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Childhood Acute Neuropsychiatric Symptoms

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1. Childhood Acute Neuropsychiatric Symptoms

Childhood Acute Neuropsychiatric Symptoms Childhood Acute Neuropsychiatric Symptoms Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Childhood Acute Neuropsychiatric Symptoms Childhood Acute Neuropsychiatric Symptoms Aka: Childhood Acute Neuropsychiatric Symptoms , PANDAS , Pediatric Autoimmune Neuropsychiatric Disorders , Post-streptococcal Autoimmune Neuropsychiatric Disorder , Streptococcal Associated Neuropsychiatric Disorder II. Definition Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections III. Precautions Controversial diagnosis Streptococcal infection is common s are common When both

2018 FP Notebook

2. Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)

will be eligible if they: Are a biologic parent or sibling of an affected proband. Consent (or assent) to undergo study evaluations and to provide blood, microbial and genetic samples. Children with Non-PANS Neuropsychiatric Symptoms may be enrolled if they: Are 3 to 14 years of age (initial enrollment must occur prior to the participant s 15th birthday to permit prospective longitudinal evaluations) Have OCD, tics, anxiety disorders, or other psychiatric symptoms, but do NOT have a history of acute symptom (...) Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pediatric Acute-Onset Neuropsychiatric Syndrome

2018 Clinical Trials

3. Childhood Acute Neuropsychiatric Symptoms

Childhood Acute Neuropsychiatric Symptoms Childhood Acute Neuropsychiatric Symptoms Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Childhood Acute Neuropsychiatric Symptoms Childhood Acute Neuropsychiatric Symptoms Aka: Childhood Acute Neuropsychiatric Symptoms , PANDAS , Pediatric Autoimmune Neuropsychiatric Disorders , Post-streptococcal Autoimmune Neuropsychiatric Disorder , Streptococcal Associated Neuropsychiatric Disorder II. Definition Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections III. Precautions Controversial diagnosis Streptococcal infection is common s are common When both

2015 FP Notebook

4. Late Effects of Treatment for Childhood Cancer (PDQ®): Health Professional Version

care, and interventions to promote healthy living in the Childhood Cancer Survivor Study cohort. J Clin Oncol 27 (14): 2363-73, 2009. [ ] [ ] Schultz KA, Chen L, Chen Z, et al.: Health and risk behaviors in survivors of childhood acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer 55 (1): 157-64, 2010. [ ] [ ] Tercyak KP, Donze JR, Prahlad S, et al.: Multiple behavioral risk factors among adolescent survivors of childhood cancer in the Survivor Health (...) survivors of childhood cancer. J Cancer Surviv 1 (3): 237-45, 2007. [ ] Pui CH, Cheng C, Leung W, et al.: Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med 349 (7): 640-9, 2003. [ ] Park ER, Kirchhoff AC, Zallen JP, et al.: Childhood Cancer Survivor Study participants' perceptions and knowledge of health insurance coverage: implications for the Affordable Care Act. J Cancer Surviv 6 (3): 251-9, 2012. [ ] [ ] Warner EL, Park ER, Stroup A, et al.: Childhood

2018 PDQ - NCI's Comprehensive Cancer Database

5. Late Effects of Treatment for Childhood Cancer (PDQ®): Health Professional Version

care, and interventions to promote healthy living in the Childhood Cancer Survivor Study cohort. J Clin Oncol 27 (14): 2363-73, 2009. [ ] [ ] Schultz KA, Chen L, Chen Z, et al.: Health and risk behaviors in survivors of childhood acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer 55 (1): 157-64, 2010. [ ] [ ] Tercyak KP, Donze JR, Prahlad S, et al.: Multiple behavioral risk factors among adolescent survivors of childhood cancer in the Survivor Health (...) survivors of childhood cancer. J Cancer Surviv 1 (3): 237-45, 2007. [ ] Pui CH, Cheng C, Leung W, et al.: Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med 349 (7): 640-9, 2003. [ ] Park ER, Kirchhoff AC, Zallen JP, et al.: Childhood Cancer Survivor Study participants' perceptions and knowledge of health insurance coverage: implications for the Affordable Care Act. J Cancer Surviv 6 (3): 251-9, 2012. [ ] [ ] Warner EL, Park ER, Stroup A, et al.: Childhood

2016 PDQ - NCI's Comprehensive Cancer Database

6. Clinical Presentation of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections in Research and Community Settings. (PubMed)

etiology of symptoms. Although difficulties in documenting an association between GAS infection and symptom onset/exacerbations may preclude a diagnosis of PANDAS in some children with acute-onset OCD, they do appear to meet criteria for pediatric acute-onset neuropsychiatric syndrome (PANS). (...) Clinical Presentation of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections in Research and Community Settings. The first cases of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) were described >15 years ago. Since that time, the literature has been divided between studies that successfully demonstrate an etiologic relationship between Group A streptococcal (GAS) infections and childhood-onset obsessive

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2015 Journal of Child and Adolescent Psychopharmacology

7. Study to Evaluate Efficacy and Safety of Roluperidone (MIN-101) in Adult Patients With Negative Symptoms of Schizophrenia

before screening into the trial. Patient is stable in terms of positive and negative symptoms of schizophrenia over the last 6 months according to his or her treating psychiatrist and based on documentation in the clinical chart. Patient is currently an outpatient and has not been hospitalized for the last 6 months for acute exacerbation or symptoms worsening. Patients hospitalized during the last 6 months for social reasons or are currently hospitalized for social reasons can be included only (...) Study to Evaluate Efficacy and Safety of Roluperidone (MIN-101) in Adult Patients With Negative Symptoms of Schizophrenia Study to Evaluate Efficacy and Safety of Roluperidone (MIN-101) in Adult Patients With Negative Symptoms of Schizophrenia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2017 Clinical Trials

8. Family-based CBT for early childhood OCD: efficient for white, non-minority, upper middle-class children

of OCD according to the DSM-IV-TR, clinical relevant symptoms as defined by a score of 16 or higher on the Children’s Yale-Brown Obsessive Compulsive Scale (CY-BOCS). Symptoms had to be stable for 3 months or longer and children had to be outpatients. Children with pervasive developmental disorders, as were those diagnosed with pediatric neuropsychiatric disorders associated with strep infection (PANDAS) or with acute suicidality, were excluded. Also excluded were children who were undergoing (...) Family-based CBT for early childhood OCD: efficient for white, non-minority, upper middle-class children Family-based CBT for early childhood OCD Search National Elf Service Search National Elf Service » » » » Family-based CBT for early childhood OCD: efficient for white, non-minority, upper middle-class children Sep 24 2014 Posted by Early childhood-onset obsessive-compulsive disorder (OCD) has disruptive consequences in terms of social, family and academic functioning and a negative impact

2014 The Mental Elf

9. Acute Pain Management: Scientific Evidence

from symptom management to the creation of the discipline of acute pain medicine. This discipline is rapidly changing. Valid and pragmatic assessment of acute pain is essential for effective pain management ( Gordon 2015). This is the fourth edition of Acute Pain Management: Scientific Evidence. The first three were published in 1999, 2005 and 2010, respectively. The first edition was written by a multidisciplinary committee headed up by Professor Michael Cousins of the University of Sydney (...) Acute Pain Management: Scientific Evidence ACUTE PAIN MANAGEMENT: SCIENTIFIC EVIDENCE Fourth Edition 2015 Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine Edited by: Stephan A Schug Greta M Palmer David A Scott Richard Halliwell Jane T rinca© Australian and New Zealand College of Anaesthetists 2015 ISBN Print: 978-0-9873236-7-5 Online: 978-0-9873236-6-8 This work is copyright. Apart from any use as permitted under the Copyright Act 1968, no part may be reproduced

2015 Clinical Practice Guidelines Portal

10. Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS): An Evolving Concept (PubMed)

behavioral features, in addition to obsessive-compulsive symptoms and tics, have been included in pediatric acute-onset neuropsychiatric syndromes (PANS) and childhood acute neuropsychiatric syndromes (CANS), two new concepts recently proposed in order to define a much broader clinical spectrum encompassing etiologically diverse entities. Given the uncertainties on the clinical definition of PANDAS, it is not surprising that evidence in support of a post-infectious, immune-mediated pathophysiology (...) Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS): An Evolving Concept Pediatric autoimmune neuropsychiatric disorders associated with streptococcus infections (PANDAS) originated from the observational work of Swedo and collaborators, who formalized their definition in 1998 in a set of operational criteria. The application of these criteria, which focuses on tics and obsessive-compulsive symptoms as core symptoms, has encountered difficulties

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2013 Tremor and Other Hyperkinetic Movements

11. Prevalence of Acute-Onset Subtypes in Pediatric Obsessive-Compulsive Disorder. (PubMed)

Prevalence of Acute-Onset Subtypes in Pediatric Obsessive-Compulsive Disorder. Pediatric obsessive-compulsive disorder (OCD) is a common, debilitating illness. When childhood OCD symptom onset is described as acute and severe, diagnostic criteria for pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS) should be considered. However, the frequency and differentiating features of these putative (...) symptoms, and had greater OCD-related family impairment during their worst OCD episode.A small yet significant percentage of pediatric OCD outpatients met criteria for PANDAS and/or PANS, justifying routine screening and attention to related characteristics during assessment and management. Longitudinal studies of these putative subtypes are warranted.

2017 Journal of Child and Adolescent Psychopharmacology

12. The Australian guideline for prevention, diagnosis and management of acute rheumatic fever and rheumatic heart disease

in individuals with RHD to reduce symptoms and disability, and prevent premature death. Primordial and primary prevention of acute rheumatic fever Primordial prevention aims to stop the development of risk factors for a disease in a population. In the case of ARF and RHD, primordial prevention means preventing GAS infections through implementing actions and measures that target environmental, economic, social and behavioural conditions, and cultural patterns of living that are known to increase the risk (...) The Australian guideline for prevention, diagnosis and management of acute rheumatic fever and rheumatic heart disease The Australian guideline for prevention, diagnosis and management of acute rheumatic fever and rheumatic heart disease (2nd edition)Lead authors Professor Jonathan Carapetis (Chair); Professor Alex Brown; Associate Professor Graeme Maguire; Dr Warren Walsh Ms Sara Noonan; Mr Dale Thompson (Coordination and Secretariat) Major contributors Mr Marc Rémond; Dr Bo Remenyi; Dr Andrew

2012 Clinical Practice Guidelines Portal

13. Late Effects of Treatment for Childhood Cancer

TO, et al.: Health behaviors, medical care, and interventions to promote healthy living in the Childhood Cancer Survivor Study cohort. J Clin Oncol 27 (14): 2363-73, 2009. Schultz KA, Chen L, Chen Z, et al.: Health and risk behaviors in survivors of childhood acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer 55 (1): 157-64, 2010. Tercyak KP, Donze JR, Prahlad S, et al.: Multiple behavioral risk factors among adolescent survivors of childhood cancer (...) cancer. J Cancer Surviv 1 (3): 237-45, 2007. Pui CH, Cheng C, Leung W, et al.: Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med 349 (7): 640-9, 2003. Park ER, Kirchhoff AC, Zallen JP, et al.: Childhood Cancer Survivor Study participants' perceptions and knowledge of health insurance coverage: implications for the Affordable Care Act. J Cancer Surviv 6 (3): 251-9, 2012. Warner EL, Park ER, Stroup A, et al.: Childhood cancer survivors' familiarity

2012 PDQ - NCI's Comprehensive Cancer Database

14. Pervasive Developmental Disorder: Childhood Disintegration Disorder (Diagnosis)

to be consoled and may even withdraw from human (tactile) contact. The disorder may be associated with lysosomal storage disorders such as late-onset Tay-Sachs disease(LOTS). A case report of a patient with symptoms of childhood disintegrative disorder at age 4 years determined that the patient had a sialylation deficiency and an increase of asialo-core fucosylated bisected N-glycans, aberrant N-glycan structures of CSF even though there were no changes of total plasma N-glycan strucutres of CSF proteins (...) . [ ] Additional symptoms of childhood disintegrative disorder may include the onset of difficulty in the transition to waking from sleep. Social interactions become compromised (as manifested by aggressiveness, tantrums, or withdrawal from peers), as does motor function, resulting in poor coordination and possible awkwardness of gait. [ ] Overall, the social, communicative, and behavioral features of childhood disintegrative disorder resemble those of . Affected children have distinct qualitative impairments

2014 eMedicine Pediatrics

15. Pervasive Developmental Disorder: Childhood Disintegration Disorder (Overview)

to be consoled and may even withdraw from human (tactile) contact. The disorder may be associated with lysosomal storage disorders such as late-onset Tay-Sachs disease(LOTS). A case report of a patient with symptoms of childhood disintegrative disorder at age 4 years determined that the patient had a sialylation deficiency and an increase of asialo-core fucosylated bisected N-glycans, aberrant N-glycan structures of CSF even though there were no changes of total plasma N-glycan strucutres of CSF proteins (...) . [ ] Additional symptoms of childhood disintegrative disorder may include the onset of difficulty in the transition to waking from sleep. Social interactions become compromised (as manifested by aggressiveness, tantrums, or withdrawal from peers), as does motor function, resulting in poor coordination and possible awkwardness of gait. [ ] Overall, the social, communicative, and behavioral features of childhood disintegrative disorder resemble those of . Affected children have distinct qualitative impairments

2014 eMedicine Pediatrics

16. Pervasive Developmental Disorder: Childhood Disintegration Disorder (Treatment)

approved by the FDA for the treatment of irritability associated with childhood autism. [ , , , ] These medications can be useful in treating associated symptoms of irritability, aggression, and hyperactivity. Citalopram has not been proved effective, and fluoxetine often causes undesirable gastrointestinal (GI) side effects in this population. [ , , , , ] Children who present with markedly impaired attention may improve when treated with very low doses of stimulants or nonstimulants (eg (...) with acutely disturbed behavior and psychotic symptoms, these medications should be considered for short-term use or to decrease the antipsychotic dose when used in combination. They do not cause malignant neuroleptic or metabolic syndrome or prolongation of the QT interval, which can occur with antipsychotics (eg, haloperidol) or atypical antipsychotics. [ ] In situations in which symptoms of catatonia are present (silence [mutism], tenseness and rigidity [holds back acts that are compelled by memories

2014 eMedicine Pediatrics

17. Pervasive Developmental Disorder: Childhood Disintegration Disorder (Follow-up)

approved by the FDA for the treatment of irritability associated with childhood autism. [ , , , ] These medications can be useful in treating associated symptoms of irritability, aggression, and hyperactivity. Citalopram has not been proved effective, and fluoxetine often causes undesirable gastrointestinal (GI) side effects in this population. [ , , , , ] Children who present with markedly impaired attention may improve when treated with very low doses of stimulants or nonstimulants (eg (...) with acutely disturbed behavior and psychotic symptoms, these medications should be considered for short-term use or to decrease the antipsychotic dose when used in combination. They do not cause malignant neuroleptic or metabolic syndrome or prolongation of the QT interval, which can occur with antipsychotics (eg, haloperidol) or atypical antipsychotics. [ ] In situations in which symptoms of catatonia are present (silence [mutism], tenseness and rigidity [holds back acts that are compelled by memories

2014 eMedicine Pediatrics

18. Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

and treatment protocol designed to provide opportunities for identifying new clinical syndromes, providing cases for instruction and training, and permitting longitudinal assessments of a variety of childhood behavioral, psychiatric and developmental disorders. Disorders of particular interest are: autism, disorders of social cognition and other neurodevelopmental disorders; childhood psychiatric disorders and particularly those with acute symptom onset; and unique clinical presentations of pediatric (...) table for study information Study Type : Observational Estimated Enrollment : 3500 participants Observational Model: Cohort Time Perspective: Other Official Title: Diagnosis and Treatment of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders Study Start Date : January 26, 2013 Estimated Primary Completion Date : July 6, 2020 Estimated Study Completion Date : July 6, 2020 Groups and Cohorts Go to Outcome Measures Go to Primary Outcome Measures : Gain

2013 Clinical Trials

19. Porphyria, Acute (Follow-up)

after a menses-elicited acute episode resolved. Use of a testosterone implant is reported in 1 case. Previous Next: Complications Hypertension and chronic renal insufficiency may occur. Recurrent acute episodes increase the risk of neuropsychiatric symptoms during the symptomless phase of the disease. For more than 90% of women, pregnancy does not exacerbate symptoms of porphyria or lead to acute episodes. However, approximately 8% of women may have symptoms of porphyria during pregnancy (...) own deleterious effects. Therefore, oral contraceptives (eg, a low-dose estrogen-progesterone combination pill) may be useful, if tolerated. Standard oral contraceptive pills may elicit porphyria symptoms (in 15% of patients) or episodes (in 5% of patients). However, in several cases, further episodes were prevented with the administration of oral contraceptive pills (especially low-dose estrogen or an estrogen-progesterone combination) immediately after a menses-elicited acute episode resolved

2014 eMedicine Pediatrics

20. Pyelonephritis, Acute (Treatment)

=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjQ1NTU5LXRyZWF0bWVudA== processing > Acute Pyelonephritis Treatment & Management Updated: Dec 12, 2018 Author: Tibor Fulop, MD, PhD, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN Share Email Print Feedback Close Sections Sections Acute Pyelonephritis Treatment Approach Considerations Ambulatory younger women who present with signs and symptoms of uncomplicated acute pyelonephritis may be candidates for outpatient therapy. They must be otherwise healthy and must not be pregnant. In addition, they must (...) demonstrated resolution of symptoms and a negative urine culture, compared with about 73% of patients treated with piperacillin–tazobactam. [ ] Previous Next: Outpatient Treatment Antibiotic therapy Patients presenting with acute pyelonephritis can be treated with a single dose of a parenteral antibiotic followed by oral therapy, provided they are monitored within the first 48 hours. In a study of febrile, nonpregnant women presenting with symptoms of acute pyelonephritis, 25% were hospitalized

2014 eMedicine.com

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