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Cerebral Sinus

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1. Cerebral Venous Sinus Thrombosis Standards

Cerebral Venous Sinus Thrombosis Standards Current Endovascular Strategies for Cerebral Venous Sinus Thrombosis 1. A combination of MRI/MRV or CT/CTV studies should be performed in patients with suspected CVT (Class I; Level of Evidence C). 2. DSA as a diagnostic modality is indicated in cases of suspected CVT when diagnosis of CVT cannot be reliably established with non-invasive imaging alone (Class IIa; Level of Evidence C). 3. Anticoagulation with unfractionated heparin or low molecular (...) the optimal restoration of venous outflow in CVT. In many cases, a variety of treatment approaches is required to establish sinus patency. REFERENCE LINK: Lee SK et al. “Current endovascular strategies for cerebral venous thrombosis: report of the SNIS Standards and Guidelines Committee,” J Neurointerv Surg. 2018; 10:803-810. Last Updated by Justin F. Fraser, MD 7-23-2018

2018 Society of NeuroInterventional Surgery

2. Papilledema revisiting after sinus angioplasty of chronic cerebral venous sinus thrombosis (PubMed)

Papilledema revisiting after sinus angioplasty of chronic cerebral venous sinus thrombosis This case series aimed to review the significance of revisiting papilledema after successful cerebral venous sinus thrombosis (CVST) management with sinus angioplasty. Four patients presented with blurring and transient obscuration of vision with papilledema, headache, tinnitus, and vomiting. On magnetic resonance venography and digital subtraction angiography, chronic transverse sinus thrombosis

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2018 Indian journal of ophthalmology

3. Clinical features of seizures after cerebral venous sinus thrombosis and its effect on outcome among Chinese Han population (PubMed)

Clinical features of seizures after cerebral venous sinus thrombosis and its effect on outcome among Chinese Han population Clinical features of epileptic seizures after cerebral venous sinus thrombosis (CVST) among Chinese patients are not known, and it is still controversial whether seizures would affect the outcome of CVST.In a Chinese hospital-based study of consecutive patients with CVST between 2003 and 2015, we described the clinical features of seizures and determined the predictors (...) haemorrhage (OR 3.93, 95% CI 1.16 to 13.26, p=0.027), cerebral infarction (OR 3.78, 95% CI 1.15 to 12.36, p=0.029) and superior sagittal sinus thrombosis (OR 3.38, 95% CI 91.16 to 9.86, p=0.026) were independent predictors for seizures. The overall in-hospital case-fatality rate was 2.0% (3/151), and 21 (13.9%) had mRS >2 at discharge. Compared with patients without seizures, patients with seizures were more likely to have a worse outcome (p=0.02) at discharge, independent of age, gender, clinical

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2017 Stroke and vascular neurology

4. Combined use of stent-retriever and aspiration thrombectomy for cerebral venous sinus thrombosis involving the straight sinus: A case report (PubMed)

Combined use of stent-retriever and aspiration thrombectomy for cerebral venous sinus thrombosis involving the straight sinus: A case report Cerebral venous sinus thrombosis (CVST) is generally treated with anticoagulation therapy, however, endovascular therapy is considered for refractory cases. A 42-year-old woman presented with a progressive disturbance in consciousness, and diagnosed CVST in the straight sinus (SS). Recanalization of SS was achieved by emergent thrombectomy using aspiration

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2017 Interventional Neuroradiology

5. Batroxobin in combination with anticoagulation may promote venous sinus recanalization in cerebral venous thrombosis: A real-world experience. (PubMed)

Batroxobin in combination with anticoagulation may promote venous sinus recanalization in cerebral venous thrombosis: A real-world experience. The objective of this study was to evaluate cerebral venous recanalization with magnetic resonance black-blood thrombus imaging (MRBTI) in patients with cerebral venous thrombosis (CVT) who underwent batroxobin treatment in combination with anticoagulation.A total of 31 CVT patients were enrolled in this real-world registry study. The patients were (...) ratio of patients with the attenuation of stenosis [adjusted OR (95%CI) of 26.4 (1.10-635)]; as well as a higher ratio of segments with stenosis reversion [adjusted OR (95%CI) of 4.52 (1.48-13.8)]. However, neurological deficits between the two groups showed no statistical difference at 90-day follow-up (P > 0.05).Batroxobin may promote venous sinus recanalization and attenuate CVT-induced stenosis. Further randomized study of this promising drug may be warranted to better delineate the amount

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2019 CNS neuroscience & therapeutics

6. Safety and efficacy of intravascular ultrasound as an adjunct to stenting for cerebral venous sinus stenosis-induced idiopathic intracranial hypertension: a pilot study. (PubMed)

Safety and efficacy of intravascular ultrasound as an adjunct to stenting for cerebral venous sinus stenosis-induced idiopathic intracranial hypertension: a pilot study. OBJECTIVESymptomatic intracranial hypertension can be caused by cerebral venous sinus stenosis (CVSS) and cerebral venous sinus thrombotic (CVST) stenosis, which is usually found in some patients with idiopathic intracranial hypertension (IIH). Recently, at the authors' center, they utilized intravascular ultrasound (IVUS (...) ) as an adjunct to conventional venoplasty or stenting to facilitate diagnosis and accurate stent placement in CVSS.METHODSThe authors designed a retrospective review of their prospective database of patients who underwent IVUS-guided venous sinus stenting between April 2016 and February 2017. Clinical, radiological, and ophthalmological information was recorded and analyzed. IVUS was performed in 12 patients with IIH (9 with nonthrombotic CVSS, 3 with secondary stenosis combined with CVST) during venoplasty

2019 Journal of Neurosurgery

7. Cerebral venous sinus thrombosis due to hyperhomocysteinemia with cystathionine-β-synthase (CBS) gene mutation: A case report. (PubMed)

Cerebral venous sinus thrombosis due to hyperhomocysteinemia with cystathionine-β-synthase (CBS) gene mutation: A case report. Risk factors of cerebral venous sinus thrombosis (CVST) are usually divided into acquired risks (e.g., trauma and pregnancy) and genetic risks (inherited thrombophilia). It is essential but not easy to identify the exact one for each patient.A 14-year-old male patient was admitted in our hospital because of progressively exacerbated severe headache and vomiting for 3

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2019 Medicine

8. A clinical research on the potential pathogenesis of somatic cancer related cerebral venous sinus thrombosis. (PubMed)

A clinical research on the potential pathogenesis of somatic cancer related cerebral venous sinus thrombosis. To investigate the pathogenesis of somatic solid cancer-related cerebral venous sinus thrombosis (CVST).A total of 174 patients with CVST were recruited from the hospital between January 2006 and December 2017 and divided into two groups: (1) somatic cancer-related CVST group, defined as active somatic solid cancer patients with acute CVST; (2) cancer group (CG), defined as active

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2019 Medicine

9. A case report of oral contraceptive misuse induced cerebral venous sinus thrombosis and dural arteriovenous fistula. (PubMed)

A case report of oral contraceptive misuse induced cerebral venous sinus thrombosis and dural arteriovenous fistula. Consumption of oral contraceptive pills (OCP) is a known risk factor for cerebral venous sinus thrombosis (CVST) among women. Development of dural arteriovenous fistula (dAVF) afterwards was very uncommon. We present a rare chronic complication of development of dAVF after CVST.A 22-year-old woman suffered headache for a week. She was then admitted into our hospital.Contrast (...) enhanced magnetic resonance venography (MRV) demonstrated the thrombosis of the left transverse-sigmoid sinus the second day.The intravenous thrombolysis was carried out. As the symptoms improved, the patient was discharged, while the treatment with oral dabigatran continued. However, 3 months after the onset, magnetic resonance imaging (MRI) showed swelling brainstem, and digital subtraction angiography (DSA) confirmed a dAVF. Clipping of the fistula was conducted, and her clinical symptoms improved

2019 Medicine

10. Cerebral venous sinus thrombosis in a young patient with ulcerative colitis: A case report. (PubMed)

Cerebral venous sinus thrombosis in a young patient with ulcerative colitis: A case report. Cerebral venous sinus thrombosis (CVST) represents one of the most alarming forms of hemostatic abnormalities that may occur in patients with inflammatory bowel diseases (IBDs).Here we report a case of a 25-year-old male with ulcerative colitis, who developed such thromboembolic complication during flare of the disease. CVST in our patient was clinically manifested by headache and nausea.Angio-magnetic (...) resonance imaging scan of the head revealed segments of contrast filling defects/absence indicating right dural venous sinus thrombosis of the transverse sinus.Immediate treatment with low-molecular-weight heparin has been introduced and led to full remission of symptoms and total recanalization of the thrombotic cerebral regions.Currently (over 2 years after diagnosis) the patient is in remission of the disease, and no further thromboembolic complications have been observed.Our case study highlights

2019 Medicine

11. Safety of Pregnancy After Cerebral Venous Thrombosis: Results of the ISCVT (International Study on Cerebral Vein and Dural Sinus Thrombosis)-2 PREGNANCY Study. (PubMed)

Safety of Pregnancy After Cerebral Venous Thrombosis: Results of the ISCVT (International Study on Cerebral Vein and Dural Sinus Thrombosis)-2 PREGNANCY Study. Pregnancy is associated with increased risk of venous thrombotic events, including cerebral venous thrombosis. We aimed to study the complications and outcome of subsequent pregnancies in women with previous cerebral venous thrombosis.Follow-up study of women with acute cerebral venous thrombosis at childbearing age included (...) in a previously described cohort (International Study of Cerebral Vein and Dural Sinus Thrombosis). Patients were interviewed by local neurologists to assess rate of venous thrombotic events, pregnancy outcomes, and antithrombotic prophylaxis during subsequent pregnancies.A total of 119 women were included, with a median follow-up of 14 years. Eighty-two new pregnancies occurred in 47 women. In 83% (68 of 82), some form of antithrombotic prophylaxis was given during at least 1 trimester of pregnancy

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2017 Stroke

12. Cerebral venous sinus thrombosis. (PubMed)

Cerebral venous sinus thrombosis. The cerebral venous system is an unusual site of thrombosis, with a particularly high incidence in young adults. This incidence has increased in past decades because of the improvement of neuroradiological techniques. Risk factors for cerebral venous sinus thrombosis overlap with those of other venous thromboembolism sites; however, some are specific for this particular anatomical district. Prognosis is favorable in most cases if diagnosis is made rapidly (...) trials are lacking. Specifically, this review addresses the epidemiology, clinical presentation and course, risk factors, and treatment of cerebral venous sinus thrombosis, with a special focus on the pediatric population.© 2018 International Society on Thrombosis and Haemostasis.

2018 Journal of Thrombosis and Haemostasis

13. Nonaneurysmal Perimesencephalic Subarachnoid Hemorrhage as an Atypical Initial Presentation of Cerebral Venous Sinus Thrombosis: A Case Report (PubMed)

Nonaneurysmal Perimesencephalic Subarachnoid Hemorrhage as an Atypical Initial Presentation of Cerebral Venous Sinus Thrombosis: A Case Report BACKGROUND Subarachnoid hemorrhage is rarely the first presentation of cerebral venous sinus thrombosis. This case study emphasizes the presentation of perimesencephalic subarachnoid hemorrhage due to cerebral venous sinus thrombosis and the importance of neurovascular imaging for reliable diagnosis of nonaneurysmal perimesencephalic subarachnoid (...) hemorrhage due to cerebral venous sinus thrombosis. CASE REPORT We describe a case of cerebral venous sinus thrombosis manifesting initially as subarachnoid hemorrhage. Non-contrast computed tomography showed evidence of subarachnoid hemorrhage involving the prepontine and suprasellar cisterns. Cerebral convexities were totally spared while parenchymal microbleeding was observed in the midbrain. The diagnosis was confirmed by magnetic resonance arteriography and venography. Treatment included low

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2018 The American journal of case reports

14. Cerebral Venous Sinus Thrombosis in a Patient with Meningococcal Meningitis (PubMed)

Cerebral Venous Sinus Thrombosis in a Patient with Meningococcal Meningitis Meningococcal meningitis has a wide range of neurological complications. However, cerebral venous sinus thrombosis (CVST) following infection with Neisseria meningitidis is uncommon. We report a case of CVST in a 42-year-old male admitted with meningococcal meningitis. The patient was managed with antibiotics. Due to altered coagulation parameters observed in fulminant cases of meningococcemia, deployment

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2018 Oman medical journal

15. Cerebral Venous Sinus Thrombosis in a Patient with Ulcerative Colitis Flare (PubMed)

Cerebral Venous Sinus Thrombosis in a Patient with Ulcerative Colitis Flare Inflammatory bowel disease is characterized by a chronic inflammatory state and is therefore associated with abnormalities in coagulation and a hypercoagulable state. Cerebral venous sinus thrombosis is a rare complication of inflammatory bowel disease yet contributes significant morbidity and mortality to those affected. Early diagnosis is critical, as a delay in diagnosis portends a worse prognosis. This paper seeks (...) to highlight the increased risk of venous sinus thrombosis in patients with inflammatory bowel disease. We start by discussing the case of a seventeen-year-old female who presented with ulcerative colitis flare and developed new-onset seizures, found to be caused by a large venous sinus thrombosis.

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2018 Case reports in neurological medicine

16. Seizure in cerebral venous and sinus thrombosis (PubMed)

Seizure in cerebral venous and sinus thrombosis Many conflicting issues exist about seizure in the setting of cerebral venous and sinus thrombosis (CVST). In this article we aimed to address the existing data regarding incidence, characteristics, predictors, treatment, and prognosis of acute and late seizures in patients with CVST and to prepare more practical information for clinicians. PubMed, Embase, Web of science and Cochrane databases were searched within 1966-2016 using relevant keywords (...) . A total of 63 papers met the inclusion criteria. Seizures are classified as acute symptomatic seizures (ASS; first 14 days) and post-CVST epilepsy (PCE; after 14 days). The incidence had been reported in a wide range of 6.9-76% for ASS and 4-16% for PCE. Focal and generalized seizures were observed with different predominance. ASS commonly occurred in patients with loss of consciousness, focal neurological deficits, supratentorial lesions and thrombosis in superior sagittal sinus, straight sinus

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2018 Epilepsia Open

17. Endovascular treatment for hemorrhagic cerebral venous sinus thrombosis: experience with 9 cases for 3 years (PubMed)

Endovascular treatment for hemorrhagic cerebral venous sinus thrombosis: experience with 9 cases for 3 years We experienced a series of patients with hemorrhagic CVST, who were successfully treated with endovascular treatment (EVT). The aim was to explore the best scheme for the future through our treatment data of hemorrhagic CVST.A retrospective analysis was conducted, selecting nine hemorrhagic CVST patients, who were mainly treated with EVT. Characteristics of hemorrhagic CVST were recorded (...) hemorrhagic cerebral venous sinus thrombosis.

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2018 American journal of translational research

18. Letter in Reply: Thrombophilic Evaluation in Cases of Cerebral Venous Sinus Thrombosis (PubMed)

Letter in Reply: Thrombophilic Evaluation in Cases of Cerebral Venous Sinus Thrombosis 30410701 2018 11 14 1999-768X 33 6 2018 Nov Oman medical journal Oman Med J Letter in Reply: Thrombophilic Evaluation in Cases of Cerebral Venous Sinus Thrombosis. 538 10.5001/omj.2018.100 Chirakkara Sudhir Kumar Palat SKP Department of Neurology, Mafraq Hospital, Abu Dhabi, UAE. eng Editorial Oman Oman Med J 101526350 1999-768X 2018 11 10 6 0 2018 11 10 6 0 2018 11 10 6 1 ppublish 30410701 10.5001/omj

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2018 Oman medical journal

19. Thrombophilic Evaluation in Cases of Cerebral Venous Sinus Thrombosis (PubMed)

Thrombophilic Evaluation in Cases of Cerebral Venous Sinus Thrombosis 30410700 2018 11 14 1999-768X 33 6 2018 Nov Oman medical journal Oman Med J Thrombophilic Evaluation in Cases of Cerebral Venous Sinus Thrombosis. 537 10.5001/omj.2018.99 Hemasian Helia H Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran. Hakamifard Atousa A Department of Infectious Diseases, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. eng Editorial Oman Oman Med J

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2018 Oman medical journal

20. Cerebral venous sinus thrombosis in a young female misdiagnosed as migraine ending in a permanent vegetative state: a case report and review of the literature (PubMed)

Cerebral venous sinus thrombosis in a young female misdiagnosed as migraine ending in a permanent vegetative state: a case report and review of the literature Cerebral venous thrombosis refers to acute thrombosis or blood clots that can lead to strokes. This illness can be misdiagnosed as a migraine, resulting in a delay in management and catastrophic outcomes. We present a pitfall case that highlights the importance of careful history taking and physician awareness in diagnosing cerebral (...) tomography of the head that was interpreted by an emergency consultant, who revealed the diagnosis despite limited resources. Unfortunately, the patient developed complications of the hydrocephalus, transtentorial brain herniation, and intraventricular hemorrhage that required multiple neurosurgical interventions and resulted in a permanent vegetative state.Cerebral venous sinus thrombosis is an uncommon and tricky condition with unpredictable presentation and prognosis. A physician needs to have a high

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2018 Journal of medical case reports

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