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1. Cellulitis and erysipelas: antimicrobial prescribing

Cellulitis and erysipelas: antimicrobial prescribing Cellulitis and erysipelas: antimicrobial Cellulitis and erysipelas: antimicrobial prescribing prescribing NICE guideline Published: 27 September 2019 www.nice.org.uk/guidance/ng141 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful (...) in a way that would be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Cellulitis and erysipelas: antimicrobial prescribing (NG141) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 36Contents

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

5. Cellulitis

Cellulitis Cellulitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Cellulitis Last reviewed: February 2019 Last updated: June 2018 Summary Diagnosis can usually be made on history and examination only, although purulent focus culture and molecular diagnostic procedures should be performed if cellulitis is associated with a wound or pustular focus. Prior episodes of cellulitis, pre-existing lymphoedema or venous (...) insufficiency, and tinea pedis can all predispose to this condition. Antibiotics targeted at the most common aetiologies (streptococci and Staphylococcus aureus ) usually result in resolution. Definition Cellulitis is an acute spreading infection of the skin with visually indistinct borders that principally involves the dermis and subcutaneous tissue. It is characterised by erythema, oedema, warmth, and tenderness, and commonly occurs in an extremity. Erysipelas is a distinct form of superficial cellulitis

2018 BMJ Best Practice

6. Peri-orbital and orbital cellulitis

Peri-orbital and orbital cellulitis Peri-orbital and orbital cellulitis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Peri-orbital and orbital cellulitis Last reviewed: February 2019 Last updated: March 2018 Summary Peri-orbital cellulitis is an infectious process occurring in the eyelid tissues superficial to (anterior to or above) the orbital septum. It is usually due to superficial tissue injury (e.g., insect (...) bite or chalazion). Orbital cellulitis is an infectious process affecting the muscles and fat within the orbit, posterior or deep to the orbital septum, not involving the globe. It is usually due to underlying bacterial sinusitis. Peri-orbital cellulitis is of concern in children because it may be secondary to occult underlying bacterial sinusitis or, rarely, due to bacteraemic spread from a primary infection (e.g., pneumonia), and may rapidly progress to orbital cellulitis in children

2018 BMJ Best Practice

7. Interventions for the prevention of recurrent erysipelas and cellulitis. (PubMed)

Interventions for the prevention of recurrent erysipelas and cellulitis. Erysipelas and cellulitis (hereafter referred to as 'cellulitis') are common bacterial skin infections usually affecting the lower extremities. Despite their burden of morbidity, the evidence for different prevention strategies is unclear.To assess the beneficial and adverse effects of antibiotic prophylaxis or other prophylactic interventions for the prevention of recurrent episodes of cellulitis in adults aged over 16.We (...) for the prevention of recurrent cellulitis.Two authors independently carried out study selection, data extraction, assessment of risks of bias, and analyses. Our primary prespecified outcome was recurrence of cellulitis when on treatment and after treatment. Our secondary outcomes included incidence rate, time to next episode, hospitalisation, quality of life, development of resistance to antibiotics, adverse reactions and mortality.We included six trials, with a total of 573 evaluable participants, who were

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2017 Cochrane

8. Controversies in the Diagnosis and Management of Cellulitis

Controversies in the Diagnosis and Management of Cellulitis Emergency Medicine > Journal Club > Archive > July 2017 Toggle navigation July 2017 Controversies in the Diagnosis and Management of Cellulitis Vignette You're moonlighting in the local ED one afternoon, when you encounter Mrs. X, a 40-year-old woman with rheumatoid arthritis, for which she takes Methotrexate. She was gardening three days prior to presentation when she suffered a small cut to her left ankle from a misplaced spade (...) in both legs for quite some time, chalked up in the past to chronic lymphedema and CHF, but now has redness and pain to both ankles and lower legs. Given the severity of the redness and swelling, you elect to treat the patient for cellulitis and order vancomycin, then place an admission order. The hospitalist muses that perhaps the patient has , but admits that it's probably wort treating for potential cellulits. Thinking back to both patients later in the day, you begin to worry about your treatment

2017 Washington University Emergency Medicine Journal Club

9. Pre-septal cellulitis

Pre-septal cellulitis Cellulitis, preseptal and orbital submit The College submit You're here: Cellulitis, preseptal and orbital Cellulitis, preseptal and orbital The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Aetiology Infections of the periorbital and orbital tissues range in severity, from relatively minor to potentially life-threatening (...) . These infections occur most commonly in children under the age of 10 years Preseptal cellulitis bacterial infection of tissues lying anterior to the orbital septum (therefore not an orbital condition) in young children, high risk of extension into the orbit Orbital cellulitis bacterial infection of tissues lying posterior to the orbital septum (within the orbit) severe sight and life-threatening emergency For both conditions, the usual causative organisms are Staphylococcus, Streptococcus and Haemophilus

2018 College of Optometrists

10. Long-term antibiotics likely to reduce risk of recurrent cellulitis

Long-term antibiotics likely to reduce risk of recurrent cellulitis Long-term antibiotics likely to reduce risk of recurrent cellulitis Discover Portal Discover Portal Long-term antibiotics likely to reduce risk of recurrent cellulitis Published on 17 October 2017 doi: Antibiotics may reduce the risk of leg cellulitis by about two thirds, in adults who have had at least two previous episodes, but only while they take the antibiotics. There is limited evidence measuring the efficacy of other (...) forms of prevention. A review of five studies showed that the risk of developing repeated cellulitis was reduced in participants who were taking long-term (more than six months) penicillin or erythromycin, compared with a control group. Once the antibiotic course had finished, participants’ risk of recurrent cellulitis was no different from the control group. Cellulitis is a bacterial skin infection that spreads and worsens quickly. Risk of recurrence is high in people with a predisposing condition

2019 NIHR Dissemination Centre

11. Cephalexin plus trimethoprim-sulfamethoxazole was not superior to cephalexin alone for the treatment of outpatient non-purulent cellulitis

Cephalexin plus trimethoprim-sulfamethoxazole was not superior to cephalexin alone for the treatment of outpatient non-purulent cellulitis Cephalexin plus trimethoprim-sulfamethoxazole was not superior to cephalexin alone for the treatment of outpatient non-purulent cellulitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use (...) of outpatient non-purulent cellulitis Article Text Commentary: General medicine Cephalexin plus trimethoprim-sulfamethoxazole was not superior to cephalexin alone for the treatment of outpatient non-purulent cellulitis Loren G Miller Statistics from Altmetric.com Commentary on: Moran GJ, Krishnadasan A, Mower WR, et al . Effect of cephalexin plus trimethoprim-sulfamethoxazole vs cephalexin alone on clinical cure of uncomplicated cellulitis: a randomised clinical trial. JAMA 2017;317:2088–96. Context Skin

2017 Evidence-Based Medicine (Requires free registration)

12. Do Patients with Cellulitis Need to be Hospitalized? A Systematic Review and Meta-analysis of Mortality Rates of Inpatients with Cellulitis. (PubMed)

Do Patients with Cellulitis Need to be Hospitalized? A Systematic Review and Meta-analysis of Mortality Rates of Inpatients with Cellulitis. Cellulitis is a common cause of hospitalization. In the USA, the International Classification of Diseases (ICD) code "other cellulitis and abscess" accounts for 1.4% of all admissions and $5.5 billion in annual costs. The Infectious Disease Society of America recommends hospitalization for patients with cellulitis under certain circumstances (...) but there is little actual clinical evidence to guide the decision to admit. The purpose of this study is to determine the mortality rate of patients hospitalized with cellulitis and to ascertain if the rate is comparable to the rate for low risk patients with community acquired pneumonia that are currently recommended for outpatient management.A systematic literature search was conducted for studies of consecutive patients hospitalized with cellulitis or erysipelas that reported inpatient mortality. Study

2018 Journal of General Internal Medicine

13. Which outcomes are reported in cellulitis trials? Results of a review of outcomes included in cellulitis trials and a patient priority setting survey. (PubMed)

Which outcomes are reported in cellulitis trials? Results of a review of outcomes included in cellulitis trials and a patient priority setting survey. There is an emerging need to develop consistent outcomes in clinical trials to allow effective comparison of treatment effects. No systematic review has previously looked at the reporting of outcome measures used in randomized controlled trials (RCTs) on the treatment and prevention of cellulitis (erysipelas).The primary aim of this review (...) was to describe the breadth of outcomes reported from RCTs on cellulitis treatment and prevention. The secondary aim was to identify outcome themes from patients' and healthcare professionals' feedback from a cellulitis Priority Setting Partnership (PSP).We conducted a review of all outcome measures used in RCTs from two recent Cochrane reviews. Free-text responses from a cellulitis priority setting survey were used to understand the perspectives of patients and healthcare professionals.Outcomes from 42 RCTs

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2017 British Journal of Dermatology

14. Adjunctive clindamycin for cellulitis: a clinical trial comparing flucloxacillin with or without clindamycin for the treatment of limb cellulitis. (PubMed)

Adjunctive clindamycin for cellulitis: a clinical trial comparing flucloxacillin with or without clindamycin for the treatment of limb cellulitis. To compare flucloxacillin with clindamycin to flucloxacillin alone for the treatment of limb cellulitis.Parallel, double-blinded, randomised controlled trial.Emergency department attendances and general practice referrals within 20 hospitals in England.Flucloxacillin, at a minimum of 500 mg 4 times per day for 5 days, with clindamycin 300 mg 4 times (...) . There was no clinically significant difference in any secondary outcome measures. There was no significant difference in the number of patients stating that they had returned to normal activities at the day 30 interview in the flucloxacillin with clindamycin allocation (99/121, 82%) versus flucloxacillin alone (104/129, 81%)-adjusted OR 0.90 (95% CI 0.44 to 1.84).The addition of a short course of clindamycin to flucloxacillin early on in limb cellulitis does not improve outcome. The addition of clindamycin doubles

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2017 BMJ open

15. Long-term antibiotics likely to reduce risk of recurrent cellulitis

Long-term antibiotics likely to reduce risk of recurrent cellulitis Long-term antibiotics likely to reduce risk of recurrent cellulitis Discover Portal Discover Portal Long-term antibiotics likely to reduce risk of recurrent cellulitis Published on 17 October 2017 doi: Antibiotics may reduce the risk of leg cellulitis by about two thirds, in adults who have had at least two previous episodes, but only while they take the antibiotics. There is limited evidence measuring the efficacy of other (...) forms of prevention. A review of five studies showed that the risk of developing repeated cellulitis was reduced in participants who were taking long-term (more than six months) penicillin or erythromycin, compared with a control group. Once the antibiotic course had finished, participants’ risk of recurrent cellulitis was no different from the control group. Cellulitis is a bacterial skin infection that spreads and worsens quickly. Risk of recurrence is high in people with a predisposing condition

2018 NIHR Dissemination Centre

16. Orbital apex syndrome from bacterial sinusitis without orbital cellulitis (PubMed)

Orbital apex syndrome from bacterial sinusitis without orbital cellulitis To describe a case of orbital apex syndrome as a result of isolated bacterial sinusitis.A 63-year-old woman presented with an orbital apex syndrome from isolated bacterial sinusitis with rapidly declining visual acuity to no light perception. We compared our case with 6 similar cases of severe vision loss from isolated bacterial sinusitis. In contrast to previously published cases, our patient presented with good vision

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2018 American journal of ophthalmology case reports

17. Cellulitis and Soft Tissue Infections. (PubMed)

Cellulitis and Soft Tissue Infections. Cellulitis and soft tissue infections are a diverse group of diseases that range from uncomplicated cellulitis to necrotizing fasciitis. Management of predisposing conditions is the primary means of prevention. Cellulitis is a clinical diagnosis and thus is made on the basis of history and physical examination. Imaging may be helpful for characterizing purulent soft tissue infections and associated osteomyelitis. Treatment varies according to the type

2018 Annals of Internal Medicine

18. Varicella zoster causing preseptal cellulitis - uncommon but possible (PubMed)

Varicella zoster causing preseptal cellulitis - uncommon but possible Varicella has been known to be a harmless childhood disease. However, it has been reported that severe complications have taken place following Varicella infection, in both immunocompetent, as well as immunocompromised, individuals. Cutaneous complications of Varicella may manifest as preseptal cellulitis, albeit rarely.We present a case of a 4-year-old boy who presented with symptoms and signs of preseptal cellulitis (...) following Varicella infection. He was referred to the otorhinolaryngology team for a nasoendoscopy to rule out sinusitis, in view of the fear that a child presenting with a swollen red eye may be a case of true orbital cellulitis. He was treated successfully with intravenous antibiotics and surgical drainage of the preseptal collection.It is imperative for clinicians to be aware that a simple Varicella infection may lead to cutaneous complications in the pediatric age group, especially in children who

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2017 Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia

19. Case report of the family transmission of Streptococcus pyogenes orbital cellulitis (PubMed)

Case report of the family transmission of Streptococcus pyogenes orbital cellulitis This is a case report of an unusual case of the family transmission of Streptococcus pyogenes infection in three siblings. One brother contracted the infection which resulted in orbital cellulitis of two of his siblings, in the absence of anatomical or immunological predisposing factors.A young boy contracted an uncomplicated S pyogenes upper respiratory tract infection. The twin brother closely followed (...) by the older sister both developed a S pyogenes orbital cellulitis a couple of days later.To our knowledge, this is the first case ever reported of family transmission of orbital cellulitis. This highlights the importance of early diagnosis and treatment of S pyogenes, and the role of throat cultures as means of diagnosis even in the absence of symptoms or signs of pharyngitis.

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2017 American journal of ophthalmology case reports

20. Low-dose penicillin for recurrent cellulitis?

Low-dose penicillin for recurrent cellulitis? Low-dose penicillin for recurrent cellulitis? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Low-dose penicillin for recurrent cellulitis? View/ Open Date 2014-01 Format Metadata Abstract Practice changer: Prescribe low-dose penicillin to patients with recurrent leg (...) cellulitis to decrease the frequency of recurrent episodes. URI Part of Citation Journal of Family Practice, 63(1) 2014: E10-E12. Rights OpenAccess. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. Collections hosted by hosted by

2014 PURLS

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