How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

8,059 results for

Chronic Cough

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Speech and language therapy for management of chronic cough. (PubMed)

Speech and language therapy for management of chronic cough. Cough both protects and clears the airway. Cough has three phases: breathing in (inspiration), closure of the glottis, and a forced expiratory effort. Chronic cough has a negative, far-reaching impact on quality of life. Few effective medical treatments for individuals with unexplained (idiopathic/refractory) chronic cough (UCC) are known. For this group, current guidelines advocate the use of gabapentin. Speech and language therapy (...) is needed to understand which aspects of SLT interventions are most effective in reducing cough (both objective cough frequency and subjective measures of cough) and improving HRQoL. We consider these endpoints to be clinically important. It is also important for future studies to report information on adverse events.Because of the paucity of data, we can draw no robust conclusions regarding the efficacy of SLT interventions for improving outcomes in unexplained chronic cough. Our review identifies

2019 Cochrane

4. Assessment of chronic cough

Assessment of chronic cough Assessment of chronic cough - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of chronic cough Last reviewed: February 2019 Last updated: June 2018 Summary Cough is the most common presenting symptom in primary practice. Schappert SM, Burt CW. Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 2001-02. Vital (...) Health Stat 13. 2006 Feb;(159):1-66. http://www.cdc.gov/nchs/data/series/sr_13/sr13_159.pdf http://www.ncbi.nlm.nih.gov/pubmed/16471269?tool=bestpractice.com Sub-acute cough is defined as cough persisting for 3 to 8 weeks, and chronic cough as that persisting for more than 8 weeks. Irwin RS, French CL, Chang AB, et al. Classification of cough as a symptom in adults and management algorithms: CHEST guideline and expert panel report. Chest. 2018 Jan;153(1):196-209. http://journal.chestnet.org/article

2018 BMJ Best Practice

5. Cough Due to Tuberculous and Other Chronic Infections

Cough Due to Tuberculous and Other Chronic Infections Cough Due to TB and Other Chronic Infections CHEST Guideline and Expert Panel Report Stephen K. Field, MD,CM, FCCP; Patricio Escalante, MD, FCCP; Dina A. Fisher, MD, FCCP; Belinda Ireland, MD; Richard S. Irwin, MD, Master FCCP; on behalf of the CHEST Expert Cough Panel BACKGROUND: Cough is common in pulmonary TB and other chronic respiratory infections. Identifying features that predict whether pulmonary TB is the cause would help target (...) not yet been performed (Ungraded Consensus-Based Statement). 10. For patients with chronic cough in low income countries,wesuggestthatstrategiesforpulmonaryTB diagnosis should focus on improved case detection rather than diagnostic testing (Ungraded Consensus- Based Statement). Approximately 9.6 million people developed active TB worldwide in 2014, and 1.5 million died as a result. 1 The consequences of TB are greatest in the developing world where the prevalence is greatest and resources to diagnose

2018 American College of Chest Physicians

6. Chronic Cough Related to Acute Viral Bronchiolitis in Children

Chronic Cough Related to Acute Viral Bronchiolitis in Children Chronic Cough Related to Acute Viral Bronchiolitis in Children CHEST Expert Panel Report Anne B. Chang, MBBS, PhD, MPH; John J. Oppenheimer, MD; Bruce K. Rubin, MD; Miles Weinberger, MD, FCCP; and Richard S. Irwin, MD, Master FCCP; on behalf of the CHEST Expert Cough Panel BACKGROUND: Acute bronchiolitis is common in young children, and some children develop chronic cough after their bronchiolitis. We thus undertook systematic (...) reviews based on key questions (KQs) using the PICO (Population, Intervention, Comparison, Outcome) format. The KQs were: Among children with chronic cough (> 4 weeks) after acute viral bron- chiolitis, how effective are the following interventions in improving the resolution of cough?: (1) Antibiotics. If so what type and for how long? (2) Asthma medications (inhaled steroids, beta 2 agonist, montelukast); and (3) Inhaled osmotic agents like hypertonic saline? METHODS: We used the CHEST expert cough

2018 American College of Chest Physicians

7. [Fractional exhaled nitric oxide measurement in patients with asthma and chronic cough]

[Fractional exhaled nitric oxide measurement in patients with asthma and chronic cough] [Fractional exhaled nitric oxide measurement in patients with asthma and chronic cough] [Fractional exhaled nitric oxide measurement in patients with asthma and chronic cough] Virgilio S, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation (...) of the quality of this assessment has been made for the HTA database. Citation Virgilio S, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A. [Fractional exhaled nitric oxide measurement in patients with asthma and chronic cough] Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Documentos de Evaluación de Tecnologías Sanitarias, Informe de Respuesta Rapida No 536. 2017 Authors' conclusions Moderate quality evidence suggests that fractional exhaled

2017 Health Technology Assessment (HTA) Database.

8. Codeine versus placebo for chronic cough in children. (PubMed)

Codeine versus placebo for chronic cough in children. Cough in children is a commonly experienced symptom that is associated with increased health service utilisation and burden to parents. The presence of chronic (equal to or more than four weeks) cough in children may indicate a serious underlying condition such as inhaled foreign body or bronchiectasis. Codeine (and derivative)-based medications are sometimes used to treat cough due to their antitussive properties. However (...) , there are inherent risks associated with the use of these medications such as respiratory drive suppression, anaesthetic-induced anaphylaxis, and addiction. Metabolic response and dosage variability place children at increased risk of experiencing such side effects. A systematic review evaluating the quality of the available literature would be useful to inform management practices.To evaluate the safety and efficacy of codeine (and derivatives) in the treatment of chronic cough in children.We searched

Full Text available with Trip Pro

2016 Cochrane

9. Impaired cough suppression in chronic refractory cough. (PubMed)

Impaired cough suppression in chronic refractory cough. Functional brain imaging in individuals with chronic cough demonstrates reduced activation in cortical regions associated with voluntary cough suppression. Little is known about the ability of patients with chronic cough to suppress cough. This study aimed to compare the ability to voluntarily suppress cough during inhaled capsaicin challenge in participants with chronic refractory cough with that in healthy controls. This study also aimed (...) to assess the repeatability of capsaicin challenge test with voluntary cough suppression.Participants with chronic refractory cough and healthy controls underwent inhaled capsaicin challenge tests whilst attempting to suppress their cough responses. After 5 days either a conventional capsaicin challenge test with no cough suppression attempt, or a repeat test with an attempt at cough suppression was performed. Threshold capsaicin concentrations required to elicit 1, 2 and 5 coughs were calculated

2019 European Respiratory Journal

10. Subfreezing air as a cough trigger and multiple triggers are strongly associated with the presence of asthma in chronic cough. (PubMed)

Subfreezing air as a cough trigger and multiple triggers are strongly associated with the presence of asthma in chronic cough. Management of chronic cough relies on the recognition of cough background disorders. It is not known whether certain cough triggers are associated with specific background disorders.This was an e-mail study to public service employees of two towns in Finland. The questionnaire included twelve triggers. Current asthma was defined as doctor's diagnosis of asthma (...) and current wheezing. Chronic rhinosinusitis was defined as either nasal blockage or nasal discharge and either facial pain/pressure or reduction/loss of smell for more than three months. Gastroesophageal reflux disease was defined as heartburn and/or regurgitation on at least one day a week during the last three months. Idiopathic cough was defined as absence of any of them.There were 421 subjects with current cough that had lasted at least eight weeks. Subfreezing air as a cough trigger was associated

2019 Respiratory medicine

11. Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough. (PubMed)

Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough. The differential sensitivity of cough to antitussive therapies implies the existence of heterogeneity in cough hypersensitivity, but how such heterogeneity is expressed across individual patients is poorly understood. We investigated the phenotypes of cough hypersensitivity by examining transient receptor potential ankyrin 1 (TRPA1)- and transient receptor potential vanilloid 1 (TRPV1 (...) )-mediated cough sensitivity in patients with chronic refractory cough.Using a selective TRPA1 agonist, allyl isothiocyanate (AITC), we established an AITC cough challenge as a measure of TRPA1-mediated cough sensitivity. The AITC cough challenge and the widely used capsaicin (a selective TRPV1 agonist) cough challenge were performed with 250 patients with chronic refractory cough and 56 healthy subjects. The concentration of AITC or capsaicin solution causing at least two (C2) and five coughs (C5

Full Text available with Trip Pro

2019 Respiratory research

12. Typical symptoms and not positive reflux-cough correlation predict cure of gastroesophageal reflux disease related chronic cough after laparoscopic fundoplication: a retrospective study. (PubMed)

Typical symptoms and not positive reflux-cough correlation predict cure of gastroesophageal reflux disease related chronic cough after laparoscopic fundoplication: a retrospective study. The effect of laparoscopic fundoplication on reflux-related chronic cough is unpredictable, the aim of the study is to investigate the predictive effect of positive reflux-cough correlation on the resolution of reflux-related chronic cough after anti-reflux surgery.A 5 years retrospective review was performed (...) . Logistic regression analysis was used to determine the independent predictors on the cure of chronic cough.Seventy-nine patients were included in this study, among which chronic cough was cured in 47 (59.5%) and significantly improved in 10 (12.7%) patients. Present of typical symptoms (odds ratio = 6.435,95% confidence interval [CI] = 1.427-29.032, p = 0.015) and number of Reflux episodes (impedance) ≥73 (odds ratio = 0.306, 95% confidence interval [CI] = 0.107-0.874, p = 0.027) were significantly

2019 BMC Gastroenterology

13. Cough presentation in primary care and the identification of chronic cough: a need for diagnostic clarity? (PubMed)

Cough presentation in primary care and the identification of chronic cough: a need for diagnostic clarity? Objective: To investigate patterns of presentation of cough in primary care and develop an algorithm to identify probable and possible chronic cough (CC). Methods: This retrospective observational study used routine English primary care data and linked hospital data. Patients with ≥1 cough event in the study period (March 2014-February 2015) were selected. Index date (...) %) and 137,718 (91.7%) were classified as having probable CC, possible CC or acute cough, respectively. Compared with probable CC and acute cough, a higher percentage of possible CC cases had a record on or prior to index date indicative of chronic obstructive pulmonary disease (30.6% versus 10.1% and 9.7%), gastro-esophageal reflux disease (32.6% versus 24.9% and 21.1%) or asthma (45.9% versus 27.6% and 27.9%). Prevalences of probable and possible CC were 0.18% and 1.2%, respectively. Conclusions

2019 Current medical research and opinion

14. Use of management pathways or algorithms in children with chronic cough: CHEST guideline and Expert Panel report.

Use of management pathways or algorithms in children with chronic cough: CHEST guideline and Expert Panel report. Use of management pathways or algorithms in children with chronic cough: CHEST guideline and Expert Panel report. | National Guideline Clearinghouse success fail JUN 09 2017 2018 2019 14 Apr 2018 - 12 Jul 2018 COLLECTED BY Organization: Formed in 2009, the Archive Team (not to be confused with the archive.org Archive-It Team) is a rogue archivist collective dedicated to saving (...) of management pathways or algorithms in children with chronic cough: CHEST guideline and Expert Panel report. Chang AB, Oppenheimer JJ, Weinberger MM, Rubin BK, Weir K, Grant CC, Irwin RS, CHEST Expert Cough Panel. Use of management pathways or algorithms in children with chronic cough: CHEST guideline and Expert Panel report. Chest. 2017 Apr;151(4):875-83. [48 references] This is the current release of the guideline. This guideline meets NGC's 2013 (revised) inclusion criteria. Age Group UMLS Concepts

2017 National Guideline Clearinghouse (partial archive)

15. Management of children with chronic wet cough and protracted bacterial bronchitis: CHEST guideline and Expert Panel report.

Management of children with chronic wet cough and protracted bacterial bronchitis: CHEST guideline and Expert Panel report. Management of children with chronic wet cough and protracted bacterial bronchitis: CHEST guideline and Expert Panel report. | National Guideline Clearinghouse success fail JUN 10 2017 2018 2019 14 Apr 2018 - 13 Jul 2018 COLLECTED BY Organization: Formed in 2009, the Archive Team (not to be confused with the archive.org Archive-It Team) is a rogue archivist collective (...) of children with chronic wet cough and protracted bacterial bronchitis: CHEST guideline and Expert Panel report. Chang AB, Oppenheimer JJ, Weinberger MM, Rubin BK, Grant CC, Weir K, Irwin RS, CHEST Expert Cough Panel. Management of children with chronic wet cough and protracted bacterial bronchitis: CHEST guideline and Expert Panel report. Chest. 2017 Apr;151(4):884-90. [33 references] This is the current release of the guideline. This guideline updates a previous version: Chang AB, Glomb WB. Guidelines

2017 National Guideline Clearinghouse (partial archive)

16. Chronic Cough and Gastroesophageal Reflux in Children: CHEST Guideline and Expert Panel Report

Chronic Cough and Gastroesophageal Reflux in Children: CHEST Guideline and Expert Panel Report Whether gastroesophageal reflux (GER) or GER disease (GERD) causes chronic cough in children is controversial. Using the Population, Intervention, Comparison, Outcome (PICO) format, we undertook four systematic reviews. For children with chronic cough (> 4-weeks duration) and without underlying lung disease: (1) who do not have gastrointestinal GER symptoms, should empirical treatment for GERD be used (...) ? (2) with gastrointestinal GER symptoms, does treatment for GERD resolve the cough? (3) with or without gastrointestinal GER symptoms, what GER-based therapies should be used and for how long? (4) if GERD is suspected as the cause, what investigations and diagnostic criteria best determine GERD as the cause of the cough?We used the CHEST Expert Cough Panel's protocol and American College of Chest Physicians (CHEST) methodological guidelines and GRADE (Grading of Recommendations Assessment

2019 EvidenceUpdates

17. Cough (acute): antimicrobial prescribing

are viral infections. It can also be caused by acute bronchitis, a lower respiratory tract infection, which is usually a viral infection but can be bacterial. Other infective causes of cough include pneumonia, acute exacerbations of asthma, chronic obstructive pulmonary disease or bronchiectasis (which may also be non-infective exacerbations), and viral-induced wheeze, bronchiolitis, croup or whooping cough. Non-infective causes may include lung cancer, a foreign body, interstitial lung disease (...) Cough (acute): antimicrobial prescribing Cough (acute Cough (acute): antimicrobial prescribing ): antimicrobial prescribing NICE guideline Published: 7 February 2019 nice.org.uk/guidance/ng120 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

18. Prevalence of Arnold nerve reflex in subjects with and without chronic cough: Relevance to Cough Hypersensitivity Syndrome. (PubMed)

Prevalence of Arnold nerve reflex in subjects with and without chronic cough: Relevance to Cough Hypersensitivity Syndrome. Cough is induced by stimulation of structures innervated by the vagus nerve, including the upper and lower airways and distal esophagus. The Arnold nerve reflex describes cough resulting from stimulation of the external auditory canal, which is innervated by the auricular branch of the vagus. We have recently reported the increased prevalence of this reflex in adults (...) , but not children, with chronic cough, relative to healthy adult and pediatric subjects. The prevalence of the Arnold nerve reflex in patients with pulmonary disease but without chronic cough has not been investigated previously.Three hundred adults and 100 children with chronic cough, 50 adults with stable pulmonary disease but without chronic cough, as well as 100 adult and 100 pediatric volunteers, underwent evaluation consisting of stimulation of the external auditory canal of each ear with a cotton-tipped

2018 Pulmonary Pharmacology & Therapeutics

19. Assessing referral and practice patterns of patients with chronic cough referred for behavioral cough suppression therapy. (PubMed)

Assessing referral and practice patterns of patients with chronic cough referred for behavioral cough suppression therapy. The purpose of this exploratory research was to describe current referral and practice patterns for behavioral cough suppression therapy (BCST) throughout the United States, and to assess the need for improving the efficiency of BCST referral patterns. In study I, 126 speech-language pathologists, who treat patients with refractory chronic cough (RCC) in the United States (...) , completed a survey about referral patterns, cough duration, and patient frustration level. In study II, 36 adults with RCC referred for BCST completed a four-part survey about cough symptoms and treatment. The survey included the Leicester Cough Questionnaire (LCQ) before and after BCST. Study I revealed significant patient frustration about the treatment process and the wait-time for BCST. Participants in study II reported average cough duration of over 2 years before BCST. Twenty-seven of 31

Full Text available with Trip Pro

2018 Chronic respiratory disease

20. Association of cough hypersensitivity with tracheal TRPV1 activation and neurogenic inflammation in a novel guinea pig model of citric acid-induced chronic cough (PubMed)

Association of cough hypersensitivity with tracheal TRPV1 activation and neurogenic inflammation in a novel guinea pig model of citric acid-induced chronic cough Objective This study was performed to establish a novel model of citric acid-induced chronic cough in guinea pigs and to investigate the pathogenesis of cough hypersensitivity. Methods Healthy conscious guinea pigs inhaled citric acid (0.4 M) for 3 minutes twice daily for 25 days. Cough reactivity was evaluated, substance P (SP (...) expression. TRPV1 was mainly observed in the mucosal and submucosal layer of the trachea and bronchi. The areas of TRPV1 positivity in the trachea and bronchi of citric acid-treated animals were significantly larger than in the control group. Conclusions Repeated inhalation of citric acid can be employed to establish a chronic cough model in guinea pigs. Cough hypersensitivity in this model is related to tracheal TRPV1 activation and neurogenic inflammation.

Full Text available with Trip Pro

2018 The Journal of international medical research

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>