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Cholesterol Education Resources

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181. Atherosclerotic Cardiovascular Disease in South Asians in the United States: Epidemiology, Risk Factors, and Treatments: A Scientific Statement From the American Heart Association

of the world’s population and are one of the fastest-growing ethnic groups in the United States. Although native South Asians share genetic and cultural risk factors with South Asians abroad, South Asians in the United States can differ in socioeconomic status, education, healthcare behaviors, attitudes, and health insurance, which can affect their risk and the treatment and outcomes of atherosclerotic cardiovascular disease (ASCVD). South Asians have higher proportional mortality rates from ASCVD compared (...) disease (ASCVD) risk in South Asians compared with other populations. Cardiovascular disease (CVD) and diabetes mellitus (DM) have also been shown to be more frequent among Fiji Indians. , Although people living in South Asian countries share genetic and cultural risk factors with South Asians living abroad, South Asians residing in the United States can differ in socioeconomic status, education, healthcare behaviors, attitudes, and health insurance, which can affect their risk and the treatment

2018 American Heart Association

182. Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

lipid traits; in 1 notable example, they found that loss-of-function variants in APOB were associated with decreased low-density lipoprotein cholesterol levels and triglyceride levels but also increased alanine and aspartate aminotransferase levels, consistent with hepatocyte injury. Notably, patients receiving the APOB -targeting medication mipomersen experience lower low-density lipoprotein cholesterol levels and, in some cases, elevated hepatic transaminases or other liver conditions (...) identified a number of associations, with the most intriguing finding being that methylation of a CpG site near the ABCG1 gene was correlated with decreased expression of the gene, a known regulator of macrophage cholesterol efflux and reverse cholesterol transport; increased triglycerides and decreased high-density lipoprotein cholesterol; and substantially increased risk of coronary artery disease. Transcriptomic analyses of peripheral blood mononuclear cells from patients with and without coronary

2018 American Heart Association

183. Health Literacy and Cardiovascular Disease: Fundamental Relevance to Primary and Secondary Prevention: A Scientific Statement From the American Heart Association

and the diverse perspectives of the experts on the writing group. The 10-member writing group for this statement is diverse in its demographic composition, disciplinary perspectives, and context expertise. It consists of 4 women, includes 2 underrepresented minorities, and comprises clinicians (internal medicine, cardiovascular physicians, and nurses) and clinician scientists engaged in health services research, epidemiology, health education, and behavioral health interventions. The committee is further (...) enhanced by individuals with expertise in social determinants of health (including health literacy) and cardiovascular health disparities affecting racial/ethnic minorities and rural populations and the development and evaluation of community-based interventions and strategies to promote health. Health Literacy: Definitions and Dimensions Measuring Literacy in the United States In 1992, the US Department of Education initiated the first population-based, in-person assessment of adult literacy

2018 American Heart Association

184. Promoting Risk Identification and Reduction of Cardiovascular Disease in Women Through Collaboration With Obstetricians and Gynecologists: A Presidential Advisory From the American Heart Association and the American College of Obstetricians and Gynecologi Full Text available with Trip Pro

, including standardized protocols and enhanced cardiac screening. Shared information can be used to assess risk, initiate interventions, and facilitate significant lifestyle changes. Care can be coordinated to minimize cardiovascular morbidity and mortality and to improve outcomes. By providing a platform for comprehensive well-woman care, primary prevention, and early intervention, providers of women’s health can provide patient education, empowerment, and motivation. Educational Resources Primary care (...) for cardiovascular risk factors. Hypercholesterolemia imparts the highest population-adjusted cardiovascular risk for women at 47%; benefits of statin therapy are similar for women and men. , The new Pooled Cohort Risk Equations, which are gender-specific and should be used for cholesterol management with lifestyle guidelines, are applicable to both genders. Given that 2 of 3 women in the United States are either obese or overweight, we must be cognizant of the adverse associations that increased weight has

2018 American Heart Association

185. Mobile Health Applications for Self-Management of Diabetes

Mobile Health Applications for Self-Management of Diabetes e Technical Brief Number 31 Mobile Health Applications for Self-Management of DiabetesTechnical Brief Number 31 Mobile Applications for Self-Management of Diabetes Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahrq.gov Contract Nos. 290-2012-0004-C and -290-2017-0000-3C Prepared by: Scientific Resource Center Portland, OR Investigators (...) and longer-term research studies could determine whether apps help people manage their diabetes and reduce complications. • Studies had methodological issues: they were short (2-12 months); inconsistent in reporting of randomization, allocation, masking, and drop-out analysis; and often used co-interventions that hindered interpretation of results. None of the included studies are considered to be high quality. iii This report is based on research conducted by the Scientific Resource Center under

2018 Effective Health Care Program (AHRQ)

187. Diet and the Gut

that are nutritionally deficient in one or more respects. It is vital, therefore, that whenever possible the medical practitioner should engage the services of a skilled nutritionist/dietitian to evaluate a given individual’s nutritional status, instruct the patient on new diet plans, and monitor progress. It is also incumbent on gastroenterologists to become educated on modern dietary practices as they relate to gastrointestinal health and disease. We hope that this guideline will become a valuable resource (...) those who suffer from gastrointestinal ailments—rightly perceive their diet as being a major determinant of such symptoms and seek guidance on optimal dietary regimens. Many medical practitioners, including gastroenterologists, are unfortunately often ill-prepared to deal with such issues. This is a reflection of the lack of education on the topic of diet and nutrition in many curricula. Dietary changes have the potential to alleviate symptoms, but they may also result in regimens

2018 World Gastroenterology Organisation

188. Routine Assessment and Promotion of Physical Activity in Healthcare Settings: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

feedback indicates higher likelihood of use if located in the vitals section as opposed to social history or other EHR sections. The organization has an internal Wiki web page that provides resources for the EVS implementation and patient resources for increasing PA. Also desirable is combining the EVS with clinical decision support system features to enable adequate risk stratification and provision of appropriate patient education material tailored to the patient’s clinical diagnosis and preferences (...) impact of regular PA on traditional cardiovascular risk factors explains a significant portion of its salutatory impact. These favorable effects on traditional risk factors include increasing high-density lipoprotein cholesterol, reducing body mass index, improving insulin sensitivity, and reducing blood pressure, which, although often modest, significantly reduce risk at the population level. However, a significant portion of the cardiovascular benefits of habitual PA are independent of its effects

2018 American Heart Association

190. Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks

medical reference and in conjunction with all other pertinent information, i.e., in the context of available resources and circumstances presented by individual patients. This report is made available to the public under the terms of a licensing agreement between the author and the Agency for Healthcare Research and Quality. This report may be used and reprinted without permission except those copyrighted materials that are clearly noted in the report. Further reproduction of those copyrighted (...) may increase is called the Tolerable Upper Intake Level (UL). The DRIs are for dietary intakes only (i.e., foods and dietary supplements) and are intended to cover the needs of almost all healthy persons. These values serve multiple purposes, including guidance for (a) health professionals for use in dietary counseling and for developing educational materials for consumers and patients, (b) scientists in designing and interpreting research, (c) ES-2 users of national nutrition monitoring, and (d

2018 Effective Health Care Program (AHRQ)

191. Neonatal jaundice

clinicians are responsible for: · Providing care within the context of locally available resources, expertise, and scope of practice · Supporting consumer rights and informed decision making, including the right to decline intervention or ongoing management · Advising consumers of their choices in an environment that is culturally appropriate and which enables comfortable and confidential discussion. This includes the use of interpreter services where necessary · Ensuring informed consent is obtained

2018 Queensland Health

192. Developing a National Pain Strategy for Canada

in preventing and managing chronic pain in primary and specialty care, which is where the rubber really hits the road for people living with or at risk for chronic pain. The Chronic Care Model’s six features – self-management support, decision support, delivery-system design, clinical information systems, health-system changes, and community resources – are used to frame this big picture. o Generally, we found evidence supporting the use of self-management programs, multidisciplinary and stepped care (...) , and clinical information systems to help manage chronic pain at the primary and secondary levels. We also found that embedding pain-management awareness into organizational structures may facilitate health-system changes. Finally, we found that citizen engagement can assist with the dissemination of information, process for developing interventions, and enhancing awareness and understanding. • Element 2 (Better prevention/education) – Reduce the emergence of chronic pain and its sequelae (including opioid

2017 McMaster Health Forum

193. CRACKCast E172 – Pediatric Gastrointestinal Disorders

is more commonly caused by cholestasis rather than biliary obstruction. Pigment gallstones are more common than cholesterol stones in children. Biliary tract disease is usually diagnosed with right upper quadrant ultrasound imaging; management strategies are similar to those for adults. Rosens in Perspective Gastrointestinal disorders are tough! Non-verbal children can present with virtually any set of symptomatology! It may be helpful to organize these varied gastrointestinal diseases by patient age (...) here at this slideshare resource: [11] Describe the “Rule of 2” for Meckel’s Diverticulum Meckel’s diverticulum traditionally follow so-called the rule of 2’s. The diverticulum is 2 cm wide, 2 cm long, and located within 2 feet of the ileocecal valve. Moreover, the condition occurs in 2% of the population, and only 2% of affected patients ever become symptomatic. Of symptomatic patients, 50% manifest symptoms by the age of 2 years, and most present by the age of 20 years. [12] What are 3 common

2018 CandiEM

194. The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis

therapy should be made by a consultant rheumatologist. Following national initiatives and guidance, patients and/or their carers should be actively involved in the decision making processes. (ii) Patients should be provided with education about their treatment to promote self-management (grade 1B, SOA 99%). A Cochrane review in 2002 demonstrated that education had a positive effect in terms of both patient reported outcome and objective measures of clinical response; however, the benefits were (...) not observed during a longer duration of follow-up [ ]. The Department of Health has estimated that the average cost of education and self-management is £125/person and would save costs of £244/person on average [ ]. Rheumatologists should therefore offer patients with IA the opportunity to discuss their condition and the risks and benefits of treatments both at diagnosis and throughout the course of their disease. Patients with IA should be offered verbal and written information to improve

2018 British Society for Rheumatology

195. Prostate Cancer

prostate cancer: results from the REDUCE study. Prostate Cancer Prostatic Dis, 2013. 16: 254. 33. James, N.D., et al. Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy. N Engl J Med, 2017. 377: 338. 34. YuPeng, L., et al. Cholesterol Levels in Blood and the Risk of Prostate Cancer: A Meta-analysis of 14 Prospective Studies. Cancer Epidemiol Biomarkers Prev, 2015. 24: 1086. 35. Vidal, A.C., et al. Obesity increases the risk for high-grade prostate cancer: results from

2018 European Association of Urology

196. Cardiovascular Health in Turner Syndrome: A Scientific Statement From the American Heart Association

years. The specific management of many cardiovascular conditions, both congenital and acquired, is the same as in the general population. For these conditions, established guidelines should be followed. The purpose here is to highlight the instances in which there are unique cardiovascular risks involved in TS and to provide guidance for their monitoring and management. Working Group In July 2016, the Turner Resource Network hosted an international meeting of experts to make recommendations (...) -specific z score of >3 should not participate in any competitive sports. Girls or women with TS who are ≥15 years of age with an ascending ASI >2.3 cm/m 2 should not participate in any competitive sports. Transition Transition is a process to optimize lifelong functioning and potential with high-quality, developmentally appropriate, and uninterrupted health care from adolescence to adulthood. To be successful, this process should attend to the medical, psychosocial, educational, and vocational needs

2018 American Heart Association

197. Stroke Prevention in Patients With Atrial Fibrillation: A Systematic Review Update

information, i.e., in the context of available resources and circumstances presented by individual patients. This report is made available to the public under the terms of a licensing agreement between the author and AHRQ. This report may be used and reprinted without permission except those copyrighted materials that are clearly noted in the report. Further reproduction of those copyrighted materials is prohibited without the express permission of copyright holders. PCORI, AHRQ, or U.S. Department

2018 Effective Health Care Program (AHRQ)

198. Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers

information, i.e., in the context of available resources and circumstances presented by individual patients. This report is made available to the public under the terms of a licensing agreement between the author and the Agency for Healthcare Research and Quality. This report may be used and reprinted without permission except those copyrighted materials that are clearly noted in the report. Further reproduction of those copyrighted materials is prohibited without the express permission of copyright (...) ’ exercise. 4-6 Thinking aloud is a method grounded in cognitive psychological and educational research whereby individuals talk aloud while performing a task. The method was intended to generate direct data on the ongoing thought processes of SCN leaders while reviewing the summaries (i.e., when reviewing a specific summary, how do they 6 see themselves using this information to inform decisions, and could they communicate this information to their colleagues and staff). This exercise covered critical

2018 Effective Health Care Program (AHRQ)

199. Weight Loss to Prevent Obesity-Related Morbidity and Mortality in Adults: Behavioral Interventions

for cardiovascular disease prevention in adults with and without common risk factors , ( ). The USPSTF recommends that clinicians screen for obesity in children 6 years or older and offer or refer them to a comprehensive, intensive behavioral intervention (B recommendation). Useful Resources The Community Preventive Services Task Force recommends multicomponent interventions that use technology-supported coaching or counseling to help adults lose weight and maintain weight loss. Other Considerations Research (...) Angeles); Maureen G. Phipps, MD, MPH (Brown University, Providence, Rhode Island); Michael Silverstein, MD, MPH (Boston University, Boston, Massachusetts); Melissa A. Simon, MD, MPH (Northwestern University, Evanston, Illinois); Chien-Wen Tseng, MD, MPH, MSEE (University of Hawaii, Honolulu, and Pacific Health Research and Education Institute, Honolulu, Hawaii); John B. Wong, MD (Tufts University, Medford, Massachusetts). Copyright and Source Information Conflict of Interest Disclosures: All authors

2018 U.S. Preventive Services Task Force

200. Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency

) to improve the positive predictive value of congenital adrenal hyperplasia screening. (1|⊕⊕○○) Technical remark: Laboratories utilizing liquid chromatography–tandem mass spectrometry should participate in an appropriate quality assurance program. Additionally, clinicians should realize that immunoassays lead to more false-positive results. Thus, if laboratory resources do not include liquid chromatography–tandem mass spectrometry, a cosyntropin stimulation test should be performed to confirm diagnosis (...) educating patients and their guardians and close contacts on adrenal crisis prevention and increasing the dose of glucocorticoid (but not mineralocorticoid) during intercurrent illness. (1|⊕⊕⊕○) 4.11 We recommend equipping every patient with congenital adrenal hyperplasia with a glucocorticoid injection kit for emergency use and providing education on parenteral self-administration (young adult and older) or lay administration (parent or guardian) of emergency glucocorticoids. (1|⊕⊕⊕○) Monitoring

2018 The Endocrine Society

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