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Cervical Spondylotic Myelopathy

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1. Analysis of sagittal alignment parameters following anterior cervical hybrid decompression and fusion of multilevel cervical Spondylotic myelopathy. (PubMed)

Analysis of sagittal alignment parameters following anterior cervical hybrid decompression and fusion of multilevel cervical Spondylotic myelopathy. To investigate the relationships between sagittal parameters and health-related quality of life (HRQOL) scores following anterior cervical hybrid decompression and fusion (ACHDF) of multilevel cervical spondylotic myelopathy (CSM) and to study the impact of the T1 slope (T1 s).In total, 42 patients with complete radiographic measurements following (...) ACHDF in the Spine Surgery Department of the First Affiliated Hospital of Fujian Medical University from August 2014 to January 2017 were retrospectively analysed. Radiographic measurements included C2-7 lordosis, T1 s, C2-7 sagittal vertical axis (SVA), cervical tilting and cranial tilting. The neck disability index (NDI) was used to evaluate the HRQOL. Spearman's correlation coefficients were calculated between pairs of cervical sagittal parameters and NDI scores.Preoperative NDI scores were

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2019 BMC Musculoskeletal Disorders

2. Dynamic MRI to Diagnose Spinal Canal Stenosis not Visualized on Standard Static MRI in patients with Cervical Spondylotic Myelopathy

Dynamic MRI to Diagnose Spinal Canal Stenosis not Visualized on Standard Static MRI in patients with Cervical Spondylotic Myelopathy "Dynamic MRI to Diagnose Spinal Canal Stenosis not Visualized on Standa" by Gabrielle L. Engelhard < > > > > > Title Author Date of Graduation Summer 8-13-2016 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Mark Pedemonte, MD Rights . Abstract Background: Cervical Spondylotic Myelopathy (CSM) is a common (...) articles of which only two studies met inclusion criteria. The results from both the Zeituon et al and Harada et al studies demonstrate that dynamic MRI in the preoperative evaluation of Cervical Spondylotic Myelopathy visualizes more levels of spinal cord compression than neutral position MRI alone. The Zeituon et al showed that stages of canal stenosis were found to be higher in extension than when compared to flexion or neutral position, and also that hyperintense intramedullary lesions (HILs

2016 Pacific University EBM Capstone Project

3. What is the best surgical option for two-level cervical spondylotic myelopathy: a network meta-analysis

What is the best surgical option for two-level cervical spondylotic myelopathy: a network meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files

2019 PROSPERO

4. Preoperative cervical sagittal alignment parameters and their impacts on myelopathy in patients with cervical spondylotic myelopathy: a retrospective study (PubMed)

Preoperative cervical sagittal alignment parameters and their impacts on myelopathy in patients with cervical spondylotic myelopathy: a retrospective study Cervical sagittal alignment plays an important role in the pathogenesis of cervical spondylotic myelopathy (CSM), but there are limited studies on the cervical sagittal parameters in CSM patients and their correlations with myelopathy. The aim of this study is to investigate the correlations among the preoperative cervical sagittal alignment (...) parameters and their correlations with the development of myelopathy in patients with CSM.We retrospectively collected 212 patients with CSM who underwent surgical interventions. Gender, age, modified Japanese Orthopedic Association score (mJOA), cervical lordosis (CL), C2-C7 sagittal vertical axis (C2-C7 SVA), T1 slope (T1S), neck tilt (NT) and thoracic inlet angle (TIA) were collected before operation. Interobserver and intraobserver reliability were calculated for all measurements (intraclass

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2017 PeerJ

5. Prospective Comparison of Age- and Sex-Related Differences in Quantifiable 10-S Grip and Release and 10-S Step Test Results for Diagnosis of Cervical Spondylotic Myelopathy in 454 Patients with Cervical Spondylotic Myelopathy and 818 Asymptomatic Subjects (PubMed)

Prospective Comparison of Age- and Sex-Related Differences in Quantifiable 10-S Grip and Release and 10-S Step Test Results for Diagnosis of Cervical Spondylotic Myelopathy in 454 Patients with Cervical Spondylotic Myelopathy and 818 Asymptomatic Subjects A prospective comparison.The purpose of this prospective study was to verify the clinical effectiveness of the 10-s grip and release (G&R) and 10-s step quantitative tests for assessing the severity of cervical spondylotic myelopathy (CSM (...) according to their age by decade. The 10-s G&R and 10-s step tests were used to quantitatively assess performance. The severity of myelopathy before surgery was evaluated according to a scoring system proposed by the Japanese Orthopaedic Association for cervical myelopathy (JOA score) in the CSM patients.In the CSM patients, the 10-s G&R and step test results significantly correlated with the JOA score (P < 0.0001). The number of the 10-s G&R and step tests significantly decreased with age in both

2016 Spine

6. Risk Factors for Rapidly Progressive Neurological Deterioration in Cervical Spondylotic Myelopathy. (PubMed)

Risk Factors for Rapidly Progressive Neurological Deterioration in Cervical Spondylotic Myelopathy. A retrospective single-center study.This study sought to clarify the risk factors and to evaluate the surgical outcome in patients with rapidly progressive cervical spondylotic myelopathy (rp-CSM).CSM is a degenerative spine disease presenting a slow development of myelopathy. However, some patients show rapidly progressive neurological deterioration (especially gait disturbances) without any (...) trauma. At present, there is little information about this condition.We studied 71 consecutive CSM-patients (52 males, 19 females) with a mean age of 67.1 years, and the follow-up period was 1 year. Patients were divided into two groups: rp-CSM and chronic-CSM (c-CSM) groups. The JOA score and various clinical differences, including age, sex, comorbidity, the waiting period from symptomatic onset to surgery, cervical range of motion (ROM), and intramedullary MR T2-highperintensity were analyzed

2019 Spine

7. 30-Day unplanned surgery in cervical spondylotic myelopathy surgically treated: a single-center experience. (PubMed)

30-Day unplanned surgery in cervical spondylotic myelopathy surgically treated: a single-center experience. Retrospective cohort study.Analyze the rate and risk factors associated with Unplanned Surgeries (US) during the first 30 days in patients treated for cervical spondylotic myelopathy.US are often regarded as a potentially useful quality of care indicator.We defined US as any, non-planned, surgical procedure as a complication after "index" surgery. Demographic data, comorbidities, ASA

2019 European Spine Journal

8. Comparison of clinical outcomes and safety between laminectomy with instrumented fusion versus laminoplasty for the treatment of multilevel cervical spondylotic myelopathy. (PubMed)

Comparison of clinical outcomes and safety between laminectomy with instrumented fusion versus laminoplasty for the treatment of multilevel cervical spondylotic myelopathy. Systematic review and meta-analysis.Posterior laminectomy with instrumented fusion and laminoplasty are widely used for the treatment of multilevel cervical spondylotic myelopathy (MCSM). There is great controversy over the preferred surgical method. The purpose of this study is to evaluate the clinical outcomes and safety (...) ) scores, preoperative and postoperative visual analog scale (VAS), preoperative and postoperative cervical range of motion (ROM), preoperative and postoperative cervical curvature index (CCI), overall complication rate, C5 nerve palsy rate, axial symptoms rate, operation time and blood loss.A total of 15 studies were included in this meta-analysis. All of the selected studies were of high quality as indicated by the Newcastle-Ottawa scale (NOS). Among 1131 patients, 555 underwent laminectomy

2019 Medicine

9. Effects of decompressive operation on cardiac autonomic regulation in patients with cervical spondylotic myelopathy: analysis of blood pressure, heart rate, and heart rate variability. (PubMed)

Effects of decompressive operation on cardiac autonomic regulation in patients with cervical spondylotic myelopathy: analysis of blood pressure, heart rate, and heart rate variability. To investigate the effects of cervical decompression operation on cardiac autonomic regulation and its relationship to recovery of somatic neurological function in cervical spondylotic myelopathy (CSM) patients.One hundred and thirty-two consecutive patients were enrolled in this study, in which 73 patients

2019 European Spine Journal

10. Comparison of laminectomy and fusion vs laminoplasty in the treatment of multilevel cervical spondylotic myelopathy: A meta-analysis. (PubMed)

Comparison of laminectomy and fusion vs laminoplasty in the treatment of multilevel cervical spondylotic myelopathy: A meta-analysis. The purpose of this study is to evaluate the clinical safety and efficacy between laminectomy and fusion (LF) versus laminoplasty (LP) for the treatment of multi-level cervical spondylotic myelopathy (CSM).The authors searched electronic databases using PubMed, MEDLINE, Embase, Cochrane Controlled Trial Register, and Google Scholar for relevant studies (...) that compared the clinical effectiveness of LF and LP for the treatment of patients with multilevel CSM. The following outcome measures were extracted: the Japanese Orthopaedic Association (JOA) scores, cervical curvature index (CCI), visual analog scale (VAS), Nurich grade, reoperation rate, complications, rate of nerve palsies. Newcastle Ottawa Quality Assessment Scale (NOQAS) was used to evaluate the quality of each study. Data analysis was conducted with RevMan 5.3.A total of 14 studies were included

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2019 Medicine

11. Postoperative Resolution of MR T2 Increased Signal Intensity in Cervical Spondylotic Myelopathy: The Impact of Signal Change Resolution on the Outcomes. (PubMed)

Postoperative Resolution of MR T2 Increased Signal Intensity in Cervical Spondylotic Myelopathy: The Impact of Signal Change Resolution on the Outcomes. Prospective comparative imaging study.This study investigated whether postoperative resolution of spinal cord increased signal intensity (ISI) reflected symptom improvement and surgical outcomes in cervical spondylotic myelopathy (CSM) patients.Although some CSM patients exhibit magnetic resonance imaging (MRI) ISI, its alteration (...) resonance images into: Grade 0, none; Grade 1, light (obscure); and Grade 2, intense (bright). The patients' pre- and postoperative neurological statuses were evaluated using the Japanese Orthopedic Association scoring system for cervical myelopathy (JOA score) and other quantifiable tests, including the 10-s grip and release (10-s G&R) test and 10-s step test.A total of 337 patients showed preoperative ISI. Among these, 42 (12.5%) showed postoperative ISI resolution, associated with better

2019 Spine

12. Clinical and Radiographic Outcome of Patients with Cervical Spondylotic Myelopathy Undergoing Total Disc Replacement. (PubMed)

Clinical and Radiographic Outcome of Patients with Cervical Spondylotic Myelopathy Undergoing Total Disc Replacement. MINI: Cervical total disc replacement (with ProDisc Vivio) in patients with CSM yielded good clinical (NDI, VAS, JOA scores, Nurick grades) and radiographic outcomes and was found a reliable, safe and motion preserving surgical treatment option, although its indication is very limited due to numerous exclusion criterias.Non-randomized prospective and single center clinical (...) trial.Investigate the clinical and radiographic efficacy of ProDisc Vivo cervical total disc replacement (cTDR) in patients with clinical and radiographic documented cervical spondylotic myelopathy (CSM), due to degenerative changes at the index level.Decompression and fusion is still the gold standard in patients with cervical myelopathy. Very limited data are available regarding the application of cTDR in patients with clinical and radiological documented CSM in context of clinical and radiographic

2019 Spine

13. Characterizing Gait Abnormalities in Patients with Cervical Spondylotic Myelopathy: A Neuromuscular Analysis. (PubMed)

Characterizing Gait Abnormalities in Patients with Cervical Spondylotic Myelopathy: A Neuromuscular Analysis. Gait impairment is a hallmark of cervical spondylotic myelopathy (CSM). It has been shown to affect quality of life but has not been well defined. Further electromyographic (EMG) characterization of the gait cycle may help elucidate the true neuromuscular pathology with implications on prognosis and rehabilitation techniques.This study compares neuromuscular activity in patients

2019 The Spine Journal

14. Comparison of clinical outcomes of expansive open-door laminoplasty with unilateral or bilateral fixation and fusion for treating cervical spondylotic myelopathy: a multi-center prospective study. (PubMed)

Comparison of clinical outcomes of expansive open-door laminoplasty with unilateral or bilateral fixation and fusion for treating cervical spondylotic myelopathy: a multi-center prospective study. The present study evaluated the clinical outcomes and safety of expansive open-door laminoplasty, when securing with C4 - C6 lateral mass screw and fusion.A total of 110 patients with cervical spondylotic myelopathy (CSM) were enrolled. There were 88 male and 22 female, with mean age at 60.55 ± 10.95 (...)  years. All of the patients underwent expansive open-door laminoplasty with unilateral or bilateral C4-6 lateral mass screws fixation and fusion. Clinical data, including age, gender, operation-related information, pre- and post-operation Japanese Orthopedic Association (JOA) scores, and cervical curvatures were collected.The mean follow-up time of the cohort was 13.61 ± 9.53 months. Among the 110 patients, 33 of them were allocated to Unilateral group, and 77 of them were in Bilateral group

2019 BMC Surgery

15. Functional Connectivity Changes of the Visual Cortex in the Cervical Spondylotic Myelopathy Patients: A Resting-State fMRI Study. (PubMed)

Functional Connectivity Changes of the Visual Cortex in the Cervical Spondylotic Myelopathy Patients: A Resting-State fMRI Study. : Study Design. Cross-sectional study.To analyze altered functional connectivity (FC)in the visual cortex of cervical spondylotic myelopathy (CSM) patients using resting-state fMRI.We previously showed changes in visual cortex neural activity in CSM patients.Thirty CSM patients and 20 healthy controls were recruited. MR data were collected using a 3.0 T MR. FC

2019 Spine

16. The Effect of an Educational and Interactive Informed Consent Process on Patients with Cervical Spondylotic Myelopathy Caused by Ossification of the Posterior Longitudinal Ligament. (PubMed)

The Effect of an Educational and Interactive Informed Consent Process on Patients with Cervical Spondylotic Myelopathy Caused by Ossification of the Posterior Longitudinal Ligament. Prospective observational cohort study OBJECTIVE.: In this study, an educational and interactive informed consent (EIC) program was proposed for patients with OPLL-CSM to improve their comprehension level during the informed consent process.Cervical spondylotic myelopathy caused by ossification of the posterior

2019 Spine

17. A Technique for Dynamic Cervical Magnetic Resonance Imaging Applied to Cervical Spondylotic Myelopathy: A Reliability Study. (PubMed)

A Technique for Dynamic Cervical Magnetic Resonance Imaging Applied to Cervical Spondylotic Myelopathy: A Reliability Study. Cross-sectional study.To evaluate morphometric variations of the cervical spine in patients with cervical spondylotic myelopathy (CSM) using a standard technique of dynamic magnetic resonance imaging (MRI), to assess the inter- and intraobserver reliability of measurements of morphometric parameters based on this imaging, and to compare the resulting measurements (...) with those previously published.Because dynamic factors may contribute to the etiology and severity of CSM, dynamic (flexion-extension) MRI may be useful to better evaluate for spinal stenosis and cord compromise.Dynamic cervical MRI was obtained using a standard protocol with the neck in neutral, flexion, and extension positions. The morphometric parameters considered were anterior length of the spinal cord (ALSC), posterior length of the spinal cord (PLSC), spinal canal diameter, and spinal cord width

2018 Spine

18. Short-term outcomes following posterior cervical fusion among octogenarians with cervical spondylotic myelopathy: a NSQIP database analysis. (PubMed)

Short-term outcomes following posterior cervical fusion among octogenarians with cervical spondylotic myelopathy: a NSQIP database analysis. Degenerative changes in the cervical spine occur in an age-dependent manner. As the US population continues to age, the incidence of age-dependent, multilevel, degenerative cervical pathologies is expected to increase. Similarly, the average age of patients with cervical spondylotic myelopathy (CSM) will likely trend upward. Posterior cervical fusion (PCF (...) ) is often the treatment modality of choice in the management of multilevel cervical spine disease. Although outcomes following anterior cervical fusion for degenerative disease have been studied among older patients (aged 80 years and older), it is unknown if these results extend to octogenarian patients undergoing PCF for the surgical management of CSM.The present study aimed to quantify surgical outcomes following PCF for the treatment of CSM among the octogenarian patient population compared

2018 The Spine Journal

19. Anterior corpectomy and reconstruction using dynamic cervical plate and titanium mesh cage for cervical spondylotic myelopathy: A minimum 5-year follow-up study. (PubMed)

Anterior corpectomy and reconstruction using dynamic cervical plate and titanium mesh cage for cervical spondylotic myelopathy: A minimum 5-year follow-up study. Anterior cervical corpectomy and fusion (ACCF) is an effective surgical technique for cervical spondylotic myelopathy (CSM). However, no data exist regarding long-term outcomes after ACCF with the dynamic cervical plate for CSM. This study aimed to provide minimum 5-year clinical and radiographic outcomes of anterior corpectomy (...) and reconstruction using dynamic cervical plate and titanium mesh cage (TMC) for CSM.Thirty-five patients who underwent single- or 2-level ACCF with dynamic cervical plate and TMC for the treatment of CSM were retrospectively investigated. The Japanese Orthopedic Association (JOA) score was used to assess the clinical outcome. Radiographic evaluations included TMC subsidence, fusion status, cervical lordosis, segmental angle, and segmental height.Twenty-eight patients underwent single-level and 7 patients

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2018 Medicine

20. Modic changes in the cervical endplate of patients suffering from cervical spondylotic myelopathy (PubMed)

Modic changes in the cervical endplate of patients suffering from cervical spondylotic myelopathy The distribution and related factors of Modic changes (MC) in the lumbar spine has been evaluated. In the present study, the MC in the cervical endplate of patients with cervical spondylotic myelopathy (CSM) was investigated.A total of 6422 cervical endplates of 539 patients suffered from CSM (259 males and 280 females) with mean age of 46 ± 5.2 years. All patients underwent MRI scans and X-ray

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2018 Journal of orthopaedic surgery and research

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