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361. DVT

) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for dvt The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted (...) and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please

2018 Trip Latest and Greatest

362. Benazepril

) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for benazepril The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms (...) and/or care. Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side

2018 Trip Latest and Greatest

363. Atorvastatin

statin-naive and ≥100- <160 mg/dL in statin treated) to receive rosuvastatin (5mg or 10mg) or atorvastatin 10mg. Patients not achieving National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III LDL-C targets in randomised phase were administered rosuvastatin 10mg and 20mg in the open-label phase. RESULTS: A total of 414 patients (mean age: 59.5±9.51 years, 59.4% females, mean LDL-C: 4.242±0.676 mmol/L (rosuvastatin 5mg), 4.13±0.682 2017 8. A comparative effect of atorvastatin (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for atorvastatin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

364. Lovastatin

" AND "Los Angeles" Search for studies: Study Record Detail Phase II Study of Cholesterol- and Cholestanol-Free Diet (...) , Lovastatin , and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years. Verified December 2003 by National Center for Research Resources (NCRR). Recruitment status was: Recruiting Sponsor: National Center for Research Resources (NCRR (...) of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com Top results for lovastatin 1. Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin , and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin , and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis - Full Text View - ClinicalTrials.gov A service of the U.S. National Institutes of Health Example: "Heart attack

2018 Trip Latest and Greatest

365. HIV

community, a peer is someone living with HIV who contributes (...) to positive health outcomes of other community members, but is not usually a health care professional with clinical training (1-3). Peers have made important contributions in HIV care, playing many roles and providing services such as education and social support (2, 4). Randomized controlled trials of peer programs to improve linkage, engagement and retention in HIV care have not shown significant differences compared to non-peer (...) history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for hiv The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest

2018 Trip Latest and Greatest

366. Gemfibrozil

This Collection Browse Statistics Are fish oil supplements as effective as gemfibrozil for decreasing elevated (...) triglycerides? View/ Open Date 2015-08 Format Metadata Abstract Are fish oil supplements as effective as gemfibrozil for decreasing elevated triglycerides? Evidence-Based Answer: The answer is unclear. In patients with hypertriglyceridemia, omega-3 fatty acid and fibric acid derivatives reduce triglyceride levels compared with baseline, but evidence is conflicting whether omega-3 fatty acid (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for gemfibrozil The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

367. Glimepiride

or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for glimepiride The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence (...) . Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side

2018 Trip Latest and Greatest

368. Terazosin

: Treatment Official Title: A Randomized, Double-blind, Placebo-Controlled, Crossover Study Assessing the Pharmacodynamic Effects of Dapoxetine Concomitantly Administered in Subjects Taking Terazosin Resource links 2011 18. Effects of Terazosin on Glycemic Control, Cholesterol, and Microalbuminuria in Patients with Non--Insulin-Dependent Diabetes Mellitus and Hypertension. 11862301 2002 02 25 2002 02 25 1536-3686 3 9 1996 Sep American journal of therapeutics Am J Ther Effects of Terazosin on Glycemic (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for terazosin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

369. Testosterone Full Text available with Trip Pro

) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for testosterone The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you (...) has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page

2018 Trip Latest and Greatest

370. Statin

-BASED ANSWER: Yes. Adding prescription-strength fish oil, or omega-3 fatty acids (OM3FA), to statin therapy is associated with an additional 20 percent to 30 percent reduction in triglyceride (TG 2018 7. Statins in primary cardiovascular prevention. Little benefit, documented harms and many uncertainties regarding long-term use Prescrire IN ENGLISH - Spotlight '' Statins in primary cardiovascular prevention. Little benefit, documented harms and many uncertainties regarding long-term use '', 1 July (...) ) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for statin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted

2018 Trip Latest and Greatest

371. Simvastatin

cholesterol HMGCoA 3-Hydroxy-3-Methylglutaryl Coenzyme A HR Hazard Ratio LDL-C Low-density lipoprotein cholesterol LLOQ Lower Limit of Quantification Lp(a) Lipoprotein (a) LXR Liver X Receptor MI Myocardial Infarction NCEP National Cholesterol Education Program PPAR Peroxysome proliferator activated receptor PK Pharmacokinetic PTY Patient Treatment Year(s) SVA Simvastatin acid SV Simvastatin T2DM Type 2 Diabetes Mellitus TG Triglycerides Tmax Time to peak concentration TSH Thyroid Stimulating Hormone 2013 (...) (...) with hypercholesterolemia and hypertriglyceridemia: a randomized, double-blind study. 175-86 10.2165/11533430-000000000-00000 To evaluate the efficacy and safety of fixed-dose combinations of rosuvastatin and fenofibric acid (rosuvastatin/fenofibric acid) compared with simvastatin in patients with high levels of low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG). Combination therapy with a statin and a fibrate is one of the treatment options to manage multiple lipid abnormalities in patients 2010 Follow

2018 Trip Latest and Greatest

372. Rosuvastatin

, prospective, multicentre, double-blind, 3-arm, parallel group, active controlled study, randomised adult Chinese patients (...) (low-density lipoprotein-cholesterol (LDL-C) ≥130- <250 mg/dL statin-naive and ≥100- <160 mg/dL in statin treated) to receive rosuvastatin (5mg or 10mg) or atorvastatin 10mg. Patients not achieving National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III LDL-C targets in randomised phase were administered rosuvastatin 10mg and 20mg in the open-label phase (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for rosuvastatin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

373. Pravastatin

the amount of cholesterol and other fatty substances in the blood. In addition, pravastatin is indicated 2012 11. Effects of pravastatin , phytosterols, and combination therapy on lipid profile in HIV-infected patients: an open-labelled, randomized cross-over study. 26148680 2015 07 07 2016 03 21 2017 02 20 1756-0500 8 2015 Jul 07 BMC research notes BMC Res Notes Effects of pravastatin , phytosterols, and combination therapy on lipid profile in HIV-infected patients: an open-labelled, randomized cross (...) ) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for pravastatin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you

2018 Trip Latest and Greatest

374. Menopause

or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for menopause The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence (...) has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search. As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page

2018 Trip Latest and Greatest

375. ESC/ESH Management of Arterial Hypertension Full Text available with Trip Pro

Pressure. The Guidelines were developed after careful consideration of the scientific and medical knowledge and the evidence available at the time of their dating. The task of developing ESC and ESH Guidelines also includes the creation of educational tools and implementation programmes for the recommendations including condensed pocket guideline versions, summary slides, booklets with essential messages, summary cards for non-specialists and an electronic version for digital applications (smartphones (...) influencing cardiovascular risk in patients with hypertension Demographic characteristics and laboratory parameters Sex (men >women) Age Smoking (current or past history) Total cholesterol and HDL-C Uric acid Diabetes Overweight or obesity Family history of premature CVD (men aged <55 years and women aged <65 years) Family or parental history of early-onset hypertension Early-onset menopause Sedentary lifestyle Psychosocial and socioeconomic factors Heart rate (resting values >80 beats/min) Asymptomatic

2018 European Society of Cardiology

376. International evidence-based guideline for the assessment and management of polycystic ovary syndrome (PCOS)

, with the opportunity for adaptation in relevant health systems as needed; ? providing a basis for improving patient outcomes; ? identifying knowledge gaps and promoting research and translation into practice and policy; ? co-developing resources to upskill health professionals and empower consumers, including a mobile app and online resources; and ? delivering an international translation program with in-depth evaluation. CONTENTS 8 Key principles Principles that underpinned the development and interpretation (...) professional’s clinical judgment or patient preference in diagnosis and treatment of individual patients. Ultimately, healthcare professionals must make their own clinical decisions on a case-by-case basis, using their clinical judgment, knowledge, and expertise, and taking into account the condition, circumstances, and perspectives of the individual patient, in consultation with that patient and/or the guardian or carer. The guideline partners make no warranty, express or implied, regarding the guideline

2018 European Society of Human Reproduction and Embryology

377. Dietary fats and cardiovascular disease

Linoleic acid LCMUFA Long-chain monounsaturated fatty acids LDL Low density lipoprotein MI Myocardial infarction MUFA Monounsaturated fat NHFA National Heart Foundation of Australia PUFA Polyunsaturated fat N3 fats Omega-3 fats N6 fats Omega-6 fats SFA Saturated fat TC Total cholesterol TFA Trans fatty acid 6 DIETARY FATS AND CARDIOVASCULAR DISEASE OUTCOMES | SAX INSTITUTE Executive summary Background Over the last six years the evidence in relation to saturated and polyunsaturated fat (PUFA) and heart (...) trials, only modest heterogeneity in study results remained after considering the test oil dose and the comparison oil type (I (2) = 27.5%). Palm oil was not different to trans-containing fats or animal fats. High oleic oils have been used to replace saturated fat or trans fats in 29 interventions 85 . LDL cholesterol was lowered by 10.9% when saturated fat was replaced (significant in 20 of 23 comparisons), and 9.2% when trans fatty acid was replaced (6 of 6 interventions). There was no significant

2018 Sax Institute Evidence Check

378. Dietary patterns and cardiovascular disease outcomes

are based predominantly on single nutrients or foods. Recommendations include decreasing consumption of total fat, saturated fatty acids, cholesterol, salt and/or increasing consumption of fruit, vegetables, polyunsaturated fatty acids, monounsaturated fatty acids, fish, fibre and potassium. 4 Increasingly, literature has emerged that explores whole dietary patterns, rather than single nutrients or foods. Analysing food consumption in the form of dietary patterns offers a perspective different from (...) . It may be reproduced in whole or in part for study training purposes subject to the inclusions of an acknowledgement of the source. It may not be reproduced for commercial usage or sale. Reproduction for purposes other than those indicated above requires written permission from the copyright owners. Enquiries regarding this report may be directed to the: Manager Knowledge Exchange Program Sax Institute www.saxinstitute.org.au knowledge.exchange@saxinstitute.org.au Phone: +61 2 91889500 Suggested

2018 Sax Institute Evidence Check

379. Menopause

women (NICE, 2017d). The National Osteoporoses Society provides detailed information on good sources of calcium (NOS, 2017). Facts about nutritional health – fats: • saturated fatty acids raise blood cholesterol levels • total fat consumed should be reduced, with no more than one third of calories coming from fat • saturated fats should be replaced with polyunsaturated fat and monounsaturated fat • cholesterol is mainly made in the liver from the saturated fats in food • polyunsaturated fatty acids (...) these risks factors, helping to support them in addressing those that are modifiable. Health care professionals, women and their partners can access posters, leaflets and information booklets that inform women about the breast screening programme from the information resources section of the NHSBSP website at: www.cancerscreening.nhs.uk/ breastscreen. A British Sign Language DVD and audio CD set, as well as information for women with learning difficulties, is also available. Bowel screening Men and women

2018 Royal College of Nursing

380. Do general health checks prolong lifespan?

and technology, and they were introduced as pharmaceuticals. Although novel drugs such as antihypertensive agents have "action to lower blood pressure”, the effect of prolonging the life span has not been proven by RCT except for a case of serious hypertension. Therefore, if RCT proved that a certain disease such as heart disease or stroke is reduced by the substance, it is accepted as a medicine. Cholesterol lowering agents and hypoglycemic agents are the other examples. Moreover, deregulation was made (...) -The Informed Prescriber Translated from the Editorial in Med Check-TIP (in Japanese) Jan 018 ; 18 (75) market in Japan. Development of some cholesterol- lowering agents was discontinued before approval. The hypoglycemic agents approved after 2000 do not reduce cardiovascular disease. Hence in the United States, a compromise was made to approve a product which at least showed non-inferiority to a placebo as a new valuable product. However, it may be very difficult to apply this method to any medicine. Hence

2018 Med Check - The Informed Prescriber

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