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Cleft Lip

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61. Intensive speech therapy in Ugandan patients with cleft (lip and) palate: a pilot-study assessing long-term effectiveness. (PubMed)

Intensive speech therapy in Ugandan patients with cleft (lip and) palate: a pilot-study assessing long-term effectiveness. In resource-limited countries, traditional models for speech therapy delivery are not adequate to reach all patients in need. In those countries, intensive speech therapy might be a solution. Preliminary results of previous research demonstrated that intensive speech therapy can be effective in the short term for patients living in countries with limited access to speech (...) therapy. Questions might arise whether or not intensive treatment results in long-term benefits for these patients. Hence, the present study investigated long-term effectiveness of intensive speech therapy provided to Ugandan patients born with a cleft palate with or without cleft lip (CP ± L) in terms of different speech characteristics.Five Ugandan patients with CP ± L, who received intensive speech therapy in the past, were contacted to participate in this follow-up study. All patients agreed

2019 International Journal of Pediatric Otorhinolaryngology

62. Anatomical patterns of cleft lip and palate deformities among neonates in Mekelle, Tigray, Ethiopia; implication of environmental impact. (PubMed)

Anatomical patterns of cleft lip and palate deformities among neonates in Mekelle, Tigray, Ethiopia; implication of environmental impact. Cleft lip and palate deformities are considered one of the most common birth defects of the head and neck that pose significant medical, psychosocial and financial burdens on the affected individuals and families, especially in low income communities. The etiology and pathogenesis of cleft lip and palate is complex and is known to involve genetic (...) and/or environmental factors.To assess the patterns of anatomical cleft lip and palate deformities among neonates in Mekelle and Ayder Comprehensive Specialized hospitals, Tigray, Northern Ethiopia.A hospital-based retrospective study was conducted from May 2017 to June 2017 at Mekelle and Ayder Comprehensive Specialized hospitals, both in Mekelle city. Data was collected from all medical charts of neonates registered from 2011 to 2016 and analyzed using SPSS version 21.0 and OpenEpi software. Results were

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2019 BMC Pediatrics

63. Child development skills and language in toddlers with cleft lip and palate. (PubMed)

Child development skills and language in toddlers with cleft lip and palate. Children born with cleft lip and palate (CLP) are exposed to several risk factors for developmental delay.This cross-sectional and descriptive study compared the performance of gross motor, adaptive fine motor, social-personal and language skills in children with non-syndromic cleft lip and palate (age = 36-47 months, n = 30) matched as to chronological age and gender. The evaluation instruments were Denver

2019 International Journal of Pediatric Otorhinolaryngology

64. Comparative Evaluation of Dexamethasone and Dexmedetomidine as Adjuvants for Bupivacaine in Ultrasound-Guided Infraorbital Nerve Block for Cleft Lip Repair: A Prospective, Randomized, Double-Blind Study. (PubMed)

Comparative Evaluation of Dexamethasone and Dexmedetomidine as Adjuvants for Bupivacaine in Ultrasound-Guided Infraorbital Nerve Block for Cleft Lip Repair: A Prospective, Randomized, Double-Blind Study. To compare dexamethasone (DA) to dexmedetomidine (DE) as adjuvants for bupivacaine during infraorbital nerve block (IONB) in a randomized clinical trial.One hundred patients were randomized into two equal groups. By the guidance of ultrasound, the IONB was performed bilaterally in all patients (...) 24 h postoperatively, the DE group showed a significantly lower FLACC score and a longer time to first analgesic request compared to DA group. Sedation and parent satisfaction scores were significantly higher while heart rate and mean blood pressure were significantly lower in DE group compared to DA group. There were no differences in other secondary outcomes.The use of DE as an adjuvant to bupivacaine in IONB for cleft lip repair resulted in lower pain score and more prolonged duration

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2019 Anesthesia, essays and researches Controlled trial quality: predicted high

65. Cone beam computed tomography evaluation of ponticulus posticus in patients with cleft lip and palate: a retrospective radio-anatomic study. (PubMed)

Cone beam computed tomography evaluation of ponticulus posticus in patients with cleft lip and palate: a retrospective radio-anatomic study. Ponticulus posticus (PP) is an abnormal bony bridge on the atlas. It plays a significant role in patients undergoing C1 lateral mass screw procedure. Patients with cleft lip and palate (CLP) have higher risk than patients in general population for the appearance of cervical vertebral anomalies. The purpose of the this study was twofold: to determine (...) the prevalence and characteristics of PP in patients with CLP, and to compare the findings with patients in general population using cone beam computed tomography.Cone beam computed tomography images from 54 individuals who had undergone surgical repair of cleft lip and/or palate were analysed as the study group. For comparison purposes a control group was randomly selected from 108 patients and matched with the CLP subjects.Although 12 of the 54 (22.3%) patients with surgically repaired cleft lip

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2019 Folia morphologica Controlled trial quality: uncertain

66. Unilateral cleft lip: evaluation and comparison of treatment outcome with two surgical techniques based on qualitative (subject/guardian and professional) assessment. (PubMed)

Unilateral cleft lip: evaluation and comparison of treatment outcome with two surgical techniques based on qualitative (subject/guardian and professional) assessment. The outcomes of the treatment of unilateral cleft lip can vary considerably due to variations in repair techniques. The aim of this study was to evaluate and compare treatment outcomes of surgical repair of unilateral cleft lip using either the Tennison-Randall or Millard technique based on (qualitative) parent/subject (...) and professional assessments.This was a prospective, randomized, controlled study conducted at Lagos University Teaching Hospital between January 2013 and July 2014. A total of 56 subjects with unilateral cleft lip presenting for primary surgery who satisfied the inclusion criteria were recruited for the study. Subjects were randomly allocated to surgical groups A or B through balloting. Group A underwent cleft repair with the Tennison-Randall technique, while group B underwent cleft repair with the Millard

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2019 Journal of the Korean Association of Oral and Maxillofacial Surgeons Controlled trial quality: uncertain

67. [Ketamine as an adjunct to bupivacaine in infra-orbital nerve block analgesia after cleft lip repair]. (PubMed)

[Ketamine as an adjunct to bupivacaine in infra-orbital nerve block analgesia after cleft lip repair]. We conducted this study to investigate the safety and analgesic efficacy of the addition of Ketamine to Bupivacaine in bilateral extra-oral infra-orbital nerve block in children undergoing cleft lip surgeries.Sixty patients were randomly allocated into two groups (n=30), Group B received infra-orbital nerve block with 2mL of 0.25% Bupivacaine and Group BK received 0.5mg.kg-1 Ketamine for each (...) ) and in the first hour (h) postoperatively (1.40±0.17 vs. 0.67±0.14, p<0.003). Higher parent satisfaction scores were recorded in Group BK (p<0.04) without significant adverse effects.The addition of Ketamine to Bupivacaine has accentuated the analgesic efficacy of infra-orbital nerve block in children undergoing cleft lip repair surgeries.Copyright © 2018 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

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2019 Revista brasileira de anestesiologia Controlled trial quality: uncertain

68. Tooth-borne distraction osteogenesis versus conventional Le Fort I in maxillary advancement of cleft lip and palate patients. (PubMed)

Tooth-borne distraction osteogenesis versus conventional Le Fort I in maxillary advancement of cleft lip and palate patients. Distraction osteogenesis (DO) is rapidly becoming a mainstream surgical technique for correction of maxillary deficiency. The aim of this study was to compare the effectiveness of a newly designed tooth-borne osteogenic distraction device with conventional Le Fort 1 osteotomy in maxillary advancement of cleft lip and palate patients.The DO group consisted of 10 subjects (...) osteogenic distraction device can effectively advance the maxilla forward in patients with cleft lip.

2019 Minerva stomatologica Controlled trial quality: uncertain

69. Correction of labial tubercle defect in repaired bilateral cleft lips using bilateral vermilion musculomucosal sliding flaps: Case series. (PubMed)

Correction of labial tubercle defect in repaired bilateral cleft lips using bilateral vermilion musculomucosal sliding flaps: Case series. Insignifificant, asymmetrical or lack of labial tubercle often occurs after cleft lip surgery due to improper treatment of vermilion tissue. Especially in the cases of bilateral cleft lip, because of short front lip and insuffificient vermilion tissue, the median vermilion depression often occurs after surgery, forming a "whistling" deformity. The object (...) of this study is to verify the outcomes of patients with median labial tubercle detects after treatment with bilateral vermilion musculomucosal sliding flflaps (VMSF).Six patients with median labial tubercle defect after bilateral cleft lip repair from March 2015 to May 2017 were enrolled in our department and subjected to bilateral lip deformity correction under general anesthesia.Secondary deformity of bilateral cleft lip forming a "whistling" deformity were diagnosed in all the patients.Bilateral VMSF

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2019 Medicine

70. Unilateral cleft lip nasal deformity: 3D analysis of the primary deformity and longitudinal changes following primary correction of the nasal foundation. (PubMed)

Unilateral cleft lip nasal deformity: 3D analysis of the primary deformity and longitudinal changes following primary correction of the nasal foundation. Objective assessment of the unilateral cleft lip nasal deformity and the longitudinal changes with treatment is critical to optimizing cleft care. We used 3D images to evaluate nasal base morphology.Consecutive patients undergoing cleft lip repair and foundation-based rhinoplasty were included (N=102). 3D images pre-op, post-op, and at 5 years (...) displacement of non-cleft subalare, narrowing of non-cleft nostril, and intercanthal widening. Surgery corrected nasal base displacements along all axes resulting in landmark positions similar to controls. The symmetry of nasal base correction persisted at 5-year follow-up with no recurrent cleft alar base retrusion, regardless of initial cleft type.Unilateral cleft lip nasal deformity may be 'driven' by displacement of anterior nasal spine and caudal septum. The cleft alar base is normal in position

2019 Plastic and reconstructive surgery

71. Association of Pediatric Patient Demographic Factors and Scar Anatomic Features With Scar Outcomes After Surgical Repair of Cleft Lip. (PubMed)

Association of Pediatric Patient Demographic Factors and Scar Anatomic Features With Scar Outcomes After Surgical Repair of Cleft Lip. Scar outcomes following cleft lip repair are an important component of pediatric patient and family satisfaction and indicate the need for future surgical interventions.To assess the association of pediatric patient demographic factors and scar anatomic features with scar outcomes following cleft lip surgical repair.A case-control study was conducted involving (...) 58 pediatric patients who underwent surgical repair of a cleft lip from October 31, 2008, to August 4, 2016, at a tertiary care pediatric specialty hospital. Data on patient demographic factors, cleft type, and the surgical technique used were collected and analyzed from June 11, 2009, to November 21, 2017. Scar outcomes were subjectively rated by 3 physicians at 6-month and 12-month postoperative intervals.Overall scar outcomes at 6-month and 12-month postoperative intervals were based on rating

2019 JAMA facial plastic surgery

72. Lipofilling in patients with a cleft lip (and palate) - a pilot study assessing functional outcomes and patients' satisfaction with appearance. (PubMed)

Lipofilling in patients with a cleft lip (and palate) - a pilot study assessing functional outcomes and patients' satisfaction with appearance. Lipofilling of the upper lip as secondary treatment in patients with a cleft lip (and palate) (CL ± P) has been proposed to improve projection and volume especially in profile view. The purpose of the present study was to document differences in functional (i.e. logopaedic) and self-reported aesthetic outcomes by comparing pre- and postoperative results (...) after lipofilling of the upper lip in patients with CL ± P.Eight Dutch-speaking youngsters and young adults (three women, five men) with CL ± P were included. The median age was 19 years (range: 14-24 years). Logopaedic outcomes (i.e. assessment of orofacial myofunctional behavior, articulation and lip strength) and self-reported aesthetic outcome (i.e. patients' satisfaction using the Cleft Evaluation Profile) were determined.Neither for lip strength and orofacial myofunctional behavior nor

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2019 International Journal of Pediatric Otorhinolaryngology

73. The impact of cleft lip and/or palate on parental quality of life: A pilot study. (PubMed)

The impact of cleft lip and/or palate on parental quality of life: A pilot study. Cleft lip and/or palate (CL/CP/CLP) is one of the most common congenital anomalies. Children may suffer from a variety of health problems including difficulties with feeding and speech, middle ear problems, hearing loss and associated psychosocial concerns. The extent of impact of this disorder on the parents, however, has not yet been thoroughly evaluated. This pilot study was performed to evaluate the impact (...) of having a child with CL/CP/CLP on the parents' quality of life (QoL) and family functioning and to compare between cleft subgroups.Forty-five parents with children aged 6 months to 6 years with CL/CP/CLP, followed by the multidisciplinary orofacial cleft team of Ghent University Hospital, completed following standardized questionnaires: Impact on Family Scale (IOFS), Family Impact Scale (FIS) and Care-Related Quality of Life Instrument (CarerQoL). Subgroups were compared with diverse unpaired

2019 International Journal of Pediatric Otorhinolaryngology

74. Acoustic analysis of voice in children with cleft lip and palate following vocal rehabilitation. Preliminary report. (PubMed)

Acoustic analysis of voice in children with cleft lip and palate following vocal rehabilitation. Preliminary report. Cleft lip and palate (CLP) is the most common craniofacial anomaly. CLP affects resonance, voice and speech. Besides the most frequently reported resonance and speech disorders, several reports have addressed acoustic abnormalities in the voice of patients with CLP. However, there are just a few reports focusing on vocal treatment in this population.To study whether a Speech (...) and Language Pathology (SLP) intervention including vocal rehabilitation for children with CLP and velopharyngeal insufficiency (VPI) provides significant improvement of abnormal acoustic parameters of voice.Fifteen children with cleft lip and palate (CLP) and velopharyngeal insufficiency (VPI) were studied. Age ranged 4-5 years. A matched control group of children without craniofacial anomalies and adequate speech, resonance and voice was assembled. All children underwent acoustic analysis of voice

2019 International Journal of Pediatric Otorhinolaryngology

75. Pre-Surgical Infant Orthopedics (PSIO) And Naso-Alveolar Molding (NAM) Show Promise For Obtaining Normal Anatomy Of The Nose And Lip In Patients With Cleft Lip And Palate

Pre-Surgical Infant Orthopedics (PSIO) And Naso-Alveolar Molding (NAM) Show Promise For Obtaining Normal Anatomy Of The Nose And Lip In Patients With Cleft Lip And Palate UTCAT2163, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Pre-Surgical Infant Orthopedics (PSIO) And Naso-Alveolar Molding (NAM) Show Promise For Obtaining Normal Anatomy Of The Nose And Lip In Patients With Cleft Lip And Palate Clinical Question (...) In a child with cleft lip and palate, is there long-term benefit to pre-surgical naso-alveolar molding versus traditional surgical treatment alone? Clinical Bottom Line Long-term anthropologic studies comparing NAM to traditional treatment show equivocal results; however, pre-surgical infant orthopedics (PSIO) is gaining a body of literature to support it’s use. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1

2011 UTHSCSA Dental School CAT Library

76. Patients With Cleft Lip, Alveolus And Palate May Be Predisposed To Periodontal Disease, Especially In Teeth Adjacent To The Cleft

Patients With Cleft Lip, Alveolus And Palate May Be Predisposed To Periodontal Disease, Especially In Teeth Adjacent To The Cleft UTCAT2160, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Patients With Cleft Lip, Alveolus And Palate May Be Predisposed To Periodontal Disease, Especially In Teeth Adjacent To The Cleft Clinical Question Do patients with repaired cleft lip, alveolus, and palate have increased risk (...) of periodontal disease compared to normal subjects? Clinical Bottom Line While studies suggest that patient with cleft lip, palate and alveolus are predisposed to periodontal disease, especially in teeth near the cleft, further studies are required given lack of definitive evidence. Oral hygiene was also found to be poor in a majority of patients with cleft lip, alveolus, or palate, emphasizing the importance of good oral hygiene and close followup with these patients. Best Evidence (you may view more info

2011 UTHSCSA Dental School CAT Library

77. Surgical correction of upper lip deficit in patients with cleft lip using dermis fat graft (PubMed)

Surgical correction of upper lip deficit in patients with cleft lip using dermis fat graft This study aimed to assess dermis fat graft (DFG) as a choice to correct the tissue deficit in the free border of the upper lip in cleft lip repair surgery.Thirty-five individuals who referred to Alzahra Hospital at 2013-2014, with lip deformity following the primary repair surgery of cleft lip underwent surgery by DFG technique. Outcomes were assessed 4 months after the surgery based on comparison (...) of preoperative and postoperative photographs.The results in 18 (51.42%) patients were excellent, 10 (28.57%) good, and 7 (20%) intermediate according to the satisfaction of patients and investigators in terms of filling of lip deficit and motion of the upper lip. Moreover, complications and pain were minimal after 4-month follow-up.This method introduces an admissible method with 80% good to excellent results based on satisfactory of patients and surgeon.

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2017 Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

78. Perioperative analgesia for children undergoing primary cleft lip and palate repair: a systematic review and meta-analysis

Perioperative analgesia for children undergoing primary cleft lip and palate repair: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence

2018 PROSPERO

79. Maxillary protraction in cleft lip and palate patients: a systematic review

Maxillary protraction in cleft lip and palate patients: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing and effect

2018 PROSPERO

80. Bacteria profile of patients with and without cleft lip and/or palate undergoing orthodontic treatment: a systematic review and meta-analysis

Bacteria profile of patients with and without cleft lip and/or palate undergoing orthodontic treatment: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2018 PROSPERO

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