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Body Mass Index

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181. Interaction analysis of gene variants of TCF7L2 and body mass index and waist circumference on type 2 diabetes. (PubMed)

Interaction analysis of gene variants of TCF7L2 and body mass index and waist circumference on type 2 diabetes. Type 2 diabetes (T2D) is a complex metabolic disease with numerous risk factors, including a growing number of genetic susceptibility variants. The TCF7L2 gene is closely associated with an increased risk of type 2 diabetes, but the association of TCF7L2 with weight-related traits in humans is unclear. The purpose of this study was to determine if TCF7L2 variants and body mass index (...) (synergy index) was 1.822 (95%CI: 1.463-2.268). Additionally, there was a significant interaction between rs 290487 and abdominal obesity on the risk of T2D (RERI: 2.642, 95%CI: 1.384-3.900; AP: 0.350, 95%CI: 0.231-0.468; SI: 1.675, 95%CI: 1.348-2.083).These results show that a TCF7L2 gene-BMI interaction or gene-WC interaction may play an important role in the risk for T2D in the Chinese population.Copyright © 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights

2019 Clinical nutrition (Edinburgh, Scotland)

182. Body mass index in early pregnancy and future risk of severe liver disease: a population-based cohort study. (PubMed)

Body mass index in early pregnancy and future risk of severe liver disease: a population-based cohort study. In young men, high body mass index (BMI) has been linked to liver disease later in life, but it is unclear if this also applies to women.To study the association between BMI early in life and development of liver disease later in life in women.We obtained data on early pregnancy BMI from 1 139 458 Swedish women between 1992 and 2015. National registers were used to ascertain incident

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2019 Alimentary Pharmacology & Therapeutics

183. Body Mass Index Variability and Long-term Risk of New-Onset Atrial Fibrillation in the General Population: A Korean Nationwide Cohort Study. (PubMed)

Body Mass Index Variability and Long-term Risk of New-Onset Atrial Fibrillation in the General Population: A Korean Nationwide Cohort Study. To assess the effects of body mass index (BMI) variability on the incidence of new-onset atrial fibrillation (AF), stroke, cardiovascular (CV) risk factors, and CV outcomes in a general Asian population.Data from the National Health Insurance Service-Health Screening cohort in Korea were used: 171,324 patients without AF were included, and BMI measurements

2019 Mayo Clinic Proceedings

184. Effect of Patient Body Mass Index on Laparoscopic Surgical Ergonomics. (PubMed)

Effect of Patient Body Mass Index on Laparoscopic Surgical Ergonomics. Minimally invasive surgery may introduce new ergonomic challenges for surgeons. Increased patient body mass index (BMI) may further add to this ergonomic stress.The objective of this study was to quantify the ergonomic impact of patient BMI on surgeons during laparoscopic surgery.University Hospital, USA.This prospective cohort study analyzed five minimally invasive surgeons during 24 laparoscopic procedures. Each subject's (...) muscle stress was assessed by recording surface electromyography (EMG) data from eight upper body muscle groups during laparoscopic procedures. EMG data was normalized against the maximal voluntary contraction (MVC) of each muscle measured before the start of surgery to create a percentage of the MVC value (%MVC). Subject workload was assessed through the NASA Task Load Index (NTLX). Statistical analysis was used to determine significance between surgeons operating on patients with or without obesity

2019 Obesity Surgery

185. Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. (PubMed)

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. Psoriasis is a common inflammatory skin disease that has been reported to be associated with obesity. We aimed to investigate a possible causal relationship between body mass index (BMI) and psoriasis.Following a review of published epidemiological evidence of the association between obesity and psoriasis, mendelian randomization (MR) was used to test for a causal relationship with BMI. We

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2019 PLoS medicine

186. Pharmacokinetics of the 1.5mg levonorgestrel emergency contraceptive in women with normal, obese and extremely obese body mass index. (PubMed)

Pharmacokinetics of the 1.5mg levonorgestrel emergency contraceptive in women with normal, obese and extremely obese body mass index. To assess the pharmacokinetics (PK) of levonorgestrel after 1.5 mg oral doses (LNG-EC) in women with normal, obese and extremely obese body mass index (BMI).The 1.5 mg LNG dose was given to healthy, reproductive-age, ovulatory women with normal BMI (mean 22.0), obese (mean 34.4), and extremely obese (mean 46.6 kg/m2) BMI. Total serum LNG was measured over 0 to 96

2019 Contraception

187. The relationship between body mass index and oral health status among Saudi adults: a cross-sectional study. (PubMed)

The relationship between body mass index and oral health status among Saudi adults: a cross-sectional study. To assess the relationship between body mass index (BMI) and the sum of decayed, missing and filled teeth (DMFT), periodontal pockets, and oral soft tissue variations.A systematic sample of 250 people attending King Abdulaziz Medical City was included. The study was conducted using questionnaires and clinical examinations. Questionnaires were prepared to include socio-demographic

2019 Community dental health

188. Body mass index and physical fitness among Chinese adolescents from Shandong Province: a cross-sectional study. (PubMed)

Body mass index and physical fitness among Chinese adolescents from Shandong Province: a cross-sectional study. This study aimed to describe the most recent prevalence estimates of adolescent body mass index (BMI) and physical fitness from thirteen regions in Shandong Province, China and to examine differences by social-economic status (SES).The participants were 27,955 adolescents (mean age = 14.4 ± 1.8 years; 13,791 girls) enrolled from 91 public middle and high schools randomly selected from

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2019 BMC Public Health

189. Association between body mass index and surgical menopausal symptoms in patients with early stage endometrial cancer. (PubMed)

Association between body mass index and surgical menopausal symptoms in patients with early stage endometrial cancer. Premenopausal women may undergo surgical menopause after staging for their endometrial cancer. Our aim was to determine the association between body mass index (BMI) and surgical menopausal symptoms.We report a retrospective review of endometrial cancer patients whom underwent menopause secondary to their surgical staging procedure. Symptoms were classified as severe

2019 Gynecologic Oncology

190. Long-Term Burden of Higher Body Mass Index and Adult Arterial Stiffness Are Linked Predominantly Through Elevated Blood Pressure. (PubMed)

Long-Term Burden of Higher Body Mass Index and Adult Arterial Stiffness Are Linked Predominantly Through Elevated Blood Pressure. Obesity and hypertension are important risk factors of arterial stiffness. However, the complex relationship between increased body mass index (BMI), elevated blood pressure (BP), and arterial stiffness is largely unknown. We aim to examine the mediation effect of elevated BP on the association of early life BMI, long-term burden, and trend of BMI with arterial

2019 Hypertension

191. Socioeconomic differences in body mass index in Spain: An intersectional multilevel analysis of individual heterogeneity and discriminatory accuracy. (PubMed)

Socioeconomic differences in body mass index in Spain: An intersectional multilevel analysis of individual heterogeneity and discriminatory accuracy. Many studies have demonstrated the existence of simple, unidimensional socioeconomic gradients in body mass index (BMI). However, in the present paper we move beyond such traditional analyses by simultaneously considering multiple demographic and socioeconomic dimensions. Using the Spanish National Health Survey 2011-2012, we apply

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2018 PLoS ONE

192. Age at menarche and childhood body mass index as predictors of cardio-metabolic risk in young adulthood: A prospective cohort study. (PubMed)

Age at menarche and childhood body mass index as predictors of cardio-metabolic risk in young adulthood: A prospective cohort study. This study aimed to examine the association between age at menarche and a range of cardiovascular disease (CVD) risk factors at 17 and 20 years of age, and whether this was influenced by childhood body mass index (BMI).Of the 1413 girls born in the Western Australian Pregnancy Cohort (Raine) Study, 846 had age at menarche recorded. Subsequently 557 underwent

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2018 PLoS ONE

193. Friendship as a social mechanism influencing body mass index (BMI) among emerging adults. (PubMed)

Friendship as a social mechanism influencing body mass index (BMI) among emerging adults. Social relationships have been proposed as a significant factor shaping obesity risk. The first year of college, a period of major social, behavioral, and weight changes, provides a context well-suited to tracking longitudinally the impact of shifting friendships on weight outcomes. This study sought to identify social mechanisms impacting BMI change among emerging adults.An analytic sample of 276 college

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2018 PLoS ONE

194. Relationship of body mass index and waist circumference with clinical outcomes following percutaneous coronary intervention. (PubMed)

Relationship of body mass index and waist circumference with clinical outcomes following percutaneous coronary intervention. A biphasic, U-shape relationship has been reported between body mass index (BMI) and clinical outcomes following percutaneous coronary intervention (PCI). However, the relationship between waist circumference (WC) and the cardiovascular risk following PCI has not been reported.A prospective cohort study was performed. A major adverse cardiac event (MACE) was defined

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2018 PLoS ONE

195. Physical exercise and body mass index as correlates of major depressive disorder in community-dwelling adults: Results from the PISMA-ep study. (PubMed)

Physical exercise and body mass index as correlates of major depressive disorder in community-dwelling adults: Results from the PISMA-ep study. Major Depressive Disorder (MDD) is one of the most prevalent and disabling mental disorders. Sedentarism and obesity are recognized risk factors for MDD. Physical exercise has shown beneficial effects on mental health and there is an increasing awareness of its potential as a therapeutic and preventive tool for depression. No epidemiological studies (...) ). Independent variables explored were physical exercise and its intensity, Body Mass Index (BMI), BMI categories (underweight, normal weight, overweight and obesity), hip and waist circumferences, general health status measured with the SF12 questionnaire, and sociodemographic factors.Physical exercise was inversely associated with MDD, acting as a protective factor. Higher intensity of exercise strengthened this association. Four variables were independently associated with MDD in the multivariate

2019 Journal of Affective Disorders

196. Body mass index and mortality in individuals with type 1 diabetes. (PubMed)

Body mass index and mortality in individuals with type 1 diabetes. The relationship between BMI and mortality in type 1 diabetes might differ from the general population and it is not known which clinical characteristics modify the relationship.Our aim was to assess the relationship between BMI and mortality and the interaction with clinically meaningful factors.This prospective study included 5,836 individuals with type 1 diabetes from the FinnDiane study.. We retrieved death data for all

2019 Journal of Clinical Endocrinology and Metabolism

197. The role of body mass index in determining clinical and quality of life outcomes after laparoscopic anti-reflux surgery. (PubMed)

The role of body mass index in determining clinical and quality of life outcomes after laparoscopic anti-reflux surgery. Current literature is conflicted regarding the efficacy of laparoscopic anti-reflux surgery (LARS) among obese patients complaining of pathologic reflux or otherwise symptomatic hiatal hernias. Controlling for other factors, this study examined the influence of preoperative body mass index (BMI) on clinical and subjective quality of life (QOL) outcomes following LARS.Patients (...) who underwent LARS between February 2012 and April 2018 were subdivided into four BMI stratified categories according to CDC definitions: normal (18.5 to < 25), overweight (25.0 to < 30), obese Class 1 (30 to < 35), and a combination of obese Class 2 (35 to < 40) and Class 3 (≥ 40). Patient demography, perioperative data, and QOL data were collected. QOL was assessed utilizing four validated survey instruments: the Reflux Symptom Index (RSI), Gastroesophageal Reflux Disease Health-Related Quality

2019 Surgical endoscopy

198. Body mass index is associated with risk of reoperation and revision after primary total hip arthroplasty: a study of the Swedish Hip Arthroplasty Register including 83,146 patients. (PubMed)

Body mass index is associated with risk of reoperation and revision after primary total hip arthroplasty: a study of the Swedish Hip Arthroplasty Register including 83,146 patients. Background and purpose - The prevalence of obesity is on the rise, becoming a worldwide epidemic. The main purpose of this register-based observational study was to investigate whether different BMI classes are associated with increased risk of reoperation within 2 years, risk of revision within 5 years

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2019 Acta Orthopaedica

199. Body mass index trajectories in pediatric multiple sclerosis. (PubMed)

Body mass index trajectories in pediatric multiple sclerosis. To characterize growth trajectories of children who develop multiple sclerosis compared to typically developing, regional peers and Centers for Disease Control (CDC) normative values.This case-control study collected weight, height, and body mass index (BMI) in 40 consecutive pediatric patients with multiple sclerosis (28 females, 12 males), in addition to 120 typically developing peers (84 females, 36 males), identified and matched (...) differences in BMI are noted from 4 years of age and onward. Height trajectories were similar among case and control individuals and CDC normative values.BMI in pediatric multiple sclerosis is markedly higher, beginning in early childhood, years before the clinical-onset of the disease.Children with multiple sclerosis are significantly more overweight than typically developing peers at the time of diagnosis. Body mass index trajectories are significantly higher years before the clinical manifestation(s

2019 Developmental Medicine and Child Neurology

200. The Effect of Bariatric Surgery on Asian Patients with Type 2 Diabetes Mellitus and Body Mass Index &lt; 30 kg/m<sup>2</sup>: a Systematic Review and Meta-analysis. (PubMed)

The Effect of Bariatric Surgery on Asian Patients with Type 2 Diabetes Mellitus and Body Mass Index < 30 kg/m2: a Systematic Review and Meta-analysis. The effect of bariatric surgery on the glycemic control of patients with obesity and type 2 diabetes mellitus is obvious. However, the effect in patients with body mass index (BMI) < 30 kg/m2 especially Asian population has not been widely reported and acknowledged.We performed a literature search in Medline, Embase (...) , and the Cochrane Library from January 2000 to March 2018. All the studies involving the effect of bariatric surgery on patients with type 2 diabetes and BMI < 30 kg/m2 from Asian countries or regions were included in this meta-analysis.Twelve studies including 697 patients were examined in this meta-analysis. Clinical indexes in 6, 12, and 24 months follow-up were analyzed, respectively. BMI and waist circumference reduced by 2.88 kg/m2 and 12.92 cm, respectively, at 12 months postoperatively. There were

2019 Obesity Surgery

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