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161. Adipose Tissue Function and Response to Exercise Training in Women With and Without Polycystic Ovary Syndrome

with and without polycystic ovary syndrome (PCOS). PCOS is a common endocrine disorder in young women. The pathogenesis behind PCOS is complex and only partly understood, and deeper mechanistic insight is needed. Insulin resistance is a central feature of PCOS, and recent studies have suggested that this is linked to aberrant adipose tissue function. Exercise training has been found to improve the symptoms in PCOS, but we need more knowledge about why. While processes involved in skeletal muscle oxidative (...) to Exercise Training in Women With and Without Polycystic Ovary Syndrome Actual Study Start Date : October 24, 2016 Estimated Primary Completion Date : May 2019 Estimated Study Completion Date : May 2019 Resource links provided by the National Library of Medicine related topics: related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: 4x4 minutes interval training 4x4 minutes high intensity interval training with 4 minute intervals Behavioral: 4x4 minutes high intensity

2016 Clinical Trials

162. Internet Based Exercise Training in Type 2 Diabetes

(Clinical Trial) Actual Enrollment : 61 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Outcomes Assessor) Primary Purpose: Treatment Official Title: Can Internet Based Exercise Training Be an Alternative to Supervised Group Exercise Training in Patients With Type 2 Diabetes? Actual Study Start Date : April 2015 Actual Primary Completion Date : June 2016 Actual Study Completion Date : September 1, 2016 Resource links provided by the National Library (...) and right) [ Time Frame: 2 months ] Euro Quality of Life-5 Dimension [ Time Frame: 2 months ] Other Outcome Measures: cholesterol levels [ Time Frame: 2 months ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided

2016 Clinical Trials

163. PeRioperative Study of Exercise Training in Patients With Operable Cancer of the Gastroesophageal Junction

: May 2018 Resource links provided by the National Library of Medicine related topics: resources: Arms and Interventions Go to Arm Intervention/treatment No Intervention: Usual Care Observation Group Patients allocated to usual care control will receive the standard patient care program as provided by the department of surgical gastroenterology, Rigshospitalet Experimental: Aerobic and Resistance Exercise Training Patients allocated to this group will receive usual care plus a supervised aerobic (...) and recorded for the given visit. Also, for each trial visit we will collect patients' self-report of AE/SAEs, which may have occurred during the period since the last trial visit without our knowledge. AE/SAE recording during exercise sessions For every exercise session, a trained instructor will supervise the exercise program including recording of AE/SAEs during these session Adherence to prescribed exercise program [ Time Frame: Baseline to 3 months post surgery ] Proportion of exercise sessions

2016 Clinical Trials

164. Intensity Training and Cardiovascular Health in Colombian Adults

and Cardiovascular Health in Adults: Effect of Postprandial Period Study Start Date : June 2015 Actual Primary Completion Date : October 2016 Actual Study Completion Date : October 2016 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: High Intensity Interval Training Walking on a treadmill 4min at 80-90% peak heart rate and recovery 4 min at 65% peak heart rate until expenditure of 300 kcal until the end of training (...) Intensity Training and Cardiovascular Health in Colombian Adults Intensity Training and Cardiovascular Health in Colombian Adults - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Intensity Training

2016 Clinical Trials

165. Training in the Fasted State, Glucose Metabolism and Energy Balance

concentrations [ Time Frame: Basal Concentrations - (change after 6 weeks) ] Fasting plasma HDL cholesterol concentrations (mmol/L) Fasting plasma LDL cholesterol concentrations [ Time Frame: Basal Concentrations - (change after 6 weeks) ] Fasting plasma LDL cholesterol concentrations (mmol/L) Fasting plasma non-esterified fatty acid concentrations [ Time Frame: Basal Concentrations - (change after 6 weeks) ] Fasting plasma non-esterified fatty acid concentrations (mmol/L) Waist to hip ratio [ Time Frame (...) Type : Interventional (Clinical Trial) Actual Enrollment : 30 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Basic Science Official Title: Training in the Fasted State, Glucose Metabolism and Energy Balance Actual Study Start Date : September 2016 Actual Primary Completion Date : August 2018 Estimated Study Completion Date : September 2019 Resource links provided by the National Library of Medicine related topics: Arms

2016 Clinical Trials

166. High-Intensity Interval Training on Pre-Hypertensive Subjects

-Term Training: Effects of 16-Week High-Intensity Interval Training on Pre-Hypertensive Subjects Study Start Date : March 2015 Actual Primary Completion Date : December 2016 Actual Study Completion Date : February 2017 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: High Intensity Interval Training Cycling on cycle ergometers (OXFORDTM, model BE2601, OXOFORD Inc, Santiago, Chile) for 1 min (...) High-Intensity Interval Training on Pre-Hypertensive Subjects High-Intensity Interval Training on Pre-Hypertensive Subjects - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. High-Intensity Interval Training

2016 Clinical Trials

167. Exercise Training Effects on Metabolic Syndrome: Interactions With Medication

). Other Outcome Measures: Rates of appearance, dissapearance of glycerol and palmitate in blood. [ Time Frame: 6 months ] Infusion of stable isotope of 13C palmitate and measurement of enrichment in blood of 12/13C palmitate using gas chromatography-mass spectrometry (Hewlett Packard 5971). Rates of oxidation of plasma and intracellular free fatty acids. [ Time Frame: 6 months ] Analysis of enrichment of 13CO2 collected in expired air using isotope ratio-mass spectrometry (IRMS). Eligibility Criteria (...) dysfunction using reactive hyperemia with a laser Doppler fluxmeter in central and peripheral blood vessels. The metabolic adaptations under study will include, i) insulin resistance measured by IVGTT, ii) fat oxidation by indirect calorimetry, iii) intramuscular proteins involved in energetics by percutaneous muscle biopsy and western blots, iv) mitochondria biogenesis by activity of citrate synthase and v) stable-isotopic study of glucose and free fatty acids kinetics in blood (using gas-chromatography

2016 Clinical Trials

168. The Effects of Exercise Training in Community-dwelling Elderly With Sleep Disturbances With Follow-up

and possible mechanisms of a 24-week exercise training for sleep disturbances patients. Sixty patients with sleep disturbances elders will be randomized to exercise group or control group. Participants in the exercise group will receive aerobic and resistance exercise 3 times per week for 24 weeks. The controls will receive sleep hygiene education and consultation. All measurements will be performed as described before. Finally, all the 260 elders participating in this study will receive 12-month follow-up (...) : January 2020 Estimated Study Completion Date : January 2020 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Exercise training group Exercise group will attend a supervised aerobic plus resistance exercise training class 3 times a week totally for 24 weeks. Other: Exercise training group The conditioning period (24 weeks) of the exercise intervention was under the supervision of an exercise physiologist

2016 Clinical Trials

169. Individual Variability to Aerobic Exercise Training

Individual Variability to Aerobic Exercise Training Individual Variability to Aerobic Exercise Training - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Individual Variability to Aerobic Exercise Training (...) Study Description Go to Brief Summary: The purpose of this study is to: 1) determine the cohort specific technical error to use in the categorization of response rate; 2) determine if an individualized intensity prescription is superior to a standard approach in regards to VO2max and cardiometabolic risk factor responsiveness; 3) Investigate the time course changes throughout 12 weeks of CRF training between an individualized and standardized exercise prescription; and 4) determine if non-responders

2016 Clinical Trials

170. Exercise Training and Hepatic Metabolism in Overweight/Obese Adolescent

: resources: Arms and Interventions Go to Arm Intervention/treatment Experimental: Low physical activity program Three Physical Education sessions / week Behavioral: Low physical activity program Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional. Experimental: High physical activity program Three Physical Education sessions / week (increased volume) Behavioral: High physical activity program Exercise will be performed (...) at three sessions per week. All sessions will be supervised by a trained health or exercise professional. Experimental: Low and High physical activity program Three Physical Education sessions / week (increased volume and intensity) Behavioral: Low and High physical activity program Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional. Active Comparator: Conventional physical activity program One Physical Education sessions

2016 Clinical Trials

171. Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans

Date : May 2019 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment No Intervention: Control This group does not change physical activity during the intervention period, but will receive exercise training after the study is complete Experimental: MOD-INT The Moderate intensity exercise training (MOD-INT) group will exercise at a moderate aerobic exercise intensity for 24 weeks Behavioral: Moderate intensity exercise (...) Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans Effects of Exercise Training Intensity on Fitness and Insulin Sensitivity in African Americans - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2016 Clinical Trials

172. Effect of Statins on Trained Immunity

Drug: Statin Detailed Description: Rationale: The innate immune system plays a pivotal role in the development and progression of atherosclerosis. Recently, it was reported that monocytes can develop a long-lasting immunological memory after stimulation with various microorganisms, which has been termed 'trained innate immunity'. This memory is induced by epigenetic reprogramming. Here the investigators hypothesize that monocytes of patients with elevated LDL cholesterol levels show epigenetic (...) Effect of Statins on Trained Immunity Effect of Statins on Trained Immunity - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect of Statins on Trained Immunity The safety and scientific validity

2016 Clinical Trials

173. Combined Training on Body Composition of Postmenopausal Women Undergoing Treatment for Breast Cancer

Completion Date : June 2016 Resource links provided by the National Library of Medicine related topics: related topics: Arms and Interventions Go to Arm Intervention/treatment No Intervention: Group Control with breast cancer and without breast cancer Stretching exercises, lasting 40 minutes each session, 2 times a week for nine months Experimental: Combined Training with breast cancer and without breast cancer Combined Training: 36 weeks duration, 3 times a week on nonconsecutive days. The combined (...) Combined Training on Body Composition of Postmenopausal Women Undergoing Treatment for Breast Cancer Combined Training on Body Composition of Postmenopausal Women Undergoing Treatment for Breast Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2016 Clinical Trials

174. Telemedicine Strategy With Home Treatment Save Resources

Telemedicine Strategy With Home Treatment Save Resources Telemedicine Strategy With Home Treatment Save Resources - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Telemedicine Strategy With Home Treatment (...) Save Resources The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02214017 Recruitment Status : Completed First Posted : August 12, 2014 Results First Posted : November 19, 2018 Last Update Posted : November 19, 2018 Sponsor: Kolding Sygehus Information provided by (Responsible Party): Ole Winther

2014 Clinical Trials

175. A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol

A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study (...) of Evacetrapib (LY2484595) in Participants With High Cholesterol (ACCENTUATE) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02227784 Recruitment Status : Terminated (Study termination due to program termination.) First Posted : August 28, 2014 Results First Posted : March 22, 2018 Last Update Posted : March

2014 Clinical Trials

176. Effect of Rosuvastatin on Function of High Density Lipoprotein Cholesterol in Type 2 Diabetes

for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 50 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Effect of Rosuvastatin on Function of High Density Lipoprotein Cholesterol in Patients With Type 2 Diabetes Study Start Date : October 2014 Actual Primary Completion Date : December 2015 Actual Study Completion Date : May 2016 Resource links provided by the National Library of Medicine (...) expression of monocyte chemotactic protein-1 (MCP-1) Secondary Outcome Measures : Non-HDL-cholesterol = total cholesterol - HDL-C [ Time Frame: 12 weeks ] Patients with LDL-C < 70 mg/dl and HDL > 40 mg/dl in men; > 50 in women [ Time Frame: 12 weeks ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about

2014 Clinical Trials

177. Effect of an Inhibitor of Cholesterol Absorption on Vitamin D Levels

Effect of an Inhibitor of Cholesterol Absorption on Vitamin D Levels Effect of an Inhibitor of Cholesterol Absorption on Vitamin D Levels - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect (...) of an Inhibitor of Cholesterol Absorption on Vitamin D Levels The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02234544 Recruitment Status : Completed First Posted : September 9, 2014 Last Update Posted : April 9, 2015 Sponsor: Federal University of Rio Grande do Sul Information provided by (Responsible Party

2014 Clinical Trials

178. Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol

Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol (PFB) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02169245 Recruitment Status : Completed First Posted : June 23, 2014 Last Update Posted : February 5, 2016 Sponsor: Purdue University Collaborator

2014 Clinical Trials

179. A Study of Evacetrapib in Participants With Abnormal Cholesterol

A Study of Evacetrapib in Participants With Abnormal Cholesterol A Study of Evacetrapib in Participants With Abnormal Cholesterol - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study of Evacetrapib (...) in Participants With Abnormal Cholesterol The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02168803 Recruitment Status : Completed First Posted : June 20, 2014 Results First Posted : October 3, 2018 Last Update Posted : October 3, 2018 Sponsor: Eli Lilly and Company Information provided by (Responsible Party

2014 Clinical Trials

180. A Trial to Evaluate the Efficacy of AB-Life Probiotic Product on LDL-Cholesterol Reduction in Moderate Hypercholesterolemia

[ Time Frame: 12 weeks ] Fasting blood FGF-19 concentration [ Time Frame: 12 weeks ] Fasting blood LDLox concentration [ Time Frame: 12 weeks ] Fasting blood fibrinogen concentration [ Time Frame: 12 weeks ] Fasting blood biliary acids concentrations [ Time Frame: 12 weeks ] Fecal concentrations of neutral sterol including cholesterol and its secondary metabolites [ Time Frame: 12 weeks ] Fecal concentrations of phytosterols [ Time Frame: 12 weeks ] Fecal concentrations of volatil fatty acids [ Time (...) -CHOLESTEROL REDUCTION IN THE MODERATE HYPERCHOLESTEROLEMIA Study Start Date : September 2014 Actual Primary Completion Date : July 2015 Actual Study Completion Date : July 2015 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: AB-Life 1 capsule of AB-Life daily during 12 weeks consumed immediately before, after or during the breakfast. The daily dose corresponds to the intake of 1.8E+10 CFU. According

2014 Clinical Trials

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