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Cerebrovascular Accident Risk in Women

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141. Mechanical thrombectomy devices for acute ischaemic stroke

within 6 hours. Current NHS pathway People with suspected acute stroke should be admitted to the nearest accident and emergency department with a hyperacute stroke unit or a specialist stroke unit for immediate brain imaging (usually within 1 hour). If imaging confirms a diagnosis of acute ischaemic stroke then urgent thrombolysis should be given to try to restore blood flow in the brain. Other forms of pharmacological therapy are often used, whether or not thrombolysis has been attempted (...) and equality of opportunity between men and women, eliminate unlawful discrimination on grounds of race, disability, age, sex, gender reassignment, marriage and civil partnership, pregnancy and maternity (including women post-delivery), sexual orientation, and religion or belief (these are protected characteristics under the Equality Act 2010). Mechanical thrombectomy devices for acute ischaemic stroke (MIB153) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms

2018 National Institute for Health and Clinical Excellence - Advice

142. Contrast-induced Nephropathy

Effectiveness of Preventive Measures Structured Abstract Objective. To evaluate the comparative effectiveness of interventions (intravenous [IV] fluids, N-acetylcysteine, sodium bicarbonate, and statins, among others) to reduce the risk of contrast- induced nephropathy (CIN), need for renal replacement therapy, mortality, cardiac complications, prolonged length of stay, and other adverse events after receiving low-osmolar contrast media (LOCM) or iso-osmolar contrast media (IOCM). Data sources. We searched (...) . The team quantitatively pooled results of studies that were sufficiently similar using a random-effects model. We considered a 25-percent relative risk difference to be clinically important. Results. We found 163 randomized controlled trials (RCTs) and 23 prospective studies of interventions to prevent CIN, including 67 RCTs comparing N-acetylcysteine with IV saline versus IV saline with or without a placebo; 28 RCTs comparing IV sodium bicarbonate versus IV saline; 7 RCTs comparing IV sodium

2016 Effective Health Care Program (AHRQ)

143. Guidelines for adult stroke rehabilitation and recovery

in the 43 prevention studies reviewed was the Morse Fall Scale. 184 The Berg Balance Scale has demonstrated good sensitivity and specificity in predicting falls in individuals with stroke. 185 Several federal and professional associations have developed fall prevention toolkits that include risk assessment instru- ments and protocols (eg, the National Center of Patient Safety Falls Toolkit, the Centers for Disease Control and Prevention Stopping Elderly Accidents, Deaths and Injuries Toolkit, the AHRQ (...) ://stroke.ahajournals.org/ Downloaded from e2 Stroke June 2016 Conclusions—As systems of care evolve in response to healthcare reform efforts, postacute care and rehabilitation are often considered a costly area of care to be trimmed but without recognition of their clinical impact and ability to reduce the risk of downstream medical morbidity resulting from immobility, depression, loss of autonomy, and reduced functional independence. The provision of comprehensive rehabilitation programs with adequate resources, dose

2016 American Academy of Neurology

144. AHA/ASA Guidelines for Adult Stroke Rehabilitation and Recovery

recognition of their clinical impact and ability to reduce the risk of downstream medical morbidity resulting from immobility, depression, loss of autonomy, and reduced functional independence. The provision of comprehensive rehabilitation programs with adequate resources, dose, and duration is an essential aspect of stroke care and should be a priority in these redesign efforts. ( Stroke. 2016;47:e98-e169. DOI: 10.1161/STR.0000000000000098.) Introduction Between 2000 and 2010, the relative rate of stroke (...) et al and updated by Langhorne and Holmqvist found that ESD services reduce inpatient length of stay and adverse events (eg, readmission rates) while increasing the likelihood of independence and living at home. Several recent systematic reviews have also reported that ESD after stroke was associated with shorter hospital lengths of stay, lower overall costs of care, lower risk of institutionalization, and no adverse effects on functional recovery. To be effective, ESD should be considered

2016 American Heart Association

145. American Association of Clinical Endocrinologists and American College of Endocrinology Clinical Practice Guidelines for Comprehensive Medical Care of Patients with Obesity

and obesity? Q2.2. What are the best anthropomorphic criteria for defining excess adiposity in the diagnosis of overweight and obesity in the clinical setting? 34 Q2.3. Does waist circumference provide information in addition to body mass index (BMI) to indicate adiposity risk? 34 Q2.4. Do BMI and waist circumference accurately capture adiposity risk at all levels of BMI, ethnicity, gender, and age? 34 Q3. What are the weight-related complications that are either caused or exacerbated by excess adiposity (...) ? 37 Q3.1. Diabetes risk, metabolic syndrome, and prediabetes (IFG, IGT) 37 Q3.2. Type 2 diabetes 39 Q3.3. Dyslipidemia 40 Q3.4. Hypertension 41 Q3.5. Cardiovascular disease and cardiovascular disease mortality 42 Q3.6. Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 44 Q3.7. Polycystic ovary syndrome (PCOS) 46 Q3.8. Female infertility 47 Q3.9. Male hypogonadism 48 Q3.10. Obstructive sleep apnea 50 Q3.11. Asthma/reactive airway disease 50 Q3.12. Osteoarthritis 51 Q3.13. Urinary stress

2016 American Association of Clinical Endocrinologists

146. Acne clinical guideline

. Approximately 50 million people in the United States have AV. x 5 White, G.M. Recent findings in the epidemiologic evidence, classification, and subtypes of acne vulgaris. J Am Acad Dermatol . 1998 ; 39 : S34–S37 | | | | Acne affects approximately 85% of teenagers, but can occur in most age groups x 6 Bhate, K. and Williams, H.C. Epidemiology of acne vulgaris. Br J Dermatol . 2013 ; 168 : 474–485 | | | and can persist into adulthood. The prevalence of acne in adult women is about 12%. x 7 Goulden, V (...) , C.W., Lee, D.H., Kim, H.S. et al. The clinical features of late onset acne compared with early onset acne in women. J Eur Acad Dermatol Venereol . 2011 ; 25 : 454–461 | | , x 33 Dobrev, H. Fluorescence diagnostic imaging in patients with acne. Photodermatol Photoimmunol Photomed . 2010 ; 26 : 285–289 | | , x 34 Choi, C.W., Choi, J.W., and Youn, S.W. Subjective facial skin type, based on the sebum related symptoms, can reflect the objective casual sebum level in acne patients. Skin Res Technol

2016 American Academy of Dermatology

147. Bevacizumab, Docetaxel, and Carboplatin in Treating Women With Stage II or Stage III Breast Cancer

failure No history of cancer except for carcinoma in situ of the uterine cervix or nonmelanoma skin cancer No history or evidence of inherited bleeding diathesis or coagulopathy with the risk of bleeding No uncontrolled hypertension (systolic BP > 150 mm Hg and/or diastolic BP > 100 mm Hg) No history or evidence of clinically significant cardiovascular disease, including any of the following: Cerebrovascular accident (CVA) or stroke within the past 6 months Myocardial infarction (MI) within the past 6 (...) Bevacizumab, Docetaxel, and Carboplatin in Treating Women With Stage II or Stage III Breast Cancer Bevacizumab, Docetaxel, and Carboplatin in Treating Women With Stage II or Stage III Breast Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2010 Clinical Trials

148. Bevacizumab and Paclitaxel or Bevacizumab, Cyclophosphamide, and Capecitabine as First-Line Therapy in Treating Women With Locally Advanced, Recurrent, or Metastatic Breast Cancer

hypertension ≥ 140/100 mm Hg Myocardial infarction within the past 12 months Cerebrovascular accident or stroke within the past 6 months History of hemorrhagic disorders No psychiatric disorder precluding understanding of information on trial-related topics, giving informed consent, filling out quality-of-life forms, or interfering with compliance for oral drug intake PRIOR CONCURRENT THERAPY: No prior chemotherapy for metastatic or locally recurrent breast cancer No prior radiotherapy for metastatic (...) Bevacizumab and Paclitaxel or Bevacizumab, Cyclophosphamide, and Capecitabine as First-Line Therapy in Treating Women With Locally Advanced, Recurrent, or Metastatic Breast Cancer Metronomic Therapy in Metastatic Breast Cancer. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2010 Clinical Trials

149. Carfilzomib (multiple myeloma) - Addendum to Commission A17-38

disorders 39 (9.9) 24 (6.2) Pulmonary embolism 12 (3.1) 8 (2.1) General disorders and administration site conditions 35 (8.9) 28 (7.2) Pyrexia 14 (3.6) 11 (2.8) Progression of a disease 4 (1.0) 8 (2.1) Gastrointestinal disorders 25 (6.4) 20 (5.1) Diarrhoea 7 (1.8) 9 (2.3) Blood and lymphatic system disorders 21 (5.4) 23 (5.9) Anaemia 8 (2.0) 10 (2.6) Febrile neutropenia 8 (2.0) 4 (1.0) Nervous system disorders 21 (5.4) 27 (6.9) Cerebrovascular accident 4 (1.0) 10 (2.6) Vascular disorders 18 (4.6) 15 (...) , benefit assessment, NCT01080391, NCT01568866 Addendum A18-04 Version 1.1 Carfilzomib – Addendum to Commission A18-04 1 February 2018 Institute for Quality and Efficiency in Health Care (IQWiG) - iii - Table of contents Page List of tables iv List of figures vi List of abbreviations vii 1 Background 1 2 Assessment 3 2.1 Assessment of the data on the ASPIRE study subsequently submitted 3 2.1.1 Risk of bias 3 2.1.2 Results 5 2.1.3 Probability and extent of added benefit 10 2.1.3.1 Assessment of the added

2018 Institute for Quality and Efficiency in Healthcare (IQWiG)

150. Childhood Hematopoietic Cell Transplantation (PDQ®): Health Professional Version

comparison.[ , ] However, for very high-risk patients such as those with early relapse of acute lymphoblastic leukemia (ALL), randomized trials have not been feasible because of investigator bias.[ , ] In general, HCT typically offers benefit only to children at high risk of relapse with standard chemotherapy approaches. Accordingly, treatment schemas that accurately identify these high-risk patients and offer HCT if reasonably HLA-matched donors are available have come to be the preferred approach (...) for many diseases.[ ] Less well-established, higher-risk approaches to HCT are generally reserved for only the very highest-risk patients. However, higher-risk approaches such as haploidentical transplantation are becoming safer and more efficacious and are increasingly being used interchangeably with fully matched allogeneic approaches.[ - ] (Refer to the section of this summary for more information.) When comparisons of similar patients treated with HCT or chemotherapy are made in the setting where

2018 PDQ - NCI's Comprehensive Cancer Database

151. Physical Activity Counselling

or cerebrovascular) adj (accident* or infarct*)) or CVA or cerebrovascular apoplexy or brain infarct* or (brain adj2 isch?emia) or (cerebral adj2 isch?emia) or (intracranial adj2 h?emorrhag*) or (brain adj2 h?emorrhag*)).ti,ab. 190539 8 exp Heart Failure/ 88591 9 (((cardia? or heart) adj (decompensation or failure or incompetence or insufficiency)) or cardiac stand still or ((coronary or myocardial) adj (failure or insufficiency))).ti,ab. 128470 10 exp Pulmonary Disease, Chronic Obstructive/ 36229 11 exp (...) +") or (MH "After Care") or (MH "Recovery") or (MH "Continuity of Patient Care+") 44,877 S2 ((patient* N2 discharge*) or aftercare or after care or post medical discharge* or postdischarge* or post discharge* or convalescen*) 29,136 S3 (MH "Stroke+") or (MH "Cerebral Ischemia+") or (MH "Intracranial Hemorrhage+") or (MH "Stroke Patients") 48,958 S4 (stroke or poststroke or tia or transient ischemic attack or ((cerebral vascular or cerebrovascular) N1 (accident* or infarct*)) or CVA or cerebrovascular

2015 Health Quality Ontario

152. Effects of Increased Intensity of Physiotherapy on Patient Outcomes After Stroke

or cerebrovascular accident or cerebrovascular infarct* or brain infarct* or CVA or (brain adj2 isch?emia) or (cerebral adj2 isch?emia) or (intracranial adj2 hemorrhag*) or (brain adj2 hemorrhag*)).ti,ab. 402906 6 or/1-5 593865 7 exp Rehabilitation/ or exp Rehabilitation Nursing/ 358247 8 exp Rehabilitation Centers/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed 12317 9 exp rehabilitation center/ use emez 8433 10 exp rehabilitation medicine/ use emez or exp rehabilitation research/ use emez 4826 11 exp (...) *) 237,534 S10 (MH "Physical Medicine") 1,144 S9 (MH "Stroke+/RH") 7,150 S8 (MH "Rehabilitation Nursing") 2,129 S7 (MH "Rehabilitation+") OR (MH "Rehabilitation Centers+") 167,454 S6 S1 OR S2 OR S3 OR S4 OR S5 61,146 S5 (MH "Stroke Patients") 2,333 S4 (stroke or tia or transient ischemic attack or cerebrovascular apoplexy or cerebrovascular accident or cerebrovascular infarct* or brain infarct* or CVA or (brain N2 isch?emia) or (cerebral N2 isch?emia) or (intracranial N2 hemorrhag*) or (brain N2

2015 Health Quality Ontario

153. Pressure Ulcer Multidisciplinary Teams via Telemedicine (PUMTT): A Pragmatic Randomized Controlled Trial in Long-Term Care

hazards model. Treatment was coded as a time-dependent covariate. Additional potential confounding covariates added to the model were wound area at the first visit (log- transformed), paraplegia or hemiplegia, diabetes, mental status, sex, congestive heart failure, continence, cerebrovascular accident (stroke), body mass index (BMI), and Charlson Comorbidity Index. The models were stratified by wound stage and wound location (grouped into buttock/coccyx/sacrum/hip/ischium, foot/heel/ankle bone (...) for Wound Care Merrick Zwarenstein, MBBCh, MSc(CHDC), MSc(Comm Hlth), PhD, Sunnybrook Research Institute Laura Teague, RN-EC, NP, MN, St. Michael’s Hospital George Tomlinson, PhD, University of Toronto Kevin Woo, PhD, RN, ACNP, GNC(C), FAPWCA, Women’s College Research Institute Matthew Kowgier, MSc, PhD(c), University of Toronto Ann-Marie McLaren, DCh, BSc, MClSc, St. Michael’s Hospital Janice Hon, OT Reg(Ont), St. Michael’s Hospital Linda Norton, OT Reg(Ont), Shoppers Home Health Care Josephine Santos

2015 Health Quality Ontario

154. Retinal Vein Occlusion (RVO)

the association with hypertension and diabetes some studies have found a higher incidence of cardiovascular and cerebrovascular morbidity and mortality in RVO patients compared to controls. However this has not been found in all studies. The systemic conditions for which a patient with RVO may be at greater risk are: ? Stroke: conflicting reports on associations have been noted (see below)41, 42, 43, 44 Cardiovascular disease under age 70 was noted in one study43 but not in another report5 ? Peripheral (...) and associates reported that RVO did not increase the rate of stroke development in a hospital-based study on 549 RVO patients after a mean follow-up period of 9.08 years.42 These findings were confirmed in a retrospective population based study in Taiwan on 350 RVO versus 2100 controls.43 However, Cugati et al found that men with RVO are associated with a non-significant 2.3-fold higher risk of cerebrovascular mortality for all ages in a pooled cohort of two-population based studies.44 Similarly

2015 Royal College of Ophthalmologists

155. Colonoscopy Outcomes by Duration of NPO Status Prior to Colonoscopy with Moderate or Deep Sedation

SUMMARY Introduction 1 Methods 2 Data Sources and Searches 2 Study Selection 2 Data Abstraction and Risk of Bias Assessment 2 Data Synthesis and Analysis 2 Results 3 Results of Literature Search 3 Overview 3 Executive Summary Table 1. Summary of Outcomes Reported in Included Studies 3 Summary of Results for Key Questions 4 Discussion 6 Key Findings and Strength of Evidence 6 Applicability 7 Research Gaps/Future Research 7 Conclusions 7 Abbreviations Table 8 INTRODUCTION 9 METHODS Topic Development 11 (...) Search Strategy 11 Study Selection 11 Data Abstraction 11 Risk of Bias Assessment 12 Data Synthesis 12 Rating the Body of Evidence 12 Peer Review 12 ii NPO Status Prior to Colonoscopy Evidence-based Synthesis Program RESULTS Literature Flow 13 Overview 14 Key Question 1. Does the incidence of aspiration and other anesthesia-related harms for colonoscopy vary by NPO status or bowel prep timing (eg, > 6 hours, 2-6 hours, 6 hours, 2-6 hours, 6 hours, 2-6 hours, 6 hours, 2-6 hours, 8 hours indicates

2015 Veterans Affairs Evidence-based Synthesis Program Reports

156. Breast Cancer Treatment (PDQ®): Health Professional Version

. In the last decade, women have refrained from using postmenopausal hormones, and breast cancer incidence has declined, but not to the levels seen before the widespread use of screening mammography.[ ] Anatomy Anatomy of the female breast. The nipple and areola are shown on the outside of the breast. The lymph nodes, lobes, lobules, ducts, and other parts of the inside of the breast are also shown. Risk Factors Increasing age is the most important risk factor for most cancers. Other risk factors for breast (...) ).[ ] Personal history of breast cancer.[ ] Personal history of benign breast disease (BBD) (proliferative forms of BBD).[ - ] Radiation exposure to breast/chest. [ ] Age-specific risk estimates are available to help counsel and design screening strategies for women with a family history of breast cancer.[ , ] Of all women with breast cancer, 5% to 10% may have a germline mutation of the genes BRCA1 and BRCA2 .[ ] Specific mutations of BRCA1 and BRCA2 are more common in women of Jewish ancestry

2018 PDQ - NCI's Comprehensive Cancer Database

157. Acute pain management: scientific evidence (3rd Edition)

: Scientific Evidence xv CONTENTS 9. SPECIFIC CLINICAL SITUATIONS 237 9.1 Postoperative pain 237 9.1.1 Risks of acute postoperative neuropathic pain 237 9.1.2 Acute postamputation pain syndromes 238 9.1.3 Other postoperative pain syndromes 240 9.1.4 Day-stay or short-stay surgery 242 9.1.5 Cranial neurosurgery 245 9.2 Acute pain following spinal cord injury 247 9.3 Acute burn injury pain 249 9.3.1 Management of procedural pain 250 9.3.2 Non-pharmacological pain management 251 9.4 Acute back pain 252 9.5 (...) pain after surgery 11 1.3 Risk factors for chronic postsurgical pain 11 1.4 Definitions of pre-emptive and preventive analgesia 13 1.5 Summary of studies according to target agent administered 14 1.6 Metabolic and endocrine responses to injury 17 2.1 Fundamentals of a pain history 36 3.1 Possible benefits of an Acute Pain Service 51 4.1 Antidepressants for the treatment of neuropathic pain 89 6.1 The 2007 Oxford league table of analgesic efficacy 154 9.1 Taxonomy of acute pain associated

2015 National Health and Medical Research Council

158. Guidance on the clinical management of depressive and bipolar disorders, specifically focusing on diagnosis and treatment strategies

disorders, and the potential risk of further over pathologising healthy children. It is best seen as a category that enables further research on the natural history and best management of such presentations. g Premenstrual Dysphoric Disorder (PMDD) is also a new diagnosis used to describe women of menstruating age who experience severe dysphoria, irritability or mood swings in the week prior to the onset of menses and finishing a few days after the onset of menses. These symptoms need (...) Disorders Clinical Practice Guideline (Mood Disorders CPG) has been developed by the Royal Australian and New Zealand College of Psychiatrists (RANZCP) to guide the clinical management of real-world depressive and bipolar disorders and to advise specifically on diagnosis and treatment strategies. The guideline focuses primarily on adults and briefly addresses special populations such as children and adolescents, pregnant and post-partum women, the elderly and those with common medical illnesses

2015 Royal Australian and New Zealand College of Psychiatrists

159. Effectiveness of Stroke Unit Care: A Special Report

Citations , Embase 1 exp Stroke/ or exp brain ischemia/ (273524) 2 exp intracranial hemorrhages/ use mesz (50434) 3 exp brain hemorrhage/ use emez (66291) 4 exp stroke patient/ use emez (5349) 5 (stroke or tia or transient ischemic attack or cerebrovascular apoplexy or cerebrovascular accident or cerebrovascular infarct* or brain infarct* or CVA or brain ajd2 isch?emia or (cerebral adj2 isch?emia) or (intracranial adj2 hemorrhag*) or (brain adj2 hemorrhag*)).ti,ab. (320222) 6 or/1-5 (509939) 7 exp (...) OR S5 42479 S5 (MH "Stroke Patients") 1812 S4 stroke or tia or transient ischemic attack or cerebrovascular apoplexy or cerebrovascular accident or cerebrovascular infarct* or brain infarct* or CVA or brain N2 isch?emia or cerebral N2 isch?emia or intracranial N2 hemorrhag* or brain N2 hemorrhag* 38045 S3 (MH "Intracranial Hemorrhage+") 4609 S2 (MH "Cerebral Ischemia+") 5334 S1 (MH "Stroke") 24768 Cochrane ID Search Hits #1 MeSH descriptor Stroke explode all trees 3785 #2 MeSH descriptor Brain

2014 Health Quality Ontario

160. Aortic Diseases

Diagnosis . . . . . . . . . . . . . . . . . . . . . . . . . . . .2905 7.2.4.1 Presentation . . . . . . . . . . . . . . . . . . . . . . . .2905 7.2.4.2 Diagnosticimaging . . . . . . . . . . . . . . . . . . . .2905 7.2.4.3 Screeningabdominalaorticaneurysminhigh-risk populations . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2905 7.2.5 Managementofsmallabdominalaorticaneurysms . .2906 7.2.5.1 Managementofriskfactors . . . . . . . . . . . . . .2906 7.2.5.2 Medicaltherapy (...) with the medical care of patients with this pathology.Selectedexpertsinthe?eldundertookacomprehensive reviewofthepublishedevidenceformanagement(includingdiagno- sis, treatment, prevention and rehabilitation) of a given condition accordingto ESC Committee forPractice Guidelines (CPG)policy. A critical evaluation of diagnostic and therapeutic procedures was performed including assessment of the risk-bene?t-ratio. Estimates of expected health outcomes for larger populations wereincluded, where data exist

2014 European Society of Cardiology

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