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Cervical Examination in Labor

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121. Cervical Cancer Prevention (PDQ®): Health Professional Version

to environmental smoking.[ ] Case-control studies of women infected with HPV have examined the effect of various types and levels of tobacco exposure and found similar results.[ - ] DES exposure Diethylstilbestrol (DES) is a synthetic form of estrogen that was prescribed to pregnant women in the United States between 1940 and 1971 to prevent miscarriage and premature labor. DES is associated with a substantially increased risk of developing clear cell adenocarcinoma of the vagina and cervix among the daughters (...) Cervical Cancer Prevention (PDQ®): Health Professional Version Cervical Cancer Prevention (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet]. Bethesda (MD

2015 PDQ - NCI's Comprehensive Cancer Database

122. Concurrent Oxytocin With Membrane Sweeping Versus Dinoprostone Pessary in Labor Induction of Multiparous Women at Term

Resource links provided by the National Library of Medicine available for: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Oxytocin & Membrane sweeping Women assigned to "Concurrent oxytocin with membrane sweeping" had their cervix swept by inserting the examining finger as high as possible past the internal cervical os, followed by oxytocin infusion the next day Drug: Oxytocin Procedure: Membrane sweeping Active Comparator: Oxytocin & Dinoprostone Women assigned (...) is defined as vaginal delivery after 24 hours of initiating intervention (i.e. membrane sweeping or dinoprostone) on the first day of induction. Secondary Outcome Measures : Successful labor induction [ Time Frame: From the time of initiating intervention (i.e. membrane sweeping or dinoprostone) until the time of active phase of labor (defined as a cervical dilatation of >=4cm), assessed up to 24 hours ] to achieve the active phase of labor corresponding to a cervical dilatation of >=4cm Incidence

2015 Clinical Trials

123. Group B Streptococcus (GBS) Infection and in Preterm Labor Women Conceived Through IVF

ART, with signs and symptoms of preterm labor will be recruited. Anal - vaginal fluid samples will be taken by 2 cotton swabs from each participant for culture. Digital examination will be performed after that. Only participants fulfilling all the study's eligible criteria will be interviewed face-to-face with a questionnaire. The samples will be sent immediately to My Duc hospital laboratory or will be stored in Stuart-Amies medium in < 4 hours. All culture results are interpreted based (...) seconds) 20 0/7 to 36 6/7 weeks of gestation Intact membrane Cervical dilation ≤ 3 cm Willing to participate into the study Exclusion Criteria: To be eligible for enrolment in this study each subject must not meet any of the following criteria: Having had intercourse during 24 hours before Being suspected of amniotic leakage Rupture of membrane identified by direct observation through speculum examination of amniotic fluid flow from cervix Vaginal bleeding Being suspected of placenta abruption

2015 Clinical Trials

124. Concurrent Oxytocin With Membrane Sweeping Versus Dinoprostone Pessary in Labor Induction of Nulliparas at Term

Induction of Nulliparas at Term Study Start Date : April 2015 Estimated Primary Completion Date : December 2017 Estimated Study Completion Date : July 2018 Resource links provided by the National Library of Medicine available for: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Oxytocin & Membrane sweeping Women assigned to "Concurrent oxytocin with membrane sweeping" had their cervix swept by inserting the examining finger as high as possible past the internal cervical os (...) with dinoprostone or only dinoprostone) until the time of active phase of labor ( defined as a cervical dilatation of >=4cm), assessed up to 24 hours ] to achieve the active phase of labor corresponding to a cervical dilatation of >=4cm Incidence of cesarean delivery [ Time Frame: End of labor induction (assessed up to 120 hours) ] From the time of initiating intervention (i.e.concurrent membrane sweeping with dinoprostone or only dinoprostone) until the time of cesarean delivery, assessed up to 120 hours

2015 Clinical Trials

125. Comparison of Low-dose and High-dose Oxytocin Regimens for Labor Augmentation

, 2018 See Sponsor: Northwestern University Information provided by (Responsible Party): Moeun Son, Northwestern University Study Details Study Description Go to Brief Summary: Oxytocin is a medication that is often used to strengthen contractions to overcome delayed labor progress. The primary aim of this study is to determine whether receiving a higher dose of oxytocin lowers the chance of needing a cesarean section when compared to a lower dose of oxytocin. Other aims include examining (...) contractions have failed to result in progressive cervical dilation of descent of fetus. Exclusion Criteria: Women not meeting the above criteria History of prior cesarean section or uterine surgery Fetus in non-cephalic presentation Participant is undergoing labor induction (i.e. cervical ripening) Non-English speaking Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact

2015 Clinical Trials

126. Assessing First Stage Labor Progression and Its Relationship to Complications. (PubMed)

, based in part on these findings, are applicable only in late labor. The wide range of time to dilate is unavoidable because cervical dilation has neither a precise nor direct relationship to time. Newer statistical techniques (multifactorial models) can improve precision by incorporating several factors that are related directly to labor progress. At each examination, the calculations adapt to the mother's current labor conditions. They produce a quantitative assessment that is expressed (...) monitoring and cord gases at 2 academic community referral hospitals in 2012 and 2013. We assessed electronic data for route of delivery, all dilation and station examinations, newborn infant status, electronic fetal monitoring tracings, and cord blood gases. The labor-related complication groups included 272 women with cesarean delivery for first-stage arrest, 558 with cesarean delivery for fetal heart rate concerns, 178 with obstetric hemorrhage, and 237 with neonatal depression, which left 3004 women

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2015 American Journal of Obstetrics and Gynecology

127. Sonographically accessed funneling of the uterine cervix as a predictor of successful labor induction (PubMed)

delivered a baby by labor induction were enrolled in the study from July 2011 to August 2013. Cervical funneling and length were examined with transvaginal ultrasonography. The Bishop score was rated by digital pelvic examination.A total of 163 primigravida women were recruited for the study. Of these, 137 participants (84.0%) delivered vaginally by labor induction. Cervical funneling was observed in 93 women (57.1%). Successful labor induction was significantly higher in patients with cervical (...) Sonographically accessed funneling of the uterine cervix as a predictor of successful labor induction The Bishop score and length of the uterine cervix are good predictors of successful labor induction. However, little is known about the association between the funneling of the uterine cervix and successful labor induction. The study aimed to evaluate cervical funneling as a predictor of successful labor induction.This study was designed as a prospective observational study. Subjects who

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2015 Obstetrics & gynecology science

128. Practice patterns in the management of threatened preterm labor in Korea: A multicenter retrospective study (PubMed)

Practice patterns in the management of threatened preterm labor in Korea: A multicenter retrospective study This study aimed to examine clinical practice patterns in the management of pregnant women admitted with threatened preterm labor (TPL) in Korea.Data from women admitted with a diagnosis of TPL were collected from 22 hospitals. TPL was defined as regular uterine contractions with or without other symptoms such as pelvic pressure, backache, increased vaginal discharge, menstrual-like (...) cramps, bleeding/show and cervical changes. Data on general patient information, clinical characteristics at admission, use of tocolytics, antibiotics, and corticosteroids, and pregnancy outcomes were collected using an online data collections system.A total of 947 women with TPL were enrolled. First-line tocolysis was administered to 822 (86.8%) patients. As a first-line tocolysis, beta-agonists were used most frequently (510/822, 62.0%), followed by magnesium sulfate (183/822, 22.3%), calcium

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2015 Obstetrics & gynecology science

129. Transperineal ultrasonography for labor management: accuracy and reliability. (PubMed)

Transperineal ultrasonography for labor management: accuracy and reliability. To compare ultrasound measurements and clinical assessments of cervical dilatation, fetal head station and fetal head position.Prospective, observational study.Tertiary care center (Ankara University Hospital), labor ward.Forty-three women in labor.Women were prospectively evaluated through simultaneous examinations (79 in total). Dilatation, head station, and position were recorded via digital examination whenever (...) a mean lower cervical dilatation of 10 mm (95% limits of agreement: -36 to 16 mm) compared with digital examination. The angle of progression and head-perineum distances correlated moderately with the palpated head station (Pearson's correlation coefficients: 0.55 and -0.42, respectively; p < 0.001). Position could only be assessed in 40 of 79 examinations by digital examinations and the results showed low agreement with ultrasound findings.We observed good agreement between clinical and ultrasound

2015 Acta Obstetricia et Gynecologica Scandinavica

130. A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor

on a verbal history from the subject with the intent of getting confirmation from the medical records as soon as possible. Females must be diagnosed with preterm labor according to both of the following criteria: a) Regular uterine contractions at a rate of >=4 contractions of at least 30 seconds' duration during a 30-minute interval confirmed by tocodynamometry and at least 1 of the following, b) Cervical dilation >=2 centimeter (cm) and <=4 cm by digital cervical examination or c) If <2 cm dilation (...) by digital cervical examination, a cervical change consisting of an increase of at least 25% effacement or 1-cm dilation. Current or past tocolytic treatment as follows: a) Subjects in whom tocolytic treatment has not been initiated prior to consent are eligible for the study, b) Transferred or referred subjects for whom parenteral magnesium sulfate treatment has been started before Screening are eligible provided they meet all eligibility criteria, c) Subjects receiving a prohibited tocolytic

2015 Clinical Trials

131. Analysis of Contemporary Labor Patterns Measured Via Transperineal Ultrasonography

Not Applicable Detailed Description: Intrapartum sonography is rapidly advancing field in the management of obstetrics labor. Traditional approach to labor management consists evaluation of cervical dilatation, head position and head descent via digital examinations. Rate of progress is evaluated using data of available labor curves. Unsatisfactory progression is either treated with labor augmentation or cesarean section depending on the degree and duration of labor retardation. Transperineal ultrasonography (...) transperineal ultrasonography. Factors which are known to effect duration of labor will be taken into account. Condition or disease Intervention/treatment Phase Pregnancy Obstetric Labor Device: Transperineal ultrasonography, General Electric Healthcare Voluson Ultrasound System Device: Cardiotocography, Bionet FC1400 Fetal Monitor Other: Amniotomy Drug: Analgesics, Opioid, Meperidine Drug: Labor augmentation, Oxytocin Drug: Labor induction, Oxytocin Drug: Cervical ripening, labor induction, Dinoprostone

2015 Clinical Trials

132. Predictive Factors for Delivery within 7 Days after Successful 48-Hour Treatment of Threatened Preterm Labor. (PubMed)

Predictive Factors for Delivery within 7 Days after Successful 48-Hour Treatment of Threatened Preterm Labor. Objective The aim of this study was to assess which characteristics and results of vaginal examination are predictive for delivery within 7 days, in women with threatened preterm labor after initial treatment. Study Design A secondary analysis of a randomized controlled trial on maintenance nifedipine includes women who remained undelivered after threatened preterm labor for 48 hours (...) . We developed one model for women with premature prelabor rupture of membranes (PPROM) and one without PPROM. The predictors were identified by backward selection. We assessed calibration and discrimination and used bootstrapping techniques to correct for potential overfitting. Results For women with PPROM (model 1), nulliparity, history of preterm birth, and vaginal bleeding were included in the multivariable analysis. For women without PPROM (model 2), maternal age, vaginal bleeding, cervical

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2015 AJP Reports Controlled trial quality: predicted high

133. Does a cervical membrane sweep in a term healthy pregnancy reduce the length of gestation?

. The reference list of a relevant Cochrane review was handsearched to locate further studies. Study selection Eligible studies were randomised controlled trials (RCTs) that examined the effectiveness of one cervical membrane sweep in single healthy term pregnancies (37 to 42 weeks of gestation) with a cephalic presentation for both nulliparous and multiparous women. To be included, trials had to describe the method of the sweep. The primary outcome was the time interval between randomisation and birth (...) of pregnancy, and should be made aware of the risks associated with prolonged pregnancy and induction of labour. Research : The author stated that further research was needed to provide clear recommendations for practice; such research should include large sample sizes, subgroups of parity, and examination of the role of serial cervical membrane sweep. Funding Not stated. Bibliographic details Rogers H. Does a cervical membrane sweep in a term healthy pregnancy reduce the length of gestation? MIDIRS

2010 DARE.

134. The role of maternal attachment in the experience of labor pain: a prospective study. (PubMed)

The role of maternal attachment in the experience of labor pain: a prospective study. To examine the influence of attachment dimensions and sociodemographic and physical predictors in the experience of labor pain.Eighty-one pregnant women were assessed during their third trimester of pregnancy and during labor. The perceived intensity of pain in the early stages of labor (3 cm of cervical dilatation) and before the administration of patient-controlled epidural analgesia was measured using (...) a visual analog scale. Pain was also assessed indirectly based on anesthetic doses. Attachment was assessed using the Adult Attachment Scale-Revised.Attachment anxiety and avoidance were positively and significantly correlated with labor pain and anesthetic consumption. In the multivariate models, attachment anxiety was a significant predictor of higher pain at 3 cm of cervical dilatation (β = 0.36, p = .042) and before the administration of patient-controlled epidural analgesia (β = 0.51, p = .002

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2014 Psychosomatic Medicine

135. Fetal Descent in Labor. (PubMed)

, including cervical examinations, were collected. A repeated-measures analysis was used to construct average descent curves. Interval-censored regression was used to estimate duration of labor between levels of station and to estimate the median station at a given dilation. Each analysis was stratified by parity and labor type (spontaneous compared with induced or augmented).Of 4,618 consecutive-term spontaneous vaginal deliveries, 1,526 (33%) were nulliparous. Sixty-one percent were augmented or induced (...) Fetal Descent in Labor. Studies using contemporary populations and modern statistical methods have redefined our understanding of cervical dilation in labor. However, modern norms for fetal descent in labor have not been developed. We sought to estimate norms for fetal descent and estimate the expected fetal station for given cervical dilations.A retrospective cohort study of consecutive-term, vertex singletons who delivered vaginally. Detailed history, labor, and delivery information

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2014 Obstetrics and Gynecology

136. A Prospective Observational Study of Ethnic and Racial Differences in Neuraxial Labor Analgesia Request and Pain Relief. (PubMed)

enrolled in this prospective observational cohort study. Term laboring parturients who planned vaginal delivery and requested neuraxial labor analgesia were eligible for inclusion. Data collected included cervical dilation at the time of neuraxial analgesia request, self-identified ethnicity/race, parity, education, insurance status, pain score before and after the initiation of neuraxial analgesia, and mode of delivery. The primary outcome was cervical dilation at the time of neuraxial analgesia (...) request. Ethnicity/race classification was determined by asking the patient, "How would you define your ethnicity?" Patients were categorized into the ethnic/racial groups of non-Hispanic White, African American, Hispanic, or other. Univariate associations between cervical dilation and categorical variables were examined. Multivariate analysis was performed for the primary outcome of cervical dilation at the time of initiation of neuraxial analgesia.At the time of neuraxial analgesia placement

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2014 Anesthesia and Analgesia

137. Changes in Shear Wave Speed Pre and Post Induction of Labor: a Feasibility Study. (PubMed)

Changes in Shear Wave Speed Pre and Post Induction of Labor: a Feasibility Study. To explore the feasibility of using shear wave speed (SWS) estimates to detect differences in cervical softening pre- and post-ripening in women undergoing induction of labor.Subjects at 37-41 weeks' gestation undergoing cervical ripening before induction of labor were recruited (n = 20). Examinations, performed prior to administration of misoprostol and 4 h later included Bishop score, transvaginal ultrasound (...) measurement of cervical length, and 10 replicate SWS measurements using an ultrasound system equipped with a prototype transducer (128 element, 3 mm diameter, 14 mm aperture) attached to the clinician's hand. Subjects were divided into two groups, 'not-in-labor' and 'marked-progression', based on cervical evaluation at the second examination. Measurements were compared via individual paired hypotheses tests and using a linear mixed model, with the latter also used to compare groups. Spearman's rank

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2014 Ultrasound in Obstetrics and Gynecology

138. Medical Transfer of Patients in Preterm Labor: Treatments and Tocolytics. (PubMed)

Medical Transfer of Patients in Preterm Labor: Treatments and Tocolytics. Abstract Objective. To examine the epidemiology, effectiveness, and safety of tocolytics, and the variation in use of standard treatments and predictive testing for women in preterm labor (PTL) transported to tertiary care. Methods. This was a health record review of consecutive PTL patients (<38 weeks gestation) transported to a tertiary care facility by Ontario's air and land critical care transport service between (...) January 1, 2006 and January 1, 2011. The primary outcome was the effectiveness of tocolytics in decreasing the frequency of contractions and incidence of delivery. Secondary outcomes included the type of tocolytics used, adverse events (defined a priori), use of standard treatments (corticosteroid, antibiotic), and use of predictive tests (cervical length measurement, fetal fibronectin). We report descriptive statistics and relative risk of contractions decreasing with tocolytics with 95% confidence

2014 Prehospital emergency care

139. Management of Acute Preterm Labor: Nifedipen Alone or Combined With Cildenafil Citrate

enrolled the participants. Each patient will undergo an ultrasound examination prior to randomization to confirm GA, rule out major fetal anomalies and to determine cervical measurements. Dexamethasone in a total dose of 24 mg will be administered to all patients if not given in a previous admission. Eligible women are then randomly assigned into two study groups: Group I: (combined nifedipine and sildenafil citrate) The protocol for nifedipen in our units consists of 20 mg orally stat, followed by 10 (...) Management of Acute Preterm Labor: Nifedipen Alone or Combined With Cildenafil Citrate Management of Acute Preterm Labor: Nifedipen Alone or Combined With Cildenafil Citrate - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2014 Clinical Trials

140. Optimizing Management of the 2nd Stage of Labor: Multicenter Randomized Trial

.) First Posted : May 13, 2014 Last Update Posted : March 14, 2018 Sponsor: Washington University School of Medicine Collaborator: National Institutes of Health (NIH) Information provided by (Responsible Party): Methodius Tuuli, MD, MPH, Washington University School of Medicine Study Details Study Description Go to Brief Summary: The investigators propose a large, multicenter, randomized clinical trial of immediate versus delayed pushing for nulliparous women in labor at term reaching complete cervical (...) dilation. The central hypothesis is that immediate pushing in the second stage of labor increases spontaneous vaginal delivery, shortens duration of the second stage, and reduces adverse neonatal and maternal outcomes in nulliparous women. They will pursue the following specific aims: 1) Assess the effectiveness of immediate pushing at complete cervical dilation on the rate of spontaneous vaginal delivery in nulliparous women (Primary Aim), 2) Determine the effect of immediate pushing on the rate

2014 Clinical Trials

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