) of the scales, navigation and structure presented the lowest scores. Conclusion  The blog was developed and enabled greater access to information available on the web about cleft lip and cleft palate and hearing.

Full Text available with Trip Pro

2017 International archives of otorhinolaryngology

83. Centre‐level variation of treatment and outcome in 5‐year‐old children with non‐syndromic unilateral cleft lip and palate: The Cleft Care UK study. Part 1: Methodology and results for dento‐facial outcomes (PubMed)

Centre‐level variation of treatment and outcome in 5‐year‐old children with non‐syndromic unilateral cleft lip and palate: The Cleft Care UK study. Part 1: Methodology and results for dento‐facial outcomes Outline methods used to describe centre-level variation in treatment and outcome in children in the Cleft Care UK (CCUK) study. Report centre-level variation in dento-facial outcomes.Two hundred and sixty-eight five-year-old British children with non-syndromic unilateral cleft lip

Full Text available with Trip Pro

2017 Orthodontics & craniofacial research

84. Centre‐level variation in behaviour and the predictors of behaviour in 5‐year‐old children with non‐syndromic unilateral cleft lip: The Cleft Care UK study. Part 5 (PubMed)

Centre‐level variation in behaviour and the predictors of behaviour in 5‐year‐old children with non‐syndromic unilateral cleft lip: The Cleft Care UK study. Part 5 The aims of this study were to describe child behavioural and psychosocial outcomes associated with appearance and speech in the Cleft Care UK (CCUK) study. We also wanted to explore centre-level variation in child outcomes and investigate individual predictors of such outcomes.Two hundred and sixty-eight five-year-old (...) children with non-syndromic unilateral cleft lip and palate (UCLP) recruited to CCUK.Parents completed the Strengths and Difficulties questionnaire (SDQ) and reported their own perceptions of the child's self-confidence. Child facial appearance and symmetry were assessed using photographs, and intelligibility of speech was derived from audio-visual speech recordings. Centre-level variation in behavioural and psychosocial outcomes was examined using hierarchical models, and associations with clinical

Full Text available with Trip Pro

2017 Orthodontics & craniofacial research

85. Maternal Risk Factors Associated with the Development of Cleft Lip and Cleft Palate in Mexico: A Case-Control Study (PubMed)

Maternal Risk Factors Associated with the Development of Cleft Lip and Cleft Palate in Mexico: A Case-Control Study Cleft lip and palate, the most common developmental deformity, is seen worldwide and the etiology involves a combination of genetic and environmental factors. The purpose of this study was to determine the maternal risk factors associated with the development of cleft lip and cleft palate.We conducted a case control study at the Women's Hospital in Culiacan, Mexico. Medical (...) records were analyzed, including patients who delivered babies with and without cleft lip and cleft palate from January 2010 to December 2015. Multiple variables were analyzed, including gestational age, weight at birth, the use of folic acid and multivitamins during pregnancy, smoking, alcohol abuse, the use of recreational drugs, history of sexually transmitted infections, marital status, socioeconomic status, education, and nutritional status.We found that the maternal risk factors

Full Text available with Trip Pro

2017 Iranian journal of otorhinolaryngology

86. Assessment of differentially expressed plasma microRNAs in nonsyndromic cleft palate and nonsyndromic cleft lip with cleft palate (PubMed)

Assessment of differentially expressed plasma microRNAs in nonsyndromic cleft palate and nonsyndromic cleft lip with cleft palate Plasma microRNAs (miRNAs) have recently emerged as a new class of regulatory molecules that influence many biological functions. However, the expression profile of plasma microRNAs in nonsyndromic cleft palate (NSCP) or nonsyndromic cleft lip with cleft palate (NSCLP) remains poorly investigated. In this study, we used Agilent human miRNA microarray chips to monitor

Full Text available with Trip Pro

2016 Oncotarget

87. Association of TFAP2A gene polymorphism with susceptibility to non-syndromic cleft lip with or without palate risk in south Indian population (PubMed)

Association of TFAP2A gene polymorphism with susceptibility to non-syndromic cleft lip with or without palate risk in south Indian population The aetiology of non-syndromic cleft lip with or without cleft palate (NSCL/P) is complex involving multiple interacting genes and environmental factors. The primary objective of the present study was to investigate the role of TFAP2A gene single nucleotide polymorphisms (SNPs) in the pathogenesis of NSCL/P. In this study, 173 unrelated NSCL/P patients (...) and 176 controls without clefts were genotyped with TFAP2A rs1675414 (Exon 1), rs3798691 (Intron 1), and rs303050 (Intron 4) variants by allele-specific amplification using the KASPar SNP genotyping system. The method of multifactor dimensionality reduction (MDR) was used to analyze gene-gene interactions. TFAP2A polymorphisms are not found to be associated with non-syndromic cleft lip with or without cleft palate (NSCL/P) at either the genotype or allele levels. No linkage disequilibrium (LD

Full Text available with Trip Pro

2016 Meta gene

88. No Significant Difference in Velopharyngeal Function Between Conventional Orthognathic Surgery and Maxillary distraction for advancement of the maxilla in cleft lip and palate patients.

No Significant Difference in Velopharyngeal Function Between Conventional Orthognathic Surgery and Maxillary distraction for advancement of the maxilla in cleft lip and palate patients. UTCAT2625, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title No Significant Difference in Velopharyngeal Function Between Conventional Orthognathic Surgery and Maxillary Distraction for Advancement of the Maxilla in Cleft Lip and Palate (...) Patients Clinical Question Is there a difference in the development of velopharyngeal insufficiency when maxillary advancement in the cleft patient is performed with conventional orthognathic surgery or distraction osteogenesis? Clinical Bottom Line For repaired cleft lip and palate patients, there is no significant difference in development of velopharyngeal insufficiency after maxillary advancement due to conventional orthognathic (CO) surgery or distraction osteogenesis (DO). This is supported

2014 UTHSCSA Dental School CAT Library

89. Cleft lip and palate: maxillary distraction osteogenesis or orthognathic surgery for hypoplastic maxilla?

Cleft lip and palate: maxillary distraction osteogenesis or orthognathic surgery for hypoplastic maxilla? Cleft lip and palate: maxillary distraction osteogenesis or orthognathic surgery for hypoplastic maxilla? - National Elf Service Search National Elf Service Search National Elf Service » » » » Cleft lip and palate: maxillary distraction osteogenesis or orthognathic surgery for hypoplastic maxilla? Sep 14 2018 Posted by Cleft lip and palate (CLP) is a common birth defect. The prevalence (...) for the treatment of hypoplastic maxilla in people with cleft lip and palate. Methods Searches were conducted in the Cochrane Oral Health’s Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, LILACS BIREME Virtual Health Library (Latin American and Caribbean Health Science Information database), the US National Institutes of Health Trials Registry (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform

2018 The Dental Elf

90. Multi-modal Characterization of the Mature Septal Deformity and Airspace Associated with Unilateral Cleft Lip and Palate. (PubMed)

Multi-modal Characterization of the Mature Septal Deformity and Airspace Associated with Unilateral Cleft Lip and Palate. The nasal deformity that accompanies cleft conditions is often acknowledged as the most difficult obstacle to restoring facial balance in affected children. Despite considerable progress in the treatment of cleft lip and palate, the outcomes of cleft septorhinoplasty have proven variable and difficult to predict, possibly because of incomplete understanding of the underlying (...) anatomical deformities. The authors sought to characterize unilateral cleft septal and dorsal deformities through a detailed morphologic model based on photogrammetric, qualitative, and quantitative computerized tomographic image analysis.Twenty-five consecutive patients with a unilateral cleft nasal deformity without prior septorhinoplasty were included.Dorsal angulation, as measured by the nasal dorsal angle, consistently deviated away from the cleft side at a mean angle of 8.9 degrees. In a majority

2018 Plastic and reconstructive surgery

91. Philtrum reconstruction in unilateral cleft lip repair. (PubMed)

Philtrum reconstruction in unilateral cleft lip repair. The philtrum is an important aesthetic structure in the midface. A number of philtrum reconstruction techniques have been advocated for secondary cleft lip revision procedures. Conventional surgical management involves end-to-end orbicularis oris muscle approximation during primary cleft lip repair, often resulting in a flat lip appearance that requires secondary revision surgery at a later stage. A novel modification of the approximation (...) of the orbicularis oris muscle is described that may be implemented with any cleft lip technique in order to create an accentuated philtrum column for a natural looking philtrum. The muscle roll technique results in eversion of the orbicularis oris muscle, successfully recapturing the philtrum column topography. This is achieved by utilizing two inverted horizontal sutures, with an additional philtrum takedown suture placed in the region of the dimple to accentuate the philtrum anatomy and three-dimensional

2018 International Journal of Oral and Maxillofacial Surgery

92. Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology (PubMed)

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology There is increasing evidence that genetic risk variants for non-syndromic cleft lip/palate (nsCL/P) are also associated with normal-range variation in facial morphology. However, previous analyses are mostly limited to candidate SNPs and findings have not been consistently replicated. Here, we used polygenic risk scores (PRS) to test for genetic overlap between nsCL/P and seven biologically relevant facial

Full Text available with Trip Pro

2018 PLoS genetics

93. Nonsyndromic cleft lip and/or palate: A multicenter study of the dental anomalies involved (PubMed)

Nonsyndromic cleft lip and/or palate: A multicenter study of the dental anomalies involved Nonsyndromic cleft lip and/or palate (NSCL/P) is the most common craniofacial malformation. Due to the anatomical defect present in the alveolar process, these patients tend to exhibit more dental anomalies. The aim of this study was to identify the prevalence of dental anomalies in patients with NSCL/P by obtaining orthodontic documentation from Brazilian Centers for cleft lip and palate treatment.A (...) agenesis was the most common abnormality found in those patients (87.8%) (p<0.001). Also, the largest number of dental anomalies was detected in the group of unilateral left clefts. The prevalence of dental anomalies in the present sample of NSCL/P patients was high and reached the highest levels in patients with alveolar bone clefts.This study describes the most common dental anomalies observed in patients with NSCL/P. These abnormalities can cause significant problems that may be solved or minimized

Full Text available with Trip Pro

2018 Journal of clinical and experimental dentistry

94. One-Stage vs. Two-Stage Repair of Asymmetric Bilateral Cleft Lip: A 20-Year Retrospective Study of Clinical Outcome. (PubMed)

One-Stage vs. Two-Stage Repair of Asymmetric Bilateral Cleft Lip: A 20-Year Retrospective Study of Clinical Outcome. Both one- and two-stage approaches have been widely used for patients with asymmetric bilateral cleft lip. There are insufficient long-term outcome data for comparison of these two methods. The purpose of this retrospective study was to compare the clinical outcome over the past 20 years.The senior author's (L.J.L.) database was searched for patients with asymmetric bilateral (...) cleft lip from 1995 to 2015. Qualified patients were divided into two groups: one-stage and two-stage. The postoperative photographs of patients were evaluated subjectively by surgical professionals and laypersons. Ratios of the nasolabial region were calculated for objective analysis. Finally, the revision procedures in the nasolabial area were reviewed. Statistical analyses were performed.A total of 95 consecutive patients were qualified for evaluation. Average follow-up was 13.1 years. A two

2018 Plastic and reconstructive surgery

95. Efficacy of Maxillo-facial Treatment on Cleft Lip and Palate Patients Faces: Aesthetic Considerations

Efficacy of Maxillo-facial Treatment on Cleft Lip and Palate Patients Faces: Aesthetic Considerations Efficacy of Maxillo-facial Treatment on Cleft Lip and Palate Patients Faces: Aesthetic Considerations - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Efficacy of Maxillo-facial Treatment on Cleft Lip and Palate Patients Faces: Aesthetic Considerations The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03395015 Recruitment Status : Completed First Posted : January 9, 2018 Last Update Posted : January 9

2018 Clinical Trials

96. Cleft lip and palate associated hearing loss in Brazilian children. (PubMed)

Cleft lip and palate associated hearing loss in Brazilian children. Cleft lip and palate children have chronic otitis media related to Eustachian Tube dysfunction and associated conductive hearing loss. In this group of children, communicative skill development limitations, in association with orofacial aesthetics and functional disorders, can lead to behavioral, educational and social problems.We evaluated the minimum hearing threshold and the air-bone gap (ABG) in a range from 500 to 4000 Hz (...) for 4-14 years old cleft lip and palate children (CLPC). This cross-sectional study took place in a multiprofessional tertiary care center and involved 89 CLPC with bilateral or unilateral postforamen or transforamen malformation, divided into two groups: those aged 4-7 and 8-14 years. The hearing tests of 89 children were evaluated: 53 (group I) aged from 4 to 7 years (67.9% male) and 36 (group II) aged from 8 to 14 years (55.6% female).The minimum hearing threshold 500-4 KHz mean (MHT 500-4 KHz

2018 International Journal of Pediatric Otorhinolaryngology

97. Use of Routine Prospective Functional and Aesthetic Patient Satisfaction Measurements in Secondary Cleft Lip Rhinoplasty. (PubMed)

Use of Routine Prospective Functional and Aesthetic Patient Satisfaction Measurements in Secondary Cleft Lip Rhinoplasty. Patients, governments, health care providers, and insurance companies show an increased interest in health outcomes, especially in centralized medical care, such as cleft lip nose treatment. Transparent outcome reporting requires a thorough methodological design, dedicated prospective data collection process, and, preferably, no interference with the efficacy of daily (...) practice.To describe the implementation of an automated and prospective secondary cleft lip rhinoplasty outcome routine.A prospective analytic cohort pilot study was conducted among 123 consecutive patients referred for secondary cleft lip rhinoplasty from July 1, 2014, to March 31, 2018, at an academic teaching hospital.Secondary cleft lip rhinoplasty or revision.Preoperative and 3- and 12-month postoperative scores on the Nasal Obstruction Symptom Evaluation scale (range 0-100, lower scores indicate

2018 JAMA facial plastic surgery

98. "People look and ask lots of questions": caregivers' perceptions of healthcare provision and support for children born with cleft lip and palate. (PubMed)

"People look and ask lots of questions": caregivers' perceptions of healthcare provision and support for children born with cleft lip and palate. Clefting of the lip and/or palate (CL/P) is amongst the five most common birth defects reported in South Africa. The emotional impact on parents at the birth of their new-born with CL/P could affect parent-child relationships. In light of insufficient scholarly attention parental experiences and perceptions, this study reports on caregivers (...) ' perceptions of health service provision and support for children born with cleft lip and palate in South Africa.The study setting consisted of 11 academic hospital centres situated in six of South Africa's nine provinces. At each of the academic centres cleft clinic, five to ten parents or caregivers were selected purposively. Participants were interviewed, using a semi-structured interview schedule that elicited socio-demographic information, explored the family experiences of having a child with CL/P

Full Text available with Trip Pro

2018 BMC Public Health

99. Clefts of the lip and palate: is the Internet a trustworthy source of information for patients? (PubMed)

Clefts of the lip and palate: is the Internet a trustworthy source of information for patients? Great numbers of patients use the Internet to obtain information and familiarize themselves with medical conditions. However, the quality of Internet-based information on clefts of the lip and palate has not yet been examined. The goal of this study was to assess the quality of Internet-based patient information on orofacial clefts. Websites were evaluated based on the modified Ensuring Quality (...) ; the median score was 19 points. The top five high-scoring web pages are highlighted. The overall quality of Internet-based patient information on orofacial clefts is low. Also, the majority of web pages created by medical practitioners have a marketing perspective and in order to attract more patients/customers avoid mentioning the risks of the reconstructive procedures needed.Copyright © 2018 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

2018 International Journal of Oral and Maxillofacial Surgery

100. Caregivers' perception of speech and language status and related needs in children with cleft lip and palate. (PubMed)

Caregivers' perception of speech and language status and related needs in children with cleft lip and palate. Comprehensive management for communication disorders in individuals with CLP was provided in a community based program in two rural districts in Tamilnadu, India. This program provides services at the community to empower the families about CLP and treatment options.To document the caregiver perceptions' of communication status and needs in children with repaired CLP.Six Focus Group

2018 International Journal of Pediatric Otorhinolaryngology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>