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Caustic Ingestion

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1. Tide Pod Challenge: Managing caustic laundry pod ingestions

Tide Pod Challenge: Managing caustic laundry pod ingestions Tide Pod Challenge: Managing caustic laundry pod ingestions - CanadiEM Tide Pod Challenge: Managing caustic laundry pod ingestions In by Tanishq Suryavanshi January 31, 2018 A Case of Laundry Pod Ingestion You are called to the low-acuity side of your department for a two year old child who was triaged three hours ago. The child was witnessed to eat a laundry pod at home, but was stable on arrival so sent to the back. Now, the child (...) is wheezing, seems drowsy, and is tachycardic. When you approach the child, he begins to cry and you note the sound of a baby pterodactyl that you recognize as stridor. OVERVIEW Laundry pods are caustic substances that cause functional and histological damage due to direct contact with the body. Recently, these pods have gained a lot of media attention due to the “Tide Pod Challenge” in which people purposefully ingest the colorful, candy-appearing pods, and post videos online. These types of poisonings

2018 CandiEM

2. Clinical and endoscopic findings of children hospitalized in Qa’em Hospital of Mashhad due to caustic ingestion (2011–2013) (PubMed)

Clinical and endoscopic findings of children hospitalized in Qa’em Hospital of Mashhad due to caustic ingestion (2011–2013) One of the leading causes of damage to the gastrointestinal tract in children is caustic ingestion which is sometimes life-threatening. The most reliable way to study the severity and extent of damage is endoscopy, which can be harmless in terms of time and technique. The aim of this study was to investigate, evaluate and compare clinical findings and endoscopic (...) results of caustic ingestion.This retrospective cross-sectional study was conducted on the records of children diagnosed with caustic ingestion, and hospitalized in Qa'em Hospital of Mashhad from March 2011 to December 2013. Intended data were extracted from patients' records and in case of any ambiguity, it was removed by phone call. Obtained data were analyzed using SPSS 11.5 and chi-square test.Of 54 patients, there were 36 cases of burn with acidic substance and 16 cases of burn with alkaline

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2017 Electronic physician

3. PHARYNGO-ILEO-COLO-ANASTOMOSIS WITH MICRO-VASCULAR BLOOD SUPPLY AUGMENTATION FOR ESOPHAGO-GASTRIC REPLACEMENT DUE TO ESOPHAGO-GASTRIC NECROSIS AFTER CAUSTIC INGESTION (PubMed)

PHARYNGO-ILEO-COLO-ANASTOMOSIS WITH MICRO-VASCULAR BLOOD SUPPLY AUGMENTATION FOR ESOPHAGO-GASTRIC REPLACEMENT DUE TO ESOPHAGO-GASTRIC NECROSIS AFTER CAUSTIC INGESTION Complete esophago-gastric necrosis after caustic ingestion is a challenging surgical scenario for reconstruction of the upper digestive transit.To present a surgical technique for reconstruction of the upper digestive tract after total esophagectomy and gastrectomy due to esophageal and gastric necrosis.The transit was re (...) -established by means of a pharyngo-ileo-colic interposition with microsurgical arterial and venous anastomosis for augmentation of blood supply. Colo-duodeno-anastomosis and ileo-transverse colic anastomosis were performed for complete digestive transit reconstruction.This procedure was applied in a case of 41 years male attempted suicide by ingesting alkali caustic liquid (concentrated sodium hydroxide). Total necrosis of the esophagus and stomach occurred, which required initially total esophago

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2018 Arquivos Brasileiros de Cirurgia Digestiva : ABCD

4. Caustic ingestion. (PubMed)

Caustic ingestion. Corrosive ingestion is a rare but potentially devastating event and, despite the availability of effective preventive public health strategies, injuries continue to occur. Most clinicians have limited personal experience and rely on guidelines; however, uncertainty persists about best clinical practice. Ingestions range from mild cases with no injury to severe cases with full thickness necrosis of the oesophagus and stomach. CT scan is superior to traditional endoscopy (...) for stratification of patients to emergency resection or observation. Oesophageal stricture is a common consequence of ingestion and newer stents show some promise; however, the place of endoscopic stenting for corrosive strictures is yet to be defined. We summarise the evidence to provide a plan for managing these potentially life-threatening injuries and discuss the areas where further research is required to improve outcomes.Copyright © 2017 Elsevier Ltd. All rights reserved.

2016 Lancet

5. Caustic Ingestion in Children in South of Iran: A Two-Year Single Center Study (PubMed)

Caustic Ingestion in Children in South of Iran: A Two-Year Single Center Study BACKGROUND Caustic ingestion is one of the most important injuries during childhood, which leads to serious sequel. In this study, we evaluated the clinical manifestations, endoscopic appearance, complications, and treatment results in patients with caustic ingestion in our hospital. METHODS Hospital chart of patients with caustic ingestion who admitted to Nemazee Teaching Hospital affiliated to Shiraz University (...) of Medical Sciences during a 2-year period (2015-2016) were reviewed retrospectively. The age, sex, nature of the caustic agent, clinical presentations, grade of injury in endoscopy, degree of parents' education, site of ingestion, accidental or intentional attempts, complications, and outcomes were reviewed. RESULTS In this study the charts of 41 patients (26 boys and 15 girls) with caustic ingestion over the 2-year period were reviewed. The mean age of the patients was 4.4 year. Of them, 95.1% had

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2018 Middle East journal of digestive diseases

6. Novel Use of Ophthalmic pH Paper to Diagnose Malicious Caustic Ingestion in a Pediatric Patient (PubMed)

Novel Use of Ophthalmic pH Paper to Diagnose Malicious Caustic Ingestion in a Pediatric Patient Occult caustic ingestion in the pediatric population is a challenging diagnosis to make in the emergency department. Failure to suspect and diagnose a caustic ingestion can lead to potentially life-changing comorbidities. Historically, the diagnosis of caustic ingestion has been clinical without any suitable diagnostic tools to aid in the suspicion of occult cases. In this case, we describe a novel (...) use of ophthalmic pH paper to diagnose caustic ingestion in a three-year-old.

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2018 Clinical Practice and Cases in Emergency Medicine

7. Esophago-pericardial Fistula and Pneumopericardium from Caustic ingestion and Esophageal Stent. (PubMed)

Esophago-pericardial Fistula and Pneumopericardium from Caustic ingestion and Esophageal Stent. Esophagopericardial fistulas are rare. Most reported cases are related to malignancy or prior surgical intervention. We report a case of an esophagopericardial fistula presenting as pneumopericardium and purulent pericarditis in a patient with a history of caustic ingestion and an esophageal stent.Copyright © 2019 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

2018 Annals of Thoracic Surgery

8. Recurrent esophageal stricture from previous caustic ingestion treated with 40-year self-dilation: case report and review of literature. (PubMed)

Recurrent esophageal stricture from previous caustic ingestion treated with 40-year self-dilation: case report and review of literature. Corrosive esophageal strictures are common. The severity of the strictures depends on type, quantity, duration of contact and concentration of the caustic substance ingested. Endoscopic balloon dilation and endoscopic bougienage are a cornerstone in the management of the benign esophageal strictures and are the most widely used treatments, but are expensive

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2018 BMC Gastroenterology

9. Corticosteroid Treatment in the Acute Phase of Caustic Ingestion Management

Corticosteroid Treatment in the Acute Phase of Caustic Ingestion Management Corticosteroid Treatment in the Acute Phase of Caustic Ingestion Management - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Corticosteroid Treatment in the Acute Phase of Caustic Ingestion Management (CORTICAU) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03760354 Recruitment Status : Not yet recruiting First Posted : November 30, 2018 Last Update

2018 Clinical Trials

10. Relook endoscopy predicts the development of esophageal and antropyloric stenosis better than immediate endoscopy in patients with caustic ingestion. (PubMed)

Relook endoscopy predicts the development of esophageal and antropyloric stenosis better than immediate endoscopy in patients with caustic ingestion. Background and aims Early ( < 24 hours) esophagogastroduodenoscopy (EGD) is used to prognosticate mucosal injury after caustic ingestion. We aimed to compare differences in endoscopic grading on EGDs performed on day 5 and day 1 and to assess the impact of relook endoscopy findings on the development of esophageal and/or antropyloric cicatrization (...) . Patients and methods Consecutive patients admitted within 24 hours of caustic ingestion between 2009 and 2014 underwent EGD and had their mucosal changes graded. Injuries of grade ≤ 2a were classified as mild and ≥ 2b were classified as severe. Patients were followed up for the development of cicatrization and managed per protocol. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratios (LRs) were calculated to compare day 1 and day 5 EGD

2017 Endoscopy

11. Role of RDW in Prediction of Burn after Caustic Substance Ingestion (PubMed)

Role of RDW in Prediction of Burn after Caustic Substance Ingestion A quantifiable, quick, inexpensive and reproducible predictor is needed to decide if caustic substance ingestion results in burn regardless of the symptoms. A multicenter cohort study was conducted to investigate the predictive value of red cell distribution width (RDW) in detecting the esophageal burns. The data of 174 patients were retrospectively analyzed. Eleven patients were excluded due to inability to define (...) the substance ingested. Complete blood count (CBC) was taken at admission, and an esophagogastroduodenoscopy was performed within the first 12-24 h in all patients, regardless of their symptoms. The age and gender of the patients, the types of substances ingested, the parameters in the CBC and the severity of the esophageal injury were correlated. Esophageal burns were diagnosed in 38 of 163 patients (23.3%). The risk of esophageal burn with RDW values below 12.20 was significantly lower. Multivariate

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2017 Children

12. Epidemiologic Features and Outcomes of Caustic Ingestions; a 10-Year Cross-Sectional Study (PubMed)

Epidemiologic Features and Outcomes of Caustic Ingestions; a 10-Year Cross-Sectional Study Caustic ingestions are among the most prevalent causes of toxic exposure. The present 10-year survey aimed to evaluate the epidemiologic features and outcomes of caustic ingestion cases presenting to emergency department.This is a retrospective cross-sectional study on patients who were admitted to a referral toxicology center during 2004 to 2014, following caustic ingestion. Baseline characteristics (...) , presenting chief complaint, severity of mucosal injury, complications, imaging and laboratory findings as well as outcomes (need for ICU admission, need for surgery, mortality) were recorded, reviewing patients' medical profile, and analyzed using SPSS 22.348 patients with mean age of 37.76 ± 17.62 years were studied (55.6% male). The mean amount of ingested caustic agent was 106.69 ± 100.24 mL (59.2 % intentional). Intentional ingestions (p < 0.0001), acidic substance (p = 0.054), and higher volume

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2017 Emergency

13. Diagnostic Accuracy of Computed Tomography Scan in Detection of Upper Gastrointestinal Tract Injuries Following Caustic Ingestion (PubMed)

Diagnostic Accuracy of Computed Tomography Scan in Detection of Upper Gastrointestinal Tract Injuries Following Caustic Ingestion Endoscopy is an invasive procedure and finding noninvasive alternative tools in detection of probable upper gastrointestinal (GI) tract injuries following caustic ingestion is an area of interest. The present study aimed to evaluate the screening performance characteristics of thoraco-abdominal computed tomography (CT) scan in this regard.This prospective cross (...) sectional study was conducted on patients presenting to emergency department following acute caustic ingestion. The findings of CT scan and endoscopy regarding the presence of upper GI tract damage were compared and screening performance characteristics of CT scan were calculated using MedCalc software.34 patients with the mean age of 35.38±13.72 years were studied (58.8% male). The agreement rate between CT scan and endoscopy regarding the grade of esophageal and gastric injuries was moderate (K= 0.38

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2017 Emergency

14. Caustic Ingestion in the Elderly: Influence of Age on Clinical Outcome (PubMed)

Caustic Ingestion in the Elderly: Influence of Age on Clinical Outcome Caustic poisonings are still associated with many fatalities. Studies focusing on the elderly are rare. The purpose of the present study was to compare the clinical outcomes of caustic ingestion injury in elderly and non-elderly adults with regard to gender, intent of exposure, substance ingested, severity of mucosal injury, complications, and mortality. Caustic substance exposures reported to the National Toxicological (...) Information Centre in Slovakia during 1998-2015 were reviewed retrospectively. The patients were divided into two groups: the non-elderly (<60 years) and elderly adults (≥60 years). The mortality rate in the elderly was significantly higher (elderly 23.0% vs. non-elderly 11.3%; p = 0.041). The risk of fatal outcome in the elderly was increased by acid ingestion (OR = 7.822; p = 0.002), particularly hydrochloric acid (OR = 5.714, p = 0.006). The incidence of respiratory complications was almost two times

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2017 Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

15. Accuracy of Endoscopy in Predicting the Depth of Mucosal Injury Following Caustic Ingestion; a Cross-Sectional Study (PubMed)

Accuracy of Endoscopy in Predicting the Depth of Mucosal Injury Following Caustic Ingestion; a Cross-Sectional Study Esophagogastroduodenoscopy (EGD) is currently considered as the primary method of determining the degree of mucosal injury following caustic ingestion. The present study aimed to evaluate the screening performance characteristics of EGD in predicting the depth of gastrointestinal mucosal injuries following caustic ingestion.Adult patients who were referred to emergency department (...) due to ingestion of corrosive materials, over a 7-year period, were enrolled to this diagnostic accuracy study. Sensitivity, specificity, positive and negative predictive values as well as negative and positive likelihood ratios of EGD in predicting the depth of mucosal injury was calculated using pathologic findings as the gold standard.54 cases with the mean age of 35 ± 11.2 years were enrolled (59.25% male). Primary endoscopic results defined 28 (51.85%) cases as second grade and 26 (48.14

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2017 Emergency

16. CRACKCast E153 – Caustics

undergo endoscopy and be considered for admission. Asymptomatic patients can undergo endoscopy in the emergency department or be discharged with close follow-up monitoring. Gastric emptying or GI decontamination is not indicated for the majority of caustic ingestions. Concentration and pH are the most important characteristics of a substance to predict esophageal and gastric injury. Button batteries lodged in the airway or esophagus require endoscopic retrieval. Rosen’s In Perspective Caustic (...) detergents and laundry detergents have a pH higher than 12, but because the titratable alkaline reserve is low, tissue equilibration occurs quickly, and there is less risk of injury after ingestion. [1] Compare acid and alkali caustic burns Factors that influence the extent of injury from a caustic exposure include: Type of agent, Concentration of solution Volume Viscosity Duration of contact pH, and Presence or absence of food in the stomach. The titratable acid/alkaline reserve of an alkali or acid

2018 CandiEM

17. Controversies in the management of caustic ingestion injury: an evidence based review. (PubMed)

Controversies in the management of caustic ingestion injury: an evidence based review. Caustic ingestion of acid or alkaline substances can cause damage to the upper respiratory and upper digestive tract. Initial presentation following caustic ingestion can include oropharyngeal pain, dysphagia and stridor. It is due to this clinical presentation that the resident otolaryngologist is consulted to review and examine these patients to assess for airway compromise and commence initial management (...) and care until airway concern has passed.This review aims to provide evidence-based guidance in the management of those presenting with acute ingestion injury so that informed initial medical therapy can be commenced and appropriate investigations are arranged to optimize patient outcome.A literature review searched PubMed citing variations on the areas of controversies with 'caustic ingestion', 'corrosive ingestion', 'acid ingestion' and 'alkali ingestion' - from 1956 to present with language

2016 Clinical Otolaryngology

18. Caustic Ingestion in Children: a Systematic Review and Meta-Analysis. (PubMed)

Caustic Ingestion in Children: a Systematic Review and Meta-Analysis. Introduction: Caustic ingestion that occurs accidently is one of the most common problems in children. Methods: This systematic review has been performed by searching the databases including Science Direct, ProQuest, Google Scholar, and PubMed. A strategic search was performed with keywords including caustic, corrosive, ingestion, and children, and was limited to articles in English and Persian. Data were analyzed using (...) Comprehensive Meta-Analysis2 and PASW Statistics 18. Results: We selected 64 articles regarding caustic ingestion with a total sample of 11,345 cases. The data analysis indicated a higher consumption in young boys (age range 2.78 (2.02) years (OR=0.53 with a 95% confidence interval of 0.49-0.57 (P=0.08)). The most common caustic substances were household cleaning agents, particularly bleaches and cleaners. Esophageal cancer and death were reported as well as digestive and respiratory complications. Invasive

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2016 Journal of caring sciences

19. The Damage Pattern to the Gastrointestinal Tract Depends on the Nature of the Ingested Caustic Agent. (PubMed)

The Damage Pattern to the Gastrointestinal Tract Depends on the Nature of the Ingested Caustic Agent. The mechanisms of damage to the gastrointestinal tract after caustic ingestion are conditioned by the nature of the ingested agent. Whether the nature of the ingested agent has a direct influence on patient outcomes is unknown.From January 2013 to April 2015, 144 patients underwent emergency management for caustic injuries at the Saint Louis Hospital in Paris. There were 51 men (51 (...)  %) and the median age was 44 years [39, 48]. The ingested agents were soda-based strong alkali in 85 patients (59 %), strong acids in 36 patients (25 %), and bleach in 23 patients (16 %). Emergency and long-term outcomes were compared according to the nature of the ingested agent.Four patients died (3 %) and 40 patients (28 %) experienced complications. After bleach ingestion, emergency morbidity and mortality were nil, no patient required esophageal reconstruction, and functional outcome was successful in all

2016 World Journal of Surgery

20. Swallowing dynamics status post caustic ingestion in a pediatric patient: A multidisciplinary case report. (PubMed)

Swallowing dynamics status post caustic ingestion in a pediatric patient: A multidisciplinary case report. A case report of a 10 year old male illustrates the effect of damage to the tongue base, hypopharynx, cricopharyngeus, and esophagus on the sensory and motor components of the swallowing mechanism. The characteristics of the dysphagia were manifested clinically, radiographically, and endoscopically. A myectomy was required to restore functional swallowing as scar tissue formation

2016 International Journal of Pediatric Otorhinolaryngology

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