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121. ESC/ESH Management of Arterial Hypertension

Electrocardiogram eGFR Estimated glomerular filtration rate ELSA European Lacidipine Study on Atherosclerosis ENaC Epithelial sodium channel ESC European Society of Cardiology ESH European Society of Hypertension FEVER Felodipine Event Reduction HAS-BLED Hypertension, Abnormal renal/liver function (1 point each), Stroke, Bleeding history or predisposition, Labile INR, Elderly (>65), Drugs/alcohol concomitantly (1 point each) HbA1c Haemoglobin A1c HBPM Home blood pressure monitoring HDL-C HDL cholesterol HELLP (...) Rosuvastatin LDH Lactate dehydrogenase LDL-C LDL cholesterol LEAD Lower extremity artery disease LIFE Losartan Intervention For Endpoint reduction in hypertension LV Left ventricular LVH Left ventricular hypertrophy MAP Mean arterial pressure MI Myocardial infarction MR Magnetic resonance MRA Mineralocorticoid receptor antagonist MRI Magnetic resonance imaging MUCH Masked uncontrolled hypertension NORDIL Nordic Diltiazem NS Non-significant NT-proBNP N-terminal pro-B natriuretic peptide o.d. Omni die (every

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2018 European Society of Cardiology

122. ESC/EACTS Guidelines on Myocardial Revascularization

with AF undergoing PCI PLATFORM Prospective LongitudinAl Trial of FFRct: Outcome and Resource Impacts, PLATO Study of Platelet Inhibition and Patient Outcomes pLVAD Percutaneous left ventricular assist device p.o. Per os (orally) POSEIDON Prevention of Contrast Renal Injury with Different Hydration Strategies PPI Proton pump inhibitor PRAGUE-18 Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction PRAMI Preventive Angioplasty in Acute Myocardial Infarction PRECISE-DAPT (...) in the European Heart Journal and the European Journal of Cardio-Thoracic Surgery . The task of developing clinical practice guidelines covers not only the integration of the most recent research, but also the creation of educational tools and implementation programmes for the recommendations. To implement the guidelines, condensed pocket guidelines, summary slides, booklets with essential messages, and an electronic version for digital applications (smartphones, etc.) are produced. These versions

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2018 European Society of Cardiology

123. Prepregnancy counseling

supplementation should be encouraged to reduce the risk of neural tube defects. (Fertil Steril 2019;111:32–42.2018 by the American College of Obstetricians and Gynecologists.) ACOGCOMMITTEEOPINION NUMBER762 CommitteeonGynecologic Practice AmericanSocietyfor ReproductiveMedicine This information is designed as an educational resource to aid clinicians in providing obstetric and gynecologic care, and use of this information is voluntary. This information should not be considered as inclusive of all proper (...) , address modi?able risk factors, and provide education about healthy pregnancy. All those planning to initiate a pregnancy should be counseled, including heterosexual, lesbian, gay, bisexual, transgender, queer, intersex, asexual, and gender nonconforming individuals. Counseling can begin with the following question: ‘‘Would you like to become pregnant in the next year?’’ Prepregnancy counseling is appropriate whether the reproductive-aged patient is currently using contraception

2019 Society for Assisted Reproductive Technology

124. Ethical Considerations for the Care of Patients With Obesity

, MA. This information is designed as an educational resource to aid clinicians in providing obstetric and gynecologic care, and use of this information is voluntary. This information should not be considered as inclusive of all proper treatments or methods of care or as a statement of the standard of care. It is not intended to substitute for the independent professional judgment of the treating clinician. Variations in practice may be warranted when, in the reasonable judgment of the treating (...) clinician, such course of action is indicated by the condition of the patient, limitations of available resources, or advances in knowledge or technology. The American College of Obstetricians and Gynecologists reviews its publications regularly; however, its publications may not reflect the most recent evidence. Any updates to this document can be found on or by calling the ACOG Resource Center. While ACOG makes every effort to present accurate and reliable information, this publication is provided

2019 American College of Obstetricians and Gynecologists

125. Prepregnancy Counseling

is designed as an educational resource to aid clinicians in providing obstetric and gynecologic care, and use of this information is voluntary. This information should not be considered as inclusive of all proper treatments or methods of care or as a statement of the standard of care. It is not intended to substitute for the independent professional judgment of the treating clinician. Variations in practice may be warranted when, in the reasonable judgment of the treating clinician, such course of action (...) is indicated by the condition of the patient, limitations of available resources, or advances in knowledge or technology. The American College of Obstetricians and Gynecologists reviews its publications regularly; however, its publications may not reflect the most recent evidence. Any updates to this document can be found on or by calling the ACOG Resource Center. While ACOG makes every effort to present accurate and reliable information, this publication is provided "as is" without any warranty

2019 American College of Obstetricians and Gynecologists

126. Recommendations for the Appropriate Structure, Communication, and Investigation of Tobacco Harm Reduction Claims: An Official ATS Policy Statement

of subjects by discussing the unique nature of risk inherent to harm reduction protocols. Promoting an understanding suf?cient for subjects to legitimately assume risk protects subjects from unforeseen or tragic consequences of participation through fairmethodsthatpromotejustoutcomes. d Harm reduction policies should state the perspective(s) from which they are derived, guard against inequitable allocation of resources, provide assurance of longitudinal surveillance, and inform the public of important (...) Volume 198 Number 8 | October 15 2018 normalize safe ride techniques such as designated drivers. Safer sex education aimed at teen students has reduced transmission of infectious disease, decreased teen pregnancy rates, and promoted safer sexual decision making among those engaged in sexual activity (16, 17). Alternatively, harm reduction strategies have also focused on minimizing the sequelae of exposures, without directly impacting behaviors. Examples include free or low-cost HIV testing

2019 American Thoracic Society

127. Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association

. Welty , Originally published 10 Dec 2018 Arteriosclerosis, Thrombosis, and Vascular Biology. 2018;39:e38–e81 Abstract One in 4 Americans >40 years of age takes a statin to reduce the risk of myocardial infarction, ischemic stroke, and other complications of atherosclerotic disease. The most effective statins produce a mean reduction in low-density lipoprotein cholesterol of 55% to 60% at the maximum dosage, and 6 of the 7 marketed statins are available in generic form, which makes them affordable (...) of these events is a priority. Overall, in patients for whom statin treatment is recommended by current guidelines, the benefits greatly outweigh the risks. The development and use of the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin) class of drugs, which, according to the prescribing information, reduce low-density lipoprotein cholesterol (LDL-C) on average by 55% to 60% at the maximal doses of the most potent statins, has had a major impact in reducing the incidence

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2019 American Gastroenterological Association Institute

128. Managing health and wellbeing in the workplace

. mission statement), (ii) connecting the vision to organisational values, strategy, practice and policy (i.e. build a health culture); (iii) gaining budget and resource commitment, (iv) educating and engaging senior management; (v) sharing the vision with employees, (vi) serving as a role model (‘walk the talk’), (vii) ensuring accountability and responsibility (for instance, KPI’s for senior management), (viii) rewarding success (for example, incentives, public recognition), (ix) adapting the program (...) HEALTH AND WELLBEING IN THE WORKPLACE | SAX INSTITUTE 9 blood pressure and cholesterol. There is sufficiently strong evidence to suggest that for every dollar invested in these programs (HRA+ program combinations) an annual return of $3.20 (ROI median $3.2; range $1.40 to $4.60) can be achieved. It is important, going forward, to raise the standards of quality and consistency of workplace wellness economic research which has to date been very variable. There is promising evidence that even higher

2018 Sax Institute Evidence Check

129. High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research

on Genetics and Genomics Show All... PubMed: Abstract Section: High-throughput, “next-generation” sequencing methods are now being broadly applied across all fields of biomedical research, including respiratory disease, critical care, and sleep medicine. Although there are numerous review articles and best practice guidelines related to sequencing methods and data analysis, there are fewer resources summarizing issues related to study design and interpretation, especially as applied to common, complex (...) the main conclusions of the workshop, specifically addressing the application of these methods in respiratory, critical care, and sleep medicine research. This workshop report may serve as a resource for our research community as well as for journal editors and reviewers of sequencing-based manuscript submissions in our research field. Keywords : ; ; ; ; ... Show All Contents Overview Workshop Agenda Principles of Study Design Study Designs and Phenotyping for Genetic Epidemiology Biobanks Health

2019 American Thoracic Society

130. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease

. Nutrition and Diet 18 3.2. Exercise and Physical Activity 21 4. Other Factors Affecting Cardiovascular Risk 24 4.1. Adults with Overweight and Obesity 24 4.2. Adults with Type 2 Diabetes Mellitus 26 4.3. Adults with High Blood Cholesterol 29 4.4. Adults with High Blood Pressure or Hypertension 35 4.5. Treatment of Tobacco Use 41 4.6. Aspirin Use 45 5. Cost and Value Considerations 47 6. Conclusion 48 Appendix 1. Search Criteria 50 Appendix 2. Author Relationships With Industry and Other Entities (...) by consideration of a sodium-glucose cotransporter 2 inhibitor or a glucagon-like peptide-1 receptor agonist. 7. All adults should be assessed at every healthcare visit for tobacco use, and those who use tobacco should be assisted and strongly advised to quit. 8. Aspirin should be used infrequently in the routine primary prevention of ASCVD because of lack of net benefit. 9. Statin therapy is first-line treatment for primary prevention of ASCVD in patients with elevated low- density lipoprotein cholesterol

2019 American Heart Association

131. Prostate Cancer

prostate cancer: results from the REDUCE study. Prostate Cancer Prostatic Dis, 2013. 16: 254. 33. James, N.D., et al. Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy. N Engl J Med, 2017. 377: 338. 34. YuPeng, L., et al. Cholesterol Levels in Blood and the Risk of Prostate Cancer: A Meta-analysis of 14 Prospective Studies. Cancer Epidemiol Biomarkers Prev, 2015. 24: 1086. 35. Vidal, A.C., et al. Obesity increases the risk for high-grade prostate cancer: results from

2019 European Association of Urology

132. AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm

and Drug Administration; GLP1 = glucagon-like peptide 1; HDL-C = high-density-lipoprotein cholesterol; HeFH = heterozygous familial hypercholesterolemia; LDL-C = low-density-lipoprotein cholesterol; LDL-P = low-density-lipoprotein particle; Look AHEAD = Look Action for Health in Diabetes; NPH = neutral protamine Hagedorn; OSA = obstructive sleep apnea; PCSK9 = proprotein convertase subtilisin-kexin type 9 serine protease; RCT = randomized controlled trial; SU = sulfonylurea; SGLT2 = sodium-glucose (...) algorithm panel. Lifestyle therapy begins with nutrition counseling and education. All patients should strive to attain and maintain an optimal weight through a primarily plant-based meal plan high in polyunsaturated and monounsaturated fatty acids, with limited intake of saturated fatty acids and avoidance of trans fats. Patients with overweight (body mass index [BMI] 25 to 29.9 kg/m 2 ) or obesity (BMI ≥30 kg/m 2 ; see Obesity section) should also restrict their caloric intake with the goal

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2019 American Association of Clinical Endocrinologists

133. Global Vascular Guidelines for patients with chronic limb-threatening ischemia

lipoprotein cholesterol LMICs Low- and middle-income countries LS Lumbar sympathectomy MACE Major adverse cardiovascular event MALE Major adverse limb event MRA Magnetic resonance angiography OPG Objective performance goal PAD Peripheral artery disease PBA Plain balloon angioplasty PFA Profunda femoris artery PLAN Patient risk estimation, limb staging, anatomic pattern of disease PROM Patient-reported outcomes measure PSV Peak systolic velocity PT Posterior tibial PVR Pulse volume recording RCT Randomized

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2019 Society for Vascular Surgery

134. Cardiac rehabilitation

concordance 20 9 Provision of information 21 9.1 Checklist for provision of information 21 9.2 Sources of further information 22 10 Implementing the guideline 25 10.1 Implementation strategy 25 10.2 Resource implications of key recommendations 25 10.3 Auditing current practice 25 11 The evidence base 26 11.1 Systematic literature review 26 11.2 Recommendations for research 26 11.3 Review and updating 27 12 Development of the guideline 28 12.1 Introduction 28 12.2 The guideline development group .28 12.3 (...) replaces the old four phase model with a 0–6 stage pathway including individualised assessment and care planning. 4 The standards describe a biopsychosocial approach to CR in which the overall aim is to equip the patient with the necessary knowledge and skills to enable them to successfully self manage their condition to live a longer, healthier, and more independent life. The approach is centred on patient education using health behaviour change techniques, which are patient centred and sensitive both

2017 SIGN

135. Pharmacological management of glycaemic control in people with type 2 diabetes

36 13.1 Implementation strategy 36 13.2 Resource implications of key recommendations 36 13.3 Auditing current practice 36 13.4 Health technology assessment advice for NHSScotland 36 14 The evidence base 37 14.1 Systematic literature review 37 14.2 Recommendations for research 38 15 Development of the guideline 39 15.1 Introduction 39 15.2 The guideline development group 39 15.3 Consultation and peer review 40 Abbreviations 42 Annex 1 45 References 46 Pharmacological management of glycaemic (...) (hyperglycaemia) is also one of the features of diabetes, along with raised blood pressure and cholesterol, which is associated with macrovascular complications (myocardial infarction, stroke, and peripheral arterial disease). The effects of glucose-lowering therapies on cardiovascular morbidity and mortality are therefore of major importance and not necessarily related to glucose lowering. Until 2010, the majority of clinical trials focused narrowly on glucose control (as assessed by HbA1c (glycated

2017 SIGN

136. Risk estimation and the prevention of cardiovascular disease

and the prevention of cardiovascular disease Contents9.4 Antiplatelet agents for people with hypertension 38 9.5 Antiplatelet agents for people with chronic kidney disease 38 10 Lipid lowering 39 10.1 The role of total and low-density lipoprotein cholesterol in cardiovascular disease 39 10.2 Measuring lipid levels 39 10.3 Lowering cholesterol to reduce cardiovascular risk 40 10.4 Statin therapy 40 10.5 Special considerations 48 10.6 Other lipid-lowering agents 51 10.7 Management of combined dyslipidaemia 55 11 (...) Implementing the guideline 74 14.1 Implementation strategy 74 14.2 Resource implications of key recommendations 74 14.3 Auditing current practice 74 14.4 Health technology assessment advice for NHSScotland 75 15 The evidence base 76 15.1 Systematic literature review 76 15.2 Recommendations for research 77 16 Development of the guideline 78 16.1 Introduction 78 16.2 The guideline development group 78 16.3 The steering group 79 16.4 Consultation and peer review 80 Abbreviations 82 Annexes 85 References 99

2017 SIGN

138. Personalised psychiatry

markers, and so further aspects around mental health could be added to these measurements. 10 Sramek J, Murphy M & Cutler N (2016). Sex differences in the psychopharmacological treatment of depression. Dialogues Clin Neurosci. 18(4), 446-457. The Academy of Medical Sciences 12 Early life and environmental measures A key message was the need to work more effectively across the social care and education system, particularly targeting children and adolescents, since these early stages of life can greatly (...) influence trajectories for mental health. Mental health questionnaires have been trialled across primary and secondary schools, providing a valuable source of data on risk factors. Integrating these measures as routine practice into the education and social care system will be essential for prevention and early intervention strategies. In addition, delegates described the need for more robust and extensive data collection on addiction (e.g. drugs or alcohol). The behavioural and lifestyle changes

2017 Academy of Medical Sciences

139. Mindfulness-based stress reduction (MBSR) for improving health, quality of life and social functioning in adults

Campbell Library comprises: • Systematic reviews (titles, protocols and reviews) • Policies and Guidelines Series • Methods Series Go to the library to download these resources, at: www.campbellcollaboration.org/library/ Better evidence for a better world Colophon Title Mindfulness-based stress reduction (MBSR) for improving health, quality of life and social functioning in adults: a systematic review and meta-analysis Authors Michael de Vibe, Norwegian Public Health Institute, Oslo, Norway Arild (...) University, USA Angela Higginson, Queensland University of Technology, Australia Disability Carlton J. Fong, Texas State University, USA Education Sarah Miller, Queen’s University Belfast, UK International Development Birte Snilstveit, 3ie, UK Hugh Waddington, 3ie, UK Social Welfare Brandy Maynard, Saint Louis University, USA Knowledge Translation and Implementation Aron Shlonsky, University of Melbourne, Australia Methods Therese Pigott, Loyola University, USA Ryan Williams, AIR, USA Managing Editor

2017 Campbell Collaboration

140. Cognitive Impairment - Part 1: Symptoms To Diagnosis

patients presenting with cognitive concerns and manage the majority of these patients and support their caregivers. TARGET POPULATION Older adults (65 years of age and greater) EXCLUSIONS Children Younger adults ( 53 years 4 Education >10 years 0 7-9 years 2 0-6 years 3 Sex Female 0 Male 1 Systolic Blood Pressure 140 mm Hg 2 Body Mass Index 30 kg/m 2 2 Total Cholesterol 6.5 mmol/L 2 Physical Activity Active 0 Inactive 1 TOTAL PATIENT HISTORY This should focus on how the illness developed and whether (...) there were any precipitating factors (e.g., vascular event). Background health information (e.g., medical problems, medications, alcohol and other recreational drug use, social history including years of education and presence of potential caregivers, family history) should be ascertained. 12 FAMILY/CAREGIVER INTERVIEW A separate history should be obtained from someone who knows the patient well to determine whether the cognitive and non-cognitive complaints represent a change from prior performance

2017 Toward Optimized Practice

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