How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

92,845 results for

Blood Products

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Blood Administration Sets for Patients Receiving Blood Products: Clinical Effectiveness and Guidelines

Blood Administration Sets for Patients Receiving Blood Products: Clinical Effectiveness and Guidelines Blood Administration Sets for Patients Receiving Blood Products: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Blood Administration Sets for Patients Receiving Blood Products: Clinical Effectiveness and Guidelines Blood Administration Sets for Patients Receiving Blood Products: Clinical Effectiveness and Guidelines Last updated: June 4, 2019 Project Number (...) : RA1034-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What is the comparative safety of straight-type blood administration sets versus Y-type blood administration sets for patients receiving blood products or blood components? What are the evidence-based guidelines regarding the selection of blood administration sets for patients receiving blood products or blood components? Key Message No relevant literature was identified regarding

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

2. Precautionary Preparation of a Backup Intravenous Line for Patients Receiving Blood Products: Guidelines

Precautionary Preparation of a Backup Intravenous Line for Patients Receiving Blood Products: Guidelines Precautionary Preparation of a Backup Intravenous Line for Patients Receiving Blood Products: Guidelines | CADTH.ca Find the information you need Precautionary Preparation of a Backup Intravenous Line for Patients Receiving Blood Products: Guidelines Precautionary Preparation of a Backup Intravenous Line for Patients Receiving Blood Products: Guidelines Last updated: June 12, 2019 Project (...) Number: RA1036-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What are the evidence-based guidelines regarding the preparation of a backup intravenous line to use in cases of adverse transfusion reactions for patients receiving blood products? Key Message No relevant evidence-based guidelines were identified regarding the preparation of a backup intravenous line to use in cases of adverse transfusion reactions for patients receiving blood

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

3. WHO public consultation on the draft proposal on principles for global consensus on the donation and management of blood, blood components and medical products of human origin

WHO public consultation on the draft proposal on principles for global consensus on the donation and management of blood, blood components and medical products of human origin WHO public consultation on the draft proposal on principles for global consensus on the donation and management of blood, blood components and medical products of human origin JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse (...) Statistics Related Links WHO public consultation on the draft proposal on principles for global consensus on the donation and management of blood, blood components and medical products of human origin View/ Open View Statistics Altmetrics Share Citation World Health Organization . (‎2017)‎. WHO public consultation on the draft proposal on principles for global consensus on the donation and management of blood, blood components and medical products of human origin. World Health Organization. . License: CC

2017 WHO

5. Blood Transfusion in Trauma: Timing and Product Ratio

Blood Transfusion in Trauma: Timing and Product Ratio Emergency Medicine > Journal Club > Archive > February 2018 Toggle navigation February 2018 Blood Transfusion in Trauma: Timing and Product Ratio Vignette It's an active early spring afternoon in the city, and you're pretty sure that just about everyone and their sister have been shot at, with most of the pour souls ending up in your TCC. As these things tend to go, The GSWs thus far are to the extremities or benign grazes (...) trauma patients receiving at least 3 units of blood product in the first 6 hours after ED admission ( ). A follow-up randomized controlled trial ( ) attempted to compare 1:1:1 (plasma:platelets:RBC) ratio to a 1:1:2 ratio among patients requiring the highest level trauma activation at any of 12 North American level 1 trauma centers who were predicted to require a massive transfusion. While the authors found no statistically significant difference in survival at 24 hours or 30 days, there was a trend

2018 Washington University Emergency Medicine Journal Club

6. Blood Product Transfusions Prior to Surgical Interventions: Clinical Effectiveness and Guidelines

Blood Product Transfusions Prior to Surgical Interventions: Clinical Effectiveness and Guidelines Blood Product Transfusions Prior to Surgical Interventions: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Blood Product Transfusions Prior to Surgical Interventions: Clinical Effectiveness and Guidelines Blood Product Transfusions Prior to Surgical Interventions: Clinical Effectiveness and Guidelines Last updated: December 11, 2018 Project Number: RB1285-000 Product

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

7. Computerised decision support systems to promote appropriate use of blood products. (PubMed)

Computerised decision support systems to promote appropriate use of blood products. This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effect of computerised decision support systems (DSSs) on transfusion practice.

Full Text available with Trip Pro

2017 Cochrane

8. Increased Risk of Mortality with Female to Male Blood Product Transfusions

Increased Risk of Mortality with Female to Male Blood Product Transfusions "Increased Risk of Mortality with Female to Male Blood Product Transfus" by Haley Robinson and Kiersten Sperry < > > > > > Title Author Date of Graduation 8-10-2019 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies Rights . Abstract Background: Blood product transfusions are one of the most common procedures in the US. These transfusions are considered safe but there is still (...) of female blood products did increase mortality among male recipients. Four of the 5 studies did show an increase in mortality among male recipients of female blood product donation. One study found increased mortality among male recipients specifically receiving multiparous female blood products. Another study reported increased mortality among male recipients receiving more than 2 units of female plasma. One study found no increased risk to male recipients receiving female blood products. Conclusion

2019 Pacific University EBM Capstone Project

9. A systematic review of blood donors' understandings and the beliefs of donors and non-donors regarding the health effects of whole blood and blood product donation

A systematic review of blood donors' understandings and the beliefs of donors and non-donors regarding the health effects of whole blood and blood product donation Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability (...) of induction of cardiac ischemia, duration of ischemia and duration of reperfusion (if applicable). ">Data to be extracted: animal model Example: Dose, timing of administration, frequency of administration, route of administration, vehicle. ">Data to be extracted: intervention of interest Example: Serum creatinine; continuous; umol/L (may be recalculated from mg/dL). ">Data to be extracted: primary outcome(s) Example: Blood urea nitrogen; continuous; mmol/L (may be recalculated from mg/dL); Renal

2019 PROSPERO

10. Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity (PubMed)

Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity Transfusion of red cell concentrates (RCCs) is associated with increased risk of adverse outcomes that may be affected by different blood manufacturing methods and the presence of extracellular vesicles (EVs). We investigated the effect of different manufacturing methods on hemolysis, residual cells, cell-derived EVs, and immunomodulatory effects on monocyte activity. Thirty-two RCC units (...) produced using whole blood filtration (WBF), red cell filtration (RCF), apheresis-derived (AD), and whole blood-derived (WBD) methods were examined (n = 8 per method). Residual platelet and white blood cells (WBCs) and the concentration, cell of origin, and characterization of EVs in RCC supernatants were assessed in fresh and stored supernatants. Immunomodulatory activity of RCC supernatants was assessed by quantifying monocyte cytokine production capacity in an in vitro transfusion model. RCF units

Full Text available with Trip Pro

2018 Blood advances

11. Analyses of sphingosine-1-phosphate in the context of transfusion: how much is in stored blood products and in patient blood? (PubMed)

Analyses of sphingosine-1-phosphate in the context of transfusion: how much is in stored blood products and in patient blood? Sphingosine-1-phosphate (S1P) is a bloodborne lipid that regulates vascular tone and endothelial permeability. S1P concentrations are reduced in critically ill patients. As hematopoietic cells produce S1P, this study intends to investigate S1P concentrations in blood products during storage and in patient plasma after blood transfusion.S1P concentrations were measured (...) concentrations in PCs and RBCc were 2.5 to 6 times higher compared to patient plasma. Plasma S1P levels in critically ill patients, however, transiently decreased after transfusion of RBCs and recover to pretransfusion values within the following 24 hours.S1P concentrations in blood products are significantly higher compared to human plasma S1P levels, even though plasma S1P levels decreased after RBC transfusion in critically ill patients and reached pretransfusion values within 24 hours.© 2019 The Authors

2019 Transfusion

12. Comparison of Heart Rate Blood Pressure Product Versus Age-Predicted Maximum Heart Rate as Predictors of Cardiovascular Events During Exercise Stress Echocardiography

Comparison of Heart Rate Blood Pressure Product Versus Age-Predicted Maximum Heart Rate as Predictors of Cardiovascular Events During Exercise Stress Echocardiography Exercise stress echocardiograms (ESEs) are a functional cardiovascular (CV) test typically used for the investigation of coronary artery disease. ESEs are often terminated at a predetermined age-predicted maximum heart rate (APMHR) to facilitate timely acquisition of ultrasound images at peak exercise. Although an APMHR of 85 (...) % is often used, this has not been validated as a suitable termination end point. Heart rate blood pressure product (HRBPP) as an established measure of myocardial work may provide a more reliable assessment of cardiac workload. The aim of this study was to assess maximal HRBPP (MHRBPP) and APMHR as markers of cardiac workload during ESE, using CV events at mean follow-up as the outcome variable. After exclusions, 712 patients being investigated for ischemic heart disease, performed an ESE to volitional

2019 EvidenceUpdates

13. Effect of Low-Dose Supplementation of Arginine Vasopressin on Need for Blood Product Transfusions in Patients With Trauma and Hemorrhagic Shock: A Randomized Clinical Trial

Effect of Low-Dose Supplementation of Arginine Vasopressin on Need for Blood Product Transfusions in Patients With Trauma and Hemorrhagic Shock: A Randomized Clinical Trial Current therapies for traumatic blood loss focus on hemorrhage control and blood volume replacement. Severe hemorrhagic shock, however, is associated with a state of arginine vasopressin (AVP) deficiency, and supplementation of this hormone may decrease the need for blood products in resuscitation.To determine whether low (...) -dose supplementation of AVP in patients with trauma (hereinafter referred to as trauma patients) and with hemorrhagic shock decreases their need for transfused blood products during resuscitation.This randomized, double-blind placebo-controlled clinical trial included adult trauma patients (aged 18-65 years) who received at least 6 U of any blood product within 12 hours of injury at a single urban level 1 trauma center from May 1, 2013, through May 31, 2017. Exclusion criteria consisted

2019 EvidenceUpdates

14. Formyl peptide receptor 1 up-regulation and formyl peptide receptor 2/3 down-regulation of blood immune cells along with defective lipoxin A4/resolvin D1 production in obstructive sleep apnea patients. (PubMed)

Formyl peptide receptor 1 up-regulation and formyl peptide receptor 2/3 down-regulation of blood immune cells along with defective lipoxin A4/resolvin D1 production in obstructive sleep apnea patients. This study aims to investigate the role of FPR 1/2/3 expressions in patients with obstructive sleep apnea (OSA).We made cross-sectional comparisons of FPR1/2/3 expressions of blood neutrophil, M1/M2a monocyte, and natural killer (NK) cell between 16 healthy subjects (HS), 16 primary snoring (PS (...) in increased FPR1/FPR2 expression ratio of M1 cells, and increased FPR1/FPR3 expression ratio of M2a cells.FPR1 over-expression and insufficiency of FPR2 and FPR3 in association with defective lipoxin A4 and resolving D1 production were associated with disease severity of OSA and its adverse consequences.

2019 PLoS ONE

15. Meta-analysis Comparing Autologous Blood-Derived Products (Including Platelet-Rich Plasma) Injection Versus Placebo in Patients With Achilles Tendinopathy

Meta-analysis Comparing Autologous Blood-Derived Products (Including Platelet-Rich Plasma) Injection Versus Placebo in Patients With Achilles Tendinopathy To compare the effectiveness of autologous blood-derived products (ABP) injection with that of placebo (sham injection, no injection, or physiotherapy alone) in patients with Achilles tendinopathy.Electronic databases, including PubMed, Scopus, EMBASE, and Cochrane Library were searched up to June 2017. All published or unpublished randomized

2018 EvidenceUpdates

16. Relations between dairy product intake and blood pressure: the INTERnational study on MAcro/micronutrients and blood Pressure. (PubMed)

Relations between dairy product intake and blood pressure: the INTERnational study on MAcro/micronutrients and blood Pressure. Epidemiologic evidence suggests that low-fat dairy consumption may lower risk of hypertension. Dairy products may be distinctly linked to health, because of differences in nutritional composition, but little is known about specific nutrients that contribute to the dairy-blood pressure (BP) association, nor to underlying kidney function.We examined cross-sectional (...) associations to BP of dairy product intakes, total and by type, from the INTERnational study on MAcro/micronutrients and blood Pressure (INTERMAP) including 2694 participants aged 40-59 years from the UK and the USA. Eight BP, four 24-h dietary recalls and two 24-h urine samples were collected during four visits. Linear regression models adjusted for lifestyle/dietary factors to estimate BP differences per 2SD higher intakes of total-and-individual-types of dairy were calculated.Multivariable linear

2018 Journal of Hypertension

17. Accurate costs of blood transfusion: a microcosting of administering blood products in the United Kingdom National Health Service. (PubMed)

Accurate costs of blood transfusion: a microcosting of administering blood products in the United Kingdom National Health Service. In an environment of limited health care resources, it is crucial for health care systems which provide blood transfusion to have accurate and comprehensive information on the costs of transfusion, incorporating not only the costs of blood products, but also their administration. Unfortunately, in many countries accurate costs for administering blood (...) are not available. Our study aimed to generate comprehensive estimates of the costs of administering transfusions for the UK National Health Service.A detailed microcosting study was used to cost two key inputs into transfusion: transfusion laboratory and nursing inputs. For each input, data collection forms were developed to capture staff time, equipment, and consumables associated with each step in the transfusion process. Costing results were combined with costs of blood product wastage to calculate the cost

2018 Transfusion

18. A Difference in Bleeding and Use of Blood and Blood Products in Patients who Were Preoperatively on Aspirin or Dual Antiplatelet Therapy Before Coronary Artery Bypass Grafting (PubMed)

A Difference in Bleeding and Use of Blood and Blood Products in Patients who Were Preoperatively on Aspirin or Dual Antiplatelet Therapy Before Coronary Artery Bypass Grafting Postoperative bleeding in patients who underwent elective coronary artery bypass surgery (CABG) may increase due to preoperative anticoagulant therapy indicative of their disease - acute coronary syndrome or implanted coronary artery stent. Increased bleeding in many cases requires the use of blood and blood derivatives (...) that there is no significant difference between the observed groups (p>0.05). Also, our study did not show a statistically significant difference between arrhythmia onset, the length of mechanical ventilation, use of protamineand tranexamic acid. Reoperation due to postoperative bleeding was recorded in 2 cases in the DAPT group as well as 2 lethal cases.In our study, we could not demonstrate less postoperative bleeding and use of blood and blood products in a group of patients who were preoperatively treated with aspirin

Full Text available with Trip Pro

2018 Medical Archives

19. Estimated injury-associated blood loss versus availability of emergency blood products at a district-level public hospital in Cape Town, South Africa (PubMed)

Estimated injury-associated blood loss versus availability of emergency blood products at a district-level public hospital in Cape Town, South Africa International guidance suggests that injury-associated haemorrhagic shock should be resuscitated using blood products. However, in low- and middle-income countries resuscitation emphasises the use of crystalloids - mainly due to poor access to blood products. This study aimed to estimate the amount of blood loss from serious injury in relation (...) to available emergency blood products at a secondary-level, public Cape Town hospital.This retrospective, cross-sectional study included all injured patients cared for in the resuscitation area of Khayelitsha Hospital's emergency centre over a fourteen-week period. Injuries were coded using the Abbreviated Injury Scale, which was then used to estimate blood loss for each patient using an algorithm from the Trauma Audit Research Network. Descriptive statistics were used to describe blood volume lost

Full Text available with Trip Pro

2018 African Journal of Emergency Medicine

20. Pentoxifylline alone or in combination with gentamicin or vancomycin inhibits live microbe-induced pro-inflammatory cytokine production in human cord blood and cord blood monocytes <i>in vitro</i>. (PubMed)

Pentoxifylline alone or in combination with gentamicin or vancomycin inhibits live microbe-induced pro-inflammatory cytokine production in human cord blood and cord blood monocytes in vitro. Neonatal sepsis and its accompanying inflammatory response contribute to substantial morbidity and mortality. Pentoxifylline (PTX), a phosphodiesterase inhibitor which suppresses transcription and production of proinflammatory cytokines, is a candidate adjunctive therapy for newborn sepsis. We (...) hypothesized that PTX decreases live microbe-induced inflammatory cytokine production in newborn blood. Cord blood was stimulated with live microorganisms commonly encountered in newborn sepsis (Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, or Candida albicans) and simultaneously treated with antimicrobial agents (gentamicin, vancomycin, or amphotericin B) and/or clinically relevant concentrations of PTX. Microbial colony counts were enumerated by plating, supernatant cytokines were

2018 Antimicrobial Agents and Chemotherapy

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>