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Cervical Examination in Labor

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161. Effect of reproductive ageing on pregnant mouse uterus and cervix Full Text available with Trip Pro

) and 5 months (intermediate) vs. 8 months (older) of age using infrared video recording. Serum progesterone profiles, myometrium and cervix function, and mitochondrial electron transport chain complex enzymatic activities were also examined. Older pregnant mice had a longer mean gestation and labour duration (P < 0.001), as well as reduced litter size (P < 0.01) vs. 3-month-old mice. Older mice did not exhibit the same decline in serum progesterone concentrations as younger mice. Cervical tissues (...) Effect of reproductive ageing on pregnant mouse uterus and cervix Older pregnant women have a greater risk of operative delivery, still birth and post-term induction. This suggests that maternal age can influence the timing of birth and processes of parturition. We have found that increasing maternal age in C57BL/6J mice is associated with prolongation of gestation and length of labour. Older pregnant mice also had delayed progesterone withdrawal and impaired myometrial function. Uterine ageing

2017 The Journal of physiology

162. Elastographic measurement of the cervix during pregnancy: Current status and future challenges Full Text available with Trip Pro

Elastographic measurement of the cervix during pregnancy: Current status and future challenges The cervix is a cylindrical structure that is proximally connected to the uterus and distally to the vaginal cavity. The Bishop score has been used to evaluate the cervix during pregnancy. However, alternatives have been evaluated because the Bishop score is uncomfortable for patients, relies on a subjective examination, and lacks internal os data. Elastography has been used to assess the cervix (...) , as it can estimate tissue stiffness. Recent articles on elastography for cervical assessment during pregnancy have focused on its usefulness for prediction of preterm birth and successful labor induction. There is a clinical need for cervical elastography, as an evaluation of biomechanical factors, because cervical length only assesses morphological changes. However, until now, cervical elastography has been studied in the limited field, and not shown a uniformed methodological technique. In this review

2017 Obstetrics & gynecology science

163. Cervical gland area as an ultrasound marker for prediction of preterm delivery: A cohort study Full Text available with Trip Pro

Cervical gland area as an ultrasound marker for prediction of preterm delivery: A cohort study Preterm labor is a major cause of perinatal morbidity and mortality and it might be predicted by assessing the cervical change.To assess the association between absence of cervical gland area (CGA) and spontaneous preterm labor (SPTL).This prospective cohort study was performed on 200 singleton pregnant women with a history of SPTL, second-trimester abortion in the previous pregnancy or lower (...) abdominal pain in current pregnancy. Each patient underwent one transvaginal ultrasound examination between 14-28 wk of gestation. Cervical length was measured and CGA was identified and their relationship with SPTL before 35 and 37 wk gestation was evaluated using STATA software version 10.The mean of cervical length was 36.5 mm (SD=8.4), the shortest measurement was 9 mm, and the longest one was 61 mm. Short cervical length (≤18mm) was significantly associated with SPTL before 35 and 37 wk

2017 International Journal of Reproductive Biomedicine

164. Inpatient Versus Outpatient Cervical Ripening

): Rebecca Pierce-Williams, LifeBridge Health Study Details Study Description Go to Brief Summary: Induction of labor is a process of stimulating uterine contractions before the onset of labor, with a goal of achieving vaginal birth. The cervix (the lower part of the uterus that connects to the vagina) must dilate (open) in order to allow passage of the baby into the vagina and through the birth canal. A process called "cervical ripening" is often performed prior to labor induction to prepare the cervix (...) for labor and therefore shorten the length of the labor. There are various pharmacologic and mechanical methods of cervical ripening that result in the physical softening and distensibility of the cervix. Mechanical dilation with a small balloon (i.e. a Foley catheter) placed in the cervix is one of the most commonly used, safe, inexpensive, and effective methods to achieve cervical ripening. In most hospitals, cervical ripening is performed in the hospitals; however, some hospitals allow women

2017 Clinical Trials

165. Dinoprostone Vaginal Insert Versus Double Balloon Catheter for Preinduction Cervical Ripening

vaginal examination just prior to that examination. In the group assigned to mechanical ripening , a double- balloon catheter (Cook Cervical Ripener Balloon,Cook OB/GYN,Spencer IN) is inserted into cervical canal under direct visualisation during a sterile speculum examination. Once both balloon enter the cervical canal, the first balloon is filled with 40 ml saline above the level of the internal os. The second (vaginal) balloon is the inflated with 20 ml of saline.Then both of them are filled (...) : April 2017 Resource links provided by the National Library of Medicine available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Cook double balloon catheter A double- balloon catheter (Cook Cervical Ripener Balloon,Cook OB/GYN,Spencer IN) is inserted into cervical canal under direct visualisation during a sterile speculum examination İt is placed for 12 hours Device: Cook Double Balloon Catheter A double- balloon catheter (Cook Cervical Ripener Balloon,Cook OB/GYN,Spencer

2017 Clinical Trials

166. Cervical Recuperation After Vaginal Delivery

): ROY LAUTERBACH MD, Rambam Health Care Campus Study Details Study Description Go to Brief Summary: Patients after vaginal delivery will undergo 3 trans-vaginal ultrasounds in order to examine the process of cervical recuperation post delivery. Condition or disease Intervention/treatment Cervix Device: Trans-vaginal ultrasound Detailed Description: Patients after vaginal delivery will be recruited after receiving a full explanation and signing an informed consent. The goal of the study is to examine (...) cervical length after vaginal delivery at 3 different time intervals: 8 hours post delivery. 24 hours post delivery. 48 hours post delivery. At each interval a trans-vaginal ultrasound will be performed, evaluating cervical length. At the end of the 3rd and final ultrasound, the patient will finish her participation in the study/ Information regarding obstetric conditions such as labor induction, gestational age at the time of delivery etc. will be collected from patients` electronic files. Study

2017 Clinical Trials

167. Short Cervix

with twin gestations and short cervix diagnosed via ultrasound. A significant reduction in the rate of preterm birth prior to 34 weeks was found in the pessary group (16.2% vs 39.4%), with no significant differences in neonatal morbidity or mortality. Chart review will collect information documented on the data collection sheet, including medical and OB history, current pregnancy course, treatment for short cervix and information on hospitalization including labor and delivery, postpartum course (...) and neonatal birth information. The investigators will analyses and compare this group of women using short cervix diagnosis, management decisions and outcomes during the antepartum period, labor, delivery and post partum course for possible signs and symptoms of those at risk for Pre Term Birth and outcomes of their infants. Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 6 participants Observational Model: Cohort Time Perspective: Retrospective

2017 Clinical Trials

168. Cervical Ripening With the Double Balloon Device for 6 Hours Compared With 12 Hours

8, 2017 Last Update Posted : March 5, 2019 See Sponsor: Bnai Zion Medical Center Information provided by (Responsible Party): Inna.bleicher, Bnai Zion Medical Center Study Details Study Description Go to Brief Summary: This study will evaluate the insertion of double balloon device (DBD) for cervical ripening for 12 h vs 6 hours. Condition or disease Intervention/treatment Phase Induction of Labor Unfavorable Cervix Device: cervical ripening device Not Applicable Detailed Description (...) Posted: March 5, 2019 Last Verified: March 2019 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Inna.bleicher, Bnai Zion Medical Center: cervical ripening labor induction double balloon device cervical ripening device unfavorable cervix Additional relevant MeSH terms: Layout table for MeSH terms Oxytocin Oxytocics Reproductive Control Agents Physiological Effects of Drugs

2017 Clinical Trials

169. Cerclage for Twins With Short Cervix

Center for Research, Education, Quality and Safety Study Details Study Description Go to Brief Summary: A prospective randomized control trial that will compare cervical cerclage plus vaginal progesterone to vaginal progesterone along in twin pregnancies complicate by a short cervix (Labor With Preterm Delivery, Unspecified Trimester, Fetus 2 Cervical Incompetence Cervical Shortening Procedure (...) : Cervical Cerclage placement Drug: Vaginal Progesterone Phase 2 Phase 3 Detailed Description: A prospective Randomized Trial that will test whether treatment with cervical cerclage plus vaginal progesterone improves pregnancy outcomes among women with twin pregnancy at 16 0/7 to 25 6/7 weeks of gestation who have a cervical length (CL) of 0.1 to 15.0 mm on transvaginal ultrasound exam, the rate of preterm birth at less than 32 weeks of gestation (PTB<32 wks.) and the rate of adverse perinatal outcome

2017 Clinical Trials

170. Value of Measuring Cervical Angle and Length by Ultrasound in Prediction of Successful Induction of Delivery

Posted : July 17, 2017 Sponsor: Cairo University Information provided by (Responsible Party): Eman Omran, Cairo University Study Details Study Description Go to Brief Summary: Seventy ladies indicated for induction of delivery will be recruited. Two ways of assessment of their cervices will be done before actual induction of labor. First, ultrasound will be done to assess the angle and the length of the cervix. Then vaginal examination will be done to assess the characteristics of cervix. Analysis (...) will be done to identify the best predictor of successful induction of labour. Condition or disease Intervention/treatment Phase Induced; Birth Diagnostic Test: Transvaginal ultrasound Diagnostic Test: Vaginal examination Not Applicable Detailed Description: Seventy patients indicated for induction of labor will be recruited. Two ways of assessment of their cervices will be done before actual induction of labor. First, transvaginal ultrasound will be done to assess the posterior angle and the length

2017 Clinical Trials

171. Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices

of membranes (PROM). Prospective randomized studies comparing IBC placement to oxytocin use in induction of labor for term PROM do not exist. Intracervical Balloon Catheter has been shown to reduce duration of labor for women with intact membranes undergoing induction of labor. The practice at this institution is to use oxytocin to start contractions when a woman has PROM. This study will examine IBC compared to oxytocin use in term PROM. This will allow for the evaluation of a cervical ripening method (...) the bag of water prior to onset of labor. The investigators suspect that an intracervical balloon catheter will shorten the time interval from initiation of induction of labor to delivery. Condition or disease Intervention/treatment Phase Premature Rupture of Membrane Unfavorable Cervix Device: Intracervical balloon catheter Drug: Oxytocin Not Applicable Detailed Description: There are not enough studies to support the use of intracervical balloon catheter (IBC) use in term premature rupture

2017 Clinical Trials

172. Cervix Monitor for Elasticity and Length Measurements

learning disabilities, visual and hearing impairments. Spontaneous preterm delivery (SPTD) is often multi factorial event, precocious cervical softening, shortening and dilatation are a common denominator. The majority of preterm births happen spontaneously, though some are due to early induction of labor or cesarean birth, typically due to medical maternal of neonatal conditions. Condition or disease Intervention/treatment Preterm Birth Device: Cervix Monitor Detailed Description: The uterine cervix (...) has to provide structural integrity and mechanical resistance to ensure normal development of the fetus as the uterus expands to accommodate the fetus growth. Preterm delivery is closely related to a premature cervical ripening. The scientific bases for the proposed project is the elasticity modulus of a cervix is a more sensitive parameter characterizing the stage of cervical ripening. The main component of the cervix tissue is a collagen. Cervical ripening is the result of realignment

2017 Clinical Trials

173. Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions

rate of elimination of the infection. Immediate, an agent that stimulates like dendritic cells to producer cytokines and activates epithelial T cells. Imiquimode, when used in vulvar neoplasias, has been shown to be effective, presenting satisfactory results without treatment of CIN 2/3 of the uterine cervix, requiring a better scientific compilation. Based on these data, this study aims to evaluate the efficacy of topical immunomodulatory treatment for high-grade cervical intraepithelial lesions (...) previous treatment, who will be selected in the preventive clinic of the Hospital de Cancer de Barretos-SP (HCB ). Eligible patients will be identified at the return visit, when they will come to the hospital to check the result of the examination. In this study the patients will be randomized into two groups: Group 1: Control, where standard treatment will be offered, which is the conization of the uterine cervix with loop electrosurgical excision procedure(LEEP); Group 2: experimental group, which

2017 Clinical Trials

174. Preterm Induction of Labor: Predictors of Vaginal Delivery and Labor Curves. Full Text available with Trip Pro

divided into 4 groups based on gestational age (GA): group A, 24-27+6 weeks; B, 28-30+6 weeks; C, 31-33+6 weeks; and D, 34-36+6 weeks. Pregnant women with a contraindication to VD, IOL ≥37 weeks of gestation, and without data from cervical examination on admission were excluded. Analysis of variance was used to assess differences between GA groups. Multiple logistic regression was used to assess predictors of VD. A repeated measures analysis was used to determine average labor curves.Rates of vaginal (...) live births increased with GA, from 35% (group A) to 76% (group D). Parous women (odds ratio, 6.78; 95% confidence interval, 6.38-7.21) and those with a favorable cervix at the start of IOL (odds ratio, 2.35; 95% confidence interval, 2.23-2.48) were more likely to deliver vaginally. Analysis of labor curves in nulliparous women showed shorter duration of labor with increasing GA; the active phase of labor was, however, similar across all GAs.Most women who undergo medically indicated preterm IOL

2014 American Journal of Obstetrics and Gynecology

175. Cervical Cerclage for Preventing Spontaneous Preterm Birth in Singleton Pregnancies Without Prior Spontaneous Preterm Birth and With Short Transvaginal Ultrasound Cervical Length

Volunteers: No Criteria Inclusion Criteria: 18-50 ages Singleton pregnancy Cervical length <=25mm between 18(0) and 23(6) weeks Exclusion Criteria: Multiple pregnancy Prior spontaneous preterm birth or second trimester losses between 16(0) and 36(6) weeks Cerclage in situ Painful regular uterine contraction and/or preterm labor Ruptured membranes Major fetal defects Active vaginal bleeding Placenda previa and/or accreta Cervical dilation >1.5 cm and/or visible membranes by pelvic exam Suspicion (...) setting, and it is easily removed when necessary. However, a recent systematic review and meta-analysis of randomized clinical trials showed that in singleton pregnancies with short cervix, prophylactic use of the pessary did not reduce the rate of spontaneous preterm delivery or improve perinatal outcome. The evidence supports the use of vaginal progesterone in singleton pregnancies with short cervix, while cervical cerclage seems to be beneficial only in the subgroup of women with both prior SPTB

2016 Clinical Trials

176. Labor induction abortion in the second trimester

misoprostol alone. 7. Does the use of osmotic dilators affect the abortion time? Labor induction abortion studies using natural prosta- glandins found that placing osmotic dilators 4–24 h before inductiondecreasedabortiontime[30,83–88].However,this adjunctive benefit does not occur when modern prostaglan- din analogues are used. Two randomized studies examined the use of cervical preparation with laminaria at the time of misoprostol induction [2,15]. One study used feticide with hypertonic saline prior (...) rate of incomplete abortion and operative procedures as com- pared to pregnancies greater than 20 weeks. Unlike most other studies, these authors had follow-up data through 6 weeks postinduction. 2. How does labor induction abortion compare to surgical abortion? Where both methods are available, the choice between induction and D&E may be made for either personal or medical reasons. In some instances, the woman may wish to see or hold her fetus. Examination of an intact fetus may improve

2011 Society of Family Planning

177. Cervical Pessary vs Vaginal Progesterone in Preventing Preterm Birth Among Women Presenting With Short Cervix: An Open-label Randomized Controlled Trial

vaginal progesterone is superior to vaginal progesterone alone in decreasing preterm delivery rate, and improving perinatal outcome, among women presenting with an asymptomatic mid-pregnancy short cervix, in singleton and twin gestations. All women with singleton or twin pregnancies undergoing routine ultrasonography up to 24 completed weeks of gestation (for examination of fetal anatomy and growth) and diagnosed with cervical length of ≤25 mm in singleton, or ≤38 mm in twins, will be invited (...) Cervical Pessary vs Vaginal Progesterone in Preventing Preterm Birth Among Women Presenting With Short Cervix: An Open-label Randomized Controlled Trial Cervical Pessary vs Vaginal Progesterone in Preventing Preterm Birth Among Women Presenting With Short Cervix: An Open-label Randomized Controlled Trial - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail

2015 Clinical Trials

178. Mechanical and Pharmacologic Methods of Labor Induction: A Randomized Controlled Trial. Full Text available with Trip Pro

Mechanical and Pharmacologic Methods of Labor Induction: A Randomized Controlled Trial. To evaluate the effectiveness of four commonly used induction methods.This randomized trial compared four induction methods: misoprostol alone, Foley alone, misoprostol-cervical Foley concurrently, and Foley-oxytocin concurrently. Women undergoing labor induction with full-term (37 weeks of gestation or greater), singleton, vertex-presenting gestations, with no contraindication to vaginal delivery, intact (...) membranes, Bishop score 6 or less, and cervical dilation 2 cm or less were included. Women were enrolled only once during the study period. Our primary outcome was time to delivery. Neither patients nor health care providers were blinded to assigned treatment group because examinations are required for placement of all methods; however, research personnel were blinded during data abstraction. A sample size of 123 per group (n=492) was planned to compare the four groups pairwise (P≤.008) with a 4-hour

2016 Obstetrics and Gynecology Controlled trial quality: predicted high

179. Association of Early Amniotomy After Foley Balloon Catheter Ripening and Duration of Nulliparous Labor Induction. (Abstract)

Association of Early Amniotomy After Foley Balloon Catheter Ripening and Duration of Nulliparous Labor Induction. To evaluate the association between early amniotomy after ripening with a Foley balloon catheter and duration of labor induction.In this retrospective matched cohort study, 546 nulliparous women with a singleton viable gestation undergoing cervical ripening with a Foley balloon catheter were compared based on timing of amniotomy after catheter removal: early (defined as artificial (...) rupture of membranes less than 1 hour after Foley removal) compared with no artificial rupture of membranes in the first hour. Women in the early amniotomy group were matched to women in the control group according to health care provider type, cervical examination after Foley removal, and indication for induction in a one-to-one ratio. Bivariable and multivariable analyses were performed to determine whether early amniotomy was associated with vaginal delivery within 24 hours and other adverse

2016 Obstetrics and Gynecology

180. Prediction of delivery time in the second stage of labor using transperineal ultrasound. Full Text available with Trip Pro

Prediction of delivery time in the second stage of labor using transperineal ultrasound. To investigate whether the transperineal sonographic (TPS) parameters angle of progression (AoP) and midline angle (MLA) can predict the time remaining in the second stage of labor.We evaluated prospectively women with a singleton pregnancy in cephalic presentation at term between October 2013 and September 2014. TPS volumes were obtained immediately after confirmation by digital vaginal examination (...) of a fully dilated cervix. AoP and MLA were measured offline by analyzing the ultrasound volumes. Progression of labor was evaluated every hour during the second stage. The associations of AoP and MLA with the interval between TPS assessment and delivery were evaluated using multivariable Cox proportional hazards analyses in nulliparous and parous women separately.A total of 557 women were evaluated. An AoP ≥ 160° (adjusted hazard ratio (aHR), 2.52 (95% CI, 1.98-3.19)) and MLA ≤ 10° (aHR, 1.79 (95% CI

2016 Ultrasound in Obstetrics and Gynecology

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