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161. Guidelines for Blood Glucose Monitoring and Treatment of Hypoglycemia in Term and Late-Preterm Neonates

feeding is withheld, this phenomenon is self-limited, withoutclinicalsigns,andconsideredtobepartofadaptationto postnatallife,asglucoselevelsspontaneouslyrisewithinthe?rst 24hoursafterbirth(forsome,itisevenlongerbutstillphysio- logical). 2–6 Mostneonatescompensateforthis‘‘physiological’’ low blood glucose with endogenous fuel production through gluconeogenesis,glycogenolysis,andketogenesis,collectively called‘‘counter-regulation.’’Eveninthosesituationswherelow blood glucose concentrations do develop (...) Guidelines for Blood Glucose Monitoring and Treatment of Hypoglycemia in Term and Late-Preterm Neonates ABM Protocol ABM Clinical Protocol #1: Guidelines for Blood Glucose Monitoring and Treatment of Hypoglycemia in Term and Late-Preterm Neonates, Revised 2014 Nancy Wight, 1,2 Kathleen A. Marinelli, 3,4 and The Academy of Breastfeeding Medicine A central goal of The Academy of Breastfeeding Medicine is the development of clinical protocols for managing

2014 Academy of Breastfeeding Medicine

162. Update: Ambulatory Blood Pressure Monitoring in Children and Adolescents

Update: Ambulatory Blood Pressure Monitoring in Children and Adolescents Update: Ambulatory Blood Pressure Monitoring in Children and Adolescents | Hypertension Search Hello Guest! Login to your account Email Password Keep me logged in Search April 2019 March 2019 February 2019 January 2019 Free Access article Share on Jump to Free Access article Update: Ambulatory Blood Pressure Monitoring in Children and Adolescents A Scientific Statement From the American Heart Association , MD, MS, Chair (...) in Youth Committee of the Council on Cardiovascular Disease in the Young Originally published 3 Mar 2014 Hypertension. 2014;63:1116–1135 You are viewing the most recent version of this article. Previous versions: Introduction Ambulatory blood pressure monitoring (ABPM) has established roles in the evaluation and management of hypertension in adults but has only been applied to children and adolescents more recently. In 2008, the American Heart Association (AHA) issued the first set of consensus

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2014 American Heart Association

163. Blood sampling, neonatal capillary

the following equipment ( ): gloves and aprons ( ) cotton wool or gauze capillary tube and/or blood bottle Tenderfoot® or other age/size appropriate automated incision device ( ) clean tray to hold equipment sharps disposal box ( ) Selecting an appropriate device An appropriately sized and age-appropriate automated incision device (eg Tenderfoot® designed specifically for use on neonates should be selected ). Skin puncture must be no deeper than 2mm for term neonates. A penetrative depth of no more than 1mm (...) ( Tenderfoot® Heel Incision Device) . There is no need to discard the first drop - the first drop of blood can be used if the baby’s heel has been cleaned thoroughly ( ). While maintaining grip, hold the heel so that blood is allowed to hang downwards ( ). Gently but firmly compress the baby’s heel to form a large droplet of blood ( ). Do not squeeze the foot in an attempt to increase blood flow ( ). Hold the capillary tube or blood bottle to the blood droplet and touch ( ). See figure 4 below ( Tenderfoot

2014 Publication 1593

164. Diagnostic value of ex vivo pleural fluid interferon-gamma versus adapted whole-blood quantiferon-TB gold in tube assays in tuberculous pleural effusion (PubMed)

Quantiferon-TB Gold In tube assay (QFT- IT) in blood and its adapted variants, using pleural fluid or isolated pleural fluid cells in the diagnosis of pleural TB.Thirty-eight patients with pleural effusion of unknown etiology presented at Assiut University Hospital, Egypt, were recruited. Blood and pleural fluid were collected at presentation for INF-γ assays. Ex vivo pleural fluid INF-γ levels, QFT-IT in blood and its adapted variants were compared with final diagnosis as confirmed by other tools (...) Diagnostic value of ex vivo pleural fluid interferon-gamma versus adapted whole-blood quantiferon-TB gold in tube assays in tuberculous pleural effusion Noninvasive diagnosis of pleural tuberculosis (TB) remains a challenge due to the paucibacillary nature of the disease. As Mycobacterium tuberculosis (MTB)-specific T cells are recruited into pleural space in TB effusion; their indirect detection may provide useful clinical information.Evaluation of pleural fluid interferon (INF)-γ levels vs

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2012 Annals Of Thoracic Medicine

165. [A comparison of the rates of hemolysis and repeated blood sampling using syringe needles versus vacuum tube needles in the emergency department]. (PubMed)

sampling to determine electrolyte level. ED patients were randomly assigned to either the syringe group or the vacuum tube group. All blood samples were collected by experienced ED nurses and hemolysis was determined by experienced laboratory technologists. Data were analyzed using Fisher's exact test and binary logistic regression.One hundred forty-five valid samples were collected (74 in the syringe group versus 71 in the vacuum tube group). 5 of 74 (6.8%) blood samples in the syringe group and 8 (...) [A comparison of the rates of hemolysis and repeated blood sampling using syringe needles versus vacuum tube needles in the emergency department]. This study was done to compare the rates of hemolysis and repeated sampling in blood samples obtained by a syringe needle versus a vacuum tube needle.A randomized, prospective study was used to evaluate the differences between the two blood sampling methods. The study group consisted of patients seen in the emergency department (ED) for blood

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2012 Journal of Korean Academy of Nursing Controlled trial quality: uncertain

166. Addition of microRNA Blood Test to Lung Cancer Screening Low Dose CT

available diagnostic information (LDCT, subsequent diagnostic imaging studies, biopsy results and surgical pathology results) obtained during at least 12 months of follow-up. Biospecimen Retention: Samples With DNA Blood will be drawn from all patients at the time of study enrollment prior to LDCT scanning (10cc blood divided into 2 PAXgene tubes) Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk (...) Addition of microRNA Blood Test to Lung Cancer Screening Low Dose CT Addition of microRNA Blood Test to Lung Cancer Screening Low Dose CT - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Addition of microRNA

2018 Clinical Trials

167. Reference intervals for a complete blood count on an automated haematology analyser Sysmex XN in healthy adults from the southern metropolitan area of Barcelona (PubMed)

blood count (CBC) on a Sysmex XN haematology analyser in healthy adults from the southern metropolitan area of Barcelona (Spain).A total of 213 apparently healthy adults who received a general health examination at Hospital Universitari de Bellvitge were recruited to this study. Blood samples collected in K3EDTA tubes were analysed on a Sysmex XN. Statistically relevant gender based partition was assessed, outliers removed, and the reference intervals calculated in concordance with Clinical (...) Reference intervals for a complete blood count on an automated haematology analyser Sysmex XN in healthy adults from the southern metropolitan area of Barcelona The examination of peripheral blood is routinely used as a basic test in daily medical practice. Reliable reference intervals are necessary to avoid misdiagnoses, and the establishment of those intervals is an important task for clinical laboratories.The aim of the present study was to establish the reference intervals for complete

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2018 EJIFCC

168. Capillary Blood Volume and Pain Perception Obtained in a Process of Puncturing With Different Safety Lancets

way and was performed by medical staff trained from lancing procedure described in the Protocol. Total blood collection time was recorded in the source documentation and then volume of the blood was measured using a calibrated ruler. Other Name: Cambridge Sensors lancet Outcome Measures Go to Primary Outcome Measures : Volume (microliters) of blood in the capillary tube [ Time Frame: The blood volume was noted after 20 seconds ] The amount of capillary blood volume collected after a single lancing (...) of the fingertip. Volume (microliters) of blood in the capillary tube [ Time Frame: The blood volume was noted until the end of bleeding or up to 2 minutes time ] The amount of capillary blood volume collected after a single lancing of the fingertip. Secondary Outcome Measures : Pain perception [ Time Frame: directly after lancing ] The intensity of pain perceived by the patient was assessed with the use of the numeric Visual Analog Scale (VAS). The Subject marked on the scale the number from 0 ("no pain

2018 Clinical Trials

169. A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction (PubMed)

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction We have developed novel methods for the isolation and characterization of tumor-derived circulating ribonucleic acid (cRNA) for blood-based liquid biopsy. Robust detection of cRNA recovered from blood represents a solution to a critical unmet need in clinical diagnostics. The test begins with the collection of whole blood into blood collection tubes

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2018 Journal of visualized experiments : JoVE

170. Changes in cytokine responses to TB antigens ESAT-6, CFP-10 and TB 7.7 and inflammatory markers in peripheral blood during therapy (PubMed)

), and at the end of anti-TB treatment (Tend). We measured the levels of Interferon (IFN)-γ, interleukin (IL)-2, IL-12, IL-10, IL-13 and tumor necrosis factor (TNF)-α in supernatants collected from the QuantiFERON-TB Gold In-Tube assay (QFT-GIT), as well as the WBC, neutrophil, platelet count and neutrophil to lymphocyte ratio (NLR) in whole blood. Compared with baseline levels, WBC, neutrophil, and platelet counts were significantly lower following treatment. In addition, the NLR after treatment significantly (...) Changes in cytokine responses to TB antigens ESAT-6, CFP-10 and TB 7.7 and inflammatory markers in peripheral blood during therapy Multiple cytokines and inflammatory markers control TB infection. We aimed to investigate the changes in multiple cytokines and inflammatory markers in active TB patients following anti-TB drug therapy. Twenty-nine patients with active TB were recruited prospectively between December 2010 and July 2017. Blood samples were collected before (T0), after 2 months (T2

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2018 Scientific reports

171. Delayed double reading of whole blood clotting test (WBCT) results at 20 and 30 minutes enhances diagnosis and treatment of viper envenomation (PubMed)

Delayed double reading of whole blood clotting test (WBCT) results at 20 and 30 minutes enhances diagnosis and treatment of viper envenomation The whole blood clotting test (WBCT) is a simple test of coagulation that is often used in the assessment, diagnosis, and therapeutic monitoring of snakebite patients in sub-Saharan Africa. WBCT requires only a clean glass tube and several milliliters of venous blood and is ideal for use in poorly equipped health centers throughout the rural areas where (...) collection in 23 patients treated for snake envenomation in Bembèrèkè, northern Benin.WBCT results were identical at both reading times in patients without coagulopathy or when coagulation was restored permanently following a single dose of antivenom. Out of 17 patients with coagulopathy, 14 showed discrepancies between WBCT20 and WBCT30 results in at least one pair of serial evaluations. These could be completely contradictory results (e.g. normal clot at WBCT20 and no clot at WBCT30) or a marked

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2018 The journal of venomous animals and toxins including tropical diseases

172. Biochemical changes in stored donor units: implications on the efficacy of blood transfusion (PubMed)

each participant in EDTA tubes before transfusion (for pre-transfusion hemoglobin [Hb] estimation) and after transfusion (for post-transfusion Hb estimation). Each crossmatched unit was sampled to collect plasma for pH, lactate and potassium assays. Data were analyzed with STATA version 12.0.A total of 200 blood transfusion recipients aged 1-60 years were enrolled in the study. Up to 60% of the participants were females. The pH of the stored blood dropped from 7.4 to 7.2 in the first 3 days to ~7.0 (...) the biochemical changes that occur in blood units during storage and to project the impact of these changes on transfusion.The study protocol was approved by the Faculty of Medicine Research Ethics committee of Mbarara University of Science and Technology. A total of 200 blood recipients were categorized into two study arms: group I received fresh blood (n=100) and group II received old blood (n=100), who were formally consented and recruited consecutively. A total of 2 mL of venous blood was collected from

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2018 Journal of blood medicine

173. HEARTBiT: Multi-Marker Blood Test for Acute Cardiac Transplant Rejection

and NR as ordered variables. Biospecimen Retention: Samples With DNA Whole blood samples to be collected in four (4) tubes (approx. 15mL or 3 teaspoons) consisting of: 1 - 6 mL lavender top (EDTA) tube (plasma) 1 - 4 mL red top tube (serum) 2 - 2.5 mL PAXgene tubes (RNA) Blood processing (fractionation) of plasma and serum tubes following SOP guidelines will result in collection of: 8 - 0.5mL plasma aliquots 1 - 0.5mL buffy coat DNA sample 6 - 0.5mL serum aliquots Eligibility Criteria Go (...) HEARTBiT: Multi-Marker Blood Test for Acute Cardiac Transplant Rejection HEARTBiT: Multi-Marker Blood Test for Acute Cardiac Transplant Rejection - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. HEARTBiT

2018 Clinical Trials

174. A Pilot Study- Monitoring Cerebral Blood Flow in Neonates With Congenital Heart Defects

at the same day and one and two days after, for 3 hours per day. Additional standard of care parameters will be collected :Heart rate, Mean Arterial Blood Pressure, Saturation, Ventilator rate, Medications, Blood gases ( blood tests), Echocardiogram, pre-surgery Head US,. additional examination will be performed intended for the study: two post surgery Head US, S100B biomarker for brain injury and Neurological examinations prior and 7 days post- surgery( By standardized questionnaires). Sample size: 55 (...) used to measure relative changes in blood flow. The device monitors regional micro circulatory blood flow in tissues, by using sensors placed near the area of interest. Outcome Measures Go to Primary Outcome Measures : Change in c-Flow3310-P following routine maneuvers [ Time Frame: 3 hours monitoring per day, for 4 days ] Changes will be measured following routine maneuvers such as suction, leg lifting, Blood sample, changing position, feeding, presence of feeding tube etc. Change= (CFI

2018 Clinical Trials

175. Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer

-guided radiation therapy (GRT). Participant will complete the quality-of-life questionnaire. Wherever possible, blood samples will be collected at the same time as routine blood draws and/or when a catheter (needle and tube) is placed. However, if a blood draw is not planned, one will be scheduled for this study. Length of Study: Participation on the study will be over after the follow-up visit. Participant will be taken off study early if radiation treatment is stopped early. Follow-up: One (1) time (...) Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Biopsy proven diagnosis of squamous cell carcinoma (SCC) of head and neck mucosa. Clinical evidence should be documented, and may consist of imaging, endoscopic evaluation, palpation, and should be sufficient to estimate the size of the primary for purposes of T staging. Age ≥18 years No distant metastases, based on routine staging workup. Consent for blood collection

2018 Clinical Trials

176. Haplo-Identical Transplantation for Severe Aplastic Anemia and Hypo-Plastic MDS Using Peripheral Blood Stem Cells and Post-Transplant Cyclophosphamide for GVHD Prophylaxis

blood hematopoietic stem cells from a family member plus chemotherapy. Eligibility: Recipients ages 4 55 with SAA or MD and their relative donors ages 4 75 Design: Recipients will have: Blood, urine, heart, and lung tests Scans Bone marrow sample Recipients will need a caregiver for several months. They may make fertility plans and a power of attorney. Donors will have blood and tissue tests, then injections to boost stem cells for 5 7 days. Donors will have blood collected from a tube in an arm (...) ) ) Study Details Study Description Go to Brief Summary: Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MD) cause serious blood problems. Stem cell transplants using bone marrow or blood plus chemotherapy can help. Researchers want to see if using peripheral blood stem cells (PBSCs) rather than bone marrow cells works too. PBSCs are easier to collect and have more cells that help transplants. Objectives: To see how safely and effectively SAA and MD are treated using peripheral

2018 Clinical Trials

177. Effect of Steroid Administration on Maternal Blood Levels of hLPCAT1 mRNA

with all other relevant clinical labs (in PAX gene tubes) on admission, 24hrs and 48hrs after the course of steroids is initiated. Samples will also be collected 1 and 2 weeks later to see if steroid effect degrades over time. This would have immense clinical implication, especially when it comes to rescue doses. Investigators will also correlate measures of neonatal outcomes (such as apgar scores, blood gases, NICU admission, need to go on respiratory/ventilator support) to the most recent maternal (...) for respiratory support, need for ventilator) with levels of hLPCAT1 in labor. METHODOLOGY The first group will consist of patients with normal pregnancies who present for routine prenatal care between 32- 36 6/7 weeks. Once consented and enrolled in the study, participants will give a small (half a teaspoon) blood sample every other week until reaching 37 weeks. In group 2, pregnant women who present for rule-out preterm labor will be offered participation in the study. Blood samples will be collected along

2018 Clinical Trials

178. Valid Biomarkers in Blood to Predict the Response to Therapy in Prostate Cancer Patients

in EDTA tube for analysis of biological biomarkers in different time points. Condition or disease Intervention/treatment Prostate Cancer Other: biological samples collection and analysis Detailed Description: Participants to the study will be assigned to 5 cohorts according to the stage of disease and planned antitumor treatment at time of study entry. Group 0 (set-up): blood sampling and rectal swab will be collected at a single time-point during the PC treatment. No follow-up is required. Group 1a (...) 24, 2018 Last Update Posted : January 4, 2019 See Sponsor: Andrea Alimonti Collaborator: Clinical Trial Unit Ente Ospedaliero Cantonale Information provided by (Responsible Party): Andrea Alimonti, Oncology Institute of Southern Switzerland Study Details Study Description Go to Brief Summary: Participants to the study will be assigned to 5 cohorts according to the stage of disease and planned antitumor treatment at time of study entry. In all patients, 12 ml of blood sample will be collected

2018 Clinical Trials

179. Comparison Between K3EDTA and Lithium Heparin as Anticoagulant to Isolate Bovine Granulocytes From Blood (PubMed)

of the anticoagulants K3EDTA or lithium heparin and the effect of different RBCs lysis methods on bovine granulocyte population from fresh blood of healthy cows after density gradient centrifugation were investigated. Venous blood from healthy cows was collected in K3EDTA and lithium heparin tubes. Density gradient centrifugation to separate granulocytes from other cells was conducted using Biocoll. Then, RBCs were lysed with hypotonic water or 0.2% sodium chloride (NaCl). Immediately after isolation, harvest (...) Comparison Between K3EDTA and Lithium Heparin as Anticoagulant to Isolate Bovine Granulocytes From Blood Granulocytes play a key role in the defense against invading pathogens. To study granulocyte functions, the isolation of a pure and active cell population from fresh blood is required. Anticoagulants and red blood cells (RBCs) lysis used in the isolation procedure may influence cell harvest, cell marker expression, and pre-activation of cells. In this study, the influence

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2018 Frontiers in immunology

180. Comparison of heel stick sample with placental blood sample for pretransfusion testing. (PubMed)

testing potentially reduces the amount of blood collected from newborns for initial laboratory tests.Placental samples were collected for pretransfusion tests at birth from 32 newborns with less than 2000 g birthweight and less than 35 weeks to compare the results with the heel stick samples from the same newborns. ABO and D typing, direct antiglobulin test (DAT) with IgG, and antibody screen tests were performed on these sample pairs. For ABO and D typing both tube and gel methods were used (...) Comparison of heel stick sample with placental blood sample for pretransfusion testing. Published studies demonstrate that placental blood samples provide acceptable results for various laboratory tests, but these studies did not include pretransfusion testing. The aim of this study was to show concordance between heel stick and placental blood sample pairs for pretransfusion testing and to validate tube and gel method for placental samples. Using placental blood samples for pretransfusion

2018 Transfusion

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