How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

9,770 results for

Cerebral Aneurysm

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Primary Cilia Deficiency Induces Intracranial Aneurysm Full Text available with Trip Pro

Primary Cilia Deficiency Induces Intracranial Aneurysm Intracranial aneurysm (IA) rupture is life-threatening. However, the mechanisms underlying IA initiation, progression, and rupture remain poorly understood. In the present study, we examined the role of primary cilia in IA development.IA was experimentally induced in mice with elastase and angiotensin II treatment. The number of cells with primary cilia was determined in both IA and peri-IA regions. The role of primary cilia in IA

2018 Shock (Augusta, Ga.)

182. Correlating Clinical Risk Factors and Histological Features in Ruptured and Unruptured Human Intracranial Aneurysms: The Swiss AneuX Study Full Text available with Trip Pro

Correlating Clinical Risk Factors and Histological Features in Ruptured and Unruptured Human Intracranial Aneurysms: The Swiss AneuX Study Pathogenesis of intracranial aneurysm is complex and the precise biomechanical processes leading to their rupture are uncertain. The goal of our study was to characterize the aneurysmal wall histologically and to correlate histological characteristics with clinical and radiological factors used to estimate the risk of rupture. A new biobank of aneurysm domes (...) resected at the Geneva University Hospitals (Switzerland) was used. Histological analysis revealed that unruptured aneurysms have a higher smooth muscle cell (SMC) content and a lower macrophage content than ruptured domes. These differences were associated with more collagen in unruptured samples, whereas the elastin content was not affected. Collagen content and type distribution were different between thick and thin walls of unruptured aneurysms. Classification of aneurysm domes based

2018 Journal of neuropathology and experimental neurology

183. Focused opening of the Sylvian fissure for the management of middle cerebral artery aneurysms Full Text available with Trip Pro

Focused opening of the Sylvian fissure for the management of middle cerebral artery aneurysms A wide opening of the Sylvian fissure (SF) regarding the treatment of middle cerebral artery (MCA) aneurysm allows us to ensure early proximal control by the proximal start of Sylvian dissection and enough comfort for the microsurgical manipulation and aneurysm clipping. However, major mechanical manipulation of arteries associated with blood oozing into the surgical field may increase the incidence (...) for a proper focused SF opening. A patient with an MCA bifurcation aneurysm is placed in supine position. The head elevated 20 cm above the cardiac level is slightly extended, rotated to the contralateral side, and tilted laterally. A lateral supraorbital approach is performed. After cerebrospinal fluid release and under high magnification, the opening place of the SF is identified. Thus, 10-15 mm opening is made with a sharp needle followed by microscissors. Under a keyhole concept, the M1 segment

2018 Surgical neurology international

184. Prediction of Thin-Walled Areas of Unruptured Cerebral Aneurysms through Comparison of Normalized Hemodynamic Parameters and Intraoperative Images Full Text available with Trip Pro

Prediction of Thin-Walled Areas of Unruptured Cerebral Aneurysms through Comparison of Normalized Hemodynamic Parameters and Intraoperative Images Rupture of a cerebral aneurysm occurs mainly in a thin-walled area (TWA). Prediction of TWAs would help to assess the risk of rupture and select appropriate treatment strategy. There are several limitations of current prediction techniques for TWAs. To predict TWAs more accurately, HP should be normalized to minimize the influence of analysis (...) conditions, and the effectiveness of normalized, combined hemodynamic parameters (CHPs) should be investigated with help of the quantitative color analysis of intraoperative images.A total of 21 unruptured cerebral aneurysms in 19 patients were analyzed. A normalized CHP was newly suggested as a weighted average of normalized wall shear stress (WSS) and normalized oscillatory shear index (OSI). Delta E from International Commission on Illumination was used to more objectively quantify color differences

2018 BioMed research international

185. Surgical strategy for an adult patient with a catecholamine-producing ganglioneuroblastoma and a cerebral aneurysm: a case report Full Text available with Trip Pro

Surgical strategy for an adult patient with a catecholamine-producing ganglioneuroblastoma and a cerebral aneurysm: a case report Ganglioneuroblastomas, particularly those that produce catecholamine, are extremely rare in adults. Here, we report an interesting surgical case of an adult patient with a catecholamine-producing ganglioneuroblastomas in her adrenal gland, suspected to be a pheochromocytoma, and with a cerebral aneurysm.The patient was a 73-year-old woman under treatment (...) . She was, therefore, diagnosed with a pheochromocytoma and scheduled for tumor resection. However, preoperatively, 8-mm-diameter cerebral aneurysm was incidentally found in her basilar artery. This required careful preoperative discussion. The aneurysm was difficult to approach and treat, and based on its position, shape, and size, the risk of rupture was low. Because hypertension is a major risk factor for aneurysmal rupture, we decided to proceed with the tumor resection. A lumbar catheter

2018 Surgical Case Reports

186. Numerical simulation of patient-specific endovascular stenting and coiling for intracranial aneurysm surgical planning Full Text available with Trip Pro

Numerical simulation of patient-specific endovascular stenting and coiling for intracranial aneurysm surgical planning In this study, we develop reliable and practical virtual coiling and stenting methods for intracranial aneurysm surgical planning. Since the purpose of deploying coils and stents is to provide device geometries for subsequent accurate post-treatment computational fluid dynamics analysis, we do not need to accurately capture all the details such as the stress and force (...) of surgical planning process.The stent was delivered to the suitable position during the clinical treatment, achieving good expansion and apposition of the stent to the arterial wall. The coil was deployed into the aneurysm sac and deformed to different shapes because of the stored strain energy during coil package process and the direction of the microcatheter.The method which we develop here could become surgical planning for intracranial aneurysm treatment in the clinical workflow.

2018 Journal of translational medicine

187. Analysis of the influence of imaging-related uncertainties on cerebral aneurysm deformation quantification using a no-deformation physical flow phantom Full Text available with Trip Pro

Analysis of the influence of imaging-related uncertainties on cerebral aneurysm deformation quantification using a no-deformation physical flow phantom Cardiac-cycle related pulsatile aneurysm motion and deformation is assumed to provide valuable information for assessing cerebral aneurysm rupture risk. Accordingly, numerous studies addressed quantification of cerebral aneurysm wall motion and deformation. Most of them utilized in vivo imaging data, but image-based aneurysm deformation (...) using different modalities [MRI, CT, 3D-RA] and mimicking physiologically realistic flow conditions. Resulting image data was analyzed by an established registration-based approach for automated wall motion quantification. The data reveals severe dependency between contrast media inflow-related image intensity changes and the extent of estimated wall deformation. The study illustrates that imaging-related uncertainties affect the accuracy of cerebral aneurysm deformation quantification, suggesting

2018 Scientific reports

188. The role of inflammation and potential use of sex steroids in intracranial aneurysms and subarachnoid hemorrhage Full Text available with Trip Pro

The role of inflammation and potential use of sex steroids in intracranial aneurysms and subarachnoid hemorrhage Aneurysmal subarachnoid hemorrhage (aSAH) continues to be a devastating neurological condition with a high risk of associated morbidity and mortality. Inflammation has been shown to increase the risk of complications associated with aSAH such as vasospasm and brain injury in animal models and humans. The goal of this review is to discuss the inflammatory mechanisms of aneurysm (...) formation, rupture and vasospasm and explore the role of sex hormones in the inflammatory response to aSAH.A literature review was performed using PubMed using the following search terms: "intracranial aneurysm," "cerebral aneurysm," "dihydroepiandrosterone sulfate" "estrogen," "hormone replacement therapy," "inflammation," "oral contraceptive," "progesterone," "sex steroids," "sex hormones" "subarachnoid hemorrhage," "testosterone." Only studies published in English language were included

2018 Surgical neurology international

189. A giant partially thrombosed, partially filling, and partially calcified intracranial aneurysm Full Text available with Trip Pro

A giant partially thrombosed, partially filling, and partially calcified intracranial aneurysm 30105133 2018 08 14 2229-5097 9 2018 Surgical neurology international Surg Neurol Int A giant partially thrombosed, partially filling, and partially calcified intracranial aneurysm. 139 10.4103/sni.sni_97_18 Singla Navneet N Department of Neurosurgery, PGIMER, Chandigarh, India. Aggarwal Ashish A Department of Neurosurgery, PGIMER, Chandigarh, India. eng Journal Article 2018 07 24 India Surg Neurol

2018 Surgical neurology international

190. Author Correction: Higher leukocyte count predicts 3-month poor outcome of ruptured cerebral aneurysms Full Text available with Trip Pro

Author Correction: Higher leukocyte count predicts 3-month poor outcome of ruptured cerebral aneurysms A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

2018 Scientific reports

191. Novel microguidewire-assist (MGA) manoeuver for coil embolisation of an unruptured middle cerebral artery aneurysm Full Text available with Trip Pro

Novel microguidewire-assist (MGA) manoeuver for coil embolisation of an unruptured middle cerebral artery aneurysm We describe here a novel yet very simple technique, called microguidewire-assist (MGA) manoeuvre, for coil embolisation of unruptured intracranial aneurysms. A 79-year-old woman with a small, broad-necked middle cerebral artery (MCA) bifurcation aneurysm that incorporated the orifice of the acute-angled M2 superior trunk underwent coil embolisation. Since the balloon assist (...) technique was not feasible, we inserted and retained only the microguidewire through M1 to the M2 superior trunk; subsequently, with appropriate use of the microguidewire, coil embolisation was completed. The MGA manoeuvre resulted in slight vessel straightening and subsequent changes in the angulation of the aneurysmal neck, with which stable placement of the platinum coil was successfully accomplished. For coil embolisation of small, broad-necked MCA aneurysms that partially straddle the M2 trunk

2018 BMJ case reports

192. The dental infections in patients undergoing preoperative dental examination before surgical treatment of saccular intracranial aneurysm Full Text available with Trip Pro

The dental infections in patients undergoing preoperative dental examination before surgical treatment of saccular intracranial aneurysm Dental bacterial DNA and bacterial-driven inflammation markers have previously been detected in intracranial aneurysm tissue samples. This study aimed (i) to assess the possible presence of dental infectious foci, (ii) and the possible association between typical odontogenic bacteria and clinical dental findings in patients undergoing pre-operative dental (...) examination before surgical treatment of saccular intracranial aneurysm. Ninety patients with an intracranial aneurysm were recruited to the study, and the patients' teeth were routinely investigated. Clinical data and bacterial samples from the gingival pockets were collected from a subpopulation of 60 patients. Five typical dental pathogens and total bacteria amounts were measured from gingival samples using real-time quantitative PCR.The amounts of total bacterial and Fusobacterium nucleatum DNA were

2018 BMC research notes

193. Electroacupuncture Improves Cerebral Vasospasm and Functional Outcome of Patients With Aneurysmal Subarachnoid Hemorrhage Full Text available with Trip Pro

Electroacupuncture Improves Cerebral Vasospasm and Functional Outcome of Patients With Aneurysmal Subarachnoid Hemorrhage Cerebral vasospasm is the major cause of a poor outcome after aneurysmal subarachnoid hemorrhage (aSAH), and effective treatments for vasospasm are limited. The purpose of this study was to research the impact of electroacupuncture (EA) on cerebral vasospasm and the outcomes of patients with aSAH. A total of 60 age- and sex-matched aSAH patients were collected from Ningbo (...) First Hospital between December 2015 and June 2017. All patients were given a basic treatment of nimodipine and randomized into two groups. The study group was treated with EA therapy on the Baihui (GV20) acupoint, and the control group was given mock transcutaneous electrical nerve stimulation. Cerebral vasospasm was measured by computed tomographic perfusion (CTP) and transcranial doppler (TCD). The mean flow velocity (MFV) in the middle cerebral artery (MCA), cerebral blood flow (CBF), cerebral

2018 Frontiers in neuroscience Controlled trial quality: uncertain

194. Mycotic Cerebral Aneurysms Secondary to Scedosporium Prolificans Infection in a Patient with Multiple Sclerosis Full Text available with Trip Pro

Mycotic Cerebral Aneurysms Secondary to Scedosporium Prolificans Infection in a Patient with Multiple Sclerosis 30284775 2018 11 14 1738-6586 14 4 2018 Oct Journal of clinical neurology (Seoul, Korea) J Clin Neurol Mycotic Cerebral Aneurysms Secondary to Scedosporium Prolificans Infection in a Patient with Multiple Sclerosis. 601-603 10.3988/jcn.2018.14.4.601 Guadalajara M Cristina Valencia MCV Department of Neurology, University General Hospital, Ciudad Real, Spain. mavagua_24@hotmail.com

2018 Journal of clinical neurology (Seoul, Korea)

195. Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature Full Text available with Trip Pro

Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature Methamphetamine or "meth" is a sympathomimetic amine of the amphetamine-type substances (ATS) class with an extremely high potential for abuse. Illicitly abused neurostimulants like cocaine and meth predispose patients to the aneurysmal formation with reported rupture at a younger age and in much smaller sized aneurysms. However, very rapid growth of aneurysm within less than 2 weeks (...) and therefore warrants careful consideration and close monitoring. This case confirms the dynamic temporal effects of methamphetamine use on intracranial vessels and this specific neurostimulants association to rapid aneurysmal formation. In light of vascular pathologies the possibility of drug-induced pseudoaneurysm should also be considered in young patients with history of meth abuse.

2018 Case reports in neurological medicine

196. Duplicated middle cerebral artery associated with aneurysm at M1/M2 bifurcation: a case report Full Text available with Trip Pro

Duplicated middle cerebral artery associated with aneurysm at M1/M2 bifurcation: a case report A duplicated middle cerebral artery arises from the internal carotid artery and supplies blood to the middle cerebral artery territory. A duplicated middle cerebral artery is sometimes associated with an intracranial aneurysm. Most aneurysms associated with duplicated middle cerebral artery are located at the origin of the duplicated middle cerebral artery. An aneurysm located at the distal middle (...) cerebral artery is not common.We encountered a 62-year-old Asian man with duplicated middle cerebral artery associated with aneurysms at the M1/M2 junction of the duplicated middle cerebral artery and top of the internal carotid artery.In cases of duplicated middle cerebral artery, association with a distal aneurysm on the duplicated middle cerebral artery is rare. However, the aneurysm may be formed on the thicker middle cerebral artery due to hemodynamic stress.

2018 Journal of medical case reports

197. Intracranial Mirror Aneurysms: Anatomic Characteristics and Treatment Options Full Text available with Trip Pro

Intracranial Mirror Aneurysms: Anatomic Characteristics and Treatment Options Mirror aneurysms are generally considered as a subset of multiple aneurysms, defined as aneurysms occurring bilaterally and symmetrically on the same-named vessels. Although not infrequent, the characteristics of mirror aneurysms are not well studied. This investigation was conducted to elucidate the anatomic features of such lesions and examine treatment options.A retrospective review was conducted, aimed at 172 (...) patients treated for 344 mirror aneurysms between January 2007 and December 2015. Aneurysms of similar nature but in asymmetric locations on the same-named vessels were excluded. All available records were examined and lesion characteristics, as well as treatment outcomes were assessed.In study subjects (n = 172), mirror aneurysms most often involved middle cerebral artery bifurcation (n = 83), followed by a paraclinoid internal carotid artery (n = 50) and posterior communicating artery (n = 21). Most

2018 Korean Journal of Radiology

198. A pilot study on assessing the role of intra-operative Flow 800 vascular map model in predicting onset of vasospasm following micro vascular clipping of ruptured intracranial aneurysms Full Text available with Trip Pro

A pilot study on assessing the role of intra-operative Flow 800 vascular map model in predicting onset of vasospasm following micro vascular clipping of ruptured intracranial aneurysms Objective To ascertain the predictive value of intra-operative FLOW 800 vascular map model in predicting onset of post-operative clinical vasospasm and delayed cerebral ischemia among patients undergoing micro-vascular clipping of ruptured intracranial aneurysms.  Material and methods A total of 40 patients were (...) enrolled in the study and their variables such as age, World Federation of Neurological Surgeons (WFNS) grade at presentation, Computerized Tomography (CT) Fisher grading, location of the aneurysms, and Indocyanine Green (ICG) flow status were compared and statistically analyzed along with differences in Absorption Intensities (AI) and difference in time lag values obtained from the FLOW 800 vascular map studies for predicting onset of vasospasm.  Results The Receiver Operating curve (ROC) of the model

2018 F1000Research

199. A Highly Automated Computational Method for Modeling of Intracranial Aneurysm Hemodynamics Full Text available with Trip Pro

A Highly Automated Computational Method for Modeling of Intracranial Aneurysm Hemodynamics Intracranial aneurysms manifest in a vast variety of morphologies and their growth and rupture risk are subject to patient-specific conditions that are coupled with complex, non-linear effects of hemodynamics. Thus, studies that attempt to understand and correlate rupture risk to aneurysm morphology have to incorporate hemodynamics, and at the same time, address a large enough sample size so as to produce (...) reliable statistical correlations. In order to perform accurate hemodynamic simulations for a large number of aneurysm cases, automated methods to convert medical imaging data to simulation-ready configuration with minimal (or no) human intervention are required. In the present study, we develop a highly-automated method based on the immersed boundary method framework to construct computational models from medical imaging data which is the key idea is the direct use of voxelized contrast information

2018 Frontiers in physiology

200. Microsurgical clipping for anterior communicating artery aneurysm associated with the accessory anterior cerebral artery via the pterional approach Full Text available with Trip Pro

Microsurgical clipping for anterior communicating artery aneurysm associated with the accessory anterior cerebral artery via the pterional approach Accessory anterior cerebral artery (ACA), a type of median artery of anomalous triplicate ACA, is not rare, but aneurysms of the anterior communicating artery (ACoA) associated with accessory ACA can be a considerable challenge to treat surgically based on the morphological features of the ACoA complex.A 35-year-old man was admitted to our hospital (...) with severe headache and subsequent loss of consciousness. Initial computed tomography (CT) showed typical findings of subarachnoid hemorrhage in the basal cistern and three-dimensional CT angiography revealed an ACoA aneurysm arising from the trifurcation of the accessory ACA, the branching point of the ACoA, and the right A1 or A2 segment of the ACA. The aneurysmal fundus projected superolaterally to the right, and was treated via a right-sided pterional approach. The aneurysm was behind the ipsilateral

2018 Surgical neurology international

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>