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Cerebrovascular Accident Risk in Women

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61. Phase 2 Study in Japanese Patients With Intermediate-2 or High Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis With Splenomegaly

. Uncontrolled congestive heart failure (New York Heart Association Classification 3 or 4), angina, myocardial infarction, cerebrovascular accident, coronary/peripheral artery bypass graft surgery, transient ischemic attack, or pulmonary embolism within 3 months prior to initiation of study drug. Participation in any study of an investigational agent (drug, biologic, device) within 30 days, unless during nontreatment phase. Prior treatment with a JAK 2 Inhibitor. Treatment with aspirin in doses >150 mg/day (...) Phase 2 Study in Japanese Patients With Intermediate-2 or High Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis With Splenomegaly Phase 2 Study in Japanese Patients With Intermediate-2 or High Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis With Splenomegaly - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting

2012 Clinical Trials

62. Study of Preoperative Therapy With Pazopanib (Votrient®) to Treat High-risk Soft Tissue Sarcoma

failure, as defined by the New York Heart Association (NYHA) Poorly controlled hypertension [defined as systolic blood pressure (SBP) of ≥140 mmHg or diastolic blood pressure (DBP) of ≥ 90mmHg]. Cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past 6 months. Major surgery or trauma within 28 days prior to first dose of investigational product and/or presence of any non-healing wound, fracture, or ulcer (...) Study of Preoperative Therapy With Pazopanib (Votrient®) to Treat High-risk Soft Tissue Sarcoma Study of Preoperative Therapy With Pazopanib (Votrient®) to Treat High-risk Soft Tissue Sarcoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2012 Clinical Trials

63. Hybrid repair of thoracic aortic lesions for zone 0 and 1 in high risk patients. (Full text)

patients required hemodialysis postoperatively (7.9%), 18 patients (47.4%) required prolonged mechanical ventilation for respiratory insufficiency. Paraplegia occurred in one patient (2.7%), and five patients suffered a cerebrovascular accident (13.1%). There were four early type I and two type II endoleaks. Overall 30-day mortality was 23.7%.The hybrid approach for repair of the aortic arch pathologies is feasible in patients unfit for open repair. We present the results of performing different (...) Hybrid repair of thoracic aortic lesions for zone 0 and 1 in high risk patients. Some patients with aortic arch or descending thoracic aorta pathologies are not suited for open repair because of comorbidities that may increase their risk of procedural complications or death. Endovascular approaches may also be difficult when there are inadequate proximal landing zones in the aortic arch. We report our experience using rerouting techniques with bypass, stenting of the branches, or a combination

2011 Journal of Vascular Surgery PubMed

64. Patients With High-risk Acute Coronary Syndrome Without ST-segment Elevation

for the study: 12-derivation-ECG with persistent ST-segment elevation; Diagnosis of angina by secondary cause (e.g., anemia, fever, hypovolemia, dehydration, use of cocaine); Use of non-fractionated heparin or low-molecular weight heparin in the prior 48 to the randomization; Concomitant diseases, such as severe renal failure (creatinine clearance lower than 30ml/min.) and hepatic, or other significant comorbidities under investigator judgment; Recent hemorrhagic cerebrovascular accident (last 12 months (...) to the randomization; Concomitant diseases, such as severe renal failure (creatinine clearance lower than 30ml/min.) and hepatic, or other significant comorbidities under investigator judgment; Recent hemorrhagic cerebrovascular accident (last 12 months); Patient scheduled for cardiac surgery of myocardial revascularization; Use of drugs, alcohol abuse; Pregnancy or lactation; Recent neurosurgery or ophthalmic surgery (last 3 months); History or diagnosis of coagulopathy; Medical record containing allergy

2011 Clinical Trials

65. IoN- Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer Patients

to interfere with the patient's ability to be able to comply with treatment and/or follow-up for at least 5 years The following GI conditions: dysphagia, oesophageal stricture, active gastritis, gastric erosions, peptic ulcer, suspected reduced gastrointestinal motility MDT decision against ablation or suitability for trial in light of severe co-morbid condition/s including: Unstable angina Recent myocardial infarction or cerebrovascular accident (CVA) Severe labile hypertension Any patient who cannot (...) reduced gastrointestinal motility MDT decision against ablation or suitability for trial in light of severe co-morbid condition/s including: Unstable angina Recent myocardial infarction or cerebrovascular accident (CVA) Severe labile hypertension Any patient who cannot comply with radiation protection including: patients with learning difficulties patients with dementia patients with a tracheostomy that require nursing care patients requiring frequent nursing/ medical supervisi Contacts and Locations

2011 Clinical Trials

66. The Effect of Blueberry Powder Supplementation on Cardiovascular Risk Factors in Subjects With the Metabolic Syndrome

cardiovascular dysfunction and/or history (within the preceding 6 months) of significant cardiovascular dysfunction, e.g., congestive heart failure or serious arrhythmia, myocardial infarction, cardiac surgery; transient ischemic attacks or cerebrovascular accident during the preceding six months; diagnosis of symptomatic autonomic neuropathy with a history of orthostatic hypertension, syncope, or hypertension with a systolic blood pressure of ≥180 mm Hg or diastolic blood pressure ≥110 mm Hg at the time (...) The Effect of Blueberry Powder Supplementation on Cardiovascular Risk Factors in Subjects With the Metabolic Syndrome The Effect of Blueberry Powder Supplementation on Cardiovascular Risk Factors in Subjects With the Metabolic Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2011 Clinical Trials

67. First Line Pazopanib in Poor Risk Patients With Metastatic Renal Cell Carcinoma

Symptomatic peripheral vascular disease Class III or IV congestive heart failure, as defined by the New York Heart Association (NYHA) Poorly controlled hypertension History of cerebrovascular accident including transient ischemic attack (TIA), pulmonary embolism or untreated deep venous thrombosis (DVT) within the past 6 months. Note: Subjects with recent DVT who have been treated with therapeutic anti-coagulating agents for at least 6 weeks are eligible Prior major surgery or trauma within 28 days prior (...) First Line Pazopanib in Poor Risk Patients With Metastatic Renal Cell Carcinoma First Line Pazopanib in Poor Risk Patients With Metastatic Renal Cell Carcinoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2011 Clinical Trials

68. Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer

of stroke). History of inflammatory bowel disease and/or acute/subacute bowel occlusion Serious, non-healing wound, ulcer, or bone fracture Evidence of bleeding diathesis or coagulopathy. Uncontrolled hypertension Clinically significant (i.e. active) cardiovascular disease, for example cerebrovascular accidents (≤ 6 months), myocardial infarction (≤ 6 months), unstable angina, New York Heart Association (NYHA) grade II or greater congestive heart failure, serious cardiac arrhythmia requiring medication (...) Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2011 Clinical Trials

69. Transient Ischemic Attack (TIA) Triage and Evaluation of Stroke Risk

the diagnosis of TIA and to define the risk of stroke after a TIA. Condition or disease Cerebrovascular Accident Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 262 participants Observational Model: Cohort Time Perspective: Prospective Official Title: TIA Triage Trial and Evaluation of Vascular-Specific Inflammatory BiomarkerLp-PLA2 as a Stratification Tool for TIA Triage and Stroke Risk Study Start Date : September 2010 Estimated Primary Completion Date (...) Transient Ischemic Attack (TIA) Triage and Evaluation of Stroke Risk Transient Ischemic Attack (TIA) Triage and Evaluation of Stroke Risk - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Transient Ischemic

2011 Clinical Trials

70. Guidelines on Diabetes, Pre-Diabetes and Cardiovascular Diseases developed in collaboration with the EASD (Full text)

is not recommended for CV risk stratification. 5.1 Diabetes, pre-diabetes, and cardiovascular risk The Emerging Risk Factor Collaboration, a meta-analysis of 102 prospective studies, showed that DM in general (data on DM type were unavailable) confers a two-fold excess risk of vascular outcomes (coronary heart disease, ischaemic stroke, and vascular deaths), independent of other risk factors ( Figure ). The excess relative risk of vascular events with DM was greater in women and at younger ages. Both relative (...) diseases of the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD), European Heart Journal , , ehz486, Download citation file: © 2019 Oxford University Press Navbar Search Filter Mobile Microsite Search Term Close search filter search input , , , , , , , , , , , Table of contents Abbreviations and acronyms 4 1 Preamble 6 2 Introduction 8 3 What is new in the 2019 Guidelines? 9 4 Diagnosis of diabetes and pre-diabetes 11 5 Cardiovascular risk assessment

2019 European Society of Cardiology PubMed

71. Diagnosis and management of epilepsy in adults

epilepticus 23 4.11 Patients with recurrent prolonged or serial seizures in the community 26 4.12 Drugs which exacerbate epileptic seizures 27 4.13 Management of patients with epilepsy in the perioperative period 27 4.14 Management of older people with epilepsy 27 4.15 Management of people with learning disability and epilepsy 29 5 Epilepsy and women’s health 31 5.1 Contraception 31 5.2 Preconceptual counselling 35 5.3 Risks of inheriting epilepsy 36 5.4 Pregnancy 38 5.5 Labour and birth 40 (...) and around 50% of referrals to first seizure clinics result from events which are not epileptic. There is evidence that management can sometimes be suboptimal, 3-5 and with some intervention, readily improved. 3, 5 Epilepsy carries a small but significant risk of mortality which is increased where seizure control is incomplete. Specific concerns surround initial diagnosis, drug treatment, management of pregnant women with epilepsy and the provision of patient information. It is likely that the incidence

2018 SIGN

72. Excess mortality and life expectancy of individuals with type 1 diabetes: a rapid review

Nervous System CVA Cerebrovascular Accident CV Cardiovascular CVD Cardiovascular disease DKA Diabetic Keto-Acidosis eLE estimated LE ESM Electronic Supplementary Material ESRD End Stage Renal Disease eYLL estimated YLL FU Follow-Up (e)GFR (estimated) Glomerular Filtration Rate HbA1c glycated Haemoglobin A1 HR Hazard ratio IHD Ischaemic Heart Disease LDL-c LDL cholesterol LE Life Expectancy M-A Meta-Analysis MA Micro-Albuminuria OBS Opvolgingsbureau voor tarificatie – Bureau de suivi de la tarification (...) . 3.2.3. The Swedish registry-based cohort study by Petrie et al. From June 2002 till November 2007 the LE at age 20 of Swedes with T1D increased by approximately 2 years for men but minimally for women (not significant). 12 These changes have been driven by a decrease in cardiovascular mortality. The strengths of this study are the large representative sample, the relatively long length of follow-up and the measurement of clinical risk factors. Data on age at diagnosis, HbA1c, presence/absence

2019 Belgian Health Care Knowledge Centre

73. Guidelines on Diagnosis and Management of Syncope (Full text)

evaluation and management according to risk stratification 1892 4.1 Initial evaluation 1892 4.1.1 Diagnosis of syncope 1893 4.1.2 Management of syncope in the emergency department based on risk stratification 1895 4.2 Diagnostic tests 1900 4.2.1 Carotid sinus massage 1900 4.2.2 Orthostatic challenge 1901 4.2.2.1 Active standing 1901 4.2.2.2 Tilt testing 1903 4.2.3 Basic autonomic function tests 1904 4.2.3.1 Valsalva manoeuvre 1904 4.2.3.2 Deep breathing 1904 4.2.3.3 Other autonomic function tests 1904 (...) supraventricular tachycardia 1923 5.4.2.2 Paroxysmal ventricular tachycardia 1923 5.5 Treatment of syncope secondary to structural cardiac, cardiopulmonary, and great vessel disease 1925 5.6 Treatment of unexplained syncope in patients at high risk of sudden cardiac death 1925 5.6.1 Definition 1925 5.6.2 Left ventricular systolic dysfunction 1925 5.6.3 Hypertrophic cardiomyopathy 1926 5.6.4 Arrhythmogenic right ventricular cardiomyopathy 1926 5.6.5 Patients with inheritable arrhythmogenic disorders 1926

2018 European Society of Cardiology PubMed

74. Multimorbidity: a priority for global health research

that it is often more prevalent in those of lower socioeconomic status, and may be influenced by other variables such as sex, ethnicity, and several health-related behaviours already known to increase the risk of single chronic conditions. Multimorbidity also appears to be increasingly common in low- and middle- income countries (LMICs), where the burden of chronic physical conditions (or non-communicable diseases (NCDs)) such as diabetes and heart conditions is rising and augmenting existing burdens (...) conditions, such as coronary heart disease and cerebrovascular disease, which share a common aetiology (e.g. high blood pressure), frequently co-exist. In other cases – termed discordant multimorbidity – the co-existing conditions appear to be unrelated to each other or require different management approaches. In this regard, it is notable that there are data indicating that chronic physical and mental health conditions commonly co-exist. Some common clusters of conditions appear to vary by region

2018 Academy of Medical Sciences

75. Heart Disease and Stroke Statistics (Full text)

. Physical Inactivity e99 5. Nutrition e119 6. Overweight and Obesity e138 Health Factors and Other Risk Factors 7. High Blood Cholesterol and Other Lipids e161 8. High Blood Pressure e174 9. Diabetes Mellitus e193 10. Metabolic Syndrome e212 11. Kidney Disease e233 12. Sleep e249 Cardiovascular Conditions/Diseases 13. Total Cardiovascular Diseases e257 14. Stroke (Cerebrovascular Disease) e281 15. Congenital Cardiovascular Defects and Kawasaki Disease e327 16. Disorders of Heart Rhythm e346 17. Sudden (...) e511 26. Economic Cost of Cardiovascular Disease e516 Supplemental Materials 27. At-a-Glance Summary Tables e522 28. Glossary e526 Summary Each year, the American Heart Association (AHA), in conjunction with the National Institutes of Health and other government agencies, brings together in a single document the most up-to-date statistics related to heart disease, stroke, and the cardiovascular risk factors in the AHA’s My Life Check − Life’s Simple 7 ( ), which include core health behaviors

2019 American Heart Association PubMed

76. AIM Clinical Appropriateness Guidelines for Sleep Disorder Management

sleep study which did not diagnose OSA in a patient with ongoing clinical suspicion of OSA. 10. Patient is oxygen dependent for any reason 11. History of cerebrovascular accident (CVA) within the preceding 30 days 12. Chronic opiate narcotic use, when discontinuation is not an option. Diagnostic sleep testing for patients using opiate narcotics for acute self-limited conditions should ideally be deferred until the medications have been stopped. 13. Body Mass Index (BMI) >33 and elevated serum (...) (persistent hypertension in a patient taking three or more antihypertensive medications). Because of daytime sleepiness, deaths related to motor vehicle accidents are also more common in patients with OSA. Diagnosis of OSA: Although OSA may be suspected based on the symptoms described above, physical exam findings (e.g., obesity, increased neck circumference, retrognathia etc.), or presence of comorbidities, the diagnosis must be confirmed by a sleep test. During sleep testing, various physiological

2019 AIM Specialty Health

77. AIM Clinical Appropriateness Guidelines for Advanced Imaging of the Heart.

, or exercise-induced dizziness, lightheadedness, or near syncope, etc. ? With high risk of CAD (SCORE) ? Patients with any cardiac symptom who have diseases/conditions with which coronary artery disease commonly coexists such as: ? Diabetes mellitus; OR ? Abdominal aortic aneurysm; OR ? Established and symptomatic peripheral vascular disease; OR ? Prior history of cerebrovascular accident (CVA), transient ischemic attack (TIA) or carotid endarterectomy (CEA) or high grade carotid stenosis (>70 (...) ; OR ? Prior history of cerebrovascular accident (CVA), transient ischemic attack (TIA) or carotid endarterectomy (CEA) or high grade carotid stenosis (>70%); OR ? Chronic renal insufficiency or renal failure; OR ? Patients who have undergone cardiac transplantation and have had no evaluation for coronary artery disease within the preceding one (1) year; OR ? Patients in whom a decision has been made to treat with interleukin 2 ? Patients awaiting solid organ transplantation who have not undergone

2019 AIM Specialty Health

78. Vascular imaging

disease 12 Arteriovenous malformation or arteriovenous fistula 12 Carotid aneurysm or dissection 12 Carotid stenosis or occlusion 12 Cerebrovascular accident or transient ischemic attack 13 Dissection – intracranial 13 Fibromuscular dysplasia 13 Hematoma 13 Hemorrhage – intracranial or subarachnoid 13 Horner’s syndrome 13 Pulsatile tinnitus 14 Stenosis or occlusion – intracranial arteries 14 Trigeminal neuralgia 14 Venous thrombosis or compression – extracranial 14 Venous thrombosis or compression (...) actions that affect clinical outcomes. Vascular Imaging Copyright © 2019. AIM Specialty Health. All Rights Reserved. 13 Cerebrovascular accident or transient ischemic attack Also see Brain Imaging guidelines. Advanced imaging is considered medically necessary for the diagnosis or management of underlying vascular pathology following transient ischemic attack or confirmed cerebrovascular accident. IMAGING STUDY - CTA or MRA brain Dissection – intracranial Advanced imaging is considered medically

2019 AIM Specialty Health

79. Hip fracture

consecutively from January 2005 to December 2010 with inclusion criteria. The total number was 138 and allocated to two groups: treated (...) with the Gamma nail (n=72,group A) and continuous skin traction (n=66,group B). Preoperative variables including patient age, gender, duration of cerebrovascular accident, duration of hypertension, ASA risk score, Harris hip score and fracture type were recorded and compared. After treatment, time of patients activity on the bed, ambulation time, Harris hip score (...) Injury in Older Adults. 2242-2250 10.1111/jgs.14439 To investigate the role of a fall risk assessment, using the Downton Fall Risk Index (DFRI), in predicting fall-related injury, fall-related head injury and hip (...) fracture , and death, in a large cohort of older women and men residing in Sweden. Cross sectional observational study. Sweden. Older adults (mean age 82.4 ± 7.8) who had a fall risk assessment using the DFRI at baseline (N = 128,596). Information on all fall-related injuries, all fall

2018 Trip Latest and Greatest

80. Baclofen

a . Please encourage all women to complete an . A corresponding patient information leaflet on is available at . Summary Baclofen is a gamma-aminobutyric acid (GABA) agonist licensed for oral (...) or intrathecal administration to alleviate voluntary muscle spasticity in patients with multiple sclerosis, spinal cord lesions, cerebral palsy, cerebrovascular accidents, traumatic head injury and meningitis. Data on the use of baclofen in human pregnancy consist of case reports and two small case series (one (...) This study is currently recruiting participants. (see ) Verified August 2016 by Denver Health and Hospital Authority Sponsor: Denver Health and Hospital (...) Withdrawal Scale (SEWS) is tool used to assess severity and is the current standard of care for both monitoring and treating AWS at Denver Health. Moderate/severe AWS (i.e., SEWS ≥ 7) has important clinical implications and requires pharmacological treatment. At present, there are no safe and effective options for preventing AWS in at-risk

2018 Trip Latest and Greatest

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