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Blood Collection Tube

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121. In Vivo Recovery and Survival Study of Platelets Collected on Trima Accel System and Stored in InterSol Solution

in InterSol Solution Actual Study Start Date : July 26, 2017 Actual Primary Completion Date : November 24, 2017 Actual Study Completion Date : November 24, 2017 Arms and Interventions Go to Arm Intervention/treatment Experimental: Platelets stored in InterSol Platelets collected on the Trima Accel system and stored in 65% InterSol/35% plasma Device: Trima Accel system A platelet apheresis procedure involves connecting the blood in the donor's vein through tubing to a machine that separates the blood (...) components. After the separation, the desired component of the blood is removed (platelets and plasma), while the remainder of the blood components are reinfused back into the patient. To prevent clotting, an anticoagulant (ACDA) is used throughout the procedure. Following each blood collection, Platelet Additive Solution (PAS), InterSol, will be added to the platelet product to prepare the final product for 5 day storage. The entire procedure is painless and should take 90 to 120 minutes. Outcome

2017 Clinical Trials

122. A Trial of Early Percutaneous Catheter Drainage of Sterile Pancreatic Fluid Collections in Severe Acute Pancreatitis

A Trial of Early Percutaneous Catheter Drainage of Sterile Pancreatic Fluid Collections in Severe Acute Pancreatitis A Trial of Early Percutaneous Catheter Drainage of Sterile Pancreatic Fluid Collections in Severe Acute Pancreatitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. A Trial of Early Percutaneous Catheter Drainage of Sterile Pancreatic Fluid Collections in Severe Acute Pancreatitis (EPCDSAP) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2017 Clinical Trials

123. Prevalence and Identification of Serum Markers Associated with Vertical Transmission of Hepatitis B in Pregnant Women in Yaounde, Cameroon Full Text available with Trip Pro

Prevalence and Identification of Serum Markers Associated with Vertical Transmission of Hepatitis B in Pregnant Women in Yaounde, Cameroon To determine the prevalence of Hepatitis B Virus (HBV) infection in pregnant women and identify markers associated with vertical transmission of HBV.Prospective and cross-sectional study over 10 months on 298 pregnant women attending antenatal clinics in the Cité Verte and Efoulan District hospitals in Cameroon. A dry tube blood collection was performed (...) on all pregnant women and babies born to HBsAg-positive mothers. Serum from the women was used to test for HBsAg through immunochromatography and then confirmed by ELISA. The test for HBeAg, HBeAb and HBcAb and dosage of transaminases were performed on the serum of HBsAg-positive women. Only HBsAg was tested in babies within 24 hours after birth.HBsAg was present in 23 (7.7%) mothers while 275 (92.3%) tested negative. Due to loss to follow-up, we assessed vertical transmission in 20 babies born to20

2017 International journal of MCH and AIDS

124. Factors That Contribute to Indeterminate Results from the QuantiFERON-TB Gold in-tube Test in Patients With Inflammatory Bowel Disease. Full Text available with Trip Pro

Factors That Contribute to Indeterminate Results from the QuantiFERON-TB Gold in-tube Test in Patients With Inflammatory Bowel Disease. The QuantiFERON-Tuberculosis Gold In-Tube (QFT-GIT) (QIAGEN Group, Hilden, Germany) test is widely used to screen for latent Mycobacterium tuberculosis infection in patients with inflammatory bowel diseases (IBD) before treatment with a tumor necrosis factor antagonist. The test frequently produces indeterminate results, prompting additional testing. We (...) evaluated factors associated with indeterminate results from the QFT-GIT test among patients with IBD.We conducted a case-control study among eligible adults with QFT-GIT test results and a concomitant diagnosis of IBD receiving care at a tertiary referral center from 2011 through 2013. We compared patients with IBD with indeterminate and determinate (positive or negative) results from the QFT-GIT test. We collected data on patient demographics, clinical features, laboratory parameters, and medication

2017 Clinical Gastroenterology and Hepatology

125. Variants in MTHFR gene and neural tube defects susceptibility in China. (Abstract)

in our study. Tag-SNPs were identified in HapMap Databases. Blood samples were collected from all subjects to further extract the genomic DNAs by TaqMan Blood DNA kits. We also carried out a meta-analysis based on previous published studies to further examine the association between MTHFR polymorphisms and NTD. In case-control study analysis, two SNPs were identified to be associated with NTD risk. The 677 C > T genetic variant was correlated with increased risk of NTD-affected pregnancy. However (...) Variants in MTHFR gene and neural tube defects susceptibility in China. Neural tube defect (NTD) is a severe congenital birth abnormalities involving incomplete neural tube closure. 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene plays key role in folate cycle and methylation cycle, which could affect the DNA synthesis, repair and methylation. In this study, we aim to investigate the correlation between MTHFR polymorphisms and NTD-affected pregnancy. There were 444 participants involved

2017 Metabolic brain disease

126. Duodenal and ileal glucose infusions differentially alter gastrointestinal peptides, appetite response, and food intake: a tube feeding study. Full Text available with Trip Pro

), a standardized breakfast meal was followed midmorning by a 90-min infusion of isotonic glucose (15 g, 235 kJ) or saline to the duodenum or ileum. Appetite ratings were assessed with the use of visual analog scales (VASs), blood samples collected, and ad libitum energy intake (EI) measured at lunch, afternoon snack, and dinner.Results: Thirteen participants completed the 4 infusion days. There was a significant effect of nutrient infused and site (treatment × time, P < 0.05) such that glucose-to-ileum altered (...) Duodenal and ileal glucose infusions differentially alter gastrointestinal peptides, appetite response, and food intake: a tube feeding study. Background: Activation of the ileal brake through the delivery of nutrients into the distal small intestine to promote satiety and suppress food intake provides a new target for weight loss. Evidence is limited, with support from naso-ileal lipid infusion studies.Objective: The objective of the study was to investigate whether glucose infused

2017 American Journal of Clinical Nutrition Controlled trial quality: uncertain

127. Selective secretion of microRNAs from lung cancer cells via extracellular vesicles promotes CAMK1D-mediated tube formation in endothelial cells Full Text available with Trip Pro

adenocarcinoma extracellular vesicles compared to the donor cells from which they were derived. Two well-known tumor suppressors, miR-143-3p and miR-145-5p, were also enriched in serum samples collected during surgery from blood vessels draining directly from lung adenocarcinoma tumor beds. Recently, both miRNAs were found to promote neoangiogenesis in endothelial cells in mouse models of lung adenocarcinoma through targeting of CAMK1D, an inhibitory kinase that can impair angiogenesis when over-expressed (...) Selective secretion of microRNAs from lung cancer cells via extracellular vesicles promotes CAMK1D-mediated tube formation in endothelial cells Extracellular vesicles (EVs) are key signaling mediators between cancer cells and their supporting stroma, and regulate critical processes such as invasion, metastases, and angiogenesis. We have identified a subset of miRNAs (miR-142-3p, miR-143-3p, miR-145-5p, miR-150-5p, miR-223-3p, miR-451a, miR-486-5p, miR-605-5p) that are enriched in lung

2017 Oncotarget

128. The new Greiner FC-Mix tubes equal the old Terumo ones and are useful as glucose stabilizer after prolonged storage of samples Full Text available with Trip Pro

The new Greiner FC-Mix tubes equal the old Terumo ones and are useful as glucose stabilizer after prolonged storage of samples The aim of our study is to compare new Greiner tubes containing granulated citrate buffer with the Terumo ones and to verify if they are suitable for glucose stabilization after prolonged storage.In Study 1, blood was collected in two Terumo and two Greiner tubes from 40 healthy volunteers. Samples were stored at room temperature (RT) for 1 and 2 hours, respectively (...) . Comparison was made by Deming regression. In Study 2, glucose was measured in a reference tube (N = 50), according to the ADA-NACB guidelines and in aliquots of Greiner samples maintained un-centrifuged at RT for 1, 2, 4 (N = 50) and 24, 48, 72 hours (N = 35).There were insignificant mixed biases between the Terumo and Greiner tubes. Compared to reference (5.3 mmol/L), glucose concentration in the new tubes was 5.4 (P < 0.05), 5.4 (P < 0.05), 5.3 (P = 0.265), 5.2 (P = 0.156), 5.3 (P < 0.05) and 5.2 (P

2017 Biochemia medica

129. Effects of one directional pneumatic tube system on routine hematology and chemistry parameters; A validation study at a tertiary care hospital Full Text available with Trip Pro

Effects of one directional pneumatic tube system on routine hematology and chemistry parameters; A validation study at a tertiary care hospital The validation of sample stability through pneumatic tube system (PTS) is essential. The objective of this study was to evaluate the effects of PTS transportation on laboratory results.Paired EDTA and SST blood samples were collected from 56 randomly selected patients. Laboratory parameters were compared between PTS group and hand-delivered group.No (...) statistical differences were observed for complete blood counts, white blood cell differential parameters, erythrocyte sedimentation rate and most chemistry parameters between PTS and hand-delivered transport procedures. Mean platelet volume results obtained from samples transported through PTS were lower than that obtained from samples transported through hand-delivered method (P = 0.001). The results of aspartate aminotransferase (P = 0.000), lactate dehydrogenase (P = 0.000), and hemolysis index (P

2017 Practical Laboratory Medicine

130. Small-Volume Tubes to Reduce Anemia and Transfusion (STRATUS)

): Population Health Research Institute Study Details Study Description Go to Brief Summary: STRATUS will evaluate the use of small-volume ("soft-draw") blood collection tubes for laboratory testing in reducing anemia and transfusion in intensive care unit patients without significant adverse consequences. This is a simple, cost-neutral intervention that could improve the quality of patient care and reduce the harms of frequent laboratory testing. Condition or disease Intervention/treatment Blood Loss (...) to Group/Cohort Intervention/treatment Control (Before) Period Use of standard-volume blood collection tubes (6 weeks) Device: Standard-Volume Standard-volume (4 - 6 mL Vacutainer tubes, Beckton Dickinson) ethylenediaminetetraacetic acid (EDTA), lithium-heparin, citrate, fluoride and silica tubes. Intervention (After) Period Use of small-volume ("soft-draw") blood collection tubes (6 weeks following 2-week washout period) Device: Small-Volume Small-volume (2 - 3 mL "soft-draw" Vacutainer tubes, Beckton

2017 Clinical Trials

131. Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer

and procedures done for research purposes only during this time include archival tumor tissue collection, fresh research biopsy, and blood sample collection for biomarker/genetic/immune research. Participants will also be asked if they agree to an optional fresh research biopsy at disease progression Eligible participants will receive the following every 21 day cycle: Pembrolizumab, intravenously, at 200 mg, on Day 1 of every cycle. DPX-Survivac, by injection under the skin of the upper thigh in clinic (...) and procedures done for research purposes only include additional blood sample collection and a second fresh research biopsy for biomarker/genetic/immune research. Participants who benefit from the study treatment may be able to receive additional treatment if they progress after stopping the study treatment. When participants are taken off the study treatment permanently, they will be asked to return to the study site for an End of Study Treatment visit about 30 days after stopping the study treatment

2017 Clinical Trials

132. P53MVA and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Go to Primary Outcome Measures : Response rate (CR+PR) [ Time Frame: Up to 24 months ] Secondary Outcome Measures : Biomarker analysis [ Time Frame: Up to 24 months ] Peripheral blood samples will be collected pre- and post-immunization for assessment of anti-p53 T cell responses and immunophenotyping. Immunosuppressive cell types (myeloid-derived suppressor cell, regulatory T cells) and other selected lymphocyte subsets and markers including PD-1, PDL-1 and PDL-2 will be quantified (...) P53MVA and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer P53MVA and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2017 Clinical Trials

133. Blood Collection From People With Ovarian Cancer

of the chest, abdomen, and pelvis and/or an MRI. For these scans, they will lie in a machine that takes pictures of their body. A small amount of blood (two tubes) will be collected by needle during one visit. Condition or disease Ovarian Cancer Cancer of the Ovary Ovarian Neoplasms Detailed Description: Background: Using both in vitro and in vivo assays we have shown that human monocytes primed with Interferons alpha and gamma are tumoricidal and are capable of killing a number of tumor cell lines (...) and human tumors implanted into immunocompromised mice. We have shown that monocytes isolated through elutriation at the NIH blood bank and monocytes isolated from anticoagulated peripheral blood from healthy women from the NIH blood bank are equally capable of killing tumor cells. No data have been collected as to whether monocytes from patients with Ovarian, Primary Peritoneal, or Fallopian Tube Cancer have tumoricidal properties. In addition, native host anti-tumor cell mediated immune mechanisms may

2014 Clinical Trials

134. Evaluation of a solid matrix for collection and ambient storage of RNA from whole blood. Full Text available with Trip Pro

Evaluation of a solid matrix for collection and ambient storage of RNA from whole blood. Whole blood gene expression-based molecular diagnostic tests are becoming increasingly available. Conventional tube-based methods for obtaining RNA from whole blood can be limited by phlebotomy, volume requirements, and RNA stability during transport and storage. A dried blood spot matrix for collecting high-quality RNA, called RNA Stabilizing Matrix (RSM), was evaluated against PAXgene® blood collection (...) tubes.Whole blood was collected from 25 individuals and subjected to 3 sample storage conditions: 18 hours at either room temperature (baseline arm) or 37°C, and 6 days at room temperature. RNA was extracted and assessed for integrity by Agilent Bioanalyzer, and gene expression was compared by RT-qPCR across 23 mRNAs comprising a clinical test for obstructive coronary artery disease.RSM produced RNA of relatively high integrity across the various tested conditions (mean RIN ± 95% CI: baseline arm, 6.92

2014 BMC Clinical Pathology

135. Opportunities to improve storage and transportation of blood specimens for CD4 testing in a rural district in Zimbabwe using BD vacutainer CD4 stabilization tubes: a stability and diagnostic accuracy study. Full Text available with Trip Pro

Opportunities to improve storage and transportation of blood specimens for CD4 testing in a rural district in Zimbabwe using BD vacutainer CD4 stabilization tubes: a stability and diagnostic accuracy study. CD4+ T-cell testing of blood specimens collected in standard EDTA Vacutainer tubes and transported at ambient temperature, must be completed within 48 hours with the BD FACSCount™ flow cytometer, restricting specimen collection in remote clinics with no on-site testing and limited specimen (...) transport services. We conducted a study in Buhera District, Zimbabwe, to assess the stability and accuracy of CD4+ T-cell results of samples collected in Stabilization Tubes (ST) and stored at ambient temperature for varying time periods.Paired EDTA and ST samples were collected from 51 HIV-positive patients aged 18 years and older. CD4+ T-cell testing was done on arrival in the laboratory (Day 0). ST samples were retested on Days 3, 5, and 7. Nineteen ST samples were stored for an additional week

2014 BMC Infectious Diseases

136. Differential expression of miRNAs in acute myeloid leukemia quantified by Nextgen sequencing of whole blood samples. Full Text available with Trip Pro

, prior to induction chemotherapy, and 9 controls. Two and a half ml of whole blood was collected in Paxgene RNA tubes. MiRNA was purified using RNeasy mini column (Qiagen). We sequenced approximately 1000 miRs from each of 10 AML patients and 9 controls. In subset analysis, patients with NPM1 and FLT3 mutations showed the greatest number of miRNAs (63) with expression levels that differed from control with adjusted p-value of 0.05 or less. Some of these miRs have been described previously (...) Differential expression of miRNAs in acute myeloid leukemia quantified by Nextgen sequencing of whole blood samples. New approaches are needed for understanding and treating acute myeloid leukemia (AML). MicroRNAs (miRs) are important regulators of gene expression in all cells and disruption of their normal expression can lead to changes in phenotype of a cell, in particular the emergence of a leukemic clone. We collected peripheral blood samples from 10 adult patients with newly diagnosed AML

2019 PLoS ONE

137. The Evaluation of Three Different Bottles in BACTEC 9240 Automated Blood Culture System and Direct Identification of Candida species to Shorten the Turnaround Time of Blood Culture. (Abstract)

the turnaround time from blood culture collection to final identification in candidemia.Sixty clinical bloodstream isolates of Candida were included, and Plus Aerobic/F, Peds Plus/F and Mycosis IC/Fbottles were used with a BACTEC 9240 blood culture instrument. Germ tube production, carbohydrate assimilation (API 20C AUX) and peptide nucleic acid fluorescent in situ hybridization yeast traffic light tests were performed directly from positive-signalled bottles.Time to positivity of blood cultures was affected (...) The Evaluation of Three Different Bottles in BACTEC 9240 Automated Blood Culture System and Direct Identification of Candida species to Shorten the Turnaround Time of Blood Culture. Candida spp. are the most common causes of fungemia. Rapid and accurate diagnostic methods are very important for appropriate management of candidemia. At present, blood culture is the essential diagnostic test despite having a long detection time and low sensitivity rate. We aimed to investigate the ways to shorten

2017 Journal of Medical Microbiology

138. Ovarian Epithelial, Fallopian Tube, and Primary Peritoneal Cancer Treatment (PDQ®): Patient Version

and ovaries. The doctor or nurse also inserts a lubricated, gloved finger into the rectum to feel for lumps or abnormal areas. Pelvic exam. A doctor or nurse inserts one or two lubricated, gloved fingers of one hand into the vagina and presses on the lower abdomen with the other hand. This is done to feel the size, shape, and position of the uterus and ovaries. The vagina, cervix, fallopian tubes, and rectum are also checked. : A test that measures the level of CA 125 in the blood. CA 125 is a substance (...) , fallopian tube cancer, or primary peritoneal cancer that has recurred. is a PARP inhibitor that is being studied to treat advanced ovarian cancer. are targeted therapy drugs that may the growth of new blood vessels that tumors need to grow and may kill cancer cells. is an angiogenesis inhibitor being studied in the treatment of ovarian cancer. See for more information. New types of treatment are being tested in clinical trials. This summary section describes treatments that are being studied in clinical

2016 PDQ - NCI's Comprehensive Cancer Database

139. Chest Tube

complication rates (e.g. empyemea, retained ) regardless of tube size Chest Tube Suction Apparatus or pleur-evac Cell salvage device (autotransfusion blood bag, cell-saver) for blood recovery Filtered blood (and treated with citrate phosphate dextrose) Blood may be re-transfused in for up to 6 hours after collection Replaces blood cells, platelets and (FFP) is less concentrated than packed RBC (9 g/dl compared with 13 g/dl in ) Spares utilization of allogenic blood and Similar safety to allogenic (...) suction will often drain without wall suction (blood is forced out with respirations) requires suction until no air leak remains Pleurovac contains no bubbles with respiration Do not apply a in cases of Use only for simple in a patient going home References Majoewsky (2012) EM:RAPC3 2(1): 1-2 Chest Tube removal timing At least 24 hours after air leaks have stopped AND Chest Tube drainage <200 ml per 24 hours AND Serous drainage AND Not intubated on or other form of (e.g. Bipap, CPaP) VII

2018 FP Notebook

140. Nasogastric Tube

: Discontinuing in Resolving Ileus (Adults) Instill 3 ounces via NG tube Clamp Nasogastric Tube for 8 hours Unclamp tube and aspirate residual contents Discontinue NG tube if <120 cc normally secretes several liters in a day Small suggests adeguate drainage VIII. Causes: Blood in gastric aspirate Upper gastrointestinal Oropharyngeal blood (swallowed) tic insertion Upper gastrointestinal tract injury (from insertion) IX. Complications: Nasogastric or nasoduodenal Feeding Tubes ral Self-extubation (common (...) Nasogastric Tube Nasogastric Tube Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Nasogastric Tube Nasogastric Tube Aka: Nasogastric

2018 FP Notebook

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