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Blood Lactic Acid

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81. Studies on the lactic acid, sugar and inorganic phosphorus of the blood of ruminants Full Text available with Trip Pro

Studies on the lactic acid, sugar and inorganic phosphorus of the blood of ruminants 16745126 2006 06 05 2018 11 13 0264-6021 27 2 1933 The Biochemical journal Biochem. J. Studies on the lactic acid, sugar and inorganic phosphorus of the blood of ruminants. 512-22 Allcroft W M WM The Rowett Research Institute, Aberdeen. Strand R R eng Journal Article England Biochem J 2984726R 0264-6021 1933 1 1 0 0 1933 1 1 0 1 1933 1 1 0 0 ppublish 16745126 PMC1252908 J Clin Invest. 1928 Oct;6(2):303-17

1933 Biochemical Journal

82. Utilization of blood sugar and formation of lactic acid by the lungs Full Text available with Trip Pro

Utilization of blood sugar and formation of lactic acid by the lungs 16994566 2007 02 05 2018 11 13 0022-3751 82 1 1934 Aug 24 The Journal of physiology J. Physiol. (Lond.) Utilization of blood sugar and formation of lactic acid by the lungs. 41-61 Evans C L CL Hsu F Y FY Kosaka T T eng Journal Article England J Physiol 0266262 0022-3751 1934 8 24 0 0 1934 8 24 0 1 1934 8 24 0 0 ppublish 16994566 PMC1394641 Biochem J. 1926;20(3):613-9 16743700 Biochem J. 1931;25(1):339-41 16744584 J Physiol

1934 The Journal of physiology

83. The lactic acid content of the blood after muscular contraction under experimental conditions Full Text available with Trip Pro

The lactic acid content of the blood after muscular contraction under experimental conditions 16994142 2007 02 05 2018 11 13 0022-3751 70 3 1930 Oct 31 The Journal of physiology J. Physiol. (Lond.) The lactic acid content of the blood after muscular contraction under experimental conditions. 269-93 Eggleton M G MG Evans C L CL eng Journal Article England J Physiol 0266262 0022-3751 1930 10 31 0 0 1930 10 31 0 1 1930 10 31 0 0 ppublish 16994142 PMC1402986 Biochem J. 1930;24(1):67-76 16744354 J

1930 The Journal of physiology

84. Lactic acid formation and removal with change of blood reaction Full Text available with Trip Pro

Lactic acid formation and removal with change of blood reaction 16994141 2007 02 05 2018 11 13 0022-3751 70 3 1930 Oct 31 The Journal of physiology J. Physiol. (Lond.) Lactic acid formation and removal with change of blood reaction. 261-8 Eggleton M G MG Evans C L CL eng Journal Article England J Physiol 0266262 0022-3751 1930 10 31 0 0 1930 10 31 0 1 1930 10 31 0 0 ppublish 16994141 PMC1402988 J Physiol. 1923 Dec 28;58(2-3):244-58 16993658 J Physiol. 1928 Feb 10;64(4):356-64 16993927 J Physiol

1930 The Journal of physiology

85. LACTIC ACID IN THE BLOOD OF RESTING MAN Full Text available with Trip Pro

LACTIC ACID IN THE BLOOD OF RESTING MAN 16694077 2006 05 31 2018 11 13 0021-9738 11 4 1932 Jul The Journal of clinical investigation J. Clin. Invest. LACTIC ACID IN THE BLOOD OF RESTING MAN. 775-88 Bock A V AV Fatigue Laboratory, Morgan Hall, Harvard University, Boston. Dill D B DB Edwards H T HT eng Journal Article United States J Clin Invest 7802877 0021-9738 1932 7 1 0 0 1932 7 1 0 1 1932 7 1 0 0 ppublish 16694077 10.1172/JCI100450 PMC435852 J Clin Invest. 1927 Jun;4(2):273-93 16693758 J

1932 Journal of Clinical Investigation

86. Blood lactic acid in man during rest Full Text available with Trip Pro

Blood lactic acid in man during rest 16994471 2007 02 05 2018 11 13 0022-3751 79 4 1933 Oct 25 The Journal of physiology J. Physiol. (Lond.) Blood lactic acid in man during rest. 443-54 Cook L C LC Hurst R H RH eng Journal Article England J Physiol 0266262 0022-3751 1933 10 25 0 0 1933 10 25 0 1 1933 10 25 0 0 ppublish 16994471 PMC1394849 Biochem J. 1932;26(2):381-7 16744835 Biochem J. 1932;26(5):1536-41 16744974 J Physiol. 1907 Mar 27;35(4):247-309 16992858 J Physiol. 1920 Dec 7;54(4):292-318

1933 The Journal of physiology

87. THE LACTIC ACID AND GLUTATHIONE CONTENT OF THE BLOOD OF SCHIZOPHRENIC PATIENTS Full Text available with Trip Pro

THE LACTIC ACID AND GLUTATHIONE CONTENT OF THE BLOOD OF SCHIZOPHRENIC PATIENTS 16694262 2006 05 31 2008 11 20 0021-9738 13 6 1934 Nov The Journal of clinical investigation J. Clin. Invest. THE LACTIC ACID AND GLUTATHIONE CONTENT OF THE BLOOD OF SCHIZOPHRENIC PATIENTS. 963-8 Looney J M JM Memorial Foundation for Neuro-Endocrine Research, Worcester. Childs H M HM eng Journal Article United States J Clin Invest 7802877 0021-9738 1934 11 1 0 0 1934 11 1 0 1 1934 11 1 0 0 ppublish 16694262 10.1172

1934 Journal of Clinical Investigation

88. Adrenaline and the blood lactic acid level in hypophysectomized rabbits Full Text available with Trip Pro

Adrenaline and the blood lactic acid level in hypophysectomized rabbits 16994834 2007 02 05 2018 11 13 0022-3751 88 4 1937 Jan 18 The Journal of physiology J. Physiol. (Lond.) Adrenaline and the blood lactic acid level in hypophysectomized rabbits. 417-24 Cope O O Thompson R H RH eng Journal Article England J Physiol 0266262 0022-3751 1937 1 18 0 0 1937 1 18 0 1 1937 1 18 0 0 ppublish 16994834 PMC1395192 J Physiol. 1933 Nov 9;80(1):21-40 16994482 J Physiol. 1933 Dec 5;80(2):193-205 16994494 J

1937 The Journal of physiology

89. Further studies on the lactic acid, sugar and inorganic phosphorus of the blood of ruminants, (a) following adrenalectomy and (b) after intravenous injection of insulin Full Text available with Trip Pro

Further studies on the lactic acid, sugar and inorganic phosphorus of the blood of ruminants, (a) following adrenalectomy and (b) after intravenous injection of insulin 16745428 2006 06 05 2018 11 13 0264-6021 28 2 1934 The Biochemical journal Biochem. J. Further studies on the lactic acid, sugar and inorganic phosphorus of the blood of ruminants, (a) following adrenalectomy and (b) after intravenous injection of insulin. 642-9 Strand R R The Rowett Research Institute, Aberdeen. Anderson W W

1934 Biochemical Journal

90. A Quantitative Analysis of the Genetics of Resting Blood Lactic Acid Levels in Mice Full Text available with Trip Pro

A Quantitative Analysis of the Genetics of Resting Blood Lactic Acid Levels in Mice Resting blood lactate levels were measured in inbred mouse strains, their F(1), and several of their segregating generations to determine whether the level of lactic acid is influenced by genetic factors. The inbred strains in each of the two sets used differed significantly from one another for this character. Only one strain showed a significant sex difference. The data could not be fully analyzed because

1973 Genetics

91. Automated enzymatic fluorometric method for the determination of pyruvic and lactic acids in blood Full Text available with Trip Pro

Automated enzymatic fluorometric method for the determination of pyruvic and lactic acids in blood A simple automated fluorometric method for the estimation of lactate and pyruvate is described. Analyses can be performed at 60/hour and can conveniently determine pyruvate and lactate in the ranges 0-5 mg. and 0-30 mg/100 ml. The methods give a high degree of analytical precision and good yields from recovery experiments.

1968 Journal of Clinical Pathology

92. Lactic acid release by intra-arterial adrenaline infusions before and after dibenyline, and its relationship to blood-flow changes in the human forearm Full Text available with Trip Pro

Lactic acid release by intra-arterial adrenaline infusions before and after dibenyline, and its relationship to blood-flow changes in the human forearm 13682618 1998 11 01 2018 11 30 0022-3751 157 1961 Jul The Journal of physiology J. Physiol. (Lond.) Lactic acid release by intraarterial adrenaline infusions before and after dibenyline, and its relationship to blood-flow changes in the human forearm. 328-34 ALLWOOD M J MJ COBBOLD A F AF eng Journal Article England J Physiol 0266262 0022-3751 0 (...) Lactates 0 Sympatholytics 0TTZ664R7Z Phenoxybenzamine 33X04XA5AT Lactic Acid YKH834O4BH Epinephrine OM Blood Circulation physiology Epinephrine pharmacology Forearm blood supply Hemodynamics Humans Infusions, Intra-Arterial Lactates metabolism Lactic Acid Phenoxybenzamine Sympatholytics pharmacology BLOOD CIRCULATION/physiology EPINEPHRINE/pharmacology FOREARM/blood supply LACTATES/metabolism SYMPATHOLYTICS/pharmacology 1961 7 1 1961 7 1 0 1 1961 7 1 0 0 ppublish 13682618 PMC1359955 J Physiol. 1949 Aug

1961 The Journal of physiology

93. ON THE BLOOD LACTIC ACID RESPONSE TO MEASURED EXERCISE IN HYPOXIC HUMAN SUBJECTS Full Text available with Trip Pro

ON THE BLOOD LACTIC ACID RESPONSE TO MEASURED EXERCISE IN HYPOXIC HUMAN SUBJECTS 16695540 2006 05 31 2008 11 20 0021-9738 27 2 1948 Mar The Journal of clinical investigation J. Clin. Invest. ON THE BLOOD LACTIC ACID RESPONSE TO MEASURED EXERCISE IN HYPOXIC HUMAN SUBJECTS. 176-86 Tepperman J J Yale Aeromedical Unit, Department of Physiology, Yale University School of Medicine, New Haven. Tepperman H M HM Patton B W BW eng Journal Article United States J Clin Invest 7802877 0021-9738 1948 3 1 0 0

1948 Journal of Clinical Investigation

94. The influence of lactic acid upon the dissociation curve of blood Full Text available with Trip Pro

The influence of lactic acid upon the dissociation curve of blood 16993032 2007 02 05 2008 11 20 0022-3751 41 5 1910 Dec 31 The Journal of physiology J. Physiol. (Lond.) The influence of lactic acid upon the dissociation curve of blood. 355-67 Barcroft J J Orbeli L L eng Journal Article England J Physiol 0266262 0022-3751 1910 12 31 0 0 1910 12 31 0 1 1910 12 31 0 0 ppublish 16993032 PMC1512907

1910 The Journal of physiology

95. Chenodeoxycholic acid sigma-tau - cerebrotendinous xanthomatosis

Conference of Harmonisation IEC Independent Ethic Committee LCA Lithocholic acid LDH Lactic Dehydrogenase MedDRA Medical Dictionary for Regulatory Activities MEPs Motor Evoked Potentials MMRM Mixed Model for Repeated Measures MMSE Mini Mental State Examination MRI Magnetic Resonance Imaging NCS Non-clinically Significant PT Preferred Term PTH Parathyroid Hormone RBC Red Blood Cell SAE Serious Adverse Event SAP Statistical Analysis Plan SAS Statistical Analysis System SD Standard Deviation SI (...) 40 2.6. Pharmacovigilance 40 2.7. Product information 42 2.7.1. User consultation 42 2.7.2. Additional monitoring 42 3. Benefit-risk balance 43 4. Recommendation 46 Assessment report EMA/650359/2016 Page 3/47 List of abbreviations ADR Adverse Drug Reaction AE Adverse Event ALT Alanine Aminotransferase AST Aspartate Aminotransferase ATC Anatomic Therapeutic Chemical classification system BUN Blood Urea Nitrogen CA Cholic acid CBC Complete Blood Count CDCA Chenodeoxycholic acid CI Confidence

2017 European Medicines Agency - EPARs

96. Dorsal root ganglion-derived Schwann cells combined with poly(lactic-co-glycolic acid)/chitosan conduits for the repair of sciatic nerve defects in rats Full Text available with Trip Pro

procedures with low cell yields or purity. In this study, we collected dorsal root ganglia from neonatal rats from which we obtained highly purified Schwann cells using serum-free melanocyte culture medium. The purity of Schwann cells (> 95%) using our method was higher than that using standard medium containing fetal bovine serum. The obtained Schwann cells were implanted into poly(lactic-co-glycolic acid)/chitosan conduits to repair 10-mm sciatic nerve defects in rats. Results showed that axonal (...) diameter and area were significantly increased and motor functions were obviously improved in the rat sciatic nerve tissue. Experimental findings suggest that serum-free melanocyte culture medium is conducive to purify Schwann cells and poly(lactic-co-glycolic acid)/chitosan nerve conduits combined with Schwann cells contribute to restore sciatic nerve defects.

2014 Neural Regeneration Research

97. Cholesterol-Lowering Potentials of Lactic Acid Bacteria Based on Bile-Salt Hydrolase Activity and Effect of Potent Strains on Cholesterol Metabolism In Vitro and In Vivo Full Text available with Trip Pro

. NBHK002, NBHK006, and NBHK007 could reduce apo B secretion by 33%, 38%, and 39%, respectively, after 24 h of incubation. The product PROBIO S-23 produced a greater decrease in the total concentration of cholesterol, low-density lipoprotein, TG, and thiobarbituric acid reactive substance in the serum or livers of hamsters with hypercholesterolemia compared with that of hamsters fed with a high-fat and high-cholesterol diet. These results show that the three probiotic strains of lactic acid bacteria (...) Cholesterol-Lowering Potentials of Lactic Acid Bacteria Based on Bile-Salt Hydrolase Activity and Effect of Potent Strains on Cholesterol Metabolism In Vitro and In Vivo This study collected different probiotic isolates from animal and plant sources to evaluate the bile-salt hydrolase activity of probiotics in vitro. The deconjugation potential of bile acid was determined using high-performance liquid chromatography. HepG2 cells were cultured with probiotic strains with high BSH activity

2014 The Scientific World Journal

98. [The significance of lactic acid in early diagnosis and goal-directed therapy of septic shock patients]. (Abstract)

group was defined using blood lactic acid concentration < 2 mmol/L as treatment guide target. Control group was defined according to the traditional diagnostic criteria of shock which systolic blood pressure was less than 90 mmHg (1 mmHg= 0.133 kPa) or systolic blood pressure value fell > 40 mmHg baseline or oliguria ( < 0.5 ml. kg-1.h-1) et al traditional septic shock diagnosis criteria and bundle treatment was performed. Organ dysfunction index, the sequential organ failure score (SOFA), acute (...) that of control group [15.38% (4/26) vs. 16.13% ( 5/31), Χ2=0.000, P=1.000]. The 28-day mortality of lactic group was lower than that of control group [26.92 % (7/26) vs. 54.84% (17/31). Χ2=4.520, P=0.033].By blood lactic acid monitoring, inadequacy of organization perfusion i.e. septic shock can be found in the early stage, thus early intervention can be performed and improve resuscitation result and reduce the mortality of septic shock patients. Blood lactic acid ≥ 4 mmol/L can be used as one

2014 Zhonghua wei zhong bing ji jiu yi xue Controlled trial quality: uncertain

99. A Randomized Double Blind Controlled Safety Trial Evaluating d-Lactic Acid Production in Healthy Infants Fed a Lactobacillus reuteri-containing Formula. Full Text available with Trip Pro

was collected before study formula intake and at all visits up to 112 days and blood at 14 days.d-Lactic acid concentration in the probiotic group was below the non-inferiority margin at 28 days: treatment effect -0.03 (95% confidence interval [CI]: [-0.48 to 0.41]) mmol/mol creatinine but was above the non-inferiority margin at 7 and 14 days-treatment effect 0.50 (95% CI: [0.05-0.96]) mmol/mol creatinine and 0.45 (95% CI: [0.00-0.90]) mmol/mol creatinine, respectively. Blood acid excess and pH (...) A Randomized Double Blind Controlled Safety Trial Evaluating d-Lactic Acid Production in Healthy Infants Fed a Lactobacillus reuteri-containing Formula. d-Lactic acidosis in infants fed lactic acid bacteria-containing products is a concern.The primary objective of this non-inferiority trial was to compare urinary d-lactic acid concentrations during the first 28 days of life in infants fed formula containing Lactobacillus reuteri (1.2 × 10(6) colony forming units (CFU)/ml) with those fed

2014 Nutrition and metabolic insights Controlled trial quality: predicted high

100. CRACKCast E124 – Acid-Base Disorders

the cerebrospinal fluid. As the serum pH rises, minute ventilation slows and carbon dioxide, which readily crosses the blood-brain barrier, delivers an additional acid load to the CNS. Hypokalemia, which can cause respiratory muscle weakness, impairing respiratory compensation, hypocalcemia, hypernatremia Volume overload Hyperosmolality Overshoot alkalosis So what to do??….administration of sodium bicarbonate is unlikely to be beneficial in most cases of acidemia caused by endogenous acid production (eg, lactic (...) of bicarbonate (HCO3) and carbon dioxide (Paco2) = [1.5 × serum HCO3 − ] + [8 ± 2]; when two of these variables are known, the third may be calculated. Most blood gas analyzers measure pH and Paco2 and report a calculated [HCO3 − ]. When only a primary disturbance and its corresponding compensation are present, it is described as a simple acid-base disorder. A mixed acid-base disorder exists when more than one primary disturbance occurs simultaneously. Key thought process: Is this a simple ABD or a mixed ABD

2017 CandiEM

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