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Cardiogenic Shock

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121. The cVAD registry for percutaneous temporary hemodynamic support: A prospective registry of Impella mechanical circulatory support use in high-risk PCI, cardiogenic shock, and decompensated heart failure. (Abstract)

The cVAD registry for percutaneous temporary hemodynamic support: A prospective registry of Impella mechanical circulatory support use in high-risk PCI, cardiogenic shock, and decompensated heart failure. Management of patients requiring temporary, mechanical hemodynamic support during high- risk percutaneous coronary intervention (PCI) or in cardiogenic shock is rapidly evolving. With the availability of the Impella 2.5, CP, 5.0, LD, and RP percutaneous mechanical circulatory support devices (...) , there is a need for continued surveillance of outcomes. Three factors underline the importance of a registry for these populations. First, large randomized trials of hemodynamic support, involving cardiogenic shock, are challenging to conduct. Second, there is increasing interest in the use of registries to provide "real-world" experience and to allow the flexibility to evaluate individual patient uses and outcomes. Third, current, large databases have not captured the specific impact of mechanical support

2018 American Heart Journal

122. Predictors of intra-aortic balloon pump hemodynamic failure in non-acute myocardial infarction cardiogenic shock. Full Text available with Trip Pro

Predictors of intra-aortic balloon pump hemodynamic failure in non-acute myocardial infarction cardiogenic shock. To characterize patient profile and hemodynamic profile of those undergoing intra-aortic balloon pump (IABP) for cardiogenic shock and define predictors of hemodynamic failure of IABP support.Clinical characteristics of IABP support in cardiogenic shock not related to acute myocardial infarction (AMI) remain poorly characterized.We retrospectively studied a cohort of 74 patients (...) from 2010 to 2015 who underwent IABP insertion for cardiogenic shock complicating acute decompensated heart failure not due to AMI.In the overall cohort, which consisted primarily of patients with chronic systolic heart failure (89%), IABP significantly augmented cardiac index and lowered systemic vascular resistance (P<.05). Despite this improvement, 28% of these patients died (24%) or require urgent escalation in mechanical circulatory support (MCS) (4%). Multivariable regression revealed

2018 American Heart Journal

123. Circulating microparticles are associated with clinical severity of persistent ST-segment elevation myocardial infarction complicated with cardiogenic shock. (Abstract)

Circulating microparticles are associated with clinical severity of persistent ST-segment elevation myocardial infarction complicated with cardiogenic shock. Cardiogenic shock (CS) is the leading cause of death in patients admitted for acute myocardial infarction (MI). Despite the recent advances in reperfusion and medical treatment mortality remains unacceptably high. Whether cells of the blood compartment in CS-patients are activated and release microparticles (cMPs) that may be both (...) microparticles (cMPs) are found in cardiogenic shock (CS) patients as compared to non-CS patients. In CS-patients, a higher number of platelet- and monocyte-cMPs and a higher number of tissue factor-rich cMPs were associated to worse myocardial reperfusion. A specific prothrombotic and proinflammatory cMPs signature in cardiogenic shock (CS) patients is a potential discriminator and survival prognostic biomarker for CS, which could aid management and improve clinical outcomes.Copyright © 2017 Elsevier B.V

2018 International journal of cardiology

124. Early Electroencephalography Findings in Cardiogenic Shock Patients Treated by Venoarterial Extracorporeal Membrane Oxygenation. (Abstract)

Early Electroencephalography Findings in Cardiogenic Shock Patients Treated by Venoarterial Extracorporeal Membrane Oxygenation. We aimed to assess early electroencephalography findings in patients treated by venoarterial extracorporeal membrane oxygenation and their association with neurologic outcome.Single-center observational study.Medical ICU of a university hospital.An early standardized electroencephalography assessment, that is, standard electroencephalography followed by continuous (...) electroencephalography, was performed in consecutive cardiogenic shock patients requiring venoarterial extracorporeal membrane oxygenation. Associations between electroencephalography findings and outcome, defined as a composite of acute brain injury or death at 14 days, were investigated.Twenty-two patients with a median Full Outline of Unresponsiveness score of 4 (interquartile range, 3-6) were studied. Pupillary light reflex, corneal reflex, and cough reflex were preserved in 20 (90%), 17 (77%), and 17 (77

2018 Critical Care Medicine

125. Percutaneous biventricular Impella support in therapy-refractory cardiogenic shock. (Abstract)

Percutaneous biventricular Impella support in therapy-refractory cardiogenic shock. Percutaneous mechanical circulatory support systems have increasingly been adopted as a bail out strategy in patients with cardiogenic shock. Since studies showed mostly mixed results, however, the use of support systems remains a case by case decision.Here, we report on a case of therapy-refractory cardiogenic shock due to acute myocardial infarction treated with percutaneous right and left ventricular assist (...) devices (Impella RP and CP).Due to myocardial stunning, even patients with fulminant cardiogenic shock have the potential for full recovery. In the present case, we demonstrate the feasibility of biventricular Impella support in therapy-refractory cardiogenic shock facilitating bridge to recovery.Copyright © 2018 Elsevier Inc. All rights reserved.

2018 Heart & Lung

126. National Cardiogenic Shock Initiative

National Cardiogenic Shock Initiative National Cardiogenic Shock Initiative - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. National Cardiogenic Shock Initiative (NCSI) The safety and scientific validity (...) provided by (Responsible Party): William W. O'Neill, Henry Ford Health System Study Details Study Description Go to Brief Summary: This study evaluates the use of early mechanical circulatory support in patients presenting with acute myocardial infarction and cardiogenic shock. Patients are treated according to the National Cardiogenic Shock Initiative protocol, which emphasizes early identification of cardiogenic shock and rapid delivery of mechanical circulatory support based on invasive hemodynamics

2018 Clinical Trials

127. Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock and Cardiac Arrest. Full Text available with Trip Pro

Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock and Cardiac Arrest. Venoarterial extracorporeal membrane oxygenation (VA-ECMO)-also referred to as extracorporeal life support-is a form of temporary mechanical circulatory support and simultaneous extracorporeal gas exchange. The initiation of VA-ECMO has emerged as a salvage intervention in patients with cardiogenic shock, even cardiac arrest refractory to standard therapies. Analogous to veno-venous ECMO for acute

2018 Circulation. Heart failure

128. Case report of dependent venous contrast pooling and layering in a patient without acute cardiogenic shock. Full Text available with Trip Pro

Case report of dependent venous contrast pooling and layering in a patient without acute cardiogenic shock. We present a case of incidental venous contrast pooling and layering in a patient without sudden cardiac arrest or cardiogenic shock.The patient presented with only discrete symptoms and did not suffer fatal cessation of the cardiac pump function during or shortly after the scan.The patient showed stigmata of venous gravity-dependent pooling and layering of contrast medium, which has (...) frequently been described as a sign of imminent cardiogenic shock and cardiac arrest.A cardiologic consultation including echocardiography was initiated.Echocardiography confirmed valvular heart disease and biventricular heart failure. A subsequent follow-up CT acquired 8 months after the incidental finding showed no signs of dependent contrast pooling.Pooling and layering of contrast medium can occur in patients not suffering acute fatal cessation of the cardiac pump function. Nonetheless, any signs

2018 Medicine

129. Lithium intoxication presenting as altered consciousness and arrhythmia with cardiogenic shock: A case report. Full Text available with Trip Pro

Lithium intoxication presenting as altered consciousness and arrhythmia with cardiogenic shock: A case report. Lithium has been used to treat bipolar disorder. Lithium has a narrow therapeutic index, with a therapeutic level between 0.6 and 1.5 mEq/L. The possible complications of lithium overdose include altered mental status, hand tremor, muscle weakness, nausea, vomiting, diarrhea, seizure, syncope, and arrhythmia. Lithium intoxication can be fatal and is difficult to diagnose in patients (...) , and blood pressure and consciousness level improved subsequently. The patient was discharged 9 days later in a stable condition.If an emergency physician encounters a patient with altered consciousness and arrhythmia with cardiogenic shock, the patient's drug intake history should be carefully reviewed to rule out cardiovascular problems on the basis of the patient's clinical condition.

2018 Medicine

130. In-hospital outcomes of percutaneous ventricular assist devices versus intra-aortic balloon pumps in non-ischemia related cardiogenic shock. (Abstract)

In-hospital outcomes of percutaneous ventricular assist devices versus intra-aortic balloon pumps in non-ischemia related cardiogenic shock. This study compared inpatient outcomes related to the use of these two devices among patients who developed cardiogenic shock not due to acute myocardial infarction or coronary revascularization.We extracted admission-level records of patients with a diagnosis of cardiogenic shock who underwent either PVAD or IABP implantation from the National Inpatient (...) Sample (NIS) database from 2010 to 2014. Our outcomes of interest were mortality and length of stay.Inpatient mortality was significantly higher in the PVAD cohort. In multivariate analysis, PVAD use in these patients was associated with higher mortality. There was no difference in the length of stay between both groups among patients that survived to discharge.In our analysis of the NIS database, the use of PVADs in patients with cardiogenic shock of non-ischemic origin was associated with higher

2018 Heart & Lung

131. A continuous-flow external ventricular assist device for cardiogenic shock: Evolution over 10 years. (Abstract)

A continuous-flow external ventricular assist device for cardiogenic shock: Evolution over 10 years. The use of percutaneous mechanical circulatory support (MCS) in the treatment of cardiogenic shock has increased. However, limitations in flow capability, ventricular unloading effect, durability, and mobility remain. We reviewed our single-center experience with continuous-flow external ventricular assist devices (VADs) to determine the role of temporary VADs for cardiogenic shock (...) continuous-flow external VAD in patients with refractory cardiogenic shock.Copyright © 2018 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

2018 Journal of Thoracic and Cardiovascular Surgery

132. Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients

Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03596944 Recruitment Status : Completed First Posted : July 24, 2018 Last Update Posted

2018 Clinical Trials

133. The Effects of IABP Prior to Revascularization on Mortality of ACS Patients Complicated With Cardiogenic Shock

The Effects of IABP Prior to Revascularization on Mortality of ACS Patients Complicated With Cardiogenic Shock The Effects of IABP Prior to Revascularization on Mortality of ACS Patients Complicated With Cardiogenic Shock - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. The Effects of IABP Prior to Revascularization on Mortality of ACS Patients Complicated With Cardiogenic Shock The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2018 Clinical Trials

134. Extracorporeal Life Support in Cardiogenic Shock

Extracorporeal Life Support in Cardiogenic Shock Extracorporeal Life Support in Cardiogenic Shock - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Extracorporeal Life Support in Cardiogenic Shock (ECLS-SHOCK (...) to no ECLS in patients with severe infarctrelated cardiogenic shock with respect to 30-day mortality Condition or disease Intervention/treatment Phase Acute Myocardial Infarction Cardiogenic Shock Procedure: ECLS insertion Other: Revascularisation and optimal medical treatment Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 420 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None

2018 Clinical Trials

135. Syncope and cardiogenic shock in an 80-year-old woman Full Text available with Trip Pro

Syncope and cardiogenic shock in an 80-year-old woman 29453215 2018 10 26 2018 11 13 1757-790X 2018 2018 Feb 16 BMJ case reports BMJ Case Rep Syncope and cardiogenic shock in an 80-year-old woman. bcr-2017-223924 10.1136/bcr-2017-223924 Obafemi Toba T Cardiology Department, University Hospital Aintree NHS trust, Liverpool, UK. Carline Nicola N Cardiology Department, University Hospital Aintree NHS trust, Liverpool, UK. Khand Aleem A Cardiology Department, University Hospital Aintree NHS trust (...) , Liverpool, UK. Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK. Cardiology Department, Liverpool Heart and Chest Hospital, Liverpool, UK. eng Case Reports Journal Article 2018 02 16 England BMJ Case Rep 101526291 1757-790X IM Aged, 80 and over Dyspnea etiology Female Humans Shock, Cardiogenic etiology Syncope etiology Takotsubo Cardiomyopathy complications diagnosis clinical diagnostic tests heart failure Competing interests: AK has the following potential conflicts

2018 BMJ case reports

136. Outcomes in Cardiogenic Shock Patients with Extracorporeal Membrane Oxygenation Use: A Matched Cohort Study in Hospitals across the United States Full Text available with Trip Pro

Outcomes in Cardiogenic Shock Patients with Extracorporeal Membrane Oxygenation Use: A Matched Cohort Study in Hospitals across the United States ECMO is increasingly used for patients with critical illnesses. This study examines ECMO use in patients with cardiogenic shock in US hospitals and associated outcomes (mortality, hospital length of stay, and total hospital charges).A matched cohort retrospective study was conducted using the 2013 Nationwide Emergency Department Sample. Cardiogenic (...) )) remained higher in the ECMO group, while LOS was similar (OR = 1.01 (95% CI: 0.99-1.02)).Patients with cardiogenic shock who underwent ECMO had increased mortality and higher cost of care without significant increase in LOS when compared to patients with cardiogenic shock without ECMO use. Prospective evaluation of this observed association is needed to improve outcomes and resources' utilization further.

2018 BioMed research international

137. Immediate non-culprit vessel percutaneous coronary intervention (PCI) in patients with acute myocardial infarction and cardiogenic shock: a swinging pendulum Full Text available with Trip Pro

Immediate non-culprit vessel percutaneous coronary intervention (PCI) in patients with acute myocardial infarction and cardiogenic shock: a swinging pendulum 29608190 2018 11 14 2072-1439 10 2 2018 Feb Journal of thoracic disease J Thorac Dis Immediate non-culprit vessel percutaneous coronary intervention (PCI) in patients with acute myocardial infarction and cardiogenic shock: a swinging pendulum. 661-666 10.21037/jtd.2018.01.106 Russo Juan J JJ University of Ottawa Heart Institute, Ottawa

2018 Journal of thoracic disease

138. Thyrotoxicosis induced cardiogenic shock rescued by extracorporeal membrane oxygenation Full Text available with Trip Pro

Thyrotoxicosis induced cardiogenic shock rescued by extracorporeal membrane oxygenation 29662515 2018 11 14 1671-5411 15 2 2018 Feb Journal of geriatric cardiology : JGC J Geriatr Cardiol Thyrotoxicosis induced cardiogenic shock rescued by extracorporeal membrane oxygenation. 203-204 10.11909/j.issn.1671-5411.2018.02.003 Kim Seunghwan S Department of Internal Medicine, INJE University College of Medicine, Haeundae Paik hospital, Busan, South Korea. Seol Sang-Hoon SH Department of Internal (...) of Internal Medicine, INJE University College of Medicine, Haeundae Paik hospital, Busan, South Korea. eng Journal Article China J Geriatr Cardiol 101237881 1671-5411 Cardiogenic shock Extracorporeal membrane oxygenation Thyrotoxic cardiomyopathy 2018 4 18 6 0 2018 4 18 6 0 2018 4 18 6 1 ppublish 29662515 10.11909/j.issn.1671-5411.2018.02.003 jgc-15-02-203 PMC5895961 Endocrinol Metab Clin North Am. 2006 Dec;35(4):663-86, vii 17127140 J Heart Lung Transplant. 2005 Jan;24(1):81-7 15653384 Eur J Endocrinol

2018 Journal of geriatric cardiology : JGC

139. Extracorporeal life support in cardiogenic shock: indications and management in current practice Full Text available with Trip Pro

Extracorporeal life support in cardiogenic shock: indications and management in current practice Veno-arterial extracorporeal life support (VA-ECLS) provides circulatory and respiratory stabilisation in patients with severe refractory cardiogenic shock. Although randomised controlled trials are lacking, the use of VA-ECLS is increasing and observational studies repeatedly have shown treatment benefits in well-selected patients. Current clinical challenges in VA-ECLS relate to optimal management (...) of the individual patient on extracorporeal support given its inherent complexity. In this review article we will discuss indications, daily clinical management and complications of VA-ECLS in cardiogenic shock refractory to conventional treatment strategies.

2018 Netherlands Heart Journal

140. Predictive Value of Procalcitonin for Infection and Survival in Adult Cardiogenic Shock Patients Treated with Extracorporeal Membrane Oxygenation Full Text available with Trip Pro

Predictive Value of Procalcitonin for Infection and Survival in Adult Cardiogenic Shock Patients Treated with Extracorporeal Membrane Oxygenation Procalcitonin (PCT) is a predictive marker for the occurrence of bacterial infection and the decision to terminate antibiotic treatment in critically ill patients. An unusual increase in PCT, regardless of infection, has been observed during extracorporeal membrane oxygenation (ECMO) support. We evaluated trends and the predictive value of PCT levels (...) in adult cardiogenic shock during treatment with ECMO. We reviewed the clinical records of 38 adult cardiogenic shock patients undergoing veno-arterial ECMO support between January 2014 and December 2016. The exclusion criteria were age <18 years, pre-ECMO infection, and less than 48 hours of support. The mean patient age was 56.7±14.7 years and 12 (31.6%) patients were female. The mean duration of ECMO support was 9.0±7.6 days. The rates of successful ECMO weaning and survival to discharge were 55.3

2018 Chonnam medical journal

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