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1. Harmonization of delirium severity instruments: a comparison of the DRS-R-98, MDAS, and CAM-S using item response theory. (PubMed)

Harmonization of delirium severity instruments: a comparison of the DRS-R-98, MDAS, and CAM-S using item response theory. This study aimed to describe the level of agreement of three commonly used delirium instruments: the Delirium Rating Scale-Revised-98 (DRS-R-98), Memorial Delirium Assessment Scale (MDAS), and Confusion Assessment Method-Severity (CAM-S).We used data from a prospective clinical research study, in which a team of trained lay interviewers administered each instrument along

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2018 BMC medical research methodology

2. Not all cancer patients with an interest in CAM are the same. Differences between patients with a CAM interest prior to the cancer diagnosis and those with first-time interest since diagnosis. (PubMed)

Not all cancer patients with an interest in CAM are the same. Differences between patients with a CAM interest prior to the cancer diagnosis and those with first-time interest since diagnosis. The aim was to assess differences in age, gender, education and personality (Big Five) between cancer patients already interested in CAM prior to the diagnosis and cancer patients only interested in CAM since their diagnosis.323 members of the support and information platform "Lebenshaus e.V (...) ." with gastrointestinal stromal tumours (GIST), renal cell carcinomas (RCC) and sarcomas participated in an online survey.Interest in CAM prior to cancer diagnosis, CAM interest since diagnosis, CAM use and disclosure of CAM use to doctors.39% were already interested in CAM before the diagnosis and 40.6% were first interested in CAM after their diagnosis. 44.9% stated a current/past CAM use. Female gender and high education were significant predictors for interest in CAM before the diagnosis and general CAM use

2019 Complementary Therapies In Medicine

3. The REFANI-S study protocol: a non-randomised cluster controlled trial to assess the role of an unconditional cash transfer, a non-food item kit, and free piped water in reducing the risk of acute malnutrition among children aged 6-59 months living in cam (PubMed)

The REFANI-S study protocol: a non-randomised cluster controlled trial to assess the role of an unconditional cash transfer, a non-food item kit, and free piped water in reducing the risk of acute malnutrition among children aged 6-59 months living in cam The prevalence of acute malnutrition is often high in emergency-affected populations and is associated with elevated mortality risk and long-term health consequences. Increasingly, cash transfer programmes (CTP) are used instead of direct food

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2017 BMC Public Health

4. Complementary and Alternative Medicine (CAM) and Next-Generation CAM (NG-CAM) Strategies for Therapeutic Gut Microbiota Modulation in Inflammatory Bowel Disease (PubMed)

Complementary and Alternative Medicine (CAM) and Next-Generation CAM (NG-CAM) Strategies for Therapeutic Gut Microbiota Modulation in Inflammatory Bowel Disease The human gut microbiome exerts a major impact on human health and disease, and therapeutic gut microbiota modulation is now a well-advocated strategy in the management of many diseases, including inflammatory bowel disease (IBD). Scientific and clinical evidence in support of complementary and alternative medicine, in targeting

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2017 Gastroenterology clinics of North America

5. Complementary and alternative medicine (CAM) among Australian hospital-based nurses: knowledge, attitude, personal and professional use, reasons for use, CAM referrals, and socio-demographic predictors of CAM users. (PubMed)

Complementary and alternative medicine (CAM) among Australian hospital-based nurses: knowledge, attitude, personal and professional use, reasons for use, CAM referrals, and socio-demographic predictors of CAM users. This study was intended to examine CAM among Australian hospital-based nurses, identifying their knowledge, attitude, personal and professional use, reasons for use, CAM referrals, and socio-demographic predictors of CAM users.Nurses holding a qualification in nursing and working (...) in surgical wards were included using a convenience sampling technique. A self-complete questionnaire was developed to achieve the aims of the study. Descriptive and non-parametric statistics were calculated to describe and analyse data.Overall, 95.7% and 49.7% of nurses reported personal and professional use of CAM, respectively. The most popular CAM/CAM domain personally and professionally used by nurses was massage therapy and mind-body therapies. The primary reason for personal use of CAM

2017 Complementary Therapies in Clinical Practice

6. The I-CAM-FR: A French Translation and Cross-Cultural Adaptation of the I-CAM-Q (PubMed)

The I-CAM-FR: A French Translation and Cross-Cultural Adaptation of the I-CAM-Q Background: The use of complementary and alternative medicine (CAM) is growing every year. The extent of its use is still not clear, and it is difficult to undertake comparative studies due to the variety of data collection tools used. Therefore, a standardized International Complementary and Alternative Medicine Questionnaire (I-CAM-Q) has been recommended to determine data about its usage. The purpose (...) of the present study is to present a controlled translation of the questionnaire into French which is also properly adapted to a French audience. Methods: The English-written questionnaire, the I-CAM-Q, was submitted to three independent translators. Each translator produced a separate French translation (FT.1.1, FT.1.2, FT.1.3) that was then synthesized into a unique new version (FT.2.0). Version FT.2.0 was then submitted to three new translators, who translated them back to three distinct English versions

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2018 Medicines

7. CAMS Relational Agent System (CAMS-RAS) for Suicide Prevention

CAMS Relational Agent System (CAMS-RAS) for Suicide Prevention CAMS Relational Agent System (CAMS-RAS) for Suicide Prevention - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. CAMS Relational Agent System (...) (CAMS-RAS) for Suicide Prevention (V-CAMS) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03584386 Recruitment Status : Recruiting First Posted : July 12, 2018 Last Update Posted : February 26, 2019 See Sponsor: Evidence

2018 Clinical Trials

8. CAD-CAM Fabricated Zirconia Frameworks Provide Clinically Acceptable Fit at the Implant/Abutment Interface

) (Oral Surgery) (Prosthodontics) (Restorative Dentistry) Keywords Zirconia framework, titanium framework, all-on-four, implant supported fixed dental prosthesis (FDP), Computer aided design-computer aided manufacture, CAD/CAM, passive fit ID# 3291 Date of submission: 12/11/2017 E-mail deckert@livemail.uthscsa.edu Author Dr. Troy Decker, DDS Co-author(s) Dr. Melissa Thomas, DDS Co-author(s) e-mail thomasm@livemail.uthscsa.edu Faculty mentor/Co-author Faculty mentor/Co-author e-mail Basic Science (...) CAD-CAM Fabricated Zirconia Frameworks Provide Clinically Acceptable Fit at the Implant/Abutment Interface UTCAT3291, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title CAD-CAM Fabricated Zirconia Frameworks Provide Clinically Acceptable Fit at the Implant/Abutment Interface Clinical Question Does a zirconia framework fit as well as a titanium framework for an all-on-4 implant retained denture? Clinical Bottom Line CAD

2017 UTHSCSA Dental School CAT Library

9. Longevity of 3-Unit Bridge Restorations Utilizing CAD/CAM Technology Is Comparable to That of Metal-Ceramic Castings

efficiency and reduce the number of patient visits. These recommendations are due to the similar longevity seen in both processes. Specialty/Discipline (Prosthodontics) Keywords CAD-CAM, survival, fixed partial denture ID# 3157 Date of submission: 04/19/2017 E-mail Pirzadeh@livemail.uthscsa.edu Author Amir Pirzadeh Co-author(s) Co-author(s) e-mail Faculty mentor/Co-author Jeffery L. Hicks, BS, DDS Faculty mentor/Co-author e-mail hicksj@uthscsa.edu Basic Science Rationale (Mechanisms that may account (...) Longevity of 3-Unit Bridge Restorations Utilizing CAD/CAM Technology Is Comparable to That of Metal-Ceramic Castings UTCAT3157, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Longevity of 3-Unit Bridge Restorations Utilizing CAD/CAM Technology Is Comparable to That of Metal-Ceramic Castings Clinical Question In a patient needing a 3-unit bridge, does CAD/CAM technology lead to increased longevity as compared

2017 UTHSCSA Dental School CAT Library

10. Two?s Company, Three?s a Crowd: Dual versus triple therapy post-PCI

Two?s Company, Three?s a Crowd: Dual versus triple therapy post-PCI Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 5,000 family physicians, family medicine residents, and medical students in Alberta. Established over sixty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research. www.acfp.ca (...) . N Engl J Med. 2016; 375:2423-34. 4. Golwala HB, Cannon CP, Steg PG, et al. Eur Heart J. 2018; 39:1726-35. 5. Gong X, Tang S, Li J, et al. PLoS ONE. 2017; 12:e0186449. 6. Connolly SJ, Ezekowitz MD, Yusuf S, et al. NEJM. 2009; 361:1139-51. 7. Camm AJ, Accetta G, Ambrosio G, et al. Heart. 2017; 103:307-14. 8. Mehta SR, Bainey KR, Cantor WJ, et al. Can J Cardiol. 2018; 34:214-33. Tools for Practice is a biweekly article summarizing medical evidence with a focus on topical issues and practice

2019 Tools for Practice

11. CAM-S

CAM-S CAM-S Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 CAM-S CAM-S Aka: CAM-S , Confusion Assessment Method Short Form II (...) . Background Derived from original (CAM) Criteria were selected from those on the CAM that could be assessed objectively from the bedside III. Criteria: Grade each with score of 0-2 (based on above scale) Acute onset or symptom fluctuation Score 0: Absent Score 1: Present Inattention (e.g. list months backwards December to July, Indicate when examiner says an 'A' in S-A-V-E-A-H-A-A-R-T) Score 0: Absent Score 1: Mild Score 2: Marked Disorganized Thinking (e.g. Will a stone float? Fish in Sea? 1 lb > 2 lb

2018 FP Notebook

12. The CAM-S: Development and Validation of a New Scoring System for Delirium Severity in 2 Cohorts. (PubMed)

The CAM-S: Development and Validation of a New Scoring System for Delirium Severity in 2 Cohorts. Quantifying the severity of delirium is essential to advancing clinical care by improved understanding of delirium effect, prognosis, pathophysiology, and response to treatment.To develop and validate a new delirium severity measure (CAM-S) based on the Confusion Assessment Method.Validation analysis in 2 independent cohorts.Three academic medical centers.The first cohort included 300 patients aged (...) 70 years or older scheduled for major surgery. The second included 919 medical patients aged 70 years or older.A 4-item short form and a 10-item long form were developed. Association of the maximum CAM-S score during hospitalization with hospital and posthospital outcomes related to delirium was evaluated.Representative results included adjusted mean length of stay, which increased across levels of short-form severity from 6.5 days (95% CI, 6.2 to 6.9 days) to 12.7 days (CI, 11.2 to 14.3 days) (P

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2014 Annals of Internal Medicine

13. Anakinra (Kineret) - for the treatment of Still?s disease, including Systemic Juvenile Idiopathic Arthritis (SJIA) and Adult-Onset Still?s Disease (AOSD)

Anakinra (Kineret) - for the treatment of Still?s disease, including Systemic Juvenile Idiopathic Arthritis (SJIA) and Adult-Onset Still?s Disease (AOSD) Published 08 October 2018 1 SMC2104 anakinra 100mg/0.67mL solution for injection in pre- filled syringe (Kineret ® ) Swedish Orphan Biovitrum Ltd (SOBI) 7 September 2018 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use (...) effect of interleukin 1 inhibition with Kineret in adult-onset still's disease. An open, randomized, multicenter study. J Rheumatol. 2012;39(10):2008-11. 5. Ilowite N PA, Reiff S, Rudge M, Punaro A, et al. Anakinra in the treatment of polyarticular-course juvenile rheumatoid arthritis: Safety and preliminary efficacy results of a randomized multicenter study. Clin Rheumatol. 2009;28(2):129-37. 6. Hong D YZ, Han S, Liang X, Ma K, Zhang X,. Interleukin 1 inhibition with anakinra in adult-onset still

2018 Scottish Medicines Consortium

14. Rituximab (Blitzima) - follicular lymphoma and diffuse large B cell non-Hodgkin?s lymphoma OR chronic lymphocytic leukaemia OR granulomatosis with polyangiitis (GPA or Wegener?s granulomatosis) and microscopic polyangiitis (MPA)

Rituximab (Blitzima) - follicular lymphoma and diffuse large B cell non-Hodgkin?s lymphoma OR chronic lymphocytic leukaemia OR granulomatosis with polyangiitis (GPA or Wegener?s granulomatosis) and microscopic polyangiitis (MPA) 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact 18 May 2017 EMA/CHMP/421793/2017 Committee (...) aspects 12 2.1.1. Introduction 12 2.1.2. Active Substance 13 2.1.3. Finished Medicinal Product 16 2.1.4. Discussion on chemical, pharmaceutical and biological aspects 20 2.1.5. Conclusions on the chemical, pharmaceutical and biological aspects 20 2.1.6. Recommendation(s) for future quality development 20 2.2. Non-clinical aspects 20 2.2.1. Introduction 20 2.2.2. Pharmacology 21 2.2.3. Pharmacokinetics 26 2.2.4. Toxicology 27 2.2.5. Ecotoxicity/environmental risk assessment 29 2.2.6. Discussion on non

2017 European Medicines Agency - EPARs

15. Rituximab (Ritemvia) - follicular lymphoma and diffuse large B cell non-Hodgkin?s lymphoma OR granulomatosis with polyangiitis (GPA or Wegener?s granulomatosis) and microscopic polyangiitis (MPA)

Rituximab (Ritemvia) - follicular lymphoma and diffuse large B cell non-Hodgkin?s lymphoma OR granulomatosis with polyangiitis (GPA or Wegener?s granulomatosis) and microscopic polyangiitis (MPA) 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact 18 May 2017 EMA/CHMP/421799/2017 Committee for Medicinal Products for Human Use (CHMP (...) Substance 13 2.1.3. Finished Medicinal Product 16 2.1.4. Discussion on chemical, pharmaceutical and biological aspects 20 2.1.5. Conclusions on the chemical, pharmaceutical and biological aspects 20 2.1.6. Recommendation(s) for future quality development 20 2.2. Non-clinical aspects 20 2.2.1. Introduction 20 2.2.2. Pharmacology 21 2.2.3. Pharmacokinetics 26 2.2.4. Toxicology 27 2.2.5. Ecotoxicity/environmental risk assessment 29 2.2.6. Discussion on non-clinical aspects 30 2.2.7. Conclusion on the non

2017 European Medicines Agency - EPARs

16. Rituximab (Rituzena (previously Tuxella)) - follicular lymphoma and diffuse large B cell non-Hodgkin?s lymphoma OR chronic lymphocytic leukaemia OR granulomatosis with polyangiitis (GPA or Wegener?s granulomatosis) and microscopic polyangiitis (MPA)

Rituximab (Rituzena (previously Tuxella)) - follicular lymphoma and diffuse large B cell non-Hodgkin?s lymphoma OR chronic lymphocytic leukaemia OR granulomatosis with polyangiitis (GPA or Wegener?s granulomatosis) and microscopic polyangiitis (MPA) 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact 18 May 2017 EMA/CHMP/421811 (...) 10 2.1. Quality aspects 12 2.1.1. Introduction 12 2.1.2. Active Substance 13 2.1.3. Finished Medicinal Product 16 2.1.4. Discussion on chemical, pharmaceutical and biological aspects 20 2.1.5. Conclusions on the chemical, pharmaceutical and biological aspects 20 2.1.6. Recommendation(s) for future quality development 20 2.2. Non-clinical aspects 20 2.2.1. Introduction 20 2.2.2. Pharmacology 20 2.2.3. Pharmacokinetics 26 2.2.4. Toxicology 27 2.2.5. Ecotoxicity/environmental risk assessment 30

2017 European Medicines Agency - EPARs

17. Challenges When Translating and Culturally Adapting a Measurement Instrument: The Suitability and Comprehensibility of Materials (SAM+CAM) (PubMed)

Challenges When Translating and Culturally Adapting a Measurement Instrument: The Suitability and Comprehensibility of Materials (SAM+CAM) There is evidence that low suitability and comprehensibility of printed education materials (PEMs) affects patients' and relatives' ability to read and comprehend information. However, few instruments measure the suitability of written information, and none exist in the Swedish language. The aim was to describe the translation and adaptation (...) of the Suitability and Comprehensibility of Materials (SAM+CAM) instrument into the Swedish language and health care context and to explore challenges related to this process. The SAM+CAM instrument was translated and culturally adapted in five steps: forward translation, synthesis, back translation, expert review, and pretests. Differences were found when translating and culturally adapting the SAM+CAM instrument in the areas of semantic, idiomatic, and experiences. Participants revealed several clarity

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2018 Global qualitative nursing research

18. Impingement around the hip: beyond cam and pincer (PubMed)

Impingement around the hip: beyond cam and pincer In this review, we bring to the attention of the reader three relatively unknown types of hip impingement. We explain the concept of low anterior inferior iliac spine (AIIS) impingement, also known as sub-spine impingement, ischio-femoral impingement (IFI) and pelvi-trochanteric impingement. For each type of impingement, we performed a search of relevant literature.We searched the PubMed, Medline (Ovid) and Embase databases from 1960 to March

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2018 EFORT open reviews

19. CAD/CAM implant surgical guides: maximum errors in implant positioning attributable to the properties of the metal sleeve/osteotomy drill combination (PubMed)

CAD/CAM implant surgical guides: maximum errors in implant positioning attributable to the properties of the metal sleeve/osteotomy drill combination The purpose of this study is to provide the relevant equations and the reference tables needed for calculating the maximum errors in implant positioning attributed to the properties of the mechanical parts of any CAD/CAM implant surgical guide, especially the in-office manufactured ones.An algorithm was developed and implemented in C programming (...) of the implant axis 5.9° and the maximum error at the neck (entrance) of the implant was estimated 1.5 mm. The vertical error between the planned and actual implant position can be considered negligible (< 0.1 mm).The results of this study compute part of the expected differences in final clinical implant position when any CAD/CAM surgical guide is used. Given that the implantologist, with the capability of an in-office digital designed and 3d printed surgical guide, can readily decide upon the dimensions

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2018 International journal of implant dentistry

20. AMP-activated protein kinase–mediated feedback phosphorylation controls the Ca2+/calmodulin (CaM) dependence of Ca2+/CaM-dependent protein kinase kinase β (PubMed)

AMP-activated protein kinase–mediated feedback phosphorylation controls the Ca2+/calmodulin (CaM) dependence of Ca2+/CaM-dependent protein kinase kinase β The Ca2+/calmodulin-dependent protein kinase kinase β (CaMKKβ)/5'-AMP-activated protein kinase (AMPK) phosphorylation cascade affects various Ca2+-dependent metabolic pathways and cancer growth. Unlike recombinant CaMKKβ that exhibits higher basal activity (autonomous activity), activation of the CaMKKβ/AMPK signaling pathway requires (...) increased intracellular Ca2+ concentrations. Moreover, the Ca2+/CaM dependence of CaMKKβ appears to arise from multiple phosphorylation events, including autophosphorylation and activities furnished by other protein kinases. However, the effects of proximal downstream kinases on CaMKKβ activity have not yet been evaluated. Here, we demonstrate feedback phosphorylation of CaMKKβ at multiple residues by CaMKKβ-activated AMPK in addition to autophosphorylation in vitro, leading to reduced autonomous

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2017 The Journal of biological chemistry

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