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Chancroid

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101. Cervicitis (Overview)

with a curable STI (trichomoniasis, chlamydia, syphilis, or gonorrhea) every year. [ ] Other STIs are caused by various bacterial (chancroid, donovanosis) and viral (eg, human immunodeficiency virus [HIV], hepatitis B virus [HBV], cytomegalovirus [CMV]) pathogens, as well as by parasites (vaginal trichomoniasis, vulvovaginitis, balanoposthitis [men]). [ ] Human papillomavirus The prevalence of HPV, a cause of , varies roughly 20-fold internationally. In various studies, the seroprevalence of HSV-2 is higher

2014 eMedicine.com

102. Dermatologic Diseases of the Male Genitalia: Nonmalignant (Overview)

diagnoses The differential diagnoses include granuloma inguinale (see ), chancroid, herpesvirus infection, and syphilis (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate or ulcer smears, and appropriate microbiological culture. Anorectal involvement can mimic the clinical presentation of inflammatory bowel disease. Treatment and outcome The recommended treatment is 100 mg PO bid for 21 days. Oral erythromycin 500 mg qid for 21 days (...) or polymerase chain reaction (PCR) performed on lesional tissue. A rise in titer suggests reinfection or treatment failure. Microbiologic culture is not used, as the spirochete T pallidum has not been successfully cultured. [ , , , , , ] Differential diagnoses The differential diagnoses include chancroid (see ), granuloma inguinale (see ), herpesvirus infection, and LGV (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate or ulcer smears

2014 eMedicine.com

103. Dermatologic Aspects of Bioterrorism Agents (Overview)

include the following: Tularemia Chancroid TB Streptococcal adenitis Scrub typhus The differential diagnosis of septicemic plague also includes meningococcemia, gram-negative sepsis, and rickettsioses. A presentation of systemic toxicity, a productive cough, and bloody sputum suggests a large differential diagnosis. However, demonstration of gram-negative coccobacilli in the sputum readily should suggest the correct diagnosis, because Y pestis is perhaps the only gram-negative bacterium that can cause

2014 eMedicine.com

105. Benign Cervical Lesions (Follow-up)

, doxycycline at 100 mg twice daily for 2 weeks by mouth or tetracycline at 500 mg 4 times/d by mouth for 2 weeks is acceptable. If the patient is pregnant, desensitization followed by treatment with penicillin is recommended. All patients with a diagnosis of syphilis should be tested for HIV. Hemophilus ducreyi The primary ulcer is a painless chancroid and is typically on the fourchette, labia, or vestibule. Vaginal wall ulcers can occur and, at times, involve the cervix. Involvement of the cervix alone

2014 eMedicine.com

106. Paraphimosis (Diagnosis)

position sometimes leads to the development of paraphimosis. More unusual causes of paraphimosis include the following: Self-infliction, such as piercing with a penile ring into the glans [ ] Placement of a preputial bead Erotic dancing [ ] P lasmodium falciparum infection [ ] Contact dermatitis (eg, from the application of celandine juice to the foreskin [ ] ) Haemophilus ducreyi infection (chancroid) [ ] Previous Next: Pathophysiology When the foreskin becomes trapped behind the corona (...) and International Health . 7 July 2008. Vol 5:906-907. . . Gozal D. Paraphimosis apparently associated with Plasmodium falciparum infection. Transactions of the Royal Society of Tropical Medicine and Hygiene . July-August 1991. 85:443. . . Farina LA, Alonso MV, Horjales M, Zungri ER. Contact-derived allergic balanoposthitis and paraphimosis through topical application of celandine juice. Actas Urologicas Españolas . June 1999. 23:554-555. . Harvey K, Bishop L, Silver D, Jones T. A case of chancroid. The Medical

2014 eMedicine.com

107. Dermatologic Diseases of the Male Genitalia: Nonmalignant (Follow-up)

. [ ] Differential diagnoses The differential diagnoses include granuloma inguinale (see ), chancroid, herpesvirus infection, and syphilis (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate or ulcer smears, and appropriate microbiological culture. Anorectal involvement can mimic the clinical presentation of inflammatory bowel disease. Treatment and outcome The recommended treatment is 100 mg PO bid for 21 days. Oral erythromycin 500 mg qid for 21 (...) lesional tissue or polymerase chain reaction (PCR) performed on lesional tissue. A rise in titer suggests reinfection or treatment failure. Microbiologic culture is not used, as the spirochete T pallidum has not been successfully cultured. [ , , , , , ] Differential diagnoses The differential diagnoses include chancroid (see ), granuloma inguinale (see ), herpesvirus infection, and LGV (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate

2014 eMedicine.com

108. Paraphimosis (Follow-up)

D. Paraphimosis apparently associated with Plasmodium falciparum infection. Transactions of the Royal Society of Tropical Medicine and Hygiene . July-August 1991. 85:443. . . Farina LA, Alonso MV, Horjales M, Zungri ER. Contact-derived allergic balanoposthitis and paraphimosis through topical application of celandine juice. Actas Urologicas Españolas . June 1999. 23:554-555. . Harvey K, Bishop L, Silver D, Jones T. A case of chancroid. The Medical Journal of Australia . 1977. 26:956-957

2014 eMedicine.com

110. Dermatologic Diseases of the Male Genitalia: Nonmalignant (Treatment)

. [ ] Differential diagnoses The differential diagnoses include granuloma inguinale (see ), chancroid, herpesvirus infection, and syphilis (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate or ulcer smears, and appropriate microbiological culture. Anorectal involvement can mimic the clinical presentation of inflammatory bowel disease. Treatment and outcome The recommended treatment is 100 mg PO bid for 21 days. Oral erythromycin 500 mg qid for 21 (...) lesional tissue or polymerase chain reaction (PCR) performed on lesional tissue. A rise in titer suggests reinfection or treatment failure. Microbiologic culture is not used, as the spirochete T pallidum has not been successfully cultured. [ , , , , , ] Differential diagnoses The differential diagnoses include chancroid (see ), granuloma inguinale (see ), herpesvirus infection, and LGV (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate

2014 eMedicine.com

112. Benign Cervical Lesions (Treatment)

, doxycycline at 100 mg twice daily for 2 weeks by mouth or tetracycline at 500 mg 4 times/d by mouth for 2 weeks is acceptable. If the patient is pregnant, desensitization followed by treatment with penicillin is recommended. All patients with a diagnosis of syphilis should be tested for HIV. Hemophilus ducreyi The primary ulcer is a painless chancroid and is typically on the fourchette, labia, or vestibule. Vaginal wall ulcers can occur and, at times, involve the cervix. Involvement of the cervix alone

2014 eMedicine.com

113. Cervicitis (Diagnosis)

with a curable STI (trichomoniasis, chlamydia, syphilis, or gonorrhea) every year. [ ] Other STIs are caused by various bacterial (chancroid, donovanosis) and viral (eg, human immunodeficiency virus [HIV], hepatitis B virus [HBV], cytomegalovirus [CMV]) pathogens, as well as by parasites (vaginal trichomoniasis, vulvovaginitis, balanoposthitis [men]). [ ] Human papillomavirus The prevalence of HPV, a cause of , varies roughly 20-fold internationally. In various studies, the seroprevalence of HSV-2 is higher

2014 eMedicine.com

114. Dermatologic Diseases of the Male Genitalia: Nonmalignant (Diagnosis)

. [ ] Differential diagnoses The differential diagnoses include granuloma inguinale (see ), chancroid, herpesvirus infection, and syphilis (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate or ulcer smears, and appropriate microbiological culture. Anorectal involvement can mimic the clinical presentation of inflammatory bowel disease. Treatment and outcome The recommended treatment is 100 mg PO bid for 21 days. Oral erythromycin 500 mg qid for 21 (...) lesional tissue or polymerase chain reaction (PCR) performed on lesional tissue. A rise in titer suggests reinfection or treatment failure. Microbiologic culture is not used, as the spirochete T pallidum has not been successfully cultured. [ , , , , , ] Differential diagnoses The differential diagnoses include chancroid (see ), granuloma inguinale (see ), herpesvirus infection, and LGV (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate

2014 eMedicine.com

116. Benign Cervical Lesions (Diagnosis)

, doxycycline at 100 mg twice daily for 2 weeks by mouth or tetracycline at 500 mg 4 times/d by mouth for 2 weeks is acceptable. If the patient is pregnant, desensitization followed by treatment with penicillin is recommended. All patients with a diagnosis of syphilis should be tested for HIV. Hemophilus ducreyi The primary ulcer is a painless chancroid and is typically on the fourchette, labia, or vestibule. Vaginal wall ulcers can occur and, at times, involve the cervix. Involvement of the cervix alone

2014 eMedicine.com

117. Lymphogranuloma Venereum (Diagnosis)

venereum in men screened for pharyngeal and rectal infection, Germany. Emerg Infect Dis . 2013 Mar. 19(3):488-92. . Templeton DJ, Sharp N, Gryllis S, O'Connor CC, Dubedat SM. Prevalence and predictors of lymphogranuloma venereum among men who have sex with men at a Sydney metropolitan sexual health clinic. Sex Health . 2013 Apr. 10(2):190-1. . Basta-Juzbašić A, Čeović R. Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum. Clin Dermatol (...) , Barkin R, Braen G, eds. Emergency Medicine Concepts and Clinical Practice . 3rd ed. Mosby-Year Book; 1992. 1966. Ronald A, Alfa M. Chancroid, lymphogranuloma venereum, and granuloma inguinale. In: Gorbach S, Bartlett J, and Blacklow N, eds. Infectious Diseases. 2nd ed . Philadelphia, Pa: WB Saunders Co. 1998:1012-3. Sparling P. Sexually transmitted disease. Wyngaarden J, Smith L, and Bennett J, eds. Cecil Textbook of Medicine . 19th ed. Philadelphia, Pa: WB Saunders Co; 1992. 1759-61. Stamm W, Holmes

2014 eMedicine Emergency Medicine

118. Lymphogranuloma Venereum (Follow-up)

sexual health clinic. Sex Health . 2013 Apr. 10(2):190-1. . Basta-Juzbašić A, Čeović R. Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum. Clin Dermatol . 2014 Mar-Apr. 32 (2):290-8. . Rönn M, Hughes G, Simms I, Ison C, Alexander S, White PJ, et al. Challenges Presented by Re-Emerging Sexually Transmitted Infections in HIV Positive Men who have Sex with Men: An Observational Study of Lymphogranuloma Venereum in the UK. J AIDS Clin (...) . 78(2):90-2. . Perine P, Osoba A. Lymphogranuloma venereum. Holmes K, Mardh P, Sparling P, eds. Sexually Transmitted Diseases . New York, NY: McGraw-Hill Inc; 1990. 195-202. Pointer J. Genital infections. Rosen P, Barkin R, Braen G, eds. Emergency Medicine Concepts and Clinical Practice . 3rd ed. Mosby-Year Book; 1992. 1966. Ronald A, Alfa M. Chancroid, lymphogranuloma venereum, and granuloma inguinale. In: Gorbach S, Bartlett J, and Blacklow N, eds. Infectious Diseases. 2nd ed . Philadelphia, Pa

2014 eMedicine Emergency Medicine

119. Paraphimosis (Treatment)

D. Paraphimosis apparently associated with Plasmodium falciparum infection. Transactions of the Royal Society of Tropical Medicine and Hygiene . July-August 1991. 85:443. . . Farina LA, Alonso MV, Horjales M, Zungri ER. Contact-derived allergic balanoposthitis and paraphimosis through topical application of celandine juice. Actas Urologicas Españolas . June 1999. 23:554-555. . Harvey K, Bishop L, Silver D, Jones T. A case of chancroid. The Medical Journal of Australia . 1977. 26:956-957

2014 eMedicine.com

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