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321. Guidelines on Diabetes, Pre-Diabetes and Cardiovascular Diseases developed in collaboration with the EASD Full Text available with Trip Pro

are essential to assess, diagnostic/therapeutic processes, use of resources and adherence to Guidelines. These registries aim at providing a better understanding of medical practice in Europe and around the world, based on data collected during routine clinical practice. The guidelines are developed together with derivative educational material addressing the cultural and professional needs for cardiologists and allied professionals. Collecting high-quality observational data, at appropriate time interval (...) by the CPG for publication in the European Heart Journal. The Guidelines were developed after careful consideration of the scientific and medical knowledge and the evidence available at the time of their dating. The task of developing ESC Guidelines also includes the creation of educational tools and implementation programmes for the recommendations including condensed pocket guideline versions, summary slides, booklets with essential messages, summary cards for non-specialists and an electronic version

2019 European Society of Cardiology

322. ASGE guideline on screening and surveillance of Barrett’s esophagus

preferences, resource utilization, and cost-effectiveness. (Gastrointest Endosc 2019;89:1075-105.) Guidelines for appropriate use of endoscopy are based on a critical review of the available data and expert consensusat the time the guidelines were drafted.Further controlled clinical studies may be needed to clarify aspects of this guideline. This guideline may be revised as necessary to account for changes in technology, new data,orotheraspects ofclinicalpractice.Therecommen- dations in this document were (...) of the patient’sconditionandavailablecoursesofaction.There- fore, clinical considerations may lead an endoscopist to takeacourseofactionthatvariesfromtheseguidelines. INTRODUCTION Bile duct stones (choledocholithiasis) most frequently result from the migration of gallstones from the gall- bladder into the biliary tree. Gallstones are the conse- quence of cholesterol supersaturation in bile, inadequate bile salt levels or function, and diminished contractilityof thebiliary epitheliumbecauseofthemulti- factorial effects of diet, hormones, and genetic

2020 American Society for Gastrointestinal Endoscopy

323. Clinical Practice Guideline on the Management of Rotator Cuff Injuries

of Orthopaedic Surgeons, and articles published in AAOS Now. Selected clinical practice guidelines are disseminated by webinar, AAOS Online Learning, the Orthopaedic Video Theater (OVT), Media Briefings, and by distributing them at relevant Continuing Medical Education (CME) courses and at the AAOS Resource Center. 24 View background material via the RC CPG eAppendix 1 View data summaries via the RC CPG eAppendix 2 STUDY ATTRITION FLOWCHART 9464 abstracts reviewed. Primary search performed on June 26 th (...) research. This guideline is intended to be used by all qualified and appropriately trained physicians and surgeons involved in the management of rotator cuff tears. It is also intended to serve as an information resource for decision makers and developers of practice guidelines and recommendations. GOALS AND RATIONALE The purpose of this clinical practice guideline is to help improve treatment based on the current best evidence. Current evidence-based medicine (EBM) standards demand that physicians use

2020 American Academy of Orthopaedic Surgeons

324. Recognition and Initial Management of Fulminant Myocarditis: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

-directed medical care. Despite the increasing availability of circulatory support, orthotopic heart transplantation, and disease-specific treatments, patients with FM experience significant morbidity and mortality as a result of a delay in diagnosis and initiation of circulatory support and lack of appropriately trained specialists to manage the condition. This scientific statement outlines the resources necessary to manage the spectrum of FM, including extracorporeal life support, percutaneous (...) and durable ventricular assist devices, transplantation capabilities, and specialists in advanced heart failure, cardiothoracic surgery, cardiac pathology, immunology, and infectious disease. Education of frontline providers who are most likely to encounter FM first is essential to increase timely access to appropriately resourced facilities, to prevent multiorgan system failure, and to tailor disease-specific therapy as early as possible in the disease process. Fulminant: adjective ful··mi··nant | coming

2020 American Heart Association

325. 2020-2023 Value Assessment Framework

deductibles or otherwise reduce health care benefits for employees; for example, state governments might need to consider reducing next year’s education budget to find the funds to keep a Medicaid program afloat. In addition, for provider groups that bear financial risk, budget impact analyses inform very real short-term decisions about how to allocate resources to maximize the quality of health care within a given budget. A rapid increase in costs resulting from the significant budget impact of a new (...) or conditions that people experience and that affect the quantity or quality of life (e.g., change in pain, quality of life, length of life) are given greater weight than intermediate outcomes (e.g., change in cholesterol). Patient-important outcomes are health outcomes that are central to ICER’s judgements of benefit and harm. When appropriate, ICER also looks for evidence on non-clinical outcomes such as resource utilization or measures of societal benefit. • Timing: The minimum duration of study follow

2020 California Technology Assessment Forum

326. Productive healthy ageing: interventions for quality of life

for Productive Healthy Ageing 5 changing them, if appropriate) or by encouraging older people to increase their physical activity, reduce alcohol intake, maintain a healthy weight and balanced diet. The Centre for Pharmacy Postgraduate Education (CPPE), funded by Health Education England (HEE), provides a range of e-learning resources on topics such as Dementia and Older people. Pharmacy staff may want to use these learning materials to better support older people to live healthier lives to support (...) the staff can easily be seen. ? An assessment could be made on whether the pharmacy environment has appropriate lighting. Communication with people diagnosed with dementia and their carers 9 ? Training staff in how best to communicate with people with dementia and their carers is encouraged for all patient-facing staff. Health Education England (HEE) provides Tier 1 dementia awareness training and the Dementia Core Skills Education and Training Framework. ? Improves the environment for those with early

2019 Public Health England

327. Delivering novel therapies in the 21st century

at the point of a revolution in technologies. We have never been better placed for manipulation of cell phenotype at genotypic level.” Dr Tony Wood, GlaxoSmithKlineDelivering novel therapies in the 21st century – Conference report 7 The landscape for new biologics formats Dr Jane Osbourn of MedImmune discussed engineering antibodies to treat diabetes, optimising antibodies using machine learning, and functional screening of antibodies to identify new biologics targets. When first developed, biologics (...) antibody-drug conjugates, protein scaffolds and peptide fusions that combine functionality. These enable specificity to the drug target and bring benefits to particular disease settings. CASE STUDY 1 Antibody-peptide bispecific fusion A new antibody-peptide bispecific fusion combines different functionalities in one molecule. The monoclonal antibody a-PCSK9 lowers low density lipoprotein (so-called ‘bad’ cholesterol) in patients with cardiovascular disease. When bound to the peptide GLP-1R, which

2019 Academy of Medical Sciences

328. Population-level strategies to support healthy weight

for Health Transformation, Deakin University. October 2019 © Sax Institute 2019 This work is copyright. It may be reproduced in whole or in part for study training purposes subject to the inclusions of an acknowledgement of the source. It may not be reproduced for commercial usage or sale. Reproduction for purposes other than those indicated above requires written permission from the copyright owners. Enquiries regarding this report may be directed to the: Principal Analyst Knowledge Exchange Program Sax (...) , the greater the degree of individual agency required for an intervention to be effective, the more likely it is that the intervention will preferentially benefit people with a higher POPULATION-LEVEL STRATEGIES TO SUPPORT HEALTHY WEIGHT | SAX INSTITUTE 7 socioeconomic position compared with those with more limited social and economic resources. Accordingly, interventions focused on education and behaviour change are likely to have a negative overall impact on equity. In contrast, interventions that change

2019 Sax Institute Evidence Check

329. Addressing the social and commercial determinants of healthy weight

was prepared by: Sharon Friel and Sharni Goldman. October 2019 © Sax Institute 2019 This work is copyright. It may be reproduced in whole or in part for study training purposes subject to the inclusions of an acknowledgement of the source. It may not be reproduced for commercial usage or sale. Reproduction for purposes other than those indicated above requires written permission from the copyright owners. Enquiries regarding this report may be directed to the: Principal Analyst Knowledge Exchange Program (...) are developed. There was very little review level evidence examining these factors in relation to obesity/healthy eating/physical activity. The one review article found that acculturation into Australian society is associated with weight gain among migrants. The early years of life set a critical foundation for peoples’ entire life course - influencing basic learning, school success, economic participation, and social citizenry. Each of these provides skills and resources that influence dietary behaviour

2019 Sax Institute Evidence Check

330. Community Health Workers for Patients with Chronic Disease

support specialist for at least 2,000 hours between January 1, 2008, and June 30, 2021 (OHA, n.d.). To maintain certification status, all CHWs must complete 20 hours of approved continuing education plus one and half to three hours of an oral health training during every three-year renewal period (OAR 410-180-0325). Evidence Review Scott et al., 2018 This is a fair-quality meta-review that aggregates systematic reviews of CHW interventions published between 2005 and 2017. The review was prepared (...) ; training is shorter than that of a professional worker (i.e., training does not form part of a tertiary education certificate). • Is recognized (or can be identified) as a member of the community in which he or she works, defined by but not limited to, geographic location, Two studies in patients with diabetes found statistically significant improvements in HbA1c (range -0.5% to -2%) with CHW interventions; two studies found no difference in HbA1c Among three studies examining hypertension outcomes

2019 Oregon Health Evidence Review Commission

331. Palliative Care for Adults

Documents 11 Definitions 11 Annotations 12–45 Quality Improvement Support 46–56 Aims and Measures 47–48 Implementation Recommendations 49 Implementation Tools and Resources 50 Implementation Tools and Resources Tables 51–56 Assessment Tools 51 Physician Education Resources (Fast Facts) 51–52 General Tools and Resources 52–56 Supporting Evidence 57–76 References 58–63 Appendices 64–76 Appendix A: Literature Search Terms 64–65 Appendix B: How to Discuss Serious Illness 66–68 Appendix C: Signs and Symptoms (...) care to their patients in some manner. Indeed, there is a presumption that providers will all be able to provide a level of primary palliative care for symptoms commonly encountered in their respective practices. There is, however, growing recognition that primary care providers may need more education and training to recognize and evaluate other forms of distress and suffering in patients with serious illness. (Quill, 2013) Educational programs have been developed in recent years to assist

2020 Institute for Clinical Systems Improvement

332. Heart Disease and Stroke Statistics—2020 Update Full Text available with Trip Pro

, Inc. PMID: Originally published January 29, 2020 Keywords Subjects Title Title Title Title Circulation AHA Journals Journal Information Subjects Features Resources & Education For Authors & Reviewers National Center 7272 Greenville Ave. Dallas, TX 75231 Customer Service 1-800-AHA-USA-1 1-800-242-8721 ABOUT US OUR SITES TAKE ACTION ONLINE COMMUNITIES Follow Us: © American Heart Association, Inc. All rights reserved. Unauthorized use prohibited. The American Heart Association is qualified 501(c)(3 (...) , annually reports on the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical

2020 American Heart Association

333. KDOQI Clinical Practice Guidelines for Nutrition in CKD

- Oral, Enteral, and Parental Nutrition ……………………… ……………………………….. 103 4.2 Nutrition Supplementation - Dialysate………………………………………..…….…… 115 4.3 Long Chain Omega-3 Polyunsaturated Fatty Acids ………………………… 119 Guideline 5: Micronutrients.……………………………………………………….…………. 128 5.0 General Guidance ……………………………………………………………………….. 128 5.1 Folic acid (with and without other B Vitamins) ……..…………………………………… 132 5.2 Vitamin C ………………………………………………………………………………… 137 5.3 Vitamin D ………………………………………………………………………………… 142 5.4 Vitamin E (...) LBM Lean body mass LDL-C Low-density lipoprotein cholesterol LPD Low protein diet MAMC Mid-arm muscle circumference MF-BIA Multi-frequency-bio-electrical impedance analysis MGP Matrix Gla protein MHD Maintenance hemodialysis MHDE Maintenance Hemodialysis Equation MIS Malnutrition Inflammation Score MNA Mini-nutrition assessment MNA-SF Mini-Nutrition Assessment-Short Form MST Malnutrition Screening Tool MUST Malnutrition Universal Screening Tool NEAAs Non-essential amino acids NEAP Net endogenous

2020 National Kidney Foundation

334. Treatment of Patients with Schizophrenia

Balancing of Potential Benefits and Harms in Rating the Strength of the Guideline Statement3 Review of Available Guidelines from Other Organizations 1 Quality Measurement Considerations 1 Statement 23: Social Skills Training 1 Implementation 2 Balancing of Potential Benefits and Harms in Rating the Strength of the Guideline Statement2 Review of Available Guidelines from Other Organizations 3 Quality Measurement Considerations 3 Statement 24: Supportive Psychotherapy 3 Implementation 3 Balancing (...) Services 6 Statement 19: Assertive Community Treatment 3 Statement 20: Family Interventions 3 Statement 21: Self-management Skills and Recovery-focused Interventions 3 Statement 22: Cognitive Remediation 3 Statement 23: Social Skills Training 3 Statement 24: Supportive Psychotherapy 2 Appendix D. Strength of Evidence 3 Pharmacological Treatment 4 Assertive Community Treatment 34 Cognitive-behavioral Therapy 37 Cognitive Remediation 43 Family Interventions 45 Intensive Case Management 51 Illness

2020 American Psychiatric Association

335. Management of Chronic Kidney Disease

dosing • Promote lifestyle modifications o Diet, with special attention to sodium, potassium and phosphorus intake o Regular exercise o A healthy body weight o Immunizations o Tobacco cessation Resources Patient education resources are available at the National Kidney Foundation Website ( For links to recommended patient education materials, visit the University of Michigan Clinical Care Guidelines website Table 15. Drug-Induced Nephrotoxicity: Prevention Strategies, Patient Risk Factors (...) Management of Chronic Kidney Disease 1 UMHS Chronic Kidney Disease Guideline, July 2019 Quality Department Guidelines for Clinical Care Ambulatory Chronic Kidney Disease Guideline Team Team Leader Jennifer Reilly Lukela, MD General Medicine Team Members R. Van Harrison, PhD Medical Education Masahito Jimbo, MD Family Medicine Ahmad Mahallati, MD Nephrology Rajiv Saran, MBBS Nephrology Annie Z. Sy, PharmD Quality Management Program Initial Release: November, 2013 Interim/Minor Revision: March

2020 University of Michigan Health System

336. Telehealth and the use of video conferences: A Rapid Review

disease. Nor were there any reviews that focused on appointment attendance as an outcome measure. Figure 1. PRISMA flowchart of included studies Skype video conferencing 2 One review 2 looked specifically at the use of Skype, a low-cost or no-cost video conferencing tool in healthcare settings. They found that the use of Skype was most prevalent in the management of chronic diseases such as cardiovascular diseases and diabetes, followed by educational and speech and language pathology applications (...) significant reductions in HbA1c and LDL-cholesterol. These results are comparable to patient results from face-to-face visits with clinical pharmacists. There were no significant changes in the number of patients attaining their HbA1c or LDL- cholesterol goals after video conference intervention. 8 Paediatrics Patient satisfaction has been reported to be high for paediatric video conferencing, with reports of cost and time savings for patients. Patient comfort with the consultation was reported in 77

2019 Monash Health Evidence Reviews

337. Kaiser Permanente National Adult Blood Pressure Clinician Guide

), number of medication copays, and inconvenience. • Explore and help overcome barriers to medication adherence and monitoring. Collaborate with patients, families, caregivers, and the care team to problem solve and implement solutions. • Address depression and anxiety issues to maximize patient adherence. See KP National Depression Guideline at: • Educate patients about their goal BP because patients who are knowledgeable about (...) , typically found in 12 oz of regular beer (approximately 5% alcohol), 5 oz of wine (approximately 12% alcohol), and 1.5 oz of distilled spirits (approximately 40% alcohol). } To further promote vascular health, follow KP Guidelines to treat cholesterol and diabetes mellitus, recommend aspirin use, and promote tobacco cessation. } Encourage adherence to medications and monitoring. Help overcome barriers. • Once-daily and combination pills can help minimize pill burden (number of daily pills needed

2019 Kaiser Permanente National Guideline Program

338. Management of Type 2 Diabetes Mellitus

, social and emotional resources and prevent long and short-term effects from diabetes. Diabetes self-management education (DSME) is the essential first step in becoming an effective self-manager. DSME is designed to help patients make informed decisions and evaluate the costs and benefits of those choices. In addition to DSME, patients with diabetes also need on-going self-management support (DSMS) in order to sustain improvements gained during DSME. Table 3 summarizes self-management topics (...) that clinicians should address at each visit and annually. DSME has evolved from didactic programs based on information-transfer and compliance or adherence as outcomes, to more patient-centered, empowerment based approaches. Recent findings related to DSME include: • Diabetes self-management education is effective for improving psychosocial and health outcomes (including HbA1c) and for reducing costs. • Traditional knowledge based DSME is essential but not sufficient for sustained behavior change. People

2020 University of Michigan Health System

339. Acute Kidney Injury (AKI)

descriptives (e.g. ‘pre-renal’ and ‘renal / intrinsic’) to pathophysiological ones (‘functional change’ and ‘kidney damage’, respectively) [34]. Given the momentum of current training and educational endeavours, particularly across the UK, a change in nomenclature, we feel, would be counterproductive at this stage. Paediatric considerations (to be read in conjunction with adult guidance, above) Clinical Assessment; History, Examination Rationale As discussed above in relation to adult disease, the early (...) in the delivery of this care as well as relevant patient groups. It excludes the neonatal population and adults at risk of contrast nephropathy, for whom joint guidance already exists [1]. In the context of UK practice, our document joins Clinical Guidelines from the National Institute for Health and Care Excellence (NICE CG 169) [2] and the extensive resources of the Think Kidneys programme ( . The view of the guideline development group was that the present work should

2019 Renal Association

340. National Adult Diabetes Clinician Guide

with an abnormal monofilament test (i.e., at high-risk for lower limb complications), consider referral to or management by a podiatry population-based foot care program or equivalent. • For adults with diabetes, consider initiating annual foot screening examinations. SELF-MANAGEMENT Education • Initiate patient training in self-care behaviors to improve glucose control. Monitoring of Blood Glucose in Type 1 Diabetes • For adults with type 1 diabetes, advise self-monitoring of blood glucose (SMBG). CLINICAL (...) depending on baseline HbA1C, baseline BMI (> 30 vs. 9 lbs., a diagnosis of GDM or polycystic ovary syndrome (PCOS) ? hypertension (= 140/90 mmHg or on therapy for hypertension) ? high-density lipoprotein cholesterol (HDL-C) level 250 mg/dl (2.82 mmol/l), or both ? HbA1c = 5.7%, IGT, or IFG on previous testing ? other clinical conditions associated with insulin resistance (e.g., severe obesity [defined as BMI = 40 kp/m 2 ], acanthosis nigricans) CLINICAL PRACTICE GUIDELINES | NATL February 2019 BLOOD

2019 Kaiser Permanente National Guideline Program

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