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Cerebral Ventricle

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1. Lateral ventricle volume trajectories predict response inhibition in older age-A longitudinal brain imaging and machine learning approach. Full Text available with Trip Pro

Lateral ventricle volume trajectories predict response inhibition in older age-A longitudinal brain imaging and machine learning approach. In a three-wave 6 yrs longitudinal study we investigated if the expansion of lateral ventricle (LV) volumes (regarded as a proxy for brain tissue loss) predicts third wave performance on a test of response inhibition (RI).Trajectories of left and right lateral ventricle volumes across the three waves were quantified using the longitudinal stream (...) level (p = 0.014). 56% of the fast performers were successfully classified. All these were females, and typically older than 65 yrs at inclusion. For the true slow performers, those being correctly classified had higher LVVs than those being misclassified, and their ages at inclusion were also higher.Major contributions were: (i) a longitudinal design, (ii) advanced brain imaging and segmentation procedures with longitudinal data analysis, and (iii) a data driven machine learning approach including

2019 PLoS ONE

2. Brain abnormalities in cognition, anxiety, and depression regulatory regions in adolescents with single ventricle heart disease Full Text available with Trip Pro

Brain abnormalities in cognition, anxiety, and depression regulatory regions in adolescents with single ventricle heart disease Single ventricle heart disease (SVHD) adolescents show cognitive impairments and anxiety and depressive symptoms, indicating the possibility of brain injury in regions that control these functions. However, brain tissue integrity in cognition, anxiety, and depression regulatory sites in SVHD remains unclear. We examined brain tissue changes in SVHD compared to controls (...) : 19/17). Whole-brain T2-relaxation maps were calculated, normalized to a common space, smoothed, and compared between groups and sexes (analysis of covariance; covariates: age, sex; p < 0.001).SVHD subjects showed significantly increased BAI and PHQ-9 and reduced MoCA and WRAML2 scores over controls. Several brain regions in SVHD showed increased T2-relaxation values (chronic injury), including the cingulate, and insula, hippocampus/para-hippocampal gyrus, thalamus, hypothalamus, amygdala, frontal

2018 Journal of Neuroscience Research

3. The role of radiosurgery in the acute management of fourth ventricle compression due to brain metastases Full Text available with Trip Pro

The role of radiosurgery in the acute management of fourth ventricle compression due to brain metastases Approximately 20-30% of all intracranial metastases are located in the posterior fossa. The clinical evolution hinges on factors such as tumor growth dynamics, local topographic conditions, performance status, and prompt intervention. Fourth ventricle (V4) compression with secondary life-threatening obstructive hydrocephalus remains a major concern, often requiring acute surgical

2018 Surgical neurology international

4. CSF in the ventricles of the brain behaves as a relay medium for arteriovenous pulse wave phase coupling. Full Text available with Trip Pro

CSF in the ventricles of the brain behaves as a relay medium for arteriovenous pulse wave phase coupling. The ventricles of the brain remain perhaps the largest anatomic structure in the human body without established primary purpose, even though their existence has been known at least since described by Aristotle. We hypothesize that the ventricles help match a stroke volume of arterial blood that arrives into the rigid cranium with an equivalent volume of ejected venous blood by spatially (...) configuring cerebrospinal fluid (CSF) to act as a low viscosity relay medium for arteriovenous pulse wave (PW) phase coupling. We probe the hypothesis by comparing the spatiotemporal behavior of vascular PW about the ventricular surfaces in piglets to internal observations of ventricle wall motions and adjacent CSF pressure variations in humans. With wavelet brain angiography data obtained from piglets, we map the travel relative to brain pulse motion of arterial and venous PWs over the ventricle surfaces

2017 PLoS ONE

5. The 3<sup>rd</sup> ventricle of the human fetal brain: normative data and pathologic correlation. A 3D transvaginal neurosonography study. Full Text available with Trip Pro

The 3rd ventricle of the human fetal brain: normative data and pathologic correlation. A 3D transvaginal neurosonography study. The objective of the study are to describe (a) the technical aspects and (b) the anatomical boundaries of the fetal third ventricle (3V) on the midsagittal sonographic view and to assess (c) different biometric parameters in normal and abnormal fetuses and (d) and their reproducibility.This study included 67 normal and 50 CNS anomalies fetuses which include (...) /WA are significantly different between normal fetuses and the SVM (P ≤ .001). Interthalamic adhesion diameter of ≤7.1 mm is able to identify SVM with 98.6% accuracy (CI: 0.92-0.99). In ACC cases, the AP diameter is significantly shorter than both normal fetuses and ventriculomegaly. Intraobserver/interobserver reliability was good for most variables.Transvaginal neurosonography enables visualization of the normal and abnormal fetal third ventricle. An ITAD <7.1 identifies aqueductal stenosis

2018 Prenatal diagnosis

6. Fetuses with Single Ventricle Congenital Heart Disease Manifest Impairment of Regional Brain Growth. (Abstract)

Fetuses with Single Ventricle Congenital Heart Disease Manifest Impairment of Regional Brain Growth. Anomalous neurological development associated with congenital heart disease (CHD) has been reported as early as third trimester of fetal development. While several studies have characterized variations in CHD neurodevelopmental outcomes in early childhood, these reports are often confounded by postnatal factors such as surgical outcome. Recent studies have focused on the comparing neurological (...) variations between fetuses with CHD and normal controls. In this work, we present a comparison of in utero variations in brain development between fetuses with different types of CHD, by analyzing them under categories of single ventricle versus biventricular cardiac anatomy.Using recent advances in fetal magnetic resonance imaging (MRI), we quantify the volumetric trajectories of various brain tissues (such as cortical plate, developing white matter, cerebrospinal fluid [CSF], and cerebellum).Our study

2018 Prenatal diagnosis

7. Comparison between Brain Computed Tomography Scan and Transcranial Sonography to Evaluate Third Ventricle Width, Peri-Mesencephalic Cistern, and Sylvian Fissure in Traumatic Brain-Injured Patients Full Text available with Trip Pro

Comparison between Brain Computed Tomography Scan and Transcranial Sonography to Evaluate Third Ventricle Width, Peri-Mesencephalic Cistern, and Sylvian Fissure in Traumatic Brain-Injured Patients Transcranial color-coded duplex sonography (TCCS) may help guide multimodal monitoring in the neurocritical setting. It may provide indirect information about intracranial hypertension, such as midline shift, third ventricle width, and peri-mesencephalic cistern obliteration. We aim to assess (...) Score 5 [4,6]). The mean difference between the brain CT scan and TCCS in measuring the midline shift was 0.30 ± 2.1 mm (intraclass correlation coefficient: 0.93; p < 0.01). An excellent correlation was also observed between the methods in assessing the third ventricle width (intraclass correlation coefficient: 0.88; p < 0.01). Bland-Altman plots did not show any systematic bias in either agreement analysis. TCCS showed good accuracy in predicting non-compressed peri-mesencephalic cisterns (AUC

2017 Frontiers in neurology

8. Migration of lipiodol into lateral ventricles after embolization of cerebral arteriovenous malformation: a case report. (Abstract)

Migration of lipiodol into lateral ventricles after embolization of cerebral arteriovenous malformation: a case report. N-butyl cyanoacrylate (NBCA) has been used to embolise brain arteriovenous malformations (AVMs) for over 30 years. It is a mixed with lipiodol in varying proportions. We report a 22-year-old male with intraventricular hemorrhage from a ruptured intranidal AVM aneurysm in the left temporal lobe. The intranidal aneurysm and the nidus were successfully embolized using a 20% NBCA (...) and lipiodol mixture without any complications according to computed tomography (CT) immediately after treatment. Scattered high-density spots were observed in both lateral ventricles on CT 5 days after embolization, suggesting migration of lipiodol. We speculated that the aneurysm was a pseudoaneurysm whose wall protruded into the inferior horn of the left lateral ventricle, and the lipiodol in the NBCA migrated into the ventricles after the thin part of the wall ruptured. The patient developed pyrexia

2019 British Journal of Neurosurgery

9. Reduction of brain volumes after neonatal cardiopulmonary bypass surgery in single ventricle congenital heart disease prior to Fontan completion. Full Text available with Trip Pro

Reduction of brain volumes after neonatal cardiopulmonary bypass surgery in single ventricle congenital heart disease prior to Fontan completion. BackgroundLittle is known about the relationship between brain volumes and neurodevelopmental outcome at 2 years of age in children with single-ventricle congenital heart disease (CHD). We hypothesized that reduced brain volumes may be associated with adverse neurodevelopmental outcome.MethodsVolumetric segmentation of cerebral magnetic resonance (...) in patients compared with controls (GM: P=0.017, deep GM: P=0.012, and WM: P=0.015), whereas CSF volumes were greater (P=0.014). Of all intracranial volumes, only CSF volume was associated with neurodevelopmental outcome, accounting for 21% (P=0.011) of variability in the cognitive composite score when combined with common risk factors in a multivariable analysis.ConclusionIncreased CSF volume represents a significant risk factor for neurodevelopmental impairment in children with single-ventricle CHD

2017 Pediatric Research

10. Brain Tumor in an In Vitro Fertilization–Facilitated Pregnancy: Fourth Ventricle Anaplastic Ependymoma in the Second Trimester Full Text available with Trip Pro

Brain Tumor in an In Vitro Fertilization–Facilitated Pregnancy: Fourth Ventricle Anaplastic Ependymoma in the Second Trimester We present a case of fourth ventricle anaplastic ependymoma in a pregnancy which was the first result of three rounds of in vitro fertilization (IVF) and embryo transfer. Whether hormonal treatment can directly or indirectly precipitate brain tumors to develop or become symptomatic is unclear.

2016 Journal of neurological surgery reports

11. Objective Ventricle Segmentation in Brain CT with Ischemic Stroke Based on Anatomical Knowledge Full Text available with Trip Pro

Objective Ventricle Segmentation in Brain CT with Ischemic Stroke Based on Anatomical Knowledge Ventricle segmentation is a challenging technique for the development of detection system of ischemic stroke in computed tomography (CT), as ischemic stroke regions are adjacent to the brain ventricle with similar intensity. To address this problem, we developed an objective segmentation system of brain ventricle in CT. The intensity distribution of the ventricle was estimated based on clustering (...) technique, connectivity, and domain knowledge, and the initial ventricle segmentation results were then obtained. To exclude the stroke regions from initial segmentation, a combined segmentation strategy was proposed, which is composed of three different schemes: (1) the largest three-dimensional (3D) connected component was considered as the ventricular region; (2) the big stroke areas were removed by the image difference methods based on searching optimal threshold values; (3) the small stroke regions

2017 BioMed research international

12. Alcohol consumption impairs the ependymal cilia motility in the brain ventricles Full Text available with Trip Pro

Alcohol consumption impairs the ependymal cilia motility in the brain ventricles Ependymal cilia protrude into the central canal of the brain ventricles and spinal cord to circulate the cerebral spinal fluid (CSF). Ependymal cilia dysfunction can hinder the movement of CSF leading to an abnormal accumulation of CSF within the brain known as hydrocephalus. Although the etiology of hydrocephalus was studied before, the effects of ethanol ingestion on ependymal cilia function have not been (...) investigated in vivo. Here, we report three distinct types of ependymal cilia, type-I, type-II and type-III classified based upon their beating frequency, their beating angle, and their distinct localization within the mouse brain-lateral ventricle. Our studies show for the first time that oral gavage of ethanol decreased the beating frequency of all three types of ependymal cilia in both the third and the lateral rat brain ventricles in vivo. Furthermore, we show for the first time that hydin

2017 Scientific reports

13. mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis Full Text available with Trip Pro

mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis Radial glial cells (RCGs) are self-renewing progenitor cells that give rise to neurons and glia during embryonic development. Throughout neurogenesis, these cells contact the cerebral ventricles and bear a primary cilium. Although the role of the primary cilium in embryonic patterning has been studied, its role in brain ventricular morphogenesis is poorly characterized. Using conditional mutants, we show (...) that the primary cilia of radial glia determine the size of the surface of their ventricular apical domain through regulation of the mTORC1 pathway. In cilium-less mutants, the orientation of the mitotic spindle in radial glia is also significantly perturbed and associated with an increased number of basal progenitors. The enlarged apical domain of RGCs leads to dilatation of the brain ventricles during late embryonic stages (ventriculomegaly), which initiates hydrocephalus during postnatal stages

2017 Development (Cambridge, England)

14. Efficacy of intravenous plus intrathecal/intracerebral ventricle injection of polymyxin B for post-neurosurgical intracranial infections due to MDR/XDR Acinectobacter baumannii: a retrospective cohort study Full Text available with Trip Pro

Efficacy of intravenous plus intrathecal/intracerebral ventricle injection of polymyxin B for post-neurosurgical intracranial infections due to MDR/XDR Acinectobacter baumannii: a retrospective cohort study Post-neurosurgical intracranial infections caused by multidrug-resistant or extensively drug-resistant Acinetobacter baumannii are difficult to treat and associated with high mortality. In this study, we analyzed the therapeutic efficacy of intravenous combined with intrathecal/intracerebral (...) ventricle injection of polymyxin B for this type of intracranial infection.This retrospective study was conducted from January 2013 to September 2017 at the Second Affiliated Hospital, Zhejiang University School of Medicine (Hangzhou,China) and included 61 cases for which cerebrospinal fluid (CSF) cultures were positive for multidrug-resistant or extensively drug-resistant A. baumannii after a neurosurgical operation. Patients treated with intravenous and intrathecal/intracerebral ventricle injection

2018 Antimicrobial resistance and infection control

15. Traumatic Brain Injury and Dementia

features to dementia – such as memory disturbances, behavior and personality changes, and Parkinsonism – but is currently thought to be a distinct clinical entity with a distinct pattern of brain pathology detectable upon autopsy, 19 including atrophy in the frontal and temporal lobes, widened ventricles, dilated and bifurcated septum pellucidums, and accumulation of proteins such as tau. 20 Research on CTE to date primarily focuses on autopsy examinations, which is outside of this scope of this report (...) Traumatic Brain Injury and Dementia 4 February 2019 Prepared for: Department of Veterans Affairs Veterans Health Administration Health Services Research & Development Service Washington, DC 20420 Prepared by: Evidence Synthesis Program (ESP) Coordinating Center Portland VA Health Care System Portland, OR Mark Helfand, MD, MPH, MS, Director Evidence Brief: Traumatic Brain Injury and Dementia Authors: Kim Peterson, MS Stephanie Veazie, MPH Donald Bourne, MPH Johanna Anderson, MPH Evidence

2019 Veterans Affairs Evidence-based Synthesis Program Reports

16. Effect of Skull Type on the Relative Size of Cerebral Cortex and Lateral Ventricles in Dogs Full Text available with Trip Pro

Effect of Skull Type on the Relative Size of Cerebral Cortex and Lateral Ventricles in Dogs Volume measurements of the brain are of interest in the diagnosis of brain pathology. This is particularly so in the investigation hydrocephalus and canine cognitive dysfunction (CCD), both of which result in thinning of the cerebral cortex and enlarged ventricles. Volume assessment can be made using computed tomography or more usually magnetic resonance imaging (MRI). There is, however, some uncertainty (...) cranial cavity dimension) had a smaller ratio of cortical to ventricular volume (low C:V ratio) than breeds with lower CrI skull types. It is important to consider this effect of skull shape on the relative volume estimates of the cerebral cortex and ventricles when trying to establish if pathology is present.

2017 Frontiers in veterinary science

17. A case of a cerebral cavernous malformation of the third ventricle that caused the syndrome of inappropriate secretion of antidiuretic hormone Full Text available with Trip Pro

A case of a cerebral cavernous malformation of the third ventricle that caused the syndrome of inappropriate secretion of antidiuretic hormone Cerebral cavernous malformations (CCMs, also known as cavernous hemanigiomas) of the third ventricle are uncommon. Here, we present a rare case of a CCM that caused the syndrome of inappropriate secretion of antidiuretic hormone (SIADH).A 68-year-old man presented with acute-onset cognitive and memory disturbance. Endocrinological examinations revealed (...) hyponatremia due to SIADH. Computed tomography indicated a high-density mass in the third ventricle that caused left unilateral hydrocephalus due to obstruction of the foramen Monroe. On magnetic resonance imaging, the mass showed high intensity in both T1 and T2-weighted images and low intensity in susceptibility-weighted images, suggesting subacute intralesional hemorrhage. We completely excised the mass via a basal interhemispheric translamina terminalis approach. Intraoperatively, the mass adhered

2017 Surgical neurology international

18. Ventricular access device placement in the fourth ventricle to treat malignant fourth ventricle brain tumors: technical note Full Text available with Trip Pro

Ventricular access device placement in the fourth ventricle to treat malignant fourth ventricle brain tumors: technical note Ventricular access devices (VADs) are commonly placed in the lateral ventricle but rarely placed in other ventricular compartments. This manuscript describes technical aspects of VAD placement into the fourth ventricle for the purpose of treating malignant posterior fossa brain tumors.As part of a pilot clinical trial to treat recurrent malignant brain tumors in children (...) , seven patients underwent posterior fossa craniotomy and placement of a ventricular catheter under direct vision into the fourth ventricle. The catheter was placed without passing through any brain parenchyma. It was then connected to a VAD placed subcutaneously at the inferior aspect of the incision. Three of the seven patients underwent simultaneous subtotal resection of recurrent tumor located in the fourth ventricle or cerebellum, and one patient underwent simultaneous tumor biopsy. The VAD

2015 Child's Nervous System

19. Appropriate Use Criteria: Imaging of the Brain

of the Guidelines 4 Administrative Guidelines 5 Ordering of Multiple Studies 5 Simultaneous Ordering of Multiple Studies 5 Repeated Imaging 5 Pre-Test Requirements 6 History 6 Imaging of the Brain 7 General Information/Overview 7 Scope 7 Technology Considerations 7 Definitions 8 Clinical Indications 9 Congenital and Developmental Conditions 9 Ataxia, congenital or hereditary 9 Developmental delay (Pediatric only) 9 Congenital cerebral anomalies 10 Infection 10 Infection 10 Inflammatory Conditions 11 Multiple (...) , covering the entire calvarium and intracranial contents. Coverage may vary depending on the specific clinical indication. Disadvantages of CT include exposure to ionizing radiation and risks associated with infusion of iodinated contrast media, including allergic reactions or renal compromise. Magnetic resonance imaging (MRI) is preferable to CT in most clinical scenarios. It is the study of choice for visualization of brain parenchyma and white matter tracts. It is also preferred for imaging

2019 AIM Specialty Health

20. Cerebral Ventricle

Cerebral Ventricle Cerebral Ventricle Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Cerebral Ventricle Cerebral Ventricle Aka (...) browser window. Related Studies (from Trip Database) Ontology: Cerebral aqueduct (C0007769) Definition (NCI) A channel that connects the third and fourth ventricles of the brain. Definition (MSH) Narrow channel in the MESENCEPHALON that connects the third and fourth CEREBRAL VENTRICLES. Concepts Body Space or Junction ( T030 ) MSH SnomedCT 279249003 , 80447000 English Aqueduct of Sylvius , Aqueduct, Cerebral , Aqueducts, Cerebral , Cerebral Aqueduct , Cerebral Aqueducts , Sylvius Aqueduct , Cerebral

2018 FP Notebook

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