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Blood Collection Tube

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101. Evaluating an Education Program to Reduce Indeterminate QuantiFERON Gold In-Tube Results Full Text available with Trip Pro

emailed a link to an online pretest educational program with a QFT-G blood collection and handling presentation, and a posttest assessment.Of the 332 nurses emailed, 94 (28.4%) voluntarily completed both tests within the 6-month time allotted. The nurses that completed the education program had a significantly higher posteducation test score than on the pretest (70.2% versus 55.3%, p<0.001, effect size=0.82). Improved posttest score was seen in 67.0% of participants. No reduction in the proportion (...) of indeterminate test results was seen overall at HMH in the 6 months after education.A targeted education program was able to successfully increase nurses' knowledge of blood collection and handling procedures for the QFT-G test, but no association was found between the improvement of posttest score and indeterminate QFT-G test results.

2018 Tuberculosis research and treatment

102. Bioavailability of dexlansoprazole delayed-release capsule granules when administered via nasogastric tube or orally via syringe Full Text available with Trip Pro

nasogastric tube or orally via syringe was compared to administration of the intact capsule in the fasted state, swallowed with water. Blood samples were collected before and after dosing to determine dexlansoprazole pharmacokinetic parameter estimates and plasma concentrations.Similar values for area under the plasma concentration-time curve and observed maximum plasma concentration were achieved when the dexlansoprazole 60 mg capsule was administered as the intact capsule or when the granules were mixed (...) Bioavailability of dexlansoprazole delayed-release capsule granules when administered via nasogastric tube or orally via syringe To assess the effect of route of administration on the bioavailability of dexlansoprazole 60 mg delayed-release capsule granules.One open-label, Phase I, single-dose, 3-period crossover study was conducted in healthy adults. The bioavailability of Dexilant® (dexlansoprazole) after dexlansoprazole capsule granules were mixed with water and administered via 16 French

2018 Clinical and experimental gastroenterology Controlled trial quality: uncertain

103. Is closed thoracic drainage tube necessary for minimally invasive thoracoscopic-esophagectomy? Full Text available with Trip Pro

Is closed thoracic drainage tube necessary for minimally invasive thoracoscopic-esophagectomy? Closed thoracic drainage tube (CTDT) is a conventional treatment after esophagectomy, even after minimally invasive esophagectomy. Here, we report a single-center, retrospective study to explore the safety and necessity of CTDT after thoracoscopic-esophagectomy.From October 2015 and August 2016, 50 patients were enrolled and underwent thoracoscopic-esophagectomy in semi-prone position by same surgical (...) team. Perioperative demographic and surgical parameters, and patients' satisfaction with or without CTDT after thoracoscopic-esophagectomy were collected and analyzed.All eligible patients (18 patients without CTDT and 32 patients with CTDT) were successfully underwent thoracoscopic procedures without conversion to open approach or major intraoperative complications and perioperative death. The two groups, with similar demographic parameters, had no statistically difference in thoracic operation

2018 Journal of thoracic disease

104. Impact of diabetes mellitus on indeterminate results of the QuantiFERON TB Gold In-Tube test: A propensity score matching analysis. Full Text available with Trip Pro

retrospectively reviewed all patients who underwent QuantiFERON-TB Gold In-Tube testing (QFT-GIT) at Chonnam National University Hospital. We collected the clinical and laboratory data of these patients.Of all 3,391 subjects, 1,265 (37.3%) had a positive QFT-GIT result, 266 (7.8%) had an indeterminate result, and 1,860 (54.9%) had a negative result. The mean age was 54.8 ± 18.1 years and 55.0% of the patients were male. There were 512 (15.1%) patients with DM. Multivariable analysis revealed that systemic (...) Impact of diabetes mellitus on indeterminate results of the QuantiFERON TB Gold In-Tube test: A propensity score matching analysis. The sensitivity of interferon-gamma release assays (IGRAs) in the detection of Mycobacterium tuberculosis infection could be affected by conditions of immune dysregulation. For this reason, diabetes mellitus (DM) may increase the frequency of indeterminate results of IGRAs. However, there have been inconsistent reports of role of DM on indeterminate IGRA results.We

2017 PLoS ONE

105. Use of QuantiFERON®-TB Gold in-tube culture supernatants for measurement of antibody responses. Full Text available with Trip Pro

Use of QuantiFERON®-TB Gold in-tube culture supernatants for measurement of antibody responses. QuantiFERON®-TB Gold in-tube (QFT-GIT) supernatants may be important samples for use in assessment of anti-tuberculosis (TB) antibodies when only limited volumes of blood can be collected and when a combination of antibody and cytokine measurements are required. These analytes, when used together, may also have the potential to differentiate active pulmonary TB (APTB) from latent TB infection (LTBI (...) ). However, few studies have explored the use of QFT-GIT supernatants for investigations of antibody responses. This study determined the correlation and agreement between anti-CFP-10 and anti-ESAT-6 antibody concentrations in QFT-GIT nil supernatant and serum pairs from 68 TB household contacts. We also explored the ability of Mycobacterium tuberculosis (M.tb) specific antibodies, or ratios of antibody to interferon gamma (IFN-γ) in QFT-GIT supernatants, to differentiate 97 APTB cases from 58

2017 PLoS ONE

106. Active Chest Tube Clearance After Cardiac Surgery is Associated with Reduced Reexploration Rates. Full Text available with Trip Pro

Active Chest Tube Clearance After Cardiac Surgery is Associated with Reduced Reexploration Rates. Ineffective evacuation of intrathoracic fluid after cardiac surgery (retained blood syndrome [RBS]) might increase postoperative complications, morbidity, and mortality. Active tube clearance (ATC) technology using an intraluminal clearing apparatus aims at increasing chest tube drainage efficiency. This study evaluated whether ATC reduces RBS in an all-comers collective undergoing scheduled (...) patients (21%) was higher compared with patients without RBS (3.9%, p < 0.001). Among the RBS components, only reexploration (odds ratio 16, 95% confidence interval: 5.8 to 43, p < 0.001) was relevant for inhospital mortality (ATC 6.8%, control 7.7%; p = 0.71).Active tube clearance is associated with reduced reexploration rates in an all-comers collective undergoing cardiac surgery. Reexploration is the only RBS component relevant for mortality. The ATC effect does not translate into improved overall

2018 Annals of Thoracic Surgery

107. Small-Volume Tubes to Reduce Anemia and Transfusion

Information provided by (Responsible Party): Population Health Research Institute Study Details Study Description Go to Brief Summary: STRATUS will evaluate the use of small-volume ("soft-draw") blood collection tubes for laboratory testing in reducing anemia and transfusion in intensive care unit patients without significant adverse consequences. This is a simple, cost-neutral intervention that could improve the quality of patient care and reduce the harms of frequent laboratory testing. Condition (...) or disease Intervention/treatment Phase Blood Loss Anemia Device: Small-Volume Blood Collection Tubes Device: Standard-Volume Blood Collection Tubes Not Applicable Detailed Description: Blood sampling can cause significant unnecessary blood loss particularly in the intensive care unit (ICU). Blood loss contributes to anemia which is highly prevalent in the ICU and is associated with major adverse cardiovascular outcomes and death. Red blood cell (RBC) transfusions to correct anemia also have significant

2018 Clinical Trials

108. Adavosertib With or Without Olaparib in Treating Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Adavosertib With or Without Olaparib in Treating Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Adavosertib With or Without Olaparib in Treating Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have (...) reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Adavosertib With or Without Olaparib in Treating Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before

2018 Clinical Trials

109. Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer

. Progression-free survival [ Time Frame: From start of treatment up to 1 year after completion of study treatment ] Progression-free survival determined by Kaplan-Meier curves. Other Outcome Measures: Pharmacokinetics of mirvetuximab soravtansine and rucaparib in combination Cmax trough concentrations [ Time Frame: predose and post dose at selected times ] Pharmacokinetics determined by analysis of collected blood samples Eligibility Criteria Go to Information from the National Library of Medicine Choosing (...) Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record

2018 Clinical Trials

110. Paclitaxel + Carboplatin With AVB-S6-500 in Women With Stage III or IV Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Receiving Neoadjuvant Chemotherapy

Procedure: Tissue from Diagnostic Laparoscopy Procedure: Tissue from Core biopsy Procedure: Interval Debulking Procedure: Peripheral blood Procedure: Ascites collection Phase 1 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 30 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Phase IB Study of Paclitaxel + Carboplatin With AVB-S6-500 in Women With Stage (...) of care procedure but research specimens will be collected Procedure: Interval Debulking Standard of Care Research tissue samples will be collected Procedure: Peripheral blood -Before initiation of neoadjuvant chemotherapy and at the time of interval debulking surgery either pre-operatively, intraoperatively, or post-operatively. Procedure: Ascites collection -A total of 25-100ml of ascites will be collected prior to chemotherapy treatment, if available. Outcome Measures Go to Primary Outcome Measures

2018 Clinical Trials

111. Pilot Study of Short Term Aspirin on the Biologic and Immunologic Changes of the Fallopian Tube

tubes will also be collected for future research and routine pathology purposes. Condition or disease Intervention/treatment Phase Fallopian Tube Cancer Fallopian Tube Infection Drug: Aspirin 81 mg Early Phase 1 Detailed Description: Subjects in this study will receive low dose aspirin for 14 days before undergoing surgery to remove fallopian tubes removed to determine whether aspirin decreases inflammation in the fallopian tube. Subjects will also submit blood samples at their initial visit (...) with their oncologist, at the time of surgery and at the pre-operative visit to measure inflammation markers and blood counts. A portion of the subject's fallopian tube will be collected for future research studies. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 75 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: A Surgical Window Pilot Investigation of Short Term

2018 Clinical Trials

112. Integrated sensor-augmented pump therapy systems for managing blood glucose levels in type 1 diabetes (the MiniMed Paradigm Veo system and the Vibe and G4 PLATINUM CGM system)

tubing and a cannula Integrated sensor-augmented pump therapy systems for managing blood glucose levels in type 1 diabetes (the MiniMed Paradigm Veo system and the Vibe and G4 PLATINUM CGM system) (DG21) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 11 of 50that is placed under the skin. The pump can be programmed to deliver a basal rate of insulin throughout the day, with higher infusion rates triggered by pushing (...) Integrated sensor-augmented pump therapy systems for managing blood glucose levels in type 1 diabetes (the MiniMed Paradigm Veo system and the Vibe and G4 PLATINUM CGM system) Integr Integrated sensor-augmented pump ated sensor-augmented pump ther therap apy systems for managing blood y systems for managing blood glucose le glucose lev vels in type 1 diabetes (the els in type 1 diabetes (the MiniMed P MiniMed Par aradigm V adigm Veo system and the eo system and the Vibe and G4 PLA Vibe and G4

2016 National Institute for Health and Clinical Excellence - Diagnostics Guidance

113. Administration of Blood Components Full Text available with Trip Pro

for, the wrong patient may result in ABO‐incompatible transfusions, a third of which have resulted in serious complications or death (SHOT: Bolton‐Maggs, ). All patients having a blood sample taken must be positively identified. The collection of the blood sample from the patient and the subsequent completion of details on the blood sample tube must be performed as one continuous, uninterrupted event at the patient's (bed)side involving one patient and one trained, competent and locally designated member (...) be requested for confirmation of the ABO group of a first‐time patient prior to transfusion, where this does not impede the delivery of urgent blood components. This is also recommended in the BSH guidelines on transfusion for fetuses, neonates and older children (New et al., ). Recommendations All patients having a blood sample taken must be positively identified (Grade 1C). The collection of the blood sample from the patient and the subsequent completion of details on the blood sample tube must

2017 British Committee for Standards in Haematology

114. Tympanostomy Tubes in Children Full Text available with Trip Pro

Tympanostomy Tubes in Children Clinical Practice Guideline: Tympanostomy Tubes in Children - Richard M. Rosenfeld, Seth R. Schwartz, Melissa A. Pynnonen, David E. Tunkel, Heather M. Hussey, Jeffrey S. Fichera, Alison M. Grimes, Jesse M. Hackell, Melody F. Harrison, Helen Haskell, David S. Haynes, Tae W. Kim, Denis C. Lafreniere, Katie LeBlanc, Wendy L. Mackey, James L. Netterville, Mary E. Pipan, Nikhila P. Raol, Kenneth G. Schellhase, 2013 MENU IN THIS JOURNAL Sign In Institution Society (...) and accept the terms and conditions Share URL copied to clipboard View permissions information for this article Clinical Practice Guideline: Tympanostomy Tubes in Children .entryAuthor" data-author-container-selector=".NLM_contrib-group"> Show all authors , MD, MPH 1 1Department of Otolaryngology, State University of New York Downstate Medical Center, Brooklyn, New York, USA by this author for this author , , MD, MPH 2 2Department of Otolaryngology, Virginia Mason Medical Center, Seattle, Washington, USA

2013 American Academy of Otolaryngology - Head and Neck Surgery

115. How Much Blood Could a JP Suck If a JP Could Suck Blood? Full Text available with Trip Pro

How Much Blood Could a JP Suck If a JP Could Suck Blood? Active surgical drains minimize fluid accumulation in the postoperative period. The Jackson-Pratt (JP) system consists of a silicone drain connected by flexible tubing to a bulb. When air in the bulb is evacuated, negative pressure is applied at the surgical site to aspirate fluid. The objective of this study was to determine if the evacuation method and volume of accumulated fluid affect the pressure generated by the bulb.Bulbs were (...) connected to a digital manometer under various experimental conditions. A random number generator determined the initial evacuation method for each bulb, either side-in or bottom-up. Subsequent evacuations were alternated until data was collected in triplicate for each method. Predetermined amounts of water were placed into the bulb; air was evacuated; and pressure was recorded. The digital manometer was allowed to equilibrate for 1 minute prior to data acquisition.The average amount of pressure after

2018 Laryngoscope

116. Dried Blood Spot RNA Transcriptomes Correlate with Transcriptomes Derived from Whole Blood RNA. Full Text available with Trip Pro

Dried Blood Spot RNA Transcriptomes Correlate with Transcriptomes Derived from Whole Blood RNA. Obtaining RNA from clinical samples collected in resource-limited settings can be costly and challenging. The goals of this study were to 1) optimize messenger RNA extraction from dried blood spots (DBS) and 2) determine how transcriptomes generated from DBS RNA compared with RNA isolated from blood collected in Tempus tubes. We studied paired samples collected from eight adults in rural Tanzania (...) . Venous blood was collected on Whatman 903 Protein Saver cards and in tubes with RNA preservation solution. Our optimal DBS RNA extraction used 8 × 3-mm DBS punches as the starting material, bead beater disruption at maximum speed for 60 seconds, extraction with Illustra RNAspin Mini RNA Isolation kit, and purification with Zymo RNA Concentrator kit. Spearman correlations of normalized gene counts in DBS versus whole blood ranged from 0.887 to 0.941. Bland-Altman plots did not show a trend toward over

2018 American Journal of Tropical Medicine & Hygiene

117. Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEBâ„¢ Aneurysm Embolization System

Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEBâ„¢ Aneurysm Embolization System Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03312725 Recruitment Status : Terminated (Sponsor decision) First Posted

2017 Clinical Trials

118. Biological Collection in Nephrology for the Study of the Links Between Kidney Disease, Immunity System and Cardiovascular Complications

) of the hospital, where the samples are received, techniqued and preserved, and the Center of Nephrology and Renal Transplantation of the hospital. The collection includes blood samples (whole blood, serum, plasma, total blood RNA, PBMC cells), and urine samples (fresh urine). Participation in the collection is particularly recommended for patients who require a medical renal biopsy in the Nephrology Department. Other well-phenotyped patients (well-defined renal disease diagnosis) may also participate (...) : sample Participation in NephroMIC involves additional blood samples of 5 tubes (35 mL) and an additional sample of fresh urine. Outcome Measures Go to Primary Outcome Measures : Blood and urinary biomarkers in renal disease [ Time Frame: one day ] biological assay Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn

2017 Clinical Trials

119. Comparison of Fecal Collection Methods for Microbiota Studies in Bangladesh Full Text available with Trip Pro

reproducibility, stability at ambient temperature for 4 days, and accuracy comparing a "gold standard" for fecal samples in no solution, 95% ethanol, RNAlater, postdevelopment fecal occult blood test cards, and fecal immunochemical test tubes in a study conducted in Bangladesh. Fecal occult blood test cards and fecal samples stored in 95% ethanol or RNAlater adequately preserve fecal samples in this setting. Therefore, new studies in low- and middle-income countries should include collection of fecal samples (...) into no solution, 95% ethanol, RNAlater, postdevelopment fecal occult blood test (FOBT) cards, and fecal immunochemical test (FIT) tubes. Half of the aliquots were frozen immediately at -80°C (day 0) and the remaining samples were left at ambient temperature for 96 h and then frozen (day 4). Intraclass correlation coefficients (ICC) were calculated for the relative abundances of the top three phyla, for two alpha diversity measures, and for four beta diversity measures. The duplicate samples had relatively

2017 Applied and environmental microbiology

120. Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEBâ„¢ Aneurysm Embolization System

Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEBâ„¢ Aneurysm Embolization System Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03379714 Recruitment Status : Withdrawn (Sponsor decision) First Posted

2017 Clinical Trials

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