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101. Bariatric surgery: an HTA report on the efficacy, safety and cost-effectiveness

the presence of (pre- )diabetes, hypertension, a low HDL-cholesterol, high triglycerides, and/or a high waist-circumference might indicate a higher associated risk, as is also the presence of non-alcoholic steato-hepatitis. Insulin resistance and metabolic syndrome are more prevalent in people with visceral adiposity. Obesity clearly does imply risks, may lead to physical and psychological symptoms, can cause functional limitation, the development of co- morbidities and complications, and cause psycho (...) characteristics, like e.g. the diabetes duration at moment of surgery. 39 Whether bariatric surgery is associated with a long-term reduction in complications from diabetes when compared with modern-day diabetes therapy is unknown. 39 The impact of surgery on serum lipids most often is a secondary study outcome. A pooled analysis of RCT data at 3 years showed a significant improvement (increase) in HDL cholesterol after surgery, but no statistically significant difference in serum triglycerides nor in total

2019 Belgian Health Care Knowledge Centre

102. Chronic kidney disease

, and providing the decrease in eGFR is 40% reduction in non-HDL cholesterol is not achieved. A renal specialist should be consulted if higher doses are required for patients with a eGFR 20%), increased length of hospital stay, and incomplete recovery of kidney function (many patients will be left with CKD). AKI and CKD are complex interconnected syndromes; CKD increases the risk of AKI and an episode of AKI increases the likelihood of subsequent development of CKD. Although AKI is common in hospitalised (...) for developing CKD after AKI is long-term and increases with increasing severity of AKI. 16 It is important to ensure appropriate follow-up and patient education. Patients should be monitored for the development or progression of CKD for at least two to three years after AKI, even if serum creatinine has returned to baseline. 2 A plan to carefully re-introduce or re-titrate necessary medicines that were withheld during the acute illness should be discussed with the patient together with the risk of recurrent

2018 WeMeReC

103. Menopause

Menopause CLINICAL PROFESSIONAL RESOURCE Menopause RCN guidance for nurses, midwives and health visitors Endorsed by This publication is supported by industryMENOPAUSE 2 This publication is due for review in November 2020. To provide feedback on its contents or on your experience of using the publication, please email publications.feedback@rcn.org.uk Acknowledgements This new publication is based on, and replaces, previous RCN publications – Women’s Health and the Menopause: RCN Guidance (...) 12 Screening 14 Hormone replacement therapy (HRT) 15 Prescribed alternatives to HRT 18 The therapeutic approach 19 Complementary approaches 19 6. Conclusion 24 References and further reading 25 Useful contacts and resources 26 ContentsMENOPAUSE 4 To provide support and advice to women it is important that all health care professionals understand the changes that women face at the time of their menopause and the issues related to improving health after menopause. Those working specifically

2018 Royal College of Nursing

104. Dietary patterns and cardiovascular disease outcomes

are based predominantly on single nutrients or foods. Recommendations include decreasing consumption of total fat, saturated fatty acids, cholesterol, salt and/or increasing consumption of fruit, vegetables, polyunsaturated fatty acids, monounsaturated fatty acids, fish, fibre and potassium. 4 Increasingly, literature has emerged that explores whole dietary patterns, rather than single nutrients or foods. Analysing food consumption in the form of dietary patterns offers a perspective different from (...) were determined to improve blood lipids, specifically total cholesterol and low-density cholesterol, while Low GI/GL was found to gain improvement in fat-free mass. Ten of the reviews for primary prevention included a meta-analysis, which compared a dietary pattern to another dietary approach. The comparator group varied across each of the meta-analysis and a detailed table of the comparators can be found in Appendix 7. The comparator diet was described as a ‘Western’ diet in n= 4 reviews, DASH

2018 Sax Institute Evidence Check

105. Multimorbidity: a priority for global health research

strategies for multimorbidity 60 5.3 Better models of healthcare for treating patients with multimorbidity 63 Acronyms 72 Glossary of terms 73 Annex 1: Project conduct and timeline 75 Annex 2: Membership of the working group, secretariat, and review group 76 Annex 3: Helpful resources 81 Annex 4: Clustering of conditions 82 Annex 5: Clustering of mental and physical health conditions 83 Annex 6: Sex as a determinant of multimorbidity 85 Annex 7: Ethnicity as a determinant of multimorbidity 87 Annex 8 (...) , and resource utilisation. 42,43 Many different weighted measures have been developed, including the Charlson Index, 44 the Chronic Disease Score, 45 the Adjusted Clinical Groups (ACG) System, 46 the Cumulative Illness Rating Scale (CIRS), 47 and the Functional Comorbidity Index (FCI). 48 A detailed description and appraisal of such measures is beyond the scope of this report, but each differ with respect to the study population and setting in which they have been most robustly validated (e.g. primary

2018 Academy of Medical Sciences

106. Accountable care organisations

a specified population for which providers are jointly accountable • Performance — determining target outcomes for the specified population, including resource use • Metrics and learning — developing and refining metrics to help determine whether outcomes are improving and to learn from these measurements and variations in results • Payment and incentives — restructuring payments and other incentives to align with the target outcomes, including details of risk-sharing arrangements • Coordinated delivery

2018 Sax Institute Evidence Check

107. The Patient Centred Medical Home: barriers and enablers to implementation

to specific populations 59 Additional enablers supporting the implementation of the PCMH 66 General 66 Education programs 67 Practice facilitation/ coaching 68 Learning collaboratives 69 Learning resources/ ‘toolkits’ 70 Performance measurement and feedback 70 Roles incorporated into primary care to support PCMH functions 71 Enablers for Indigenous populations 74 Gaps in the evidence 74 Discussion of findings 76 Applicability 78 Conclusion 79 References 80 Appendix 1: Literature selection process 88 (...) of care General strategies: Education programs Practice facilitation/coaching Learning communities/collaboratives Learning resources/’toolkits’ New/ enhanced roles: Medical practice assistant Community health workers Embedded pharmacists Integrated community specialists 3. Care coordination beyond the practice 3. Care coordination beyond the practice • Partnerships with community providers • Linkages with specialty and hospital care • Information sharing and continuity of care 4. Health information

2018 Sax Institute Evidence Check

108. Heart Disease and Stroke Statistics (Full text)

(smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure [BP], and glucose control) that contribute to cardiovascular health. The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, healthcare administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions. Cardiovascular disease (CVD) produces immense health and economic burdens in the United (...) Texas Health Resources Clinical Scholarship None None None None None None Amanda M. Perak Lurie Children’s None None None None None None None Wayne D. Rosamond Gillings School of Global Public Health, University of North Carolina, Department of Epidemiology None None None None None None None Gregory A. Roth University of Washington, Department of Medicine–Cardiology NHLBI ; Cardiovascular Medical Research and Education Foundation None None None None None None Uchechukwu K.A. Sampson New York

2019 American Heart Association PubMed

109. Terazosin

: Treatment Official Title: A Randomized, Double-blind, Placebo-Controlled, Crossover Study Assessing the Pharmacodynamic Effects of Dapoxetine Concomitantly Administered in Subjects Taking Terazosin Resource links 2011 18. Effects of Terazosin on Glycemic Control, Cholesterol, and Microalbuminuria in Patients with Non--Insulin-Dependent Diabetes Mellitus and Hypertension. 11862301 2002 02 25 2002 02 25 1536-3686 3 9 1996 Sep American journal of therapeutics Am J Ther Effects of Terazosin on Glycemic (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for terazosin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

110. Testosterone (Full text)

) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for testosterone The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you (...) has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page

2018 Trip Latest and Greatest PubMed

111. Statin

) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for statin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted (...) 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have

2018 Trip Latest and Greatest

112. Simvastatin

cholesterol HMGCoA 3-Hydroxy-3-Methylglutaryl Coenzyme A HR Hazard Ratio LDL-C Low-density lipoprotein cholesterol LLOQ Lower Limit of Quantification Lp(a) Lipoprotein (a) LXR Liver X Receptor MI Myocardial Infarction NCEP National Cholesterol Education Program PPAR Peroxysome proliferator activated receptor PK Pharmacokinetic PTY Patient Treatment Year(s) SVA Simvastatin acid SV Simvastatin T2DM Type 2 Diabetes Mellitus TG Triglycerides Tmax Time to peak concentration TSH Thyroid Stimulating Hormone 2013 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for simvastatin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

113. Lovastatin

" AND "Los Angeles" Search for studies: Study Record Detail Phase II Study of Cholesterol- and Cholestanol-Free Diet (...) , Lovastatin , and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years. Verified December 2003 by National Center for Research Resources (NCRR). Recruitment status was: Recruiting Sponsor: National Center for Research Resources (NCRR (...) lovastatin on serum lipids and C-reactive protein. 12876093 2003 07 23 2003 07 28 2016 10 17 1538-3598 290 4 2003 Jul 23 JAMA JAMA Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein. 502-10 To enhance the effectiveness of diet in lowering cholesterol, recommendations of the Adult Treatment Panel III of the National Cholesterol Education Program emphasize diets low (...) (SE) age of 59 (1) years and body mass index of 27.6 (0.5), recruited

2018 Trip Latest and Greatest

114. Menopause

or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for menopause The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence (...) has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page

2018 Trip Latest and Greatest

115. Rosuvastatin

, prospective, multicentre, double-blind, 3-arm, parallel group, active controlled study, randomised adult Chinese patients (...) (low-density lipoprotein-cholesterol (LDL-C) ≥130- <250 mg/dL statin-naive and ≥100- <160 mg/dL in statin treated) to receive rosuvastatin (5mg or 10mg) or atorvastatin 10mg. Patients not achieving National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III LDL-C targets in randomised phase were administered rosuvastatin 10mg and 20mg in the open-label phase (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for rosuvastatin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

116. Pravastatin

) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for pravastatin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you (...) been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page

2018 Trip Latest and Greatest

117. HIV

history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for hiv The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest (...) and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please

2018 Trip Latest and Greatest

118. Benazepril

) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for benazepril The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms (...) and/or care. Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side

2018 Trip Latest and Greatest

119. Atorvastatin

statin-naive and ≥100- <160 mg/dL in statin treated) to receive rosuvastatin (5mg or 10mg) or atorvastatin 10mg. Patients not achieving National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III LDL-C targets in randomised phase were administered rosuvastatin 10mg and 20mg in the open-label phase. RESULTS: A total of 414 patients (mean age: 59.5±9.51 years, 59.4% females, mean LDL-C: 4.242±0.676 mmol/L (rosuvastatin 5mg), 4.13±0.682 2017 8. A comparative effect of atorvastatin (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for atorvastatin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

120. Glimepiride

or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for glimepiride The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence (...) . Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side

2018 Trip Latest and Greatest

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