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Cerebral Spinal Fluid

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2001. Changes in cerebral artery blood flow velocity after intermittent cerebrospinal fluid drainage. (PubMed)

Changes in cerebral artery blood flow velocity after intermittent cerebrospinal fluid drainage. 8154913 1994 05 11 2018 11 13 1359-2998 70 2 1994 Mar Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. Changes in cerebral artery blood flow velocity after intermittent cerebrospinal fluid drainage. F158-9 Quinn M W MW Levene M I MI eng Comment Letter England Arch Dis Child Fetal Neonatal Ed 9501297 1359-2998 IM Arch Dis Child. 1993 Jul;69(1 Spec (...) No):74-6 8346960 Blood Flow Velocity Brain blood supply Cerebral Arteries Cerebrovascular Circulation physiology Humans Hydrocephalus therapy Infant, Newborn Spinal Puncture 1994 3 1 1994 3 1 0 1 1994 3 1 0 0 ppublish 8154913 PMC1061024 J Neurol Neurosurg Psychiatry. 1992 Apr;55(4):325-7 1583522 Arch Dis Child. 1993 Jul;69(1 Spec No):74-6 8346960 Dev Med Child Neurol. 1992 Oct;34(10):863-9 1397727

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1994 Archives of disease in childhood Fetal and neonatal edition

2002. Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid

Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Pharmacokinetic Study of a Single Dose of AVI-4126 (RESTEN-NG®) in Cerebral Spinal Fluid The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00343148 Recruitment Status : Completed First Posted : June 22, 2006 Last Update Posted : July 8, 2009 Sponsor: Sarepta Therapeutics Information

2006 Clinical Trials

2003. Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal Fluid

Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal Fluid Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal Fluid - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal Fluid The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00381433 Recruitment Status : Completed First Posted : September 27, 2006 Last Update Posted : July 8, 2009 Sponsor: Sarepta Therapeutics Information provided by: Sarepta Therapeutics

2006 Clinical Trials

2004. Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020

Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020 Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020 - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020 The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00387283 Recruitment Status : Completed First Posted : October 13, 2006 Last Update Posted : July 8, 2009 Sponsor: Sarepta Therapeutics Information provided by: Sarepta Therapeutics

2006 Clinical Trials

2005. Alterations in spinal, but not cerebral, cerebrospinal fluid Na+ concentrations affect the isoflurane minimum alveolar concentration in rats. (PubMed)

Alterations in spinal, but not cerebral, cerebrospinal fluid Na+ concentrations affect the isoflurane minimum alveolar concentration in rats. Previous studies demonstrated that MAC (the minimum alveolar concentration of an inhaled anesthetic that produces immobility in 50% of subjects exposed to noxious stimulation) for halothane directly correlates with the central nervous system concentration of Na+. However, those studies globally altered Na+ concentrations, and thus did not distinguish (...) effects on the spinal cord from cerebral effects. This is an important distinction because the cord appears to be the primary site for mediation of the immobility produced by inhaled anesthetics. Accordingly, in the present study, we examined the effect of altering intrathecal versus intracerebroventricular concentrations of Na+ on MAC.In rats prepared with chronic indwelling catheters or stylets, we infused solutions deficient in Na+ and with an excess of Na+ into the lumbar subarachnoid

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2007 Anesthesia and Analgesia

2006. Diagnostic reliability of cerebral spinal fluid tests for acute confusional state (delirium) in patients with systemic lupus erythematosus: interleukin 6 (IL-6), IL-8, interferon-alpha, IgG index, and Q-albumin. (PubMed)

Diagnostic reliability of cerebral spinal fluid tests for acute confusional state (delirium) in patients with systemic lupus erythematosus: interleukin 6 (IL-6), IL-8, interferon-alpha, IgG index, and Q-albumin. Acute confusional state (ACS) is an uncommon but severe central nervous system (CNS) syndrome in systemic lupus erythematosus (SLE) defined by clinical manifestations. To develop useful and reliable diagnostic tools for ACS, we evaluated the association of cerebral spinal fluid (CSF

2007 Journal of Rheumatology

2007. Cerebral spinal fluid pressure: effects of body position and lumbar subarachnoid drainage in a canine model. (PubMed)

Cerebral spinal fluid pressure: effects of body position and lumbar subarachnoid drainage in a canine model. This study used in vivo an model of subarachnoid cerebrospinal fluid pressure measurement.To examine the relation between subarachnoid cerebrospinal fluid pressure in the cervical and lumbar spine and varying body positions, and to test the hypothesis that increasing body inclination and lumbar subarachnoid drainage decreases cervical cerebrospinal fluid pressures.Cerebrospinal fluid (...) leaks are a recognized complication of anterior or posterior cervical surgery. Conflicting opinion exists regarding the benefits of postoperative patient positioning and lumbar subarachnoid drainage.Subarachnoid cerebrospinal fluid pressure of 7 beagles was monitored via two angiocatheters attached to pressure transducers inserted into the subarachnoid space through laminectomies at C3 and L4. Pressure measurements were taken when body position was inclined to 30 degrees, 60 degrees, and 90 degrees

2003 Spine

2008. Detection of malignant hematopoietic cells in cerebral spinal fluid previously diagnosed as atypical or suspicious. (PubMed)

Detection of malignant hematopoietic cells in cerebral spinal fluid previously diagnosed as atypical or suspicious. Involvement of the cerebrospinal fluid (CSF) by hematopoietic malignancies may be difficult to document by morphology alone. In cases with low numbers of cells or ambiguous morphology, the diagnoses of "atypical" or "suspicious" may be used. The significance of these diagnostic terms in this scenario has not been well established.Between January 2000 and July 2004, 32 patients

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2006 Cancer

2009. Testing for Antiphospholipid Antibody (aPL) Specificities in Retrospective “Normal” Cerebral Spinal Fluid (CSF) (PubMed)

Testing for Antiphospholipid Antibody (aPL) Specificities in Retrospective “Normal” Cerebral Spinal Fluid (CSF) Antiphospholipid antibodies (aPL) have been found in the blood of patients with systemic and neurological disease. The rare reports of aPL in cerebral spinal fluid (CSF) have been limited mostly to IgG and IgM anticardiolipin (aCL). Our published finding of IgA aPE in the CSF of a young stroke victim prompted us to establish "normal" CSF aPL values for a panel of aPL, which

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2004 Clinical and Developmental Immunology

2010. Accumulation of calpain and caspase-3 proteolytic fragments of brain-derived alphaII-spectrin in cerebral spinal fluid after middle cerebral artery occlusion in rats. (PubMed)

Accumulation of calpain and caspase-3 proteolytic fragments of brain-derived alphaII-spectrin in cerebral spinal fluid after middle cerebral artery occlusion in rats. Preclinical studies have identified numerous neuroprotective drugs that attenuate brain damage and improve functional outcome after cerebral ischemia. Despite this success in animal models, neuroprotective therapies in the clinical setting have been unsuccessful. Identification of biochemical markers common to preclinical (...) - and caspase-3-cleaved alphaII-SBDPs in cerebrospinal fluid (CSF) of rodents subjected to 2 hours of transient focal cerebral ischemia produced by middle cerebral artery occlusion (MCAO) followed by reperfusion. After MCAO injury, full-length alphaII-spectrin protein was decreased in brain tissue and increased in CSF from 24 to 72 hours after injury. Whereas alphaII-SBDPs were undetectable in sham-injured control animals, calpain but not caspase-3 specific alphaII-SBDPs were significantly increased in CSF

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2004 Journal of Cerebral Blood Flow and Metabolism

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