How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,586 results for

Cerebrovascular Accident Risk in Women

by
...
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

161. Colonoscopy Outcomes by Duration of NPO Status Prior to Colonoscopy with Moderate or Deep Sedation

SUMMARY Introduction 1 Methods 2 Data Sources and Searches 2 Study Selection 2 Data Abstraction and Risk of Bias Assessment 2 Data Synthesis and Analysis 2 Results 3 Results of Literature Search 3 Overview 3 Executive Summary Table 1. Summary of Outcomes Reported in Included Studies 3 Summary of Results for Key Questions 4 Discussion 6 Key Findings and Strength of Evidence 6 Applicability 7 Research Gaps/Future Research 7 Conclusions 7 Abbreviations Table 8 INTRODUCTION 9 METHODS Topic Development 11 (...) Search Strategy 11 Study Selection 11 Data Abstraction 11 Risk of Bias Assessment 12 Data Synthesis 12 Rating the Body of Evidence 12 Peer Review 12 ii NPO Status Prior to Colonoscopy Evidence-based Synthesis Program RESULTS Literature Flow 13 Overview 14 Key Question 1. Does the incidence of aspiration and other anesthesia-related harms for colonoscopy vary by NPO status or bowel prep timing (eg, > 6 hours, 2-6 hours, 6 hours, 2-6 hours, 6 hours, 2-6 hours, 6 hours, 2-6 hours, 8 hours indicates

2015 Veterans Affairs Evidence-based Synthesis Program Reports

162. Breast Cancer Treatment (PDQ®): Health Professional Version

. In the last decade, women have refrained from using postmenopausal hormones, and breast cancer incidence has declined, but not to the levels seen before the widespread use of screening mammography.[ ] Anatomy Anatomy of the female breast. The nipple and areola are shown on the outside of the breast. The lymph nodes, lobes, lobules, ducts, and other parts of the inside of the breast are also shown. Risk Factors Increasing age is the most important risk factor for most cancers. Other risk factors for breast (...) ).[ ] Personal history of breast cancer.[ ] Personal history of benign breast disease (BBD) (proliferative forms of BBD).[ - ] Radiation exposure to breast/chest. [ ] Age-specific risk estimates are available to help counsel and design screening strategies for women with a family history of breast cancer.[ , ] Of all women with breast cancer, 5% to 10% may have a germline mutation of the genes BRCA1 and BRCA2 .[ ] Specific mutations of BRCA1 and BRCA2 are more common in women of Jewish ancestry

2018 PDQ - NCI's Comprehensive Cancer Database

163. Acute pain management: scientific evidence (3rd Edition)

: Scientific Evidence xv CONTENTS 9. SPECIFIC CLINICAL SITUATIONS 237 9.1 Postoperative pain 237 9.1.1 Risks of acute postoperative neuropathic pain 237 9.1.2 Acute postamputation pain syndromes 238 9.1.3 Other postoperative pain syndromes 240 9.1.4 Day-stay or short-stay surgery 242 9.1.5 Cranial neurosurgery 245 9.2 Acute pain following spinal cord injury 247 9.3 Acute burn injury pain 249 9.3.1 Management of procedural pain 250 9.3.2 Non-pharmacological pain management 251 9.4 Acute back pain 252 9.5 (...) pain after surgery 11 1.3 Risk factors for chronic postsurgical pain 11 1.4 Definitions of pre-emptive and preventive analgesia 13 1.5 Summary of studies according to target agent administered 14 1.6 Metabolic and endocrine responses to injury 17 2.1 Fundamentals of a pain history 36 3.1 Possible benefits of an Acute Pain Service 51 4.1 Antidepressants for the treatment of neuropathic pain 89 6.1 The 2007 Oxford league table of analgesic efficacy 154 9.1 Taxonomy of acute pain associated

2015 National Health and Medical Research Council

164. Guidance on the clinical management of depressive and bipolar disorders, specifically focusing on diagnosis and treatment strategies

disorders, and the potential risk of further over pathologising healthy children. It is best seen as a category that enables further research on the natural history and best management of such presentations. g Premenstrual Dysphoric Disorder (PMDD) is also a new diagnosis used to describe women of menstruating age who experience severe dysphoria, irritability or mood swings in the week prior to the onset of menses and finishing a few days after the onset of menses. These symptoms need (...) Disorders Clinical Practice Guideline (Mood Disorders CPG) has been developed by the Royal Australian and New Zealand College of Psychiatrists (RANZCP) to guide the clinical management of real-world depressive and bipolar disorders and to advise specifically on diagnosis and treatment strategies. The guideline focuses primarily on adults and briefly addresses special populations such as children and adolescents, pregnant and post-partum women, the elderly and those with common medical illnesses

2015 Royal Australian and New Zealand College of Psychiatrists

165. Effectiveness of Stroke Unit Care: A Special Report

Citations , Embase 1 exp Stroke/ or exp brain ischemia/ (273524) 2 exp intracranial hemorrhages/ use mesz (50434) 3 exp brain hemorrhage/ use emez (66291) 4 exp stroke patient/ use emez (5349) 5 (stroke or tia or transient ischemic attack or cerebrovascular apoplexy or cerebrovascular accident or cerebrovascular infarct* or brain infarct* or CVA or brain ajd2 isch?emia or (cerebral adj2 isch?emia) or (intracranial adj2 hemorrhag*) or (brain adj2 hemorrhag*)).ti,ab. (320222) 6 or/1-5 (509939) 7 exp (...) OR S5 42479 S5 (MH "Stroke Patients") 1812 S4 stroke or tia or transient ischemic attack or cerebrovascular apoplexy or cerebrovascular accident or cerebrovascular infarct* or brain infarct* or CVA or brain N2 isch?emia or cerebral N2 isch?emia or intracranial N2 hemorrhag* or brain N2 hemorrhag* 38045 S3 (MH "Intracranial Hemorrhage+") 4609 S2 (MH "Cerebral Ischemia+") 5334 S1 (MH "Stroke") 24768 Cochrane ID Search Hits #1 MeSH descriptor Stroke explode all trees 3785 #2 MeSH descriptor Brain

2014 Health Quality Ontario

166. Aortic Diseases

Diagnosis . . . . . . . . . . . . . . . . . . . . . . . . . . . .2905 7.2.4.1 Presentation . . . . . . . . . . . . . . . . . . . . . . . .2905 7.2.4.2 Diagnosticimaging . . . . . . . . . . . . . . . . . . . .2905 7.2.4.3 Screeningabdominalaorticaneurysminhigh-risk populations . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2905 7.2.5 Managementofsmallabdominalaorticaneurysms . .2906 7.2.5.1 Managementofriskfactors . . . . . . . . . . . . . .2906 7.2.5.2 Medicaltherapy (...) with the medical care of patients with this pathology.Selectedexpertsinthe?eldundertookacomprehensive reviewofthepublishedevidenceformanagement(includingdiagno- sis, treatment, prevention and rehabilitation) of a given condition accordingto ESC Committee forPractice Guidelines (CPG)policy. A critical evaluation of diagnostic and therapeutic procedures was performed including assessment of the risk-bene?t-ratio. Estimates of expected health outcomes for larger populations wereincluded, where data exist

2014 European Society of Cardiology

167. ESC/EACTS Guidelines in Myocardial Revascularisation

-- -- --- -- -- --- -- --- -- -- --- -- -- --- -- -- --- -- -- --- -- -- --- -- --- -- -- --- -- -- --- --- - - - - - - --- -- -- --- -- -- --- -- --- -- -- --- -- -- --- -- -- --- -- -- --- -- -- --- -- --- -- -- -- Keywords Acute coronarysyndromes † Bare-metal stents † Coronaryartery bypass grafting † Coronaryartery disease † Drug-eluting stents † EuroSCORE † Guidelines † Heart Team † Myocardial infarction † Myocardial ischaemia † Myocardial revascularization † Medical therapy † Percutaneous coronary intervention † Recommendation † Revascularization † Risk strati?cation † Stents † Stable angina † Stable coronary artery disease † ST-segment elevation myocardial infarction † SYNTAX score Table of Contents (...) Abbreviations and acronyms . . . . . . . . . . . . . . . . . . . . . . . .2544 1. Preamble . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2547 2. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2548 3. Scores and risk strati?cation . . . . . . . . . . . . . . . . . . . . . . .2549 4. Process for decision-making and patient information . . . . . . .2552 4.1 Patient information and informed consent . . . . . . . . . .2552 4.2 Multidisciplinary decision

2014 European Society of Cardiology

168. Smoking cessation

encouraged to take up referral to the local NHS stop smoking service: Pregnant women (including pregnant women who have stopped smoking in the past 2 weeks or who have a carbon monoxide reading of 7ppm or more) Mothers of young children, especially breastfeeding women. Young people aged 12-17. If a pregnant or breastfeeding women or young person is unwilling or unable to be referred: They should be offered practical advice to help them stop smoking. The risks and benefits of NRT should be discussed (...) smoking at age 60, 50, 40, or 30 adds about 3, 6, 9, or 10 years of life expectancy respectively [ ]. A prospective study of UK women (n= 1.2 million) showed that stopping smoking before the age of 40 avoids over 90% of the increased risk of dying caused by continuing to smoke [ ]. For people who stop smoking before the age of 50 years, the risk of dying of a smoking-related disease is reduced by 50% [ ]. Smoking-related diseases in other people exposed to environmental tobacco smoke, particularly

2018 NICE Clinical Knowledge Summaries

169. Antiplatelet treatment

of atherothrombotic events in people undergoing percutaneous coronary intervention (PCI). Aspirin is indicated for: Acute MI. Secondary prevention of MI, transient ischaemic attacks (TIA) and ischaemic cerebrovascular accidents (CVA). Stable angina pectoris, or history of unstable angina pectoris, except during the acute phase. Prevention of graft occlusion after coronary artery bypass grafting (CABG). Coronary angioplasty, except during the acute phase. Note: use of aspirin in primary prevention (...) for individuals in the primary prevention of CVD, where the evidence for benefit versus harm is very limited. Antiplatelet therapy is not recommended in people who do not have CVD, due to the increased risk of major bleeding [ ]. In a systematic review of six trials (n = 95,000), which compared the long-term use of aspirin vs control in people without overt CV or cerebrovascular disease, a risk reduction from 0.57% per year to 0.51% per year of serious vascular events was found, and major gastrointestinal (GI

2018 NICE Clinical Knowledge Summaries

170. Thirty-Day Readmissions After Hospitalization for Hypertensive Emergency. (PubMed)

with complications (10.2%), sepsis (5.9%), acute kidney injury (5.1%), and cerebrovascular accident (5.1%). Noncardiovascular causes accounted for 57.9% of readmissions. We found age <65 years (odds ratio, 1.21; 95% CI, 1.17-1.25; P<0.001), female sex (odds ratio, 1.09; 95% CI, 1.07-1.12; P<0.001), comorbid disease burden, substance use disorders, and socioeconomic risk factors to be significant predictors of readmission. One out of 6 patients hospitalized for hypertensive emergency had an unplanned 30-day (...) -cause unplanned 30-day readmission. Multivariable hierarchical logistic regression was used to identify independent predictors of readmission. There were 166 531 index hospitalizations for hypertensive emergency representative of 355 627 (SE, 9401) hospitalizations nationwide in 2013 to 2014. Mean age was 66.0 (SE, 0.14) years, and 53.7% were women. The overall incidence of unplanned 30-day readmissions was 17.8%. The most common causes of readmission were heart failure (14.2%), hypertension

2019 Hypertension

171. Semaglutide (Ozempic) - Diabetes Mellitus

9 2.1.2. Epidemiology and risk factors 10 2.1.3. Biologic features 10 2.1.4. Available therapies and unmet medical need 10 2.1.5. About the product 11 2.2. Quality aspects 11 2.2.1. Introduction 11 2.2.2. Active Substance 12 2.2.3. Finished Medicinal Product 15 2.2.4. Discussion on chemical, pharmaceutical and biological aspects 18 2.2.5. Conclusions on the chemical, pharmaceutical and biological aspects 19 2.2.6. Recommendation for future quality development 20 2.3. Non-clinical aspects 20 (...) 2.3.1. Introduction 20 2.3.2. Pharmacology 20 2.3.3. Pharmacokinetics 23 2.3.4. Toxicology 26 2.3.5. Ecotoxicity/environmental risk assessment 29 2.3.6. Discussion on non-clinical aspects 29 2.3.7. Conclusion on non-clinical aspects 30 2.4. Clinical aspects 30 2.4.1. Introduction 30 2.4.2. Pharmacokinetics 33 2.4.3. Pharmacodynamics 40 Cardiac repolarisation by QT interval evaluation 44 Exposure-response analyses 46 2.4.4. Discussion on clinical pharmacology 48 2.4.5. Conclusions on clinical

2018 European Medicines Agency - EPARs

172. Mortality before and after the 2003 invasion of Iraq: cluster sample survey. (PubMed)

the Falluja data, the risk of death is 1.5-fold (1.1-2.3) higher after the invasion. We estimate that 98000 more deaths than expected (8000-194000) happened after the invasion outside of Falluja and far more if the outlier Falluja cluster is included. The major causes of death before the invasion were myocardial infarction, cerebrovascular accidents, and other chronic disorders whereas after the invasion violence was the primary cause of death. Violent deaths were widespread, reported in 15 of 33 clusters (...) , and were mainly attributed to coalition forces. Most individuals reportedly killed by coalition forces were women and children. The risk of death from violence in the period after the invasion was 58 times higher (95% CI 8.1-419) than in the period before the war.Making conservative assumptions, we think that about 100000 excess deaths, or more have happened since the 2003 invasion of Iraq. Violence accounted for most of the excess deaths and air strikes from coalition forces accounted for most violent

2017 Lancet

173. ThermoCool SmartTouch catheter for percutaneous radiofrequency ablation in atrial fibrillation

). The risk of atrial fibrillation increases with age, and is more common in men than women. PVI catheter ablation is typically done under fluoroscopy guidance and therefore not recommended in people who are pregnant. Age, sex and pregnancy are protected characteristics under the Equality Act 2010. ThermoCool SmartT ouch catheter for percutaneous radiofrequency ablation in atrial fibrillation (MIB61) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms (...) ), including pericardial effusion, cardiac tamponade, atrioesophageal fistula, perforation, cerebrovascular accident and steam pop. ThermoCool SmartT ouch catheter for percutaneous radiofrequency ablation in atrial fibrillation (MIB61) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 12 of 47Malfunction (172 records), including catheter damage, internal components exposed, noise on all signals, char on catheter tip

2016 National Institute for Health and Clinical Excellence - Advice

174. Perjeta (pertuzumab (genetical recombination))

-dependent cell-mediated cytotoxicity (ADCC) against *************** cell line, whereas it exhibited ADCC activity against ****** cell line high-expressing HER2 (3+ by IHC) and against human breast cancer-derived ****** cell line. The applicant explained that pertuzumab induces ADCC activity against human breast cancer-derived cells in a manner dependent on HER2 expression level [see “2.B On ADCC activity”]. (f) Product-related substances In risk assessment and characterization to identify critical (...) on Day 1 of Cycle 1 was avoided in order to obtain the data for evaluating the presence or absence of pertuzumab-induced infusion reaction. Results showed that, in Cycle 1, the incidence of adverse events occurring during pertuzumab or placebo infusion was low in both groups and did not show any significant difference between the groups, suggesting that pertuzumab has only a low risk of causing infusion reaction. Also, in Cycle 2 and the subsequent cycles, administration of the 3 drugs on the same

2013 Pharmaceuticals and Medical Devices Agency, Japan

175. Stivarga (regorafenib hydrate)

under intermediate conditions. Since non-conformance to the specification in Related Substance A, a related substance, was observed in ** of 3 lots at 36 months in stability testing under intermediate conditions, PMDA asked the applicant to present their views on the risk associated with the establishment of a shelf life of 36 months at room temperature. The applicant responded as follows: Since the drug product is packaged in a humidity-protecting material that does not allow vapor to pass through

2013 Pharmaceuticals and Medical Devices Agency, Japan

176. Generalized anxiety disorder

health problem but are seeking reassurance about somatic symptoms. Be aware of (and inquire about) factors that increase the likelihood of a GAD diagnosis, including: Female sex. Family history of anxiety. Current physical or emotional stress. History of physical or emotional trauma. History of other anxiety disorders such as panic disorder, social phobia, or specific phobias. Chronic pain or physical illness (such as arthritis, cancer, coronary heart disease, cerebrovascular accident, or chronic (...) . For more information, see the section on Prescribing information. Do not offer an antipsychotic for the treatment of GAD in primary care. If a pregnant woman with GAD requires step 3 management : Ideally, a high-intensity psychological intervention should be offered first. If drug treatment is considered necessary in the first trimester (such as in a women for whom psychological intervention has proved ineffective), the potential risks and benefits should be discussed. For example, it is still unclear

2017 NICE Clinical Knowledge Summaries

177. Stroke and TIA

— atheroma and stenosis of the carotid arteries are commonly associated with stroke and TIA. Congestive heart failure. Congenital or structural heart disease including patent foramen ovale. Other factors such as: Age — the risk of having a stroke doubles every decade after the age of 55. Gender — Men are more likely than women to have a stroke at younger age. In women, an increased risk of stroke has been associated with current use of oral contraceptives, migraine with aura, the immediate postpartum (...) . In the UK, first ever stroke occurs in about 230/100,000 people per year and first-ever TIA in about 50/100,000 people per year. Once a person has had a stroke or TIA they are at high risk of a further vascular event. Stroke is the fourth single cause of mortality in the UK and can lead to many complications (such as neurological problems, depression and anxiety, communication difficulties, and difficulties with activities of daily living). Stroke and TIA generally present with sudden onset of focal

2017 NICE Clinical Knowledge Summaries

178. Management Practices and the Risk of Infection Following Cardiac Surgery

60 days of index cardiac surgical intervention; Superficial incisional surgical site infection (primary/secondary); Symptomatic urinary tract infection; Asymptomatic bacteriuria [ Time Frame: 60 Days ] Non-infection adverse events within 60 days of index cardiac surgical intervention; Neurologic Dysfunction; Transient ischemic attack; cerebrovascular accident (ischemic or hemorrhagic stroke); Myocardial infarction [ Time Frame: 60 Days ] Re-operation within 60 days of index cardiac surgical (...) Management Practices and the Risk of Infection Following Cardiac Surgery Management Practices and the Risk of Infection Following Cardiac Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Management

2010 Clinical Trials

179. Effect of gender on efficacy of preoperative intra-aortic balloon pump in high risk patients undergoing surgical coronary revascularisation. (PubMed)

if there is any benefit from preoperative IABP in high-risk patients undergoing CABG with the analysis of its determinants including gender.We randomly assigned 502 high-risk patients (351 men, 151 women) to the group receiving preoperative IABP support or to the control group with no preoperative IABP. Primary end-point was a major adverse cardiac or cerebrovascular event (MACCE), defined as death from any cause, myocardial infarction, cerebrovascular accident or repeat revascularisation within 30 days post (...) Effect of gender on efficacy of preoperative intra-aortic balloon pump in high risk patients undergoing surgical coronary revascularisation. There is no strong evidence supporting the use of preoperative intra-aortic balloon pump (IABP) in high-risk patients undergoing coronary artery bypass grafting (CABG). This issue has only been investigated in small studies which analysed the general population of patients, without focusing on specific subgroups, including gender.We sought to determine

2010 Kardiologia polska

180. Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors

Concurrent use of warfarin and strong inhibitors or CYP2D6 will not be allowed A personal history or a strong family of thromboembolism, including deep venous thrombosis (DVT), pulmonary embolus (PE), or cerebrovascular accident (CVA); a personal history of transient ischemic attack (TIA) or retinal vein thrombosis will also not be allowed; in addition, patients with a condition known to increase hypercoagulability, such as Factor V Leiden disease, will be excluded; patients with atrial fibrillation (...) Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2010 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>