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Cholesteatoma

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81. Parotid gland cholesteatoma in a 23-year-old male: Case report Full Text available with Trip Pro

Parotid gland cholesteatoma in a 23-year-old male: Case report Cholesteatoma is a pathological tissue that may extend into all parts of temporal bone and rarely, as this study highlights, beyond its structures. Nevertheless, the spread outside the mastoid tip into the soft tissues of the neck or parotid space is very rare. The case of 23-year-old male with right parotid mass is presented. The patient had history (2006, 2009, and 2012) of three tympanoplastics for recurrent right ear (...) cholesteatoma. The parotid tumor was revealed incidentally in magnetic resonance imaging in January 2016, but the imaging was inconclusive. After 6 months, the patient developed right-sided facial nerve palsy. The second look of the right ear was performed with simultaneous parotid surgery. The ear was healed and free of cholesteatoma, but the parotid mass resembled the cholesteatoma confirmed later on by histological examination. The tumor extended from stylomastoid foramen. This case was unusual

2017 SAGE Open Medical Case Reports

82. A Rare Case Report and Literature Review of External Auditory Canal Cholesteatoma with Circumferential Destruction of Canal Wall Exposing Facial Nerve Full Text available with Trip Pro

A Rare Case Report and Literature Review of External Auditory Canal Cholesteatoma with Circumferential Destruction of Canal Wall Exposing Facial Nerve External auditory canal cholesteatoma (EACC) is a rare condition with an estimated incidence of 1.2 per 1000 new otological patients. It is often mistaken with keratosis obturans. We discuss an extensive primary EACC with an aural polyp in a male which was managed by modified radical mastoidectomy.

2017 Case reports in otolaryngology

83. Clinical Characteristics and Treatment Outcomes for Patients With External Auditory Canal Cholesteatoma. (Abstract)

Clinical Characteristics and Treatment Outcomes for Patients With External Auditory Canal Cholesteatoma. We aimed to evaluate the clinical features and treatment outcomes for patients with idiopathic and secondary external auditory canal cholesteatoma (EACC), and to validate the treatment strategy from the perspective of hearing as well as etiology and staging.Retrospective case series.Tertiary referral center and affiliated hospitals.Fifty-eight patients with idiopathic EACC and 14 patients

2017 Otology and Neurotology

84. Risk Factors of Recurrence in Pediatric Congenital Cholesteatoma. (Abstract)

Risk Factors of Recurrence in Pediatric Congenital Cholesteatoma. To examine the risk factors of recurrence in pediatric congenital cholesteatoma.Retrospective chart review.University hospital.Sixty-seven patients having tympanic type of congenital cholesteatoma under 15-years old at surgery.Canal wall-up tympanomastoidectomy (n = 30) or transcanal atticotomy/tympanoplasty (n = 37) was performed depending on cholesteatoma extension, 16 of which were followed by second-look surgery. Preoperative (...) computed tomography (CT) before second-look surgery or follow-up CT was performed to detect residual recurrence 1 year after the surgery. Cholesteatoma found at the second surgery was also included in the recurrence. All patients had no recurrent cholesteatoma at the last follow-up (median, 61 mo after surgery).Possible predictive factors were compared between the groups.Residual cholesteatoma and retraction cholesteatoma occurred in 21 and 6%, respectively. There was no significant difference in age

2017 Otology and Neurotology

85. Cholesteatoma as a complication of Langerhans Cell Histiocytosis of the temporal bone: A nationwide cross-sectional analysis. (Abstract)

Cholesteatoma as a complication of Langerhans Cell Histiocytosis of the temporal bone: A nationwide cross-sectional analysis. To determine if patients with Langerhans Cell Histiocytosis (LCH) of the temporal bone have a higher risk of developing cholesteatoma.Review of literature and cross-sectional weighted analysis of patients under 19 with a diagnosis of LCH from the National Inpatient Sample (NIS) and Kids' Inpatient Database (KID) from 2000 to 2013. ICD-9 codes and demographics were (...) analyzed; pairwise comparisons and multivariate analyses were performed.Only seven cases of cholesteatoma after the treatment for LCH of the temporal bone have been documented in the literature. No significant association between cholesteatoma and LCH was seen (OR 0.747 [0.149-3.751]). Patients with LCH did have a higher incidence of chronic otitis media, chronic otitis externa, chronic sinusitis, hearing loss, and otitis media with effusion.Our results show that patients with Langerhans Cell

2017 International Journal of Pediatric Otorhinolaryngology

86. The Prevention of Recurrent Cholesteatoma in CWU Surgery: The Use of Titanium Sheeting. (Abstract)

The Prevention of Recurrent Cholesteatoma in CWU Surgery: The Use of Titanium Sheeting. Assessment of the outcomes of a technique of prevention of recurrent cholesteatoma in canal wall up (CWU) mastoidectomy, using titanium sheeting to repair the external auditory canal wall.Sixty four cholesteatoma cases were managed during a period from 2007 to 2015. The cases were unselected; the surgery was performed by the senior author. Cholesteatoma Patterns Were: Forty two attic, nine pars tensa, seven

2017 Otology and Neurotology

87. Increased risk of cholesteatoma among patients with allergic rhinitis: A nationwide investigation. (Abstract)

Increased risk of cholesteatoma among patients with allergic rhinitis: A nationwide investigation. No large population-based studies have reported on the risk of cholesteatoma developing after allergic rhinitis (AR). This study used a nationwide population-based claims database to investigate the hypothesis that AR may increase the risk of cholesteatoma.Retrospective cohort study.Data from Taiwan's Longitudinal Health Insurance Database were analyzed to compile the following: 1) 15,953 patients (...) newly diagnosed with AR between 1997 and 2000, and 2) a comparison cohort of 63,812 matched non-AR enrollees (with a ratio of 1 to 4). Each patient was followed for 10 years to identify cases in which cholesteatoma subsequently developed. The Kaplan-Meier method was used to determine the cholesteatoma-free survival rate, and the log-rank test was used to compare survival curves. Cox proportional hazard regressions were performed to compute adjusted hazard ratios (HRs).Among the 79,765 patients

2017 Laryngoscope

88. Mycology of chronic suppurative otitis media-cholesteatoma disease: An evaluative study. (Abstract)

Mycology of chronic suppurative otitis media-cholesteatoma disease: An evaluative study. To detect the prevalence of fungus in chronic suppurative otitis media-cholesteatoma disease and to evaluate its clinical significance.Prospective observational study conducted in a sample size of 46 patients at a tertiary care university teaching hospital.Forty six patients suffering from chronic suppurative otitis media-cholesteatoma disease were recruited in this prospective study. Data was duly recorded (...) . Cholesteatoma sample was procured at the time of mastoid surgery and microbiologically analysed for fungal infestation. Clinical correlation to fungus infestation of cholesteatoma was statistically analysed.Out of the recruited 46 patients, post-operatively cholesteatoma was seen in 40 cases only. Seventeen i.e. 42.5% of these cases had fungal colonization of cholesteatoma. Further a statistically significant correlation between persistent otorrhoea and fungal infestation of cholesteatoma was observed

2017 American Journal of Otolaryngology

89. Postoperative efficacy analysis of patients with facial nerve palsy associated with cholesteatoma otitis media: Our experience with 32 patients. Full Text available with Trip Pro

Postoperative efficacy analysis of patients with facial nerve palsy associated with cholesteatoma otitis media: Our experience with 32 patients. 29168315 2019 02 04 2019 02 15 1749-4486 43 2 2018 04 Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery Clin Otolaryngol Postoperative efficacy analysis of patients with facial nerve palsy associated with cholesteatoma otitis media: Our experience with 32 (...) , Shanghai, China. Shi H-B HB Otolaryngology Institute, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China. Chen Z-N ZN 0000-0001-7774-441X Otolaryngology Institute, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China. Yin S-K SK Otolaryngology Institute, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China. eng Journal Article 2017 12 20 England Clin Otolaryngol 101247023 1749-4478 IM Adult Cholesteatoma

2017 Clinical Otolaryngology

90. Complete Malleus Removal for Cholesteatoma: A Multivariate Analysis of Ossiculoplasty Success and Residual Disease. Full Text available with Trip Pro

Complete Malleus Removal for Cholesteatoma: A Multivariate Analysis of Ossiculoplasty Success and Residual Disease. Determine the effect of complete malleus removal during canal wall up tympanomastoidectomy for cholesteatoma on ossiculoplasty success and rate of residual cholesteatoma.We reviewed the operative, audiogram, and clinical reports of patients who underwent canal wall up tympanomastoidectomy for cholesteatoma between 2009 and 2016 at a tertiary academic medical center with at least 8 (...) months of follow-up after surgery. To control for extent of disease, we independently catalogued the subsites of the middle ear and mastoid that cholesteatoma involved from each operation. We performed multivariate logistic regression to determine the independent effect of complete removal of the malleus on the rate of residual disease and success of ossiculoplasty.One hundred eighty surgeries were included in the analysis. For ossiculoplasty success, the adjusted odds ratio of complete malleus

2017 Rhinology and Laryngology

91. Morphological Characteristics of Osseous External Auditory Canal and Its Relationship With External Auditory Canal Cholesteatoma in Patients With Congenital Aural Stenosis. (Abstract)

Morphological Characteristics of Osseous External Auditory Canal and Its Relationship With External Auditory Canal Cholesteatoma in Patients With Congenital Aural Stenosis. To investigate the characteristics of stenotic external auditory canal (EAC) (e.g., shape, length, orientation, and curvature) and to compare them with those of the cholesteatoma and no cholesteatoma groups, which may help to explain cholesteatoma formation to a certain degree.Computed tomography scans of two groups (...) of patients (with and without EAC cholesteatoma) were analyzed. We determined the degree of microtia, the stenosis of EAC, radius and curvature of osseous EAC bending (abbreviated as OEB-r and OEB-c, respectively), and other anatomic parameters of EAC by using Mimics and Matlab.There was no significant difference in the degree of microtia between the cholesteatoma and no cholesteatoma groups using the Marx grading system. Additionally, no significant difference was found in the stenosis of EAC between

2017 Otology and Neurotology

92. Value of T1-weighted Magnetic Resonance Imaging in Cholesteatoma Detection. (Abstract)

Value of T1-weighted Magnetic Resonance Imaging in Cholesteatoma Detection. To reveal the usefulness of T1-weighted (T1W) imaging on diagnostic magnetic resonance (MR) imaging for cholesteatoma.A retrospective case review.Tertiary referral center.Fifty-three patients (57 ears) suspected to have cholesteatomas and treated (6-82 yr of age).Preoperative MR imaging, including non-echo planar (non-EP) diffusion-weighted (DW) and T1W imaging.Primary outcome measures included the comparison between (...) the diagnostic accuracy for the detection of cholesteatomas using non-EP DW imaging alone (criterion 1) and non-EP DW imaging along with T1W imaging (criterion 2). Diagnostic accuracy was evaluated in each case by comparing MR imaging with surgical findings. Secondary outcome measures included the comparison of the rates of cases showing a high T1W signal between cholesteatomas and noncholesteatomas which showed a high non-EP DW signal.The sensitivity, specificity, and accuracy according to criterion 1 were

2017 Otology and Neurotology

93. Endoscopic versus microscopic approach in attic cholesteatoma surgery. (Abstract)

Endoscopic versus microscopic approach in attic cholesteatoma surgery. Compare the outcomes of primary exclusive endoscopic ear surgery with those of the microscopic ear surgery in a group of patients affected by attic cholesteatoma.Eighty patients suffered from attic cholesteatoma. Forty patients surgical treated with endoscopic ear surgery and forty patients surgical treated with microscopic ear surgery.No statistical differences were found in the parameters analysed (frequency of facial

2017 American Journal of Otolaryngology

94. Evidence against the mucosal traction theory in cholesteatoma. Full Text available with Trip Pro

Evidence against the mucosal traction theory in cholesteatoma. To investigate the distribution of ciliated epithelium in the human middle ear and its potential role in the formation of cholesteatoma.Comparative human temporal bone study.We selected temporal bones from 14 donors with a diagnosis of cholesteatoma, 15 with chronic otitis media without retraction pockets, 14 with chronic otitis media with retraction pockets, 14 with cystic fibrosis (CF), and 16 controls. We mapped the distribution (...) of the ciliated cells in the mucosal lining of the middle ear and tympanic membrane using three-dimensional reconstruction analysis, and counted the number of ciliated cells in the middle ear mucosa.Ciliated cells are extremely sparse in the epithelial lining of the lateral surface of the ossicles in the epitympanum and the medial surface of the tympanic membrane. Furthermore, there is a significant decrease in the number of ciliated cells in these areas in temporal bones with cholesteatoma, chronic otitis

2017 Laryngoscope

95. Association Between Middle Ear Cholesteatoma and Chronic Rhinosinusitis. Full Text available with Trip Pro

Association Between Middle Ear Cholesteatoma and Chronic Rhinosinusitis. Chronic rhinosinusitis (CRS) can cause an obstruction of the tubal orifice and thereby compromise ventilation of the middle ear. The resulting negative pressure in the middle ear may, in turn, lead to the formation of an eardrum retraction pocket and subsequent acquired cholesteatoma. This study hypothesizes that CRS may increase the risk of cholesteatoma.To evaluate the risk of cholesteatoma in patients with CRS.This (...) study used a nationwide, population-based claims database to test the hypothesis that CRS may increase the risk of cholesteatoma. The Longitudinal Health Insurance Database of Taiwan was used to compile data from (1) 12 670 patients with newly diagnosed CRS between January 1, 1997, and December 31, 2002, and (2) a comparison cohort of 63 350 matched individuals without CRS, resulting in a CRS vs control ratio of 1:5. Data analysis was performed from June 1 to October 27, 2015. Each patient

2017 JAMA otolaryngology-- head & neck surgery

96. Congenital cholesteatoma: Different clinical presentation in two cases Full Text available with Trip Pro

Congenital cholesteatoma: Different clinical presentation in two cases Congenital cholesteatoma (CC) of the middle ear is a rare entity that may be undiagnosed for years. The lesion can grow undetected until it produces symptoms such as reduced hearing or otalgia.Case report.We report two cases of young ladies with CC who presented with different otological symptoms. The first case complained of recurrent unilateral ear pain while the second case presented with unilateral reduced hearing

2016 Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia

97. Incidence of Facial Nerve Canal Dehiscence in Primary and Revision Cholesteatoma Surgery Full Text available with Trip Pro

Incidence of Facial Nerve Canal Dehiscence in Primary and Revision Cholesteatoma Surgery The aim of this retrospective study was to determine the incidence of facial canal dehiscence (FCD) in primary and revision cholesteatoma surgery in a tertiary referral center. Moreover, our second goal was to identify association between FCD and other intra-operative pathological findings in a group of patients with cholesteatoma surgery. Inclusion criteria were primary and revision canal wall up and canal (...) wall down tympanomastoidectomy in patients who suffers from chronic otitis media (COM) with cholesteatoma. An exclusion criterion was charts with in adequate documentation. In addition tympanoplasty cases were excluded due to evaluate both tympanic and mastoid segments of facial nerve canal. Preoperative clinical data and intra-operative findings were documented in a formatted questionnaire. We found the incidence of FCD in COM surgery was 18%. There was no difference between the primary

2017 Indian Journal of Otolaryngology and Head & Neck Surgery

98. A Case Report of a Giant Cholesteatoma Full Text available with Trip Pro

A Case Report of a Giant Cholesteatoma Cholesteatoma is a well demarcated, non-neoplastic, temporal bone cystic lesion with extensive keratinisation. Keratoma and epidermoid cyst are other possibly more accurate names suggested to describe the same. It can be classified as congenital or acquired. Its management is often complicated by its tendency to recidivism/recurrence. Long standing cholesteatomas can be a precursor for squamous cell carcinoma. We hereby present a case of giant (...) cholesteatoma in a 45-year-old female with radiological involvement of the left temporal region, periauricular region and infratemporal fossa with lytic destruction of left middle ear ossicles, mastoid and squamous part of temporal bone with intracranial extension. The enormity of the present lesion along with its bony erosions raised the strong clinical suspicion of malignancy. The underlying case report highlights the relevance of exhaustive sectioning and immunohistochemistry to reach the diagnosis.

2017 Journal of clinical and diagnostic research : JCDR

99. Diagnostic Bedside Vestibuloocular Reflex Evaluation in the Setting of a False Negative Fistula Test in Cholesteatoma of the Middle Ear Full Text available with Trip Pro

Diagnostic Bedside Vestibuloocular Reflex Evaluation in the Setting of a False Negative Fistula Test in Cholesteatoma of the Middle Ear Background. False negative fistula testing in patients with chronic suppurative otitis media is a dilemma when proceeding to surgery. It is imperative to rule out a dead labyrinth or a mass effect secondary to the cholesteatoma in an otherwise normally functioning inner ear. We present a case series of three patients in whom a bedside vestibuloocular reflex (...) (VOR) evaluation using a head impulse test was used successfully for further evaluation prior to surgery. Results. In all three cases with a false negative fistula test we were able to further evaluate at the bedside and were not only able to register the abnormal VOR but also localize its deterioration to a particular semicircular canal eroded by the fistula. Conclusion. Vestibuloocular reflex evaluation is mandatory in patients with suspected labyrinthine fistula due to cholesteatoma

2017 Case reports in otolaryngology

100. The accuracy and sensitivity of diffusion-weighted magnetic resonance imaging with Apparent Diffusion Coefficients in diagnosis of recurrent cholesteatoma Full Text available with Trip Pro

The accuracy and sensitivity of diffusion-weighted magnetic resonance imaging with Apparent Diffusion Coefficients in diagnosis of recurrent cholesteatoma To evaluate the accuracy and sensitivity of diffusion-weighted magnetic resonance imaging with ADC value combined with MDCT in evaluating recurrent cholesteatoma.Thirty patients (20 females and 10 males), their age ranged from 10 to 40years, had undergone a tympanomastoid surgery for a cholesteatoma of the middle ear underwent MDCT and MR DWI (...) examination before second- or third-look surgery from May 2015 to October 2016.CT showed partial opacification of the tympanomastoid cavity in 10 ears and complete opacification in 21 ears. CT detects 10 cases out of 20 cases of recurrent cholesteatoma with sensitivity 47.6%, specificity 100%, and NPP 47.6%. DWI depicted 21 out of 20 cases proved cholesteatoma patients (sensitivity 100%, specificity 90%, PPV 95.2% and P value is 0.001). All MRI of patients without cholesteatoma were correctly interpreted

2017 European Journal of Radiology Open

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