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Cerebrovascular Accident Risk in Women

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21. Intrapartum care for healthy women and babies

of/infected with HIV T oxoplasmosis – women receiving treatment Current active infection of chicken pox/rubella/genital herpes in the woman or baby Tuberculosis under treatment Immune Systemic lupus erythematosus Scleroderma Renal Abnormal renal function Renal disease requiring supervision by a renal specialist Neurological Epilepsy Myasthenia gravis Previous cerebrovascular accident Gastrointestinal Liver disease associated with current abnormal liver function tests Psychiatric Psychiatric disorder (...) of birth Choosing planned place of birth Choosing planned place of birth W Women at low risk of complications omen at low risk of complications 1.1.1 Explain to both multiparous and nulliparous women who are at low risk of complications that giving birth is generally very safe for both the woman and her baby. [2014] [2014] 1.1.2 Explain to both multiparous and nulliparous women that they may choose any birth setting (home, freestanding midwifery unit, alongside midwifery unit or obstetric unit

2014 National Institute for Health and Clinical Excellence - Clinical Guidelines

22. Effects of Dietary Sodium and Potassium Intake on Chronic Disease Outcomes and Risks

Effects of Dietary Sodium and Potassium Intake on Chronic Disease Outcomes and Risks Comparative Effectiveness Review Number 206 Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risk s eComparative Effectiveness Review Number 206 Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahrq.gov Contract No. 290-2015 (...) No. 18-EHC009-EF June 2018ii Key Messages Purpose of Review To synthesize the evidence regarding the effects of dietary sodium reduction and increased potassium intake on blood pressure and risk for cardiovascular diseases (CVD) and renal disease outcomes and related risk factors. Key Messages • Decreasing dietary sodium intake most likely reduces blood pressure in normotensive adults and more so in those with hypertension. • Higher sodium intake may be associated with greater risk for developing

2018 Effective Health Care Program (AHRQ)

23. Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks

Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks Comparative Effectiveness Review Number 206 Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risk s eComparative Effectiveness Review Number 206 Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahrq.gov Contract No. 290-2015-00010-I (...) -EHC009-EF June 2018ii Key Messages Purpose of Review To synthesize the evidence regarding the effects of dietary sodium reduction and increased potassium intake on blood pressure and risk for cardiovascular diseases (CVD) and renal disease outcomes and related risk factors. Key Messages • Decreasing dietary sodium intake most likely reduces blood pressure in normotensive adults and more so in those with hypertension. • Higher sodium intake may be associated with greater risk for developing

2018 Effective Health Care Program (AHRQ)

24. Peripheral Artery Disease and Cardiovascular Disease: Screening and Risk Assessment With the Ankle-Brachial Index

artery disease is a manifestation of atherosclerosis in the lower limbs. It can impair walking and, in severe cases, can lead to tissue loss, infection, and amputation. In addition to morbidity directly caused by PAD, patients with PAD are at increased risk for CVD events, because atherosclerosis is a systemic disease that also causes coronary and cerebrovascular events. The most recent data from the National Health and Nutrition Examination Survey (1999-2004) show that 5.9% of the US population 40 (...) % to 8% reported using it annually, and 68% reported never using it. However, the study was conducted more than a decade ago and may not reflect current practice. Assessment of Risk In addition to older age, major risk factors for PAD include diabetes, current smoking, high blood pressure, high cholesterol levels, obesity, and physical inactivity, with current smoking and diabetes showing the strongest association. Although women have a slightly lower ABI compared with men, the prevalence of low ABI

2018 U.S. Preventive Services Task Force

25. Cardiovascular Disease Risk: Screening With Electrocardiography

in addition to the evidence of clinical benefits and harms. Importance Cardiovascular disease, which encompasses atherosclerotic conditions such as coronary heart disease, cerebrovascular disease, and peripheral arterial disease, is the most common cause of death among adults in the United States. Treatment to prevent CVD events by modifying risk factors is currently informed by CVD risk assessment with tools such as the Framingham Risk Score or the Pooled Cohort Equations, which stratify individual risk (...) States. Currently, the annual incidence of new cases of myocardial infarction and cerebral vascular accident in the United States is 580,000 and 610,000, respectively. Scope of Review In 2012, the USPSTF recommended against screening for coronary heart disease with ECG in low-risk adults (D recommendation) and issued an I statement for intermediate- and high-risk adults. To update the prior recommendations, the USPSTF requested the current evidence review. , In recognition of how the field has

2018 U.S. Preventive Services Task Force

26. Le profil lipidique et glucidique des accidents vasculaires cérébraux ischémiques à Dakar Full Text available with Trip Pro

Le profil lipidique et glucidique des accidents vasculaires cérébraux ischémiques à Dakar Cerebrovascular accident (CVA) is defined as the rapid development of localized or global clinical signs of neurological dysfunction with no apparent cause other than that of vascular origin. A variety of risk factors have been identified and associated with the occurrence of Ischemic CVA, including glucose and lipid metabolism disturbances. We conducted a retrospective study at the Clinic of Neurology (...) . We here report a case series of patients between ages 10-99 years, with an average age of 67,06 years. Males were 42,55%, sex-ratio was 0,74 in favour of women. 26% of cases had impaired fasting glucose levels during the acute phase of ICVA. The lipid profile showed an increase in total cholesterol level in 52.34% of patients. Low levels of HDL cholesterol were found in 34.47% of patients. Hypertriglyceridemia was only observed in 3% of patients. LDL levels were high in 12,76% of patients

2016 The Pan African medical journal

27. Preventing and Experiencing Ischemic Heart Disease as a Woman: State of the Science Full Text available with Trip Pro

disease OR acute coronary syndrome 2. Women OR woman OR gender OR sex OR sex factors OR female OR sex difference 3. Time-to-treatment OR delay OR delayed OR time OR early diagnosis OR emergency medical services OR delayed diagnosis OR patient acceptance of health care OR therapy delay 4. Ethnic groups OR ethnicity OR racial OR race 5. Risk factors OR smoking OR hypertension OR diabetes mellitus 6. Behavior OR risk self-assessment OR cardiac risk awareness OR risk awareness OR awareness OR perception (...) for men and 55 years of age for women, the risk for IHD increases similarly in both groups. Although it has been assumed that premenopausal women (usually before 55 years of age) possess cardioprotective effects of estrogen, surprisingly, hormone replacement therapy (HRT) has not been shown to be effective in protecting against IHD in postmenopausal women and in fact may be harmful. The life expectancy for women is greater than that of men, contributing to an increased aged female population

2016 American Heart Association

28. Depression, anxiety and major adverse cardiovascular and cerebrovascular events in patients following coronary artery bypass graft surgery: a five year longitudinal cohort study Full Text available with Trip Pro

Depression, anxiety and major adverse cardiovascular and cerebrovascular events in patients following coronary artery bypass graft surgery: a five year longitudinal cohort study Although depression and anxiety have been implicated in risk for major adverse cardiovascular and cerebrovascular events (MACCE), a theoretical approach to identifying such putative links is lacking. The objective of this study was to examine the association between theoretical conceptualisations of depression (...) the self-report Mood and Anxiety Symptom Questionnaire, measuring anhedonia, anxious arousal and general distress/negative affect symptom dimensions. Incident MACCE was defined as fatal or non-fatal; myocardial infarction, unstable angina pectoris, repeat revascularization, heart failure, sustained arrhythmia, stroke or cerebrovascular accident, left ventricular failure and mortality due to cardiac causes. Time-to-MACCE was determined by hazard modelling after adjustment for EuroSCORE, smoking, body

2015 BioPsychoSocial medicine

29. Mortality of midlife women with surgically verified endometriosis-a cohort study including 2.5 million person-years of observation. (Abstract)

to this: the adjusted MRR was 0.88 (95% CI 0.81 to 0.96) for any cancer and 0.55 (95% CI 0.47 to 0.65) for cardiovascular diseases, including 0.52 (95% CI 0.42 to 0.64) for ischemic heart disease and 0.60 (95% CI 0.47 to 0.76) for cerebrovascular disease. Mortality due to alcohol, accidents and violence, respiratory, and digestive disease-related causes was also decreased.These results are limited to women with endometriosis diagnosed by surgery. In addition, the study does not extend into the oldest age groups (...) Mortality of midlife women with surgically verified endometriosis-a cohort study including 2.5 million person-years of observation. Is all-cause and cause-specific mortality increased among women with surgically verified endometriosis?The all-cause and cause-specific mortality in midlife was lower throughout the follow-up among women with surgically verified endometriosis compared to the reference cohort.Endometriosis has been associated with an increased risk of comorbidities such as certain

2019 Human Reproduction

30. Coffee consumption and mortality in Japanese men and women: A pooled analysis of eight population-based cohort studies in Japan (Japan Cohort Consortium). (Abstract)

consumption (≥5 cups/day). In men, a similar inverse association was observed for major causes of mortality except cancer. In women, coffee consumption decreased the risk for mortality due to heart disease in the 1-2 cups/day category, but increased the risk in the ≥5 cups/day category. Coffee consumption was not associated with cancer in both sexes. Results were similar among male current smokers and female never-smokers. Based on available data, this pooled analysis suggests that coffee consumption (...) Coffee consumption and mortality in Japanese men and women: A pooled analysis of eight population-based cohort studies in Japan (Japan Cohort Consortium). Coffee consumption is increasing globally. We aimed to assess the effect of coffee consumption on the risk of all-cause and cause-specific mortality in a pooled analysis of eight population-based cohort studies in Japan (Japan Cohort Consortium). Data came from eight Japanese cohort studies (144,750 men and 168,631 women). During a mean

2019 Preventive Medicine

31. Aortic Arch Width and Cardiovascular Disease in Men and Women in the Community Full Text available with Trip Pro

) examinations. The primary CVD outcome was a composite of myocardial infarction, coronary insufficiency, cerebrovascular accident, first hospitalization for heart failure, or CVD death. Cox proportional hazards models were used to estimate hazard ratio of high AAW on time-to-incident CVD after adjustment for Framingham risk factors and CAC. Net reclassification improvement was used to assess the effect of adding AAW to the baseline Framingham risk factor+CAC model. A total of 2826 participants (aged 51±11 (...) Aortic Arch Width and Cardiovascular Disease in Men and Women in the Community We sought to determine whether increased aortic arch width (AAW) adds to standard Framingham risk factors and coronary artery calcium (CAC) for prediction of incident adverse cardiovascular disease (CVD) events in community-dwelling adults.A total of 3026 Framingham Heart Study Offspring and Third Generation cohort participants underwent noncontrast multidetector computed tomography from 2002 to 2005 to quantify CAC

2018 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

32. A Biomarker Study of Palbociclib + Fulvestrant for Second, and Third Line of Postmenopausal Women With hr+/her2- Advanced Breast Cancer

(Adult, Older Adult) Sexes Eligible for Study: Female Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Women 18 years of age or older, who are either: Postmenopausal, as defined by at least one of the following criteria: Age > 60 years; Age <60 years and cessation of regular menses for at least 12 consecutive months with no alternative pathological or physiological cause; and serum estradiol and Follicle-Stimulating Hormone (FSH) level within the laboratory's reference range (...) on the mean value of the triplicate ECGs), family or personal history of long or short QT syndrome, Brugada syndrome or known history of QTc prolongation or Torsade de Pointes. any of the following within 6 months of inclusion: myocardial infarction, severe/unstable angina, ongoing cardiac dysrhythmias of NCI CTCAE Grade <2, atrial fibrillation of any grade, coronary/peripheral artery bypass graft, symptomatic congestive heart failure, cerebrovascular accident including transient ischemic attack

2018 Clinical Trials

33. Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects

pregnancy test at Screening Visit and on Day -1 of each dosing period -Note: A woman is considered of childbearing potential unless post-menopausal (> / = 1 year without menses without other known or suspected cause and with a FSH level in the menopausal range), or surgically sterilized (hysterectomy, salpingectomy, oophorectomy, or tubal ligation/occlusion). If female, not pregnant, not breast feeding, and not planning to become pregnant during the trial and for 30 days after Final Visit Females (...) participation: 1. History of acute or chronic cardiovascular disease or surgery Note: Conditions include: congestive heart failure; coronary artery disease (myocardial infarction, unstable angina); cerebrovascular disease (cerebrovascular accident or stroke or transient ischemic attack (TIA); chronic hypertension; or coronary revascularization surgery (coronary artery bypass grafting or percutaneous transluminal coronary angioplasty) 2. History of cardiac arrhythmia or syncope related to cardiac arrhythmia

2018 Clinical Trials

34. Study of AZD9833 Alone or in Combination With Palbociclib in Women With Advanced Breast Cancer

deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 130 Years (Adult, Older Adult) Sexes Eligible for Study: Female Gender Based Eligibility: Yes Gender Eligibility Description: Pre-menopausal or Post-menopausal women Accepts Healthy Volunteers: No Criteria Signed written informed consent. >= 18 years. Any (...) stenotic valve disease. Experience of any of the following procedures or conditions in the preceding 6 months: coronary artery bypass graft, angioplasty, vascular stent, myocardial infarction, unstable angina pectoris, congestive heart failure New York Heart Association (NYHA) Grade ≥2, cerebrovascular accident, or transient ischaemic attack. Uncontrolled hypertension. Hypertensive patients may be eligible but blood pressure must be adequately controlled at baseline. Patients may be re-screened

2018 Clinical Trials

35. Adjunctive Selective Estrogen Receptor Modulators on Negative and Cognitive Symptoms of Schizophrenia in Women

: take 1 placebo half an hour after breakfast every day). Hypothesis 1: Adjuvant raloxifene therapy in postmenopausal women with schizophrenia can improve negative symptoms, as measured on the rating scales, compared with the women receiving adjunctive placebo. Hypothesis 2: The cognitive function of postmenopausal female schizophrenic patients treated with raloxifene would be better than that of the placebo group. Hypothesis 3: That the Raloxifene group has less adverse reactions in postmenopausal (...) to the dysfunction of estrogen. Many studies abroad have found that estrogen and selective estrogen receptor modulators have significant effects on female patients with schizophrenia, especially on negative symptoms and cognitive functions, but the clinical application is limited due to the potential side effects of estrogen. Raloxifene is the second generation of selective estrogen receptor modulator, for the prevention and treatment of osteoporosis in postmenopausal women, which can significantly reduce

2018 Clinical Trials

36. Risk Model for Predicting Complications in Patients Undergoing Atrial Fibrillation Ablation Short Title: Risk Score for Predicting Atrial Fibrillation Ablation Complications. (Abstract)

).Patients in VC were older, likely to be white, female and had a higher prevalence of comorbidities. The overall complication rate (6.9% vs 8.3%; P < .0001) and inhospital mortality rate (0.3% vs 0.5%; P < .0001) were lower in VC than in DC. A multivariate analysis yielded 9 predictors for any complication (weightage points in parentheses): cerebrovascular accident (19), congestive heart failure (12), coagulopathy (11), renal failure (7), peripheral vascular disease (6), age ≥50 years (2), female sex (2 (...) Risk Model for Predicting Complications in Patients Undergoing Atrial Fibrillation Ablation Short Title: Risk Score for Predicting Atrial Fibrillation Ablation Complications. Predictors of complications from atrial fibrillation (AF) ablation have been identified in small studies. The combination of risk factors to predict complications after ablation has not yet been explored.The purpose of this study was to develop a risk score model that predicts complications after AF ablation.The National

2017 Heart Rhythm

37. Framingham Risk Score and Estimated 10-Year Cardiovascular Disease Risk Reduction by a Short-Term Yoga-Based Life-Style Intervention. (Abstract)

in a tertiary-care hospital. Participants with low (0 or 1 CVD risk factors) to moderately high risk (10-year risk between 10% and 20% and two or more CVD risk factors) were included. Participants with previously diagnosed CVD, defined as a history of myocardial infarction, congestive heart failure, or cerebrovascular accident, were excluded from the analysis. However, those with controlled hypertension were included. Intervention included a pretested short-term yoga-based lifestyle intervention, which (...) and cardiovascular risk factors was evaluated.Data for 554 subjects were screened, and 386 subjects (252 females) were included in the analysis. There was a significant reduction in FRS (p < 0.001) and estimated 10-year cardiovascular risk (p < 0.001) following the short-term yoga-based intervention. There was a strong positive correlation between reduction in FRS and serum total cholesterol (r = 0.60; p < 0.001). There was a moderate positive correlation between reduction in FRS and low-density lipoprotein

2017 Journal of Alternative and Complementary Medicine

38. Role of Noninvasive Testing in the Clinical Evaluation of Women With Suspected Ischemic Heart Disease Full Text available with Trip Pro

marker who is otherwise classified as being at intermediate IHD risk should be reclassified as at high IHD risk. Table 2. High IHD Clinical Risk Markers for Symptomatic Women Peripheral arterial disease Diabetes mellitus: 10-y history or poorly controlled in a woman >40 y of age Chronic obstructive lung disease Transient ischemic attacks or cerebrovascular accident Chronic kidney disease Functional disability: inability to perform activities of daily living or <5 estimated DASI METs DASI METS (...) that was updated recently in an American College of Cardiology (ACC) Foundation/AHA clinical practice guideline on detection of high-risk asymptomatic individuals. The present statement will focus on the role of diagnostic testing in the identification of symptomatic women with no, nonobstructive, and obstructive CAD and the evolutionary changes resulting in a diagnostic paradigm based on female-specific evidence to identify women at an elevated IHD risk with and without obstructive CAD who require guideline

2014 American Heart Association

39. Effect of Fibrinogen Concentrate on Intraoperative Blood Loss Among Patients With Intraoperative Bleeding During High-Risk Cardiac Surgery: A Randomized Clinical Trial. (Abstract)

accident or transient ischemic attack, renal insufficiency or failure, venous thromboembolism, pulmonary embolism, and operative complications.Among 120 patients (mean age; 71 [SD, 10] years, 37 women [31%]) included in the study, combined CABG and valve repair or replacement surgery comprised 72% of procedures and had a mean (SD) cardiopulmonary bypass time of 200 minutes (83) minutes. For the primary outcome, median blood loss in the fibrinogen group was 50 mL (interquartile range [IQR], 29-100 mL (...) Effect of Fibrinogen Concentrate on Intraoperative Blood Loss Among Patients With Intraoperative Bleeding During High-Risk Cardiac Surgery: A Randomized Clinical Trial. Fibrinogen concentrate might partly restore coagulation defects and reduce intraoperative bleeding.To determine whether fibrinogen concentrate infusion dosed to achieve a plasma fibrinogen level of 2.5 g/L in high-risk cardiac surgery patients with intraoperative bleeding reduces intraoperative blood loss.A randomized, placebo

2017 JAMA Controlled trial quality: predicted high

40. Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group

excess in utero. This may have long-term effects, particularly on female offspring. Fetal hyperandrogenism maydisturbepigeneticprogramming,inparticularthosegenes regulating reproduction and metabolism. Data in relation to the risk of miscarriage in women with PCOS are con?icting, althoughmiscarriageratesaregenerallythoughttobecompa- rable with other subfertile populations (29, 30). When pregnancy occurs in women with PCOS, there is a higher incidence of gestational diabetes (GDM) (40% to 50 (...) with PCOS (20). Conclusions(Agreement) Both amenorrheic and oligomenorrheic women may occa- sionally ovulate (level B). Menstrual cycles in women with PCOS may become more regular later in life (level B). Irregular menses are associated with increased metabolic risk (level B). The greater the menstrual irregularity, the more severe the PCOS phenotype (level B). Disagreement The time needed before regular menstrual cycles occur in young women. The extent to which irregular menses (especially amenor

2012 Society for Assisted Reproductive Technology

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