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Canker Sore

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1. Treatment of recurrent aphthous stomatitis (RAS; aphthae; canker sores) with a barrier forming mouth rinse or topical gel formulation containing hyaluronic acid: a retrospective clinical study. Full Text available with Trip Pro

Treatment of recurrent aphthous stomatitis (RAS; aphthae; canker sores) with a barrier forming mouth rinse or topical gel formulation containing hyaluronic acid: a retrospective clinical study. Use of hyaluronic acid-based products has become a valuable alternative to drug-based approaches in the treatment of recurrent aphthous stomatitis (RAS). The presented study aimed to investigate the effect of a barrier forming hyaluronic acid containing mouth wash or a topical gel formulation (...) on the healing of RAS and patient's quality of life.For this single-center retrospective study, medical records of the Dental School of the University of Brescia were screened for adult and systemically health patients suffering from minor recurrent aphthous stomatitis (RAS) and treated with either a barrier forming, hyaluronic acid containing mouth wash (GUM® AftaClear® rinse) or a topical gel (GUM® AftaClear® gel) in 2015. All patients fulfilling the in-/exclusion criteria and presenting full data sets

2019 BMC Oral Health

2. Canker Sore

) May be useful in severe cases in HIV patients XII. References (2013) Presc Lett 20(1): 4 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Canker Sore." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Aphthous Stomatitis (C0038363) Definition (MEDLINEPLUS) Canker sores are small, round sores on the inside of the cheek, under the tongue (...) Ulcer , Canker Sore , Sore, Canker , Sores, Canker , Stomatitides, Aphthous , Stomatitis, Aphthous , Ulcer, Aphthous , Ulcers, Aphthous , Aphthous Stomatitis , CANKER SORES ORAL , STOMATITIS APHTHOUS , ULCERS APHTHOUS ORAL , aphthous stomatitis , Oral aphthae NOS , Ulcerative stomatitis NOS , Oral aphthous ulcer , Aphthous stomatitis , Canker sore , Aphthous ulceration , Aphthous ulcer , Aphthous ulcer of mouth , Aphthous ulcer of mouth (disorder) , Oral aphthae , Aphthous ulcers , aphthous ulcer

2018 FP Notebook

3. Duration and Intensity of Anesthetic Effect Produced by Canker Sore Medications. (Abstract)

Duration and Intensity of Anesthetic Effect Produced by Canker Sore Medications. Canker sore medications are often recommended to patients for relief of pain associated with aphthous ulcers or other minor irritations of the mouth. The anesthetic effect of these medications is achieved by incorporation of local anesthetics, such as benzocaine, into the products' formulations. To determine the duration and intensity of the anesthetic effect of benzocaine-containing products, three topical oral (...) health care medications, Red Cross Canker Sore Medication, Maximum Strength Anbesol and Orajel Mouth Aid, were compared. In this double blind cross-over study, each product was tested on 21 subjects with normal mucosa and gingiva. All three products produced anesthetic effects. Red Cross Canker Sore Medication was shown to have the longest duration and greatest intensity.

2015 The Journal of clinical dentistry Controlled trial quality: uncertain

4. "Ozone" - the new NEMESIS of canker sore. Full Text available with Trip Pro

"Ozone" - the new NEMESIS of canker sore. Recurrent aphthous ulceration or recurrent aphthous stomatitis is one of the most debilitating and painful oral mucosal disease. This disease entity has no specific cause to occur and no proper laboratory procedures are present to elicit the diagnosis. The treatment options are largely palliative and aimed at reducing symptoms thereby improving patient's oral condition. In the present study the subjects witnessed alleviation of clinical symptoms related (...) to the aphthous ulceration.The aim of the study was to explore the effectiveness of ozonated oil in the treatment of recurrent aphthous ulcer and to compare with sessame oil in order to analyse the effectiveness between the two topical oil medications.A single-blinded placebo-controlled trial comprising of 30 subjects with recurrent aphthous ulcers were divided into Group 1, Group 2 and Group 3 with 10 subjects in each group was performed. Patients in Group 1 received ozonated oil, Group 2 received sesame oil

2015 Journal of clinical and diagnostic research : JCDR Controlled trial quality: uncertain

5. SINGLE APPLICATION OF A DESSICATING AGENT IN THE TREATMENT OF RECURRENT APHTHOUS STOMATITIS. (Abstract)

SINGLE APPLICATION OF A DESSICATING AGENT IN THE TREATMENT OF RECURRENT APHTHOUS STOMATITIS. Recurrent aphtous stomatitis (aphthae, canker sores) is ones of the most common and painful oral mucosal inflammatory ulcerative conditions; etiopathogenesis is uncertain and only symptomatic therapy is available. We used a dessicating agent based on a concentrated mixture of sulfates. The rationale for use of this product on canker sores is that it cauterises the epithelial tissue affected (...) by the immune response. The aim of this study was to evaluate the topical application of this dessicating agent on aphtous ulcers, and verify its efficacy in reducing pain. Fifty-seven patients, with oral minor aphtous lesions and a history of recurrent aphtous stomatitis were enrolled into this study and were assigned into two groups: 30 patients were treated with a single topical application of a dessicating agent and 27 without any treatment. A subjective evaluation of symptoms was completed by each

2019 Journal of biological regulators and homeostatic agents Controlled trial quality: uncertain

6. Topical Aloe Vera is effective in treating Recurrent Minor Aphthous Stomatitis

is a commonly occurring oral disease, causing severe discomfort. The results obtained from this study allow us to use Aloe Vera gel safely in the clinical setting for patients presenting with recurrent minor aphthous stomatitis. Specialty/Discipline (Oral Medicine/Pathology/Radiology) (General Dentistry) (Pediatric Dentistry) (Dental Hygiene) Keywords Recurrent aphthous stomatitis, therapy, Aloe Vera, canker sores ID# 2481 Date of submission: 05/22/2013 E-mail meenachi.sellappan@ucdenver.edu Author Meenachi (...) Topical Aloe Vera is effective in treating Recurrent Minor Aphthous Stomatitis UTCAT2481, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Topical Aloe Vera is effective in treating Recurrent Minor Aphthous Stomatitis Clinical Question Does treatment with 2% Aloe Vera gel in a patient with recurrent minor aphthous stomatitis decrease perceived pain, size of the lesion and duration of healing compared to a placebo

2013 UTHSCSA Dental School CAT Library

7. Canker Sore

) May be useful in severe cases in HIV patients XII. References (2013) Presc Lett 20(1): 4 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Canker Sore." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Aphthous Stomatitis (C0038363) Definition (MEDLINEPLUS) Canker sores are small, round sores on the inside of the cheek, under the tongue (...) Ulcer , Canker Sore , Sore, Canker , Sores, Canker , Stomatitides, Aphthous , Stomatitis, Aphthous , Ulcer, Aphthous , Ulcers, Aphthous , Aphthous Stomatitis , CANKER SORES ORAL , STOMATITIS APHTHOUS , ULCERS APHTHOUS ORAL , aphthous stomatitis , Oral aphthae NOS , Ulcerative stomatitis NOS , Oral aphthous ulcer , Aphthous stomatitis , Canker sore , Aphthous ulceration , Aphthous ulcer , Aphthous ulcer of mouth , Aphthous ulcer of mouth (disorder) , Oral aphthae , Aphthous ulcers , aphthous ulcer

2015 FP Notebook

8. Relief of Canker Sores on Resumption of Cigarette Smoking Full Text available with Trip Pro

Relief of Canker Sores on Resumption of Cigarette Smoking 18732340 2008 08 29 2018 11 13 0008-1264 93 4 1960 Oct California medicine Calif Med Relief of Canker Sores on Resumption of Cigarette Smoking. 235-6 Bookman R R eng Journal Article United States Calif Med 0410260 0008-1264 1960 10 1 0 0 1960 10 1 0 1 1960 10 1 0 0 ppublish 18732340 PMC1578433 J Allergy. 1958 Sep;29(5):442-5 13575065 J Allergy. 1958 Sep;29(5):438-41 13575064 J Allergy. 1956 Nov;27(6):536-43 13366556 Calif Med. 1955 May

1960 California Medicine

9. Aphthous Stomatitis (Overview)

14, 2018 Author: Ginat W Mirowski, MD, DMD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Aphthous Stomatitis Overview Background Aphthous stomatitis, also known as recurrent aphthous ulcers or canker sores, is among the most common oral mucosal lesion physicians and dentists observe. Aphthous stomatitis is a disorder of unknown etiology that may cause significant morbidity. One or several discrete, shallow, painful ulcers are visible on the unattached oral (...) Aphthous Stomatitis (Overview) Aphthous Stomatitis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA3NTU3MC1vdmVydmlldw== processing > Aphthous Stomatitis Updated: May

2014 eMedicine.com

10. Aphthous Stomatitis (Diagnosis)

14, 2018 Author: Ginat W Mirowski, MD, DMD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Aphthous Stomatitis Overview Background Aphthous stomatitis, also known as recurrent aphthous ulcers or canker sores, is among the most common oral mucosal lesion physicians and dentists observe. Aphthous stomatitis is a disorder of unknown etiology that may cause significant morbidity. One or several discrete, shallow, painful ulcers are visible on the unattached oral (...) Aphthous Stomatitis (Diagnosis) Aphthous Stomatitis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA3NTU3MC1vdmVydmlldw== processing > Aphthous Stomatitis Updated: May

2014 eMedicine.com

11. Recurrent aphthous stomatitis: genetic aspects of etiology Full Text available with Trip Pro

Recurrent aphthous stomatitis: genetic aspects of etiology Recurrent aphthous stomatitis (RAS; recurrent aphthous ulcers - RAU; canker sores) is a chronic inflammatory, ulcerative condition of the oral mucosa. Its prevalence in the general population ranges between 5% and 20%, depending on the method and group studied. The etiopathogenesis of the disease is considered to be multifactorial, but remains still not fully understood. In patients with RAS, an enhanced immunologic response occurs (...) to some trigger factors that may include: mechanical injury, stress or bacterial and viral antigens. Higher prevalence of aphthae in relatives may also indicate the genetic background of the condition. The inheritance of some specific gene polymorphisms, especially those encoding proinflammatory cytokines, which play a role in the formation of aphthous ulcer, may predispose family members to RAS. The purpose of this paper was to present the main clinical features of recurrent aphthous stomatitis

2013 Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii

12. Etiopathogenesis of Recurrent Aphthous Stomatitis and the Role of Immunologic Aspects: Literature Review Full Text available with Trip Pro

Etiopathogenesis of Recurrent Aphthous Stomatitis and the Role of Immunologic Aspects: Literature Review Recurrent aphthous stomatitis (RAS; recurrent aphthous ulcers; canker sores) belongs to the group of chronic, inflammatory, ulcerative diseases of the oral mucosa. Up to now, the etiopathogenesis of this condition remains unclear; it is, however, considered to be multifactorial. The results of currently performed studies indicate that genetically mediated disturbances of the innate

2013 Archivum Immunologiae et Therapiae Experimentalis

13. Levamisole treatment of a child with severe aphthous stomatitis and neutropenia. Full Text available with Trip Pro

Levamisole treatment of a child with severe aphthous stomatitis and neutropenia. The treatment of a 12-year-old girl with a lifelone history of recurrent infections and aphthous stomatitis is reported. A profound neutropenis, first noted at the age of 2 years, occurring at least every month was observed together with multiple mouth ulcers a sore throat and swelling of the jugular glands. Levamisole, originally described as an anthelmintic, has a beneficial effect on the symptoms of recurrent (...) aphthous stomatitis. After levamisole treatment aphthous stomatitis was milder and in the 1-year follow-up period the patient was asymptomatic several times during a phase of obvious neutrophil depression. The child no longer complained of a sore throat with swelling of the jugular glands and the recurrent staphylococcal infections of the skin disappeared. After therapy a marked increase in monocytes at the moment of neutropenia was observed.

1976 Postgraduate medical journal

14. Oral aphthous ulcers

Oral aphthous ulcers Oral aphthous ulcers - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Oral aphthous ulcers Last reviewed: February 2019 Last updated: July 2018 Summary Clinically, 3 forms of recurrent aphthous ulceration exist: major, minor, and herpetiform. Recurrent aphthous stomatitis is distinguished from aphthous-like ulceration by exclusion of underlying systemic conditions (e.g., Behcet's syndrome, HIV (...) /AIDS, or cyclic neutropenia). Diagnosis is based on the history and clinical examination with exclusion of a systemic aetiology; there are no specific laboratory findings. Topical corticosteroids and anti-inflammatory agents are the mainstay of treatment. Severe or refractory cases may require systemic therapy. Definition Recurrent aphthous stomatitis (RAS) is a common condition of the oral mucosa that presents in patients who are otherwise healthy. It is characterised by multiple, erythematous

2018 BMJ Best Practice

15. Mouth Care

Fungal infections The most common types are candidiasis, denture stomatitis and angular cheilitis. Maintain oral hygiene by following advice. Refer to Oral hygiene care. In many cases a systemic antifungal such as fluconazole (capsules or suspension) 50mg daily for 7 days will be indicated (review and extend as necessary). Practice point: Refer for dental opinion if no improvement in 7 day period. Topical miconazole oral gel should be considered for treating angular cheilitis (soreness, redness (...) ), aphthous ulceration, oral malignancy and mucositis. Gelclair ® is a viscous gel specially formulated to aid in the management of lesions of the oral mucosa. It forms a protective film that, by coating and sticking to the lining of the mouth and throat, offers rapid and effective pain management. Practice point: The contents of one sachet should be diluted with 40ml of water and used as a mouthwash. This should be repeated three times a day 1 hour before eating or drinking. Management of oral infections

2018 Scottish Palliative Care Guidelines

16. Guidelines for the Management of Genital Herpes in New Zealand

of the genital region; speculum examination should be considered, but may need to be delayed if discomfort is anticipated. Diagnosis Laboratory confirmation of the diagnosis is important, but should not delay the initiation of treatment. A negative result does not necessarily exclude a diagnosis of HSV (see page 8-9). Differential diagnosis • Aphthous ulcers. There are fewer and larger lesions with no preceding vesicles. • Steven Johnson syndrome. This is usually but not always associated with skin lesions

2017 New Zealand Sexual Health Society

17. Oral Aphthous Ulcer - Guidelines for Prescribing Triamcinolone Dental Paste

Oral Aphthous Ulcer - Guidelines for Prescribing Triamcinolone Dental Paste Oral Aphthous Ulcer - Guidelines for Prescribing Triamcinolone Dental Paste - medSask Home - College of Pharmacy and Nutrition - University of Saskatchewan Toggle Menu Search the U of S Search Oral Aphthous Ulcer - Guidelines for Prescribing Triamcinolone Dental Paste Mouth ulcers, also known as canker sores, aphthous ulcers or aphthous stomatitis are painful, recurrent lesions which occur on oral mucosa, especially (...) for these guidelines. Only the active ingredients in the "products" section are approved for pharmacist prescribing. McCartan BE, Sullivan A. The association of menstrual cycle, pregnancy, and menopause with recurrent oral aphthous stomatitis : a review and critique. Obstet Gynecol. 1992;80(3 Pt 1):455-8. . Published September 1992. Markarian A. Aphthous Ulcers (Canker Sores). In: Compendium of Therapeutics for Minor Ailments. Ottawa, ON: Canadian Pharmacists Association; 2014. Available from: . Subscription

2017 medSask

18. Palliative care - oral

required. Tests which should be considered include: Full blood count if neutropenia is suspected. Platelet count if spontaneous bleeding accompanies chemotherapy-induced mucositis. Iron, folate, and vitamin B12 levels if there is recurrent aphthous ulceration. A swab to check for candida infection if clinical features are suggestive. If there is persistent or recurrent oral candidiasis species typing and sensitivity testing may be helpful. Advice should be offered on measures to prevent oral problems (...) mouth. Topical non-opioid analgesia for mild to moderate oral pain, and combined topical and systemic analgesia for severe oral pain. Topical corticosteroids and doxycyline mouthwash for aphthous ulcers; topical or oral aciclovir for oral herpes simplex infection. Referral should be considered or a specialist contacted for advice if there is: Concern about oral intake and nutrition. Refractory oral pain or excessive salivation. Severe mucositis. Suspected neutropenic ulcers. Severe, persistent

2018 NICE Clinical Knowledge Summaries

19. Tonsillectomy in Children

, cervical adenopathy, tonsillar exudate, or positive test for group A beta-hemolytic streptococcus. The child with recurrent throat infection who does not meet the criteria above should be assessed for modifying factors that may nonetheless favor tonsillectomy, such as multiple antibiotic allergy/intolerance, PFAPA (periodic fever, aphthous stomatitis, pharyngitis and adenitis), or history of >1 peritonsillar abscess. Caregivers of children with obstructive sleep-disordered breathing and tonsil (...) recommended if there have been fewer than 7 episodes in the past year, fewer than 5 episodes per year in the past 2 years, or fewer than 3 episodes per year in the past 3 years. Tonsillectomy may be considered for recurrent throat infection with a frequency of at least 7 episodes in the past year or at least 5 episodes per year for 2 years or at least 3 episodes per year for 3 years with documentation in the medical record for each episode of sore throat and 1 or more of the following: temperature >38.3°C

2016 American Academy of Family Physicians

20. Aphthous ulcer

for biopsy to rule out malignancy. Have I got the right topic? Have I got the right topic? From age 5 years onwards. This CKS topic covers the management of aphthous ulcers. These are also known as aphthous stomatitis, aphthae, or canker sores. This CKS topic does not cover the management of ulceration due to infection with the herpes simplex virus, or ulcers due to other causes. There are separate CKS topics on , (which includes cold sores), , and . The target audience for this CKS topic is healthcare (...) process can be found in the section and on the website. Search strategy Search strategy Scope of search A literature search was conducted for guidelines, systematic reviews and randomized controlled trials on primary care management of aphthous ulcer. Search dates August 2012 - July 2017. Key search terms Various combinations of searches were carried out. The terms listed below are the core search terms that were used for Medline. exp Stomatitis, Aphthous/, aphthous ulcer.tw., mouth ulcer.tw., canker

2017 NICE Clinical Knowledge Summaries

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