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Breast MRI

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1. ACR–ASNR Practice Parameter for the Performance of Non-Breast Magnetic Resonance Imaging (MRI) Guided Procedures

ACR–ASNR Practice Parameter for the Performance of Non-Breast Magnetic Resonance Imaging (MRI) Guided Procedures PRACTICE PARAMETER MRI Guided / 1 The American College of Radiology, with more than 30,000 members, is the principal organization of radiologists, radiation oncologists, and clinical medical physicists in the United States. The College is a nonprofit professional society whose primary purposes are to advance the science of radiology, improve radiologic services to the patient, study (...) in each document. Reproduction or modification of the published practice parameter and technical standard by those entities not providing these services is not authorized. Revised 2013 (Resolution 8)* ACR–ASNR PRACTICE PARAMETER FOR THE PERFORMANCE OF NON- BREAST MAGNETIC RESONANCE IMAGING (MRI) GUIDED PROCEDURES PREAMBLE This document is an educational tool designed to assist practitioners in providing appropriate radiologic care for patients. Practice Parameters and Technical Standards

2019 American Society of Neuroradiology

2. The role of breast tomosynthesis in a predominantly dense breast population at a tertiary breast centre: breast density assessment and diagnostic performance in comparison with MRI (PubMed)

The role of breast tomosynthesis in a predominantly dense breast population at a tertiary breast centre: breast density assessment and diagnostic performance in comparison with MRI To compare breast density measured on digital breast tomosynthesis (DBT) (BI-RADS-based breast composition and fully-automatic estimation) and magnetic resonance imaging (MRI) (BI-RADS amount of fibroglandular tissue), and to evaluate the diagnostic performance in terms of sensitivity and specificity of DBT and MRI (...) in a predominantly dense breast population.Between 2015 and 2016, 152 women with 103 breast malignancies, who underwent 3-T breast MRI and DBT within 2 months' time, were enrolled in this study. Breast composition/fibroglandular tissue and findings on DBT (two readers) and MRI were reported using BI-RADS 5th edition. Digital mammography images were analysed for breast percent density (PD) using the Libra software tool.A majority of women had dense breasts as categorised by breast composition c (heterogeneously

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2018 European radiology

3. The correlation of background parenchymal enhancement in the contralateral breast with patient and tumor characteristics of MRI-screen detected breast cancers. (PubMed)

The correlation of background parenchymal enhancement in the contralateral breast with patient and tumor characteristics of MRI-screen detected breast cancers. Higher background parenchymal enhancement (BPE) could be used for stratification of MRI screening programs since it might be related to a higher breast cancer risk. Therefore, the purpose of this study is to correlate BPE to patient and tumor characteristics in women with unilateral MRI-screen detected breast cancer who participated (...) in an intermediate and high risk screening program. As BPE in the affected breast may be difficult to discern from enhancing cancer, we assumed that BPE in the contralateral breast is a representative measure for BPE in women with unilateral breast cancer.This retrospective study was approved by our local institutional board and a waiver for consent was granted. MR-examinations of women with unilateral breast cancers screen-detected on breast MRI were evaluated by two readers. BPE in the contralateral breast

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2018 PLoS ONE

4. Clinical value of delayed 18F-FDG PET/CT for predicting nipple-areolar complex involvement in breast cancer: A comparison with clinical symptoms and breast MRI. (PubMed)

Clinical value of delayed 18F-FDG PET/CT for predicting nipple-areolar complex involvement in breast cancer: A comparison with clinical symptoms and breast MRI. We aimed to evaluate the predictive value of delayed 18F-FDG PET/CT for identifying malignancies involved in the nipple-areolar complex (NAC) in comparison with clinical symptoms and breast MRI.We enrolled 90 patients who underwent preoperative delayed 18F-FDG PET/CT and MRI between October 2015 and May 2017. We calculated the NAC (...) -Standardized uptake value ratio (SUVR) using the following formula: maximum SUV (SUVmax) of the NAC in the malignant breast /SUVmax of the NAC in the contralateral normal breast on early (NAC-SUVRearly) and delayed (NAC-SUVRdelay) phase images. MRI was used to measure the distance between the tumor and NAC and to analyze NAC enhancement patterns. Univariate and multivariate analyses were performed to identify significant predictive factors for NAC involvement.Seventeen patients were confirmed to have

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2018 PLoS ONE

5. Performance of Screening Breast MRI across Women with Different Elevated Breast Cancer Risk Indications. (PubMed)

Performance of Screening Breast MRI across Women with Different Elevated Breast Cancer Risk Indications. Background Screening breast MRI is recommended for women with BRCA mutation or a history of chest radiation, but guidelines are equivocal for MRI screening of women with a personal history of breast cancer or high-risk lesion. Purpose To evaluate screening breast MRI performance across women with different elevated breast cancer risk indications. Materials and Methods All screening breast (...) MRI examinations performed between 2011 and 2014 underwent retrospective medical record review. Indications for screening were as follows: BRCA mutation carrier or history of chest radiation (BRCA/RT group), family history of breast cancer (FH group), personal history of breast cancer (PH group), and history of high-risk lesion (HRL group). Screening performance metrics were calculated and compared among indications by using logistic regression adjusted for age, available prior MRI, mammographic

2019 Radiology

6. MRI and Prediction of Pathologic Complete Response in the Breast and Axilla after Neoadjuvant Chemotherapy for Breast Cancer: MRI and Pathologic Complete Response. (PubMed)

MRI and Prediction of Pathologic Complete Response in the Breast and Axilla after Neoadjuvant Chemotherapy for Breast Cancer: MRI and Pathologic Complete Response. In the setting where determining extent of residual disease is key for surgical planning after neoadjuvant chemotherapy (NAC), we evaluate the reliability of MRI in predicting pathologic complete response (pCR) of the breast primary and axillary nodes after NAC.Patients who had MRI before and after NAC between June 2014 and August (...) 2015 were identified in a prospective database after IRB approval. Post-NAC MRI of the breast and axillary nodes was correlated with residual disease on final pathology. Pathologic complete response was defined as absence of invasive and in situ disease.We analyzed 129 breast cancers. Median patient age was 50.8 years (range 27.2 to 80.6 years). Tumors were human epidermal growth factor receptor 2 amplified in 52 of 129 (40%), estrogen receptor-positive/human epidermal growth factor receptor 2

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2017 Journal of the American College of Surgeons

7. Magnetic resonance imaging (MRI) for surveillance for breast cancer recurrence following mastectomy and breast reconstruction

Magnetic resonance imaging (MRI) for surveillance for breast cancer recurrence following mastectomy and breast reconstruction Magnetic resonance imaging (MRI) for surveillance for breast cancer recurrence following mastectomy and breast reconstruction Magnetic resonance imaging (MRI) for surveillance for breast cancer recurrence following mastectomy and breast reconstruction Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality (...) of this assessment has been made for the HTA database. Citation Magnetic resonance imaging (MRI) for surveillance for breast cancer recurrence following mastectomy and breast reconstruction. Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2014 Authors' conclusions In the United States, an estimated 235,030 new cases of invasive breast cancer will be diagnosed in 2014, and an estimated 40,430 patients will die of the disease. Given a choice of breast-conserving surgery plus adjunct radiotherapy

2014 Health Technology Assessment (HTA) Database.

8. Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis (PubMed)

Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis Radiomics is an emerging technology for imaging biomarker discovery and disease-specific personalized treatment management. This paper aims to determine the benefit of using multi-modality radiomics data from PET and MR images in the characterization breast cancer phenotype and prognosis. Eighty-four features were extracted from PET and MR images of 113 breast cancer patients. Unsupervised (...) clustering based on PET and MRI radiomic features created three subgroups. These derived subgroups were statistically significantly associated with tumor grade (p = 2.0 × 10-6), tumor overall stage (p = 0.037), breast cancer subtypes (p = 0.0085), and disease recurrence status (p = 0.0053). The PET-derived first-order statistics and gray level co-occurrence matrix (GLCM) textural features were discriminative of breast cancer tumor grade, which was confirmed by the results of L2-regularization logistic

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2018 NPJ breast cancer

9. TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer

TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer (TMEM-MRI) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03694756

2018 Clinical Trials

10. Integrated radiomic framework for breast cancer and tumor biology using advanced machine learning and multiparametric MRI (PubMed)

Integrated radiomic framework for breast cancer and tumor biology using advanced machine learning and multiparametric MRI Radiomics deals with the high throughput extraction of quantitative textural information from radiological images that not visually perceivable by radiologists. However, the biological correlation between radiomic features and different tissues of interest has not been established. To that end, we present the radiomic feature mapping framework to generate radiomic MRI (...) texture image representations called the radiomic feature maps (RFM) and correlate the RFMs with quantitative texture values, breast tissue biology using quantitative MRI and classify benign from malignant tumors. We tested our radiomic feature mapping framework on a retrospective cohort of 124 patients (26 benign and 98 malignant) who underwent multiparametric breast MR imaging at 3 T. The MRI parameters used were T1-weighted imaging, T2-weighted imaging, dynamic contrast enhanced MRI (DCE-MRI

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2017 NPJ breast cancer

11. Concurrent versus Sequential Digital Mammography and MRI for Breast Cancer Screening in High-Risk Patients

Concurrent versus Sequential Digital Mammography and MRI for Breast Cancer Screening in High-Risk Patients Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed (...) Sequential Digital Mammography and MRI for Breast Cancer Screening in High-Risk Patients: Comparative Clinical Effectiveness, Cost- Effectiveness, and Guidelines DATE: 06 May 2015 RESEARCH QUESTIONS 1. What is the comparative clinical effectiveness of concurrent versus sequential digital mammography and magnetic resonance imaging (MRI) for breast cancer screening in high-risk patients? 2. What is the comparative cost-effectiveness of concurrent versus sequential digital mammography and MRI for breast

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

12. Breast Magnetic Resonance Imaging (MRI)

Breast Magnetic Resonance Imaging (MRI) A Applic Date o Context at www 1. An appl treatme of Aust Septem 2. After co and cos plannin ? ? ? ? ? ? MSAC effectiv After co and cos ? Applicatio cant: of MSAC c t for decisio w.msac.gov. Purpose o lication req ent in wome tralia and N mber 2012. MSAC’s a onsidering t st-effectiven ng of newly undergoing with lobula aged 50 yea with very d who have s who have s ductal carci did not sup veness, cost- onsidering t st-effectiven local stagin with metast (...) examinatio Pub on No. 13 onsiderat on: MSAC m au of applica questing Me en newly dia ew Zealand advice to t the availabl ness of MRI diagnosed b g neo-adjuva ar subtype b ars or young dense breast significant s suspicious/m inoma in sit pport public -effectivene the availabl ness of MRI ng and/or ea tatic breast n fails to sh lic Sum 333 – Bre Pro Bre ion: MS makes its ad tion and l dicare Bene agnosed wit d Incorporat the Ministe e evidence p I for local st breast cance ant chemoth breast cancer ger, ts

2015 Medical Services Advisory Committee

13. MRI features predictive of negative surgical margins in patients with HER2 overexpressing breast cancer undergoing breast conservation (PubMed)

MRI features predictive of negative surgical margins in patients with HER2 overexpressing breast cancer undergoing breast conservation Here we develop a tool to predict resectability of HER2+ breast cancer at breast conservation surgery (BCS) utilizing features identified on preoperative breast MRI. We identified patients with HER2+ breast cancer who obtained pre-operative breast MRI and underwent BCS between 2002-2013. From the contoured tumor on pre-operative MRI, shape, histogram, and co (...) -occurrence and size zone matrix texture features were extracted. In univariate analysis, Spearman's correlation coefficient (Rs) was used to assess the correlation between each image feature and an endpoint (surgical re-excision). For multivariate modeling, we employed a support vector machine (SVM) method in a manner of leave-one-out cross-validation (LOOCV). Of 109 patients with HER2+breast cancer who underwent BCS, 39% underwent surgical re-excision. 62% had residual cancer at re-excision

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2018 Scientific reports

14. Abbreviated Breast MRI for Second Breast Cancer Detection in Women With BRCA Mutation Testing

Abbreviated Breast MRI for Second Breast Cancer Detection in Women With BRCA Mutation Testing Abbreviated Breast MRI for Second Breast Cancer Detection in Women With BRCA Mutation Testing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Abbreviated Breast MRI for Second Breast Cancer Detection in Women With BRCA Mutation Testing The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03475979 Recruitment Status : Recruiting

2018 Clinical Trials

15. Comparing Restriction Spectrum Imaging (RSI) to Conventional and Abbreviated Breast MRI for Breast Cancer Screening

Comparing Restriction Spectrum Imaging (RSI) to Conventional and Abbreviated Breast MRI for Breast Cancer Screening Comparing Restriction Spectrum Imaging (RSI) to Conventional and Abbreviated Breast MRI for Breast Cancer Screening - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Comparing Restriction Spectrum Imaging (RSI) to Conventional and Abbreviated Breast MRI for Breast Cancer Screening The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2018 Clinical Trials

16. Dedicated Breast PET/MRI in Evaluation of Extent of Disease in Women With Newly Diagnosed Breast Cancer

Dedicated Breast PET/MRI in Evaluation of Extent of Disease in Women With Newly Diagnosed Breast Cancer Dedicated Breast PET/MRI in Evaluation of Extent of Disease in Women With Newly Diagnosed Breast Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Dedicated Breast PET/MRI in Evaluation of Extent of Disease in Women With Newly Diagnosed Breast Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03510988

2018 Clinical Trials

17. Breast MRI for Neaodjuvant Chemotherapy Response Prediction and Evaluation in Breast Cancer

Breast MRI for Neaodjuvant Chemotherapy Response Prediction and Evaluation in Breast Cancer Breast MRI for Neaodjuvant Chemotherapy Response Prediction and Evaluation in Breast Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Breast MRI for Neaodjuvant Chemotherapy Response Prediction and Evaluation in Breast Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03580837 Recruitment Status : Recruiting First Posted

2018 Clinical Trials

18. Feasibility Study of Supine Breast MRI : Comparison With Prone MRI and Comfort Assessment

Feasibility Study of Supine Breast MRI : Comparison With Prone MRI and Comfort Assessment Feasibility Study of Supine Breast MRI : Comparison With Prone MRI and Comfort Assessment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Feasibility Study of Supine Breast MRI : Comparison With Prone MRI and Comfort Assessment The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03088436 Recruitment Status : Completed First Posted : March 23, 2017 Last Update Posted : March 23, 2017 Sponsor: Institut de

2017 Clinical Trials

19. A simple classification system (the Tree flowchart) for breast MRI can reduce the number of unnecessary biopsies in MRI-only lesions (PubMed)

A simple classification system (the Tree flowchart) for breast MRI can reduce the number of unnecessary biopsies in MRI-only lesions To assess whether using the Tree flowchart obviates unnecessary magnetic resonance imaging (MRI)-guided biopsies in breast lesions only visible on MRI.This retrospective IRB-approved study evaluated consecutive suspicious (BI-RADS 4) breast lesions only visible on MRI that were referred to our institution for MRI-guided biopsy. All lesions were evaluated according (...) to the Tree flowchart for breast MRI by experienced readers. The Tree flowchart is a decision rule that assigns levels of suspicion to specific combinations of diagnostic criteria. Receiver operating characteristic (ROC) curve analysis was used to evaluate diagnostic accuracy. To assess reproducibility by kappa statistics, a second reader rated a subset of 82 patients.There were 454 patients with 469 histopathologically verified lesions included (98 malignant, 371 benign lesions). The area under the curve

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2017 European radiology

20. Utility of Diffusion Weighted Imaging to Decrease Unnecessary Biopsies Prompted by Breast MRI: A Trial of the ECOG-ACRIN Cancer Research Group (A6702). (PubMed)

Utility of Diffusion Weighted Imaging to Decrease Unnecessary Biopsies Prompted by Breast MRI: A Trial of the ECOG-ACRIN Cancer Research Group (A6702). Conventional breast MRI is highly sensitive for cancer detection but prompts some false positives. We performed a prospective, multicenter study to determine whether apparent diffusion coefficients (ADCs) from diffusion-weighted imaging (DWI) can decrease MRI false positives.Experimental Design: A total of 107 women with MRI-detected BI-RADS 3 (...) , 11.2%-31.2%) without affecting sensitivity. Application of a more conservative threshold (1.68 × 10-3 mm2/s) to site-measured ADCs reduced the biopsy rate by 26.2% (16/61) but missed three cancers.DWI can reclassify a substantial fraction of suspicious breast MRI findings as benign and thereby decrease unnecessary biopsies. ADC thresholds identified in this trial should be validated in future phase III studies.©2019 American Association for Cancer Research.

2019 Clinical Cancer Research

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