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Cancer Survivor Care

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4861. Models for delivering survivorship care. (PubMed)

Models for delivering survivorship care. Survivors of adult cancer face lifetime health risks that are dependent on their cancer, cancer treatment exposures, comorbid health conditions, genetic predispositions, and lifestyle behaviors. Content, intensity, and frequency of health care that addresses these risks vary from survivor to survivor. The aims of this article are to provide a rationale for survivor health care and to articulate a taxonomy of models of survivor care that is applicable

2006 Journal of Clinical Oncology

4862. Medical and nursing education and training opportunities to improve survivorship care. (PubMed)

Medical and nursing education and training opportunities to improve survivorship care. Improving the quality of care for cancer survivors is contingent on having physicians, nurses, and other professionals with adequate training in survivorship care. Previous literature has documented the deficiencies in existing formal education programs regarding the complex needs of this growing population. Continuing education programs and basic curricula need to incorporate the expanding body of knowledge (...) regarding the physiologic and psychosocial sequelae of survivorship. This article reviews the current status of survivorship education and provides direction for essential content in future education. Topics such as prevention of secondary cancers, long-term complications, rehabilitation services, quality-of-life issues, pain and symptom management, and treatment of recurrent cancer are critical competencies of education that should then become routine care for cancer survivors.

2006 Journal of Clinical Oncology

4863. A Study of Survivorship Service Capacities Among Health Care Agencies in New York City

SCREENER Detailed Description: To describe the range of services available to cancer survivors in the NYC area. To determine organizations' need for assistance to enhance services for survivors. Study Design Go to Layout table for study information Study Type : Observational Time Perspective: Prospective Official Title: A Study of Survivorship Service Capacities Among Health Care Agencies in New York City Study Start Date : April 2005 Actual Primary Completion Date : April 2009 Actual Study Completion (...) Cancer Center Collaborator: NYS DEPT HEALTH CANCER SVC PRO Information provided by (Responsible Party): Memorial Sloan Kettering Cancer Center Study Details Study Description Go to Brief Summary: To describe the range of services available to cancer survivors in the NYC area. To determine organizations' need for assistance to enhance services for survivors. Condition or disease Intervention/treatment All Cancers Behavioral: we will screen potential agencies using our CALL SCRIPT and our AGENCY

2007 Clinical Trials

4864. Health care costs in the last year of life--the Dutch experience. (PubMed)

. This paper has four objectives: (1) to estimate health care costs in the last year of life in the Netherlands; (2) to describe age patterns and differences between causes of death for men and women; (3) to compare cost profiles of decedents and survivors; and (4) to use these figures in projections of future health expenditure. We used health insurance data of 2.1 million persons (13% of the Dutch population), linked at the individual level with data on the use of home care and nursing homes and causes (...) of death in 1999. On average, health care costs amounted to 1100 Euro per person. Costs per decedent were 13.5 times higher and approximated 14,906 Euro in the last year of life. Most costs related to hospital care (54%) and nursing home care (19%). Among the major causes of death, costs were highest for cancer (19,000 Euro) and lowest for myocardial infarctions (8068 Euro). Between the other causes of death, however, cost differences were rather limited. On average costs for the younger decedents were

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2006 Social Science & Medicine

4865. Readmission to intensive care unit after initial recovery from major thoracic oncology surgery. (PubMed)

Readmission to intensive care unit after initial recovery from major thoracic oncology surgery. Little has been published regarding outcomes subsequent to complications after thoracic surgery. The present study investigated outcomes and risk factors associated with mortality in patients admitted to an intensive care unit (ICU) after initial recovery from thoracic oncology surgery.From March 2001 to August 2005, 1,087 patients underwent major resection for lung or esophageal cancer. Ninety-four (...) (8.6%) of those patients required ICU care after initial recovery, and were the subject of the present retrospective review.The patient group included 85 males (90.4%), of mean age 66 years. Patients were classified as either survivors (n = 63, 67%) or nonsurvivors (n = 31, 33%). The most common reason for ICU readmission was pulmonary complication (n = 73, 77.7%). Sixty-four patients (68.1%) required mechanical ventilation and 42 (43.3%) required renal support. Multivariate analysis showed

2007 Annals of Thoracic Surgery

4866. Genetic alterations in patients with esophageal cancer with short- and long-term survival rates after curative esophagectomy. (PubMed)

result in poor prognosis. Careful follow-up testing for double cancer is needed in long-term survivors of esophageal cancer. (...) Genetic alterations in patients with esophageal cancer with short- and long-term survival rates after curative esophagectomy. The objective of this study was to ascertain the exact relation between specific oncogenes and long- and short-term survival rates in patients with esophageal cancer.Recent developments in molecular biology have shown that several oncogenes and suppressor genes are involved in the development of esophageal cancer. However, the role of these genes still is unknown.The

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1997 Annals of Surgery

4867. Diet and Exercise-Based Counseling Program Compared With a Standard Counseling Program in Patients With Early-Stage Prostate Cancer

or polyunsaturates). Compare the health and quality of life of patients treated with these interventions. OUTLINE: This is a randomized, multicenter study. Patients are randomized to 1 of 2 treatment arms. Arm I: Patients participate in a computer-tailored, correspondence course comprising personalized diet and exercise intervention and other health information over a 10-month period. Arm II: Patients receive usual care comprising standardized print materials related to diet, exercise, cancer, and other (...) may undergo blood draw to test for substances related to fruit and vegetable intake and measurement of height and weight. Patients may also be asked to wear a pedometer for a 1-week period. PROJECTED ACCRUAL: A total of 530 patients will be accrued for this study. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Allocation: Randomized Primary Purpose: Other Official Title: Fresh Start: Promoting Health in Prostate Cancer Survivors Study Start Date

2002 Clinical Trials

4868. Quality of Life in Children Treated for Cancer

: Cross-Sectional Official Title: Assessment of Health/Quality of Life in Survivors of Childhood Cancer Study Start Date : April 2000 Actual Primary Completion Date : March 2003 Actual Study Completion Date : September 2006 Resource links provided by the National Library of Medicine resources: Groups and Cohorts Go to Group/Cohort Intervention/treatment Quality of life forms Completion of the development of an instrument [Minneapolis-Manchester Quality of Life (MM-QOL)] that measures HRQOL (...) in the survivors of childhood cancer in a standardized, valid way and to assess the feasibility of incorporating this endpoint in a variety of clinical trials. Other: Quality of Life Forms Completion of the instrument [Minneapolis-Manchester Quality of Life (MM-QOL)] that measures HRQOL in the survivors of childhood cancer in a standardized, valid way and to assess the feasibility of incorporating this endpoint in a variety of clinical trials. Outcome Measures Go to Primary Outcome Measures : Quality of life

2000 Clinical Trials

4869. Morbidity Following the Diagnosis and Treatment of Patients With Breast Cancer

of morbidities in a population of approximately 160 patients diagnosed with breast cancer before and after medical and surgical treatment. Subjects will be followed for one-year with quarterly examinations (baseline [pre-medical treatment] and at 1, 3 months, 6 months, 9 months and 12 months after treatment). In order for cancer survivors to understand the risk of impairment and functional limitations, and disability; and for health care providers to determine the risk of physical impairment, functional (...) Following the Diagnosis and Treatment of Patients With Breast Cancer: A Multi-Institutional Study Between the National Institutes of Health (NIH) Rehabilitation Medicine Department (RMD) and the Walter Reed National Military Medical Center (WRNMMC) Breast Care Center Study Start Date : November 16, 2001 Study Completion Date : August 17, 2016 Resource links provided by the National Library of Medicine related topics: related topics: Groups and Cohorts Go to Outcome Measures Go to Primary Outcome

2001 Clinical Trials

4870. Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer

Detailed Description: OBJECTIVES: I. Determine whether enalapril treatment results in a reduction in body surface area-adjusted left ventricular mass in anthracycline-treated survivors of childhood cancer. II. Determine whether improvement in ventricular function achieved by enalapril is sustained and alters the course of late cardiotoxicity. III. Determine the impact of enalapril therapy on quality of life. OUTLINE: This is a double blind, placebo controlled, randomized study. Patients are stratified (...) ) Actual Enrollment : 13 participants Allocation: Randomized Intervention Model: Single Group Assignment Masking: Double Primary Purpose: Supportive Care Official Title: Afterload Reduction Therapy for Late Anthracycline Cardiotoxicity: A Pediatric Oncology Group Cancer Control Study Study Start Date : September 2000 Actual Primary Completion Date : July 2003 Actual Study Completion Date : March 2007 Resource links provided by the National Library of Medicine available for: Arms and Interventions Go

1999 Clinical Trials

4871. Quality-of-Life Study of Patients With Previously Treated Ovarian Cancer

) Information provided by: Gynecologic Oncology Group Study Details Study Description Go to Brief Summary: RATIONALE: Quality-of-life assessment of patients undergoing cancer treatment may help determine the intermediate- and long-term effects of treatment in patients with cancer. PURPOSE: This clinical trial studies the quality of life in patients with previously treated ovarian cancer. Condition or disease Intervention/treatment Ovarian Cancer Procedure: psychosocial assessment and care Procedure: quality (...) -of-life assessment Detailed Description: OBJECTIVES: I. Compare quality of life in terms of health status, sexual functioning, psychological/emotional well being, and social functioning in ovarian germ cell cancer survivors vs a matched healthy control group. II. Predict quality of life in these patients through the additive effects of cancer diagnosis and treatment, sociodemographic characteristics, other stressors, and social network variables. OUTLINE: Patients identify up to 3 healthy acquaintance

1999 Clinical Trials

4872. Raloxifene With or Without Exercise Compared With Exercise Alone in Women Who Have Been Previously Treated for Breast Cancer

(Clinical Trial) Actual Enrollment : 80 participants Allocation: Randomized Primary Purpose: Supportive Care Official Title: Breast Cancer Survivors: Exercise and Raloxifene Study Start Date : March 2001 Actual Primary Completion Date : April 2003 Actual Study Completion Date : April 2003 Resource links provided by the National Library of Medicine related topics: related topics: available for: Arms and Interventions Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National (...) : Completed First Posted : August 6, 2003 Last Update Posted : May 28, 2012 Sponsor: OHSU Knight Cancer Institute Collaborator: National Cancer Institute (NCI) Information provided by (Responsible Party): OHSU Knight Cancer Institute Study Details Study Description Go to Brief Summary: RATIONALE: Raloxifene and exercise may improve bone health and quality of life in breast cancer survivors. Assessing bone health and quality of life may improve the ability to plan treatment. PURPOSE: Randomized clinical

2002 Clinical Trials

4873. Medical students' perceptions of children: modifying a childhood cancer stereotype. (PubMed)

of child survivors of cancer and one half were not given information. MANOVAs revealed that medical students in the information condition did not evidence any biases toward RLL children. However, RLL children were rated more negatively than HL children on several dimensions by 1st- and 4th-year students who did not participate in the intervention. The results suggest that a childhood cancer stereotype can be eliminated; however, standard medical training does not reduce the negative expectations health (...) care providers hold toward children diagnosed with cancer.

1991 Journal of pediatric psychology

4874. Promoting early detection tests for colorectal carcinoma and adenomatous polyps: a framework for action: the strategic plan of the National Colorectal Cancer Roundtable. (PubMed)

) was founded in 1997 by the American Cancer Society and the Centers for Disease Control and Prevention to provide strategic leadership, advocacy, long-range planning, and coordination of interventions targeted at reducing the disease burden of CRC through education, early detection, and prevention. The NCCRT and its three workgroups include CRC survivors; recognized experts in primary care, gastroenterology, radiology, colorectal surgery, nursing, public policy, epidemiology, and behavioral science (...) Promoting early detection tests for colorectal carcinoma and adenomatous polyps: a framework for action: the strategic plan of the National Colorectal Cancer Roundtable. The purpose of the current study was to provide health professionals, professional organizations, policy makers, and the general public with a practical blueprint for increasing the practice of screening for colorectal carcinoma (CRC) and adenomatous polyps over the next decade. The National Colorectal Cancer Roundtable (NCCRT

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2002 Cancer

4875. Time and place for sputum cytology in the diagnosis of lung cancer. (PubMed)

Time and place for sputum cytology in the diagnosis of lung cancer. Despite ready access to medical care 91% of patients dying of lung cancer derived from a population of just under 400 000 are shown to have presented too late for other than palliative treatment. As the incidence and death rates from lung cancer in the district were very similar, few survivors can be expected. Morphological confirmation of the diagnosis was available in 96% of cases. The first positive morphological diagnosis

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1981 Thorax

4876. Treatment of the terminal stages of breast cancer. (PubMed)

proportion of women who died than of women who survived received treatment at the last follow up visit, and 2.6 times as many of those dying within one week of the last visit were given chemotherapy as were survivors with recurrent disease. Resources devoted to diagnostic investigations and treatment of cancer in terminally ill patients could be better used for care of the patients. This would be more likely to improve the patients' quality of life and conserve resources. (...) Treatment of the terminal stages of breast cancer. To assess the intensity of and changes in diagnostic investigations and treatment in the terminal stages of breast cancer 555 patients in the area of Tampere University Central Hospital in whom breast cancer had been diagnosed from 1977 to 1980 were followed up for five years. The case notes for the last visit of 519 patients were analysed. The amount of diagnostic activity was similar for those who died and for the survivors. A higher

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1989 BMJ : British Medical Journal

4877. Ovarian cancer screening in women with a family history of breast or ovarian cancer. (PubMed)

Ovarian cancer screening in women with a family history of breast or ovarian cancer. To evaluate positive predictive values of CA 125 or transvaginal ultrasonography screening for ovarian cancer according to family history of breast or ovarian cancer.In the screening arm of a randomized controlled trial of screening compared with usual care, 28,460 women with family history data received baseline and annual CA 125 and transvaginal ultrasonography examinations. We analyzed CA 125 (...) screening results. Higher-risk women were more likely than lower-risk women to undergo biopsy after a positive screen. Screening identified 43 invasive ovarian cancers. The positive predictive values for abnormal screening results were 0.7% in average-risk, 1.3% in moderate-risk, and 1.6% in high-risk groups; one ovarian cancer occurred among the breast cancer survivors. The positive predictive values for postbaseline abnormal screening results were also higher in the higher-risk groups. The positive

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2006 Obstetrics and Gynecology

4878. A Study to Determine the Clinical Significance of Molecular Detection of Breast Cancer in the Blood of Stage IV Breast Cancer Patients

Trial) Actual Enrollment : 224 participants Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Basic Science Official Title: Peripheral Blood Molecular Staging of Breast Cancer: A Prospective Cohort Study Designed to Determine the Clinical Significance of Molecular Detection of Breast Cancer in the Peripheral Blood of Stage IV Breast Cancer Patients Study Start Date : November 2005 (...) -breast malignancy is eligible for this study only if the patient meets the following criteria for a cancer survivor. A cancer survivor is eligible provided the following criteria are met: (1) patient has undergone potentially curative therapy for all prior malignancies, (2) patients have been considered disease free for at least 5 years (with the exception of basal cell or squamous cell carcinoma of the skin or carcinoma-in-situ of the cervix). Inclusion Criteria - Healthy volunteers A volunteer

2006 Clinical Trials

4879. The intersection of cancer and aging: establishing the need for breast cancer rehabilitation. (PubMed)

The intersection of cancer and aging: establishing the need for breast cancer rehabilitation. The increasing success of treatments for common cancers has resulted in growing awareness of the unique health care needs of cancer survivors. Cancer treatments can be toxic and have long-lasting effects on health, potentially accelerating the aging process and producing associated declines in physical function. In this synthesis of the literature, we critically examine the strength of existing (...) changes associated with both aging and cancer treatment are reviewed. Parallels are proposed between existing preventive and rehabilitative programs and possibilities for similar interventions aimed at preventing, reversing, or halting declines in physical function in cancer survivors. Finally, a program of research is proposed to evaluate whether there is some subset of breast cancer survivors for whom prevention or rehabilitation of functional status declines is needed, as well as development

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2007 Cancer Epidemiology & Biomarkers and Prevention

4880. Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations. (PubMed)

Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations. Cancer survivors constitute 3.5% of the United States population, but second primary malignancies among this high-risk group now account for 16% of all cancer incidence. Although few data currently exist regarding the molecular mechanisms for second primary cancers and other late outcomes after cancer treatment, the careful measurement and documentation of potentially carcinogenic (...) ; 3) development of new technology, bioinformatics, and biomarkers; 4) design of new epidemiologic methods; and 5) development of evidence-based clinical practice guidelines. Many of the infrastructure resources and design strategies that would facilitate research in this area also provide a foundation for the study of other important nonneoplastic late effects of treatment and psychosocial concerns among cancer survivors. These research areas warrant high priority to promote NCI's goal

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2006 Journal of the National Cancer Institute

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